NO2001005I2 - 5-Ä4-Ä2-(N-metyl-N-(2-pyridyl)amino)etoksy)benzyl)tiazolidin-2,4dion, maleinsyresalt - Google Patents

5-Ä4-Ä2-(N-metyl-N-(2-pyridyl)amino)etoksy)benzyl)tiazolidin-2,4dion, maleinsyresalt

Info

Publication number: NO2001005I2
Authority: NO; Norway
Prior art keywords: thiazolidine; dione; pyridyl; ethoxy; benzyl
Prior art date: 1992-09-05

Application number

NO2001005C

Other languages

English (en)

Original Assignee

Smithkline Beecham Pic

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-09-05

Filing date

2001-04-10

Publication date

2004-06-01

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10721461&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO2001005(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2001-04-10 Application filed by Smithkline Beecham Pic filed Critical Smithkline Beecham Pic

2004-06-01 Publication of NO2001005I2 publication Critical patent/NO2001005I2/no

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Endocrinology (AREA)
Emergency Medicine (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Child & Adolescent Psychology (AREA)
Nutrition Science (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Thiazole And Isothizaole Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

NO2001005C 1992-09-05 2001-04-10 5-Ä4-Ä2-(N-metyl-N-(2-pyridyl)amino)etoksy)benzyl)tiazolidin-2,4dion, maleinsyresalt NO2001005I2 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB929218830A GB9218830D0 (en)	1992-09-05	1992-09-05	Novel compounds
PCT/GB1993/001853 WO1994005659A1 (en)	1992-09-05	1993-09-01	Substituted thiazolidinedione derivatives

Publications (1)

Publication Number	Publication Date
NO2001005I2 true NO2001005I2 (no)	2004-06-01

Family

ID=10721461

Family Applications (4)

Application Number	Title	Priority Date	Filing Date
NO950852A NO303016B1 (no)	1992-09-05	1995-03-03	Nye forbindelser
NO974646A NO305802B1 (no)	1992-09-05	1997-10-08	Nye forbindelser, farmas°ytiske blandinger inneholdende disse og anvendelse av disse forbindelser
NO2001005C NO2001005I2 (no)	1992-09-05	2001-04-10	5-Ä4-Ä2-(N-metyl-N-(2-pyridyl)amino)etoksy)benzyl)tiazolidin-2,4dion, maleinsyresalt
NO2001006C NO2001006I1 (no)	1992-09-05	2001-04-10	Rosiglitazonmaleat

Family Applications Before (2)

Application Number	Title	Priority Date	Filing Date
NO950852A NO303016B1 (no)	1992-09-05	1995-03-03	Nye forbindelser
NO974646A NO305802B1 (no)	1992-09-05	1997-10-08	Nye forbindelser, farmas°ytiske blandinger inneholdende disse og anvendelse av disse forbindelser

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
NO2001006C NO2001006I1 (no)	1992-09-05	2001-04-10	Rosiglitazonmaleat

Country Status (38)

Country	Link
US (1)	US5910592A (no)
EP (2)	EP0658161B1 (no)
JP (5)	JP2828777B2 (no)
KR (3)	KR100371297B1 (no)
CN (4)	CN1040323C (no)
AP (1)	AP513A (no)
AT (1)	ATE182147T1 (no)
AU (1)	AU674880B2 (no)
BR (1)	BR1100916A (no)
CA (2)	CA2273147A1 (no)
CY (1)	CY2138B1 (no)
CZ (2)	CZ287473B6 (no)
DE (2)	DE69325658T2 (no)
DK (1)	DK0658161T3 (no)
ES (1)	ES2133410T3 (no)
FI (2)	FI106263B (no)
GB (1)	GB9218830D0 (no)
GR (1)	GR3030794T3 (no)
HK (1)	HK1012363A1 (no)
HU (2)	HU224212B1 (no)
IL (1)	IL106904A (no)
LU (1)	LU90712I2 (no)
MA (1)	MA22970A1 (no)
MX (1)	MX9305397A (no)
MY (1)	MY111190A (no)
NL (1)	NL300035I2 (no)
NO (4)	NO303016B1 (no)
NZ (1)	NZ255505A (no)
PL (1)	PL173725B1 (no)
RU (3)	RU2128179C1 (no)
SA (1)	SA93140245B1 (no)
SG (2)	SG83747A1 (no)
SI (1)	SI9300452B (no)
SK (1)	SK280777B6 (no)
TW (1)	TW385309B (no)
UA (1)	UA41901C2 (no)
WO (1)	WO1994005659A1 (no)
ZA (1)	ZA936509B (no)

Families Citing this family (108)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9308487D0 (en) *	1993-04-23	1993-06-09	Smithkline Beecham Plc	Novel compounds
US5801173A (en) *	1996-05-06	1998-09-01	Dr. Reddy's Research Foundation	Heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them
US5919782A (en) *	1996-05-06	1999-07-06	Dr. Reddy's Research Foundation	Heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them
US5889025A (en) *	1996-05-06	1999-03-30	Reddy's Research Foundation	Antidiabetic compounds having hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them
ZA973848B (en) *	1996-05-06	1997-12-02	Reddy Research Foundation	Novel heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them.
US6114526A (en) *	1996-07-01	2000-09-05	Dr. Reddy's Research Foundation	Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases
USRE39266E1 (en) *	1996-07-01	2006-09-05	Dr. Reddy's Laboratories, Limited	Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases
US6372750B2 (en)	1996-07-01	2002-04-16	Dr. Reddy's Research Foundation	Heterocyclic compounds, process for their preparation and pharmaceutical compounds containing them and their use in the treatment of diabetes and related diseases
KR100579765B1 (ko)	1996-07-01	2006-12-28	닥터 레디스 레보러터리즈 리미티드	신규헤테로고리형화합물의제조방법,이를함유하는약제조성물및당뇨병및이와관련된질병의치료에있어서그의용도
US5885997A (en) *	1996-07-01	1999-03-23	Dr. Reddy's Research Foundation	Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases
EP0921798A1 (en) *	1996-07-12	1999-06-16	Smithkline Beecham Plc	Novel treatment of leptine resistance
GB9711683D0 (en) *	1997-06-05	1997-08-06	Smithkline Beecham Plc	Composition
BR9810142A (pt) *	1997-06-18	2000-08-08	Smithkline Beecham Plc	Tratamento de diabete com tiazolidinadiona e sulfonil-uréia
PL195136B1 (pl) *	1997-06-18	2007-08-31	Smithkline Beecham Plc	Kombinacja zawierająca 5-[4-[2-(N-metylo-N-(2-pirydylo)amino)etoksy]-benzylo] tiazolidyno-2,4-dion i jej zastosowanie
GB9715306D0 (en) *	1997-07-18	1997-09-24	Smithkline Beecham Plc	Novel method of treatment
GB9721693D0 (en) *	1997-10-13	1997-12-10	Smithkline Beecham Plc	Novel treatment
GB9721692D0 (en) *	1997-10-13	1997-12-10	Smithkline Beecham Plc	Novel treatment
US20020006939A1 (en) *	1997-10-13	2002-01-17	Smithkline Beecham P.L.C.	Use of thiazolidinediones for the treatment of hyperglycaemia
US20010031776A1 (en) *	1997-10-13	2001-10-18	Smithkline Beecham P.L.C.	Use of thiazolidinediones for the treatment of hyperglycaemia
US7091359B2 (en)	1997-11-04	2006-08-15	Smithkline Beecham Plc	Process for the preparation of thiazolidinedione derivatives
GB9723295D0 (en) *	1997-11-04	1998-01-07	Smithkline Beecham Plc	Novel process
GB9726568D0 (en) *	1997-12-16	1998-02-11	Smithkline Beecham Plc	Novel pharmaceutical
GB9726566D0 (en) *	1997-12-16	1998-02-11	Smithkline Beecham Plc	Novel pharmaceutical
US20020137940A1 (en) *	1997-12-16	2002-09-26	Smithkline Beecham P.L.C.	5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2, 4-dione, maleic acid salt, hydrate as pharmaceutical
AU770817B2 (en) *	1997-12-16	2004-03-04	Smithkline Beecham Plc	5-(4-(2-(N-methyl-N-(2-pyridyl)amino)ethoxy)benzyl) thiazolidine-2,dione,maleic acid salt, hydrate as pharmaceutical
AU774613B2 (en) *	1997-12-16	2004-07-01	Smithkline Beecham Plc	Hydrate of 5-(4-(2- (N-methyl-N- (2-pyridil)amino) ethoxy)benzyl) thiazolidine-2,4-dione maleic acid salt
GB9726563D0 (en) *	1997-12-16	1998-02-11	Smithkline Beecham Plc	Novel pharmaceutical
US6664278B2 (en)	1997-12-16	2003-12-16	Smithkline Beecham P.L.C.	Hydrate of 5-[4-[2-(N-methyl-N-(2-pyridil)amino)ethoxy]benzyl]thiazolidine-2,4-dione maleic acid salt
PT1098639E (pt) *	1998-07-21	2005-06-30	Smithkline Beecham Plc	A utilizacao de intensificadores de captacao da glicose para reduzir a apoptose
MA26662A1 (fr) *	1998-07-21	2004-12-20	Smithkline Beecham Plc	Derives de thiazolidinedione, compositions pharmaceutiques les contenant et leur utilisation
US6613785B2 (en)	1998-07-21	2003-09-02	Smithkline Beecham Plc	Use of glucose uptake enhancer for reducing post-ischemic injury of the heart
EP1131070B1 (en)	1998-11-12	2008-09-03	SmithKline Beecham plc	Pharmaceutical composition for modified release of an insulin sensitiser and metformin
US20030153607A1 (en) *	1998-11-12	2003-08-14	Smithkline Beecham P.L.C.	Novel composition and use
GB9824893D0 (en) *	1998-11-12	1999-01-06	Smithkline Beckman Corp	Novel method of treatment
DZ2937A1 (fr) *	1998-11-12	2004-03-15	Smithkline Beecham Plc	Compositions nouvelles de sensibilidants à l'insuline.
US20040102486A1 (en) *	1998-11-12	2004-05-27	Smithkline Beecham Corporation	Novel method of treatment
GB9909041D0 (en) *	1999-04-20	1999-06-16	Smithkline Beecham Plc	Novel pharmaceutical
GB9909075D0 (en) *	1999-04-20	1999-06-16	Smithkline Beecham Plc	Novel pharmaceutical
US6815457B1 (en) *	1999-04-23	2004-11-09	Smithkline Beecham P.L.C.	Thiazolidinedione derivative and its use as antidiabetic
PT1173435E (pt) *	1999-04-23	2003-12-31	Smithkline Beecham Cork Ltd	Polimorfo de 5-¬4-¬2-(n-metil-n-(2-piridil)-amino)-etoxi\|benzil\|tiazolidino-2,4-diona sal de acido maleico
US20040248945A1 (en)	1999-04-23	2004-12-09	Smithkline Beecham P.L.C.	Thiazolidinedione derivative and its use as antidiabetic
MXPA01010822A (es) *	1999-04-23	2002-06-04	Smithkline Beecham Plc	Composicion farmaceutica novedosa.
TR200200438T2 (tr) *	1999-08-17	2002-05-21	Smithkline Beecham P.L.C.	Tiazolidindion türevleri içeren farmasötik terkipler ve bu terkipleri hazırlama prosesi.
AR030920A1 (es) *	1999-11-16	2003-09-03	Smithkline Beecham Plc	Composiciones farmaceuticas para el tratamiento de la diabetes mellitus y condiciones asociadas con la diabetes mellitus, y procedimientos para preparar dichas composiciones
GB0006133D0 (en) *	2000-03-14	2000-05-03	Smithkline Beecham Plc	Novel pharmaceutical
GB0014005D0 (en) *	2000-06-08	2000-08-02	Smithkline Beecham Plc	Novel pharmaceutical
GB0014006D0 (en) *	2000-06-08	2000-08-02	Smithkline Beecham Plc	Novel pharmaceutical
MXPA02012619A (es) *	2000-06-16	2003-04-10	Smithkline Beecham Plc	Tratamiento y prevencion de condiciones asociadas con resistencia a la insulina cardiaca.
GB0014969D0 (en)	2000-06-19	2000-08-09	Smithkline Beecham Plc	Novel method of treatment
GB0019228D0 (en) *	2000-08-04	2000-09-27	Smithkline Beecham Plc	Novel pharmaceutical
GB0019226D0 (en) *	2000-08-04	2000-09-27	Smithkline Beecham Plc	Novel pharmaceutical
AU2005229688B2 (en) *	2000-08-04	2008-04-03	Smithkline Beecham P.L.C.	Tartrate salts of thiazolidinedione derivative
AU2005229687B2 (en) *	2000-08-04	2008-03-13	Smithkline Beecham P.L.C.	Tartrate salts of thiazolidinedione derivative
GB0019224D0 (en) *	2000-08-04	2000-09-27	Smithkline Beecham Plc	Novel pharmaceutical
GB0019223D0 (en) *	2000-08-04	2000-09-27	Smithkline Beecham Plc	Novel pharmaceutical
GB0021784D0 (en) *	2000-09-05	2000-10-18	Smithkline Beecham Plc	Novel pharmaceutical
GB0021785D0 (en) *	2000-09-05	2000-10-18	Smithkline Beecham Plc	Novel Pharmaceutical
GB0021865D0 (en) *	2000-09-06	2000-10-18	Smithkline Beecham Plc	Novel pharmaceutical
GB0021978D0 (en)	2000-09-07	2000-10-25	Smithkline Beecham Plc	Novel pharmaceutical
MXPA03002580A (es) *	2000-09-26	2003-10-15	Cord Janet I	Nuevas formas polimorficas de maleato de 5-(4-(2-(n-metil-n-(2-piridil) amino)etoxi)bencil) tiazolidin-2, 4-diona y proceso para su preparacion.
US7241895B2 (en)	2000-09-26	2007-07-10	Dr. Reddy's Laboratories Limited	Polymorphic forms of 5-[4-[2-[n-methyl-n-(2-pyridyl)amino[ethoxy]benzyl] thiazolidine-2,4-dione maleate and process for their preparation
GB0023971D0 (en) *	2000-09-29	2000-11-15	Smithkline Beecham Plc	Novel pharmaceutical
DE60122580T2 (de) *	2000-12-22	2007-08-30	Smithkline Beecham P.L.C., Brentford	5-4'-2'-(n-methyl-n-(2-pyridyl)amino) ethoxy!benzyl!thiazolidin-2,4-dion mesylatsalz
WO2002051823A1 (en)	2000-12-26	2002-07-04	Torrent Pharmaceuticals Ltd	Process for the preparation of rosiglitazone maleate
GB0127805D0 (en)	2001-11-20	2002-01-09	Smithkline Beecham Plc	Pharmaceutical composition
DK1446404T3 (da) *	2001-11-21	2006-10-09	Smithkline Beecham Plc	Rosiglitazonedisylater og deres anvendelse som antidiabetika
EP1448559B1 (en) *	2001-11-21	2006-12-27	Smithkline Beecham Plc	5-(4-(2-(n-methyl-n-(2-pyridyl)amino)ethoxy)benzyl)thiazolidine-2,4-dione benzenesulfonate; process for its preparation; polymorphs i, ii and iii thereof; and its use as pharmaceutical active ingredient
WO2003050116A1 (en) *	2001-12-13	2003-06-19	Smithkline Beecham Plc	A 5(-4-(2-(n-methyl-n-(2-pyridil)amino)ethoxy)benzyl)thiazolidine-2,4-dione (i) 10-camphorsulphonic acid salt and use against diabetes mellitus
GB0129872D0 (en) *	2001-12-13	2002-02-06	Smithkline Beecham Plc	Novel pharmaceutical
GB0129851D0 (en) *	2001-12-13	2002-01-30	Smithkline Beecham Plc	Novel compounds
GB0129876D0 (en) *	2001-12-13	2002-02-06	Smithkline Beecham Plc	Novel pharmaceutical
WO2003050112A1 (en) *	2001-12-13	2003-06-19	Smithkline Beecham Plc	Toluenesulfonate hydrates of a thiazolidinedione derivative
GB0129871D0 (en) *	2001-12-13	2002-02-06	Smithkline Beecham Plc	Novel pharmaceutical
GB0130509D0 (en) *	2001-12-20	2002-02-06	Smithkline Beecham Plc	Novel pharmaceutical
AU2002352479A1 (en) *	2001-12-20	2003-07-09	Smithkline Beecham Plc	5- (4- (2- (n-methyl-n- (2-pyridyl) amino) ethoxy) benzyl) thiazolidine-2, 4-dione malic acid salt and use against diabetes mellitus
GB0130511D0 (en) *	2001-12-20	2002-02-06	Smithkline Beecham Plc	Novel pharmaceutical
GB0130510D0 (en) *	2001-12-20	2002-02-06	Smithkline Beecham Plc	Novel pharmaceutical
US8216609B2 (en)	2002-08-05	2012-07-10	Torrent Pharmaceuticals Limited	Modified release composition of highly soluble drugs
US8268352B2 (en)	2002-08-05	2012-09-18	Torrent Pharmaceuticals Limited	Modified release composition for highly soluble drugs
US7232828B2 (en)	2002-08-10	2007-06-19	Bethesda Pharmaceuticals, Inc.	PPAR Ligands that do not cause fluid retention, edema or congestive heart failure
WO2004062667A1 (en) *	2003-01-08	2004-07-29	Dr. Reddy's Laboratories Limited	Amorphous form of rosiglitazone maleate and process for preparation thereof
GB0307259D0 (en) *	2003-03-28	2003-05-07	Glaxo Group Ltd	Process
GB2405403A (en) *	2003-08-29	2005-03-02	Cipla Ltd	Rosiglitazone maleate of particular polymorphic forms and methods of preparing rosiglitazone free base
WO2005058813A2 (en) *	2003-12-17	2005-06-30	Ranbaxy Laboratories Limited	Thiodiazolidinedione, oxazolidinedione and diazolidinedione derivatives and their use as antidiabetic agents
WO2005065654A2 (en) *	2003-12-31	2005-07-21	Alpharma, Inc.	Rosiglitazone formulations
WO2005073227A2 (en) *	2004-01-28	2005-08-11	Usv Limited	A process for the preparation of 5-[4-[2-[n-methyl-n-(2-pyridyl) amino] ethoxy] phenyl methyl] thiazolidine-2, 4-dione maleate
AR047541A1 (es) *	2004-02-13	2006-01-25	Sandoz Ag	Fosfato de 5-[[4-[2-metil-2-piridinil-amino-etoxi]fenil]metil]-2,4 tiazolidinadiona (rosiglitazona) y sus formas polimorficas
GB2410948A (en) *	2004-02-13	2005-08-17	Sandoz Ag	Novel phosphoric acid salt of rosiglitazone
GB2421240A (en) *	2004-12-14	2006-06-21	Sandoz Ag	Phosphoric acid salt of rosiglitazone
CZ296468B6 (cs) *	2004-06-10	2006-03-15	Zentiva, A. S.	Sul kyseliny fosforecné s 5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidin-2,4-dionema zpusob její prípravy
CZ296472B6 (cs) *	2004-07-27	2006-03-15	Zentiva, A. S	Sul kyseliny stavelové s 5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidin-2,4-dionu azpusob její prípravy a její pouzití
CZ298424B6 (cs) *	2005-05-24	2007-09-26	Zentiva, A. S.	Zpusob krystalizace rosiglitazonu a jeho derivátuze smesných rozpouštedel
DE102005034406A1 (de) *	2005-07-22	2007-02-01	Ratiopharm Gmbh	Neue Salze von Rosiglitazon
KR100749219B1 (ko) *	2006-03-15	2007-08-13	건일제약 주식회사	신규한 로지글리타존 옥살산염, 이의 제조방법, 및 이를포함하는 약제학적 조성물
US7435741B2 (en)	2006-05-09	2008-10-14	Teva Pharmaceutical Industries, Ltd.	2-N{5-[[4-[2-(methyl-2-pyridinylamino) ethoxy] phenyl]methyl]-2,4-thiazolidinedione} butanedioic acid, methods of preparation and compositions with rosiglitazone maleate
CN101511364B (zh)	2006-09-07	2012-08-15	奈科明有限责任公司	用于糖尿病的治疗组合
US7645616B2 (en)	2006-10-20	2010-01-12	The University Of Hong Kong	Use of lipocalin-2 as a diagnostic marker and therapeutic target
EP1967182A1 (en) *	2007-03-07	2008-09-10	KRKA, tovarna zdravil, d.d., Novo mesto	Pharmaceutical composition comprising a salt of rosigliatazone
JP5508258B2 (ja)	2007-06-04	2014-05-28	ベングリオンユニバーシティオブザネガフリサーチアンドディベロップメントオーソリティ	トリアリール化合物および前記化合物を含む組成物
CN101167726B (zh) *	2007-10-16	2011-05-18	宁夏康亚药业有限公司	马来酸罗格列酮分散片及其制备方法
PL384446A1 (pl) *	2008-02-12	2009-08-17	Adamed Spółka Z Ograniczoną Odpowiedzialnością	Sól 5-[[4-[2-(metylo-2-pirydynyloamino)etoksy]fenylo]metylo]-2,4-tiazolidynodionu z kwasem malonowym i sposób jej wytwarzania
EP2184055A1 (en)	2008-11-07	2010-05-12	LEK Pharmaceuticals d.d.	Process for preparing solid dosage forms of rosiglitazone maleate
DE102009053562A1 (de)	2009-11-18	2011-05-19	Alfred E. Tiefenbacher (Gmbh & Co. Kg)	Rosiglitazonsuccinat enthaltende pharmazeutische Zusammensetzung
US20120094959A1 (en)	2010-10-19	2012-04-19	Bonnie Blazer-Yost	Treatment of cystic diseases
CN102532122B (zh) *	2010-12-29	2015-12-02	开封制药(集团)有限公司	酒石酸罗格列酮的制备方法
CR20160207A (es)	2013-11-05	2016-08-10	Ben Gurion Univ Of The Negev Res And Dev Authority	Compuestos para el tratamiento de la diabetes y las complicaciones que surgen de la misma enfermedad
US10034868B2 (en)	2014-11-04	2018-07-31	INSERM (Institut National de la Santé et de la Recherche Médicale)	Methods for the prevention and the treatment of rapidly progressive glomerulonephritis
IT201800002630A1 (it) *	2018-02-13	2019-08-13	Giuliani Spa	Composizione per la prevenzione e il trattamento dei disturbi della crescita dei capelli

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4197297A (en) *	1976-11-17	1980-04-08	Smithkline Corporation	6-Halo-7,8-dihydroxy-1-(hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepines
US4405211A (en) *	1980-07-29	1983-09-20	The Secretary Of State For Defence In Her Britannic Majesty's Government Of The United Kingdom Of Great Britain And Northern Ireland	Liquid crystal compositions with pleochroic anthraquinone dyes
AR240698A1 (es) *	1985-01-19	1990-09-28	Takeda Chemical Industries Ltd	Procedimiento para preparar compuestos de 5-(4-(2-(5-etil-2-piridil)-etoxi)benzil)-2,4-tiazolidindiona y sus sales
US5039687A (en) *	1985-12-04	1991-08-13	Hoechst-Roussel Pharmaceuticals Inc.	N-(pyrrol-1-yl)pyridinamine compounds having enhancing activity
ATE186724T1 (de) *	1987-09-04	1999-12-15	Beecham Group Plc	Substituierte thiazolidindionderivate
US5232925A (en) *	1987-09-04	1993-08-03	Beecham Group P.L.C.	Compounds
GB8919417D0 (en) *	1989-08-25	1989-10-11	Beecham Group Plc	Novel compounds
GB8919434D0 (en) *	1989-08-25	1989-10-11	Beecham Group Plc	Novel compounds
GB9023583D0 (en) *	1990-10-30	1990-12-12	Beecham Group Plc	Novel compounds

1992
- 1992-09-05 GB GB929218830A patent/GB9218830D0/en active Pending
1993
- 1993-09-01 RU RU95108329A patent/RU2128179C1/ru active
- 1993-09-01 AT AT93919489T patent/ATE182147T1/de active
- 1993-09-01 DE DE69325658T patent/DE69325658T2/de not_active Expired - Lifetime
- 1993-09-01 EP EP93919489A patent/EP0658161B1/en not_active Expired - Lifetime
- 1993-09-01 AU AU49730/93A patent/AU674880B2/en not_active Expired
- 1993-09-01 WO PCT/GB1993/001853 patent/WO1994005659A1/en active Application Filing
- 1993-09-01 DK DK93919489T patent/DK0658161T3/da active
- 1993-09-01 HU HU9500659A patent/HU224212B1/hu active Protection Beyond IP Right Term
- 1993-09-01 ES ES93919489T patent/ES2133410T3/es not_active Expired - Lifetime
- 1993-09-01 JP JP6506983A patent/JP2828777B2/ja not_active Expired - Lifetime
- 1993-09-01 SG SG9904980A patent/SG83747A1/en unknown
- 1993-09-01 KR KR1019950700873A patent/KR100371297B1/ko not_active IP Right Cessation
- 1993-09-01 SK SK277-95A patent/SK280777B6/sk not_active IP Right Cessation
- 1993-09-01 DE DE2001199002 patent/DE10199002I2/de active Active
- 1993-09-01 CA CA002273147A patent/CA2273147A1/en not_active Abandoned
- 1993-09-01 CA CA002143849A patent/CA2143849C/en not_active Expired - Lifetime
- 1993-09-01 KR KR1020027006870A patent/KR20030097596A/ko not_active Application Discontinuation
- 1993-09-01 EP EP99108192A patent/EP0960883A1/en not_active Ceased
- 1993-09-01 NZ NZ255505A patent/NZ255505A/xx not_active IP Right Cessation
- 1993-09-01 CZ CZ1995565A patent/CZ287473B6/cs not_active IP Right Cessation
- 1993-09-01 HU HU0500355A patent/HU0500355D0/hu not_active Application Discontinuation
- 1993-09-01 PL PL93307812A patent/PL173725B1/pl unknown
- 1993-09-01 UA UA95038295A patent/UA41901C2/uk unknown
- 1993-09-01 SG SG1996008773A patent/SG48302A1/en unknown
- 1993-09-01 KR KR1020087020116A patent/KR20080081099A/ko not_active Application Discontinuation
- 1993-09-02 AP APAP/P/1993/000562A patent/AP513A/en active
- 1993-09-02 SI SI9300452A patent/SI9300452B/sl unknown
- 1993-09-03 MA MA23279A patent/MA22970A1/fr unknown
- 1993-09-03 IL IL106904A patent/IL106904A/xx not_active IP Right Cessation
- 1993-09-03 ZA ZA936509A patent/ZA936509B/xx unknown
- 1993-09-03 MY MYPI93001778A patent/MY111190A/en unknown
- 1993-09-03 MX MX9305397A patent/MX9305397A/es unknown
- 1993-09-04 CN CN93119067A patent/CN1040323C/zh not_active Expired - Lifetime
- 1993-10-07 TW TW082108297A patent/TW385309B/zh not_active IP Right Cessation
- 1993-10-10 SA SA93140245A patent/SA93140245B1/ar unknown
1995
- 1995-03-03 FI FI951004A patent/FI106263B/fi not_active IP Right Cessation
- 1995-03-03 NO NO950852A patent/NO303016B1/no not_active IP Right Cessation
1997
- 1997-05-14 BR BR1100916-0A patent/BR1100916A/pt active IP Right Grant
- 1997-07-14 US US08/892,045 patent/US5910592A/en not_active Ceased
- 1997-10-08 NO NO974646A patent/NO305802B1/no not_active IP Right Cessation
- 1997-10-30 CN CN97122518A patent/CN1063942C/zh not_active Expired - Lifetime
- 1997-10-30 CN CN97122520A patent/CN1066939C/zh not_active Expired - Lifetime
- 1997-10-30 CN CN97122519A patent/CN1051312C/zh not_active Expired - Lifetime
- 1997-12-08 CZ CZ19973958A patent/CZ290591B6/cs not_active IP Right Cessation
1998
- 1998-06-02 JP JP10152828A patent/JPH11147885A/ja active Pending
- 1998-09-24 RU RU98117673/14A patent/RU98117673A/ru not_active Application Discontinuation
- 1998-09-24 RU RU98117628/04A patent/RU98117628A/ru not_active Application Discontinuation
- 1998-11-06 FI FI982413A patent/FI982413A0/fi unknown
- 1998-12-15 HK HK98113500A patent/HK1012363A1/xx not_active IP Right Cessation
1999
- 1999-07-15 GR GR990401864T patent/GR3030794T3/el unknown
- 1999-10-05 CY CY9900033A patent/CY2138B1/xx unknown
2001
- 2001-01-05 NL NL300035C patent/NL300035I2/nl unknown
- 2001-01-10 LU LU90712C patent/LU90712I2/fr unknown
- 2001-04-10 NO NO2001005C patent/NO2001005I2/no unknown
- 2001-04-10 NO NO2001006C patent/NO2001006I1/no unknown
- 2001-08-06 JP JP2001238154A patent/JP2002047288A/ja active Pending
2004
- 2004-05-12 JP JP2004142553A patent/JP2004359676A/ja active Pending
2008
- 2008-05-13 JP JP2008125985A patent/JP2008208142A/ja active Pending

Also Published As

Publication number	Publication date
WO1994005659A1 (en)	1994-03-17
CN1063942C (zh)	2001-04-04
CN1066939C (zh)	2001-06-13
RU98117673A (ru)	2000-07-20
CZ56595A3 (en)	1995-11-15
AP513A (en)	1996-07-30
US5910592A (en)	1999-06-08
NO303016B1 (no)	1998-05-18
NL300035I1 (nl)	2001-03-01
FI982413A (fi)	1998-11-06
FI951004A (fi)	1995-03-03
SG48302A1 (en)	1998-04-17
ZA936509B (en)	1994-06-16
AP9300562A0 (en)	1993-10-31
JP2002047288A (ja)	2002-02-12
NO305802B1 (no)	1999-07-26
AU4973093A (en)	1994-03-29
CN1183275A (zh)	1998-06-03
CZ290591B6 (cs)	2002-08-14
IL106904A (en)	1997-09-30
JP2004359676A (ja)	2004-12-24
JP2828777B2 (ja)	1998-11-25
DE69325658T2 (de)	1999-12-30
NO974646D0 (no)	1997-10-08
JPH11147885A (ja)	1999-06-02
CN1040323C (zh)	1998-10-21
ATE182147T1 (de)	1999-07-15
ES2133410T3 (es)	1999-09-16
HU224212B1 (hu)	2005-06-28
RU95108329A (ru)	1996-12-20
NO950852L (no)	1995-03-03
DE69325658D1 (de)	1999-08-19
HU0500355D0 (en)	2005-05-30
PL307812A1 (en)	1995-06-26
FI982413A0 (fi)	1998-11-06
EP0658161A1 (en)	1995-06-21
MA22970A1 (fr)	1994-04-01
NO2001006I1 (no)	2001-04-30
FI106263B (fi)	2000-12-29
CA2273147A1 (en)	1994-03-17
EP0960883A1 (en)	1999-12-01
CZ287473B6 (en)	2000-12-13
JP2008208142A (ja)	2008-09-11
HUT72639A (en)	1996-05-28
MX9305397A (es)	1995-01-31
CN1183413A (zh)	1998-06-03
HU9500659D0 (en)	1995-04-28
NZ255505A (en)	1997-08-22
GR3030794T3 (en)	1999-11-30
CY2138B1 (en)	2002-06-21
GB9218830D0 (en)	1992-10-21
RU98117628A (ru)	2000-08-20
DK0658161T3 (da)	1999-11-29
CN1051312C (zh)	2000-04-12
AU674880B2 (en)	1997-01-16
KR20080081099A (ko)	2008-09-05
FI951004A0 (fi)	1995-03-03
HK1012363A1 (en)	1999-07-30
NO950852D0 (no)	1995-03-03
KR950702982A (ko)	1995-08-23
CA2143849C (en)	2000-04-25
SI9300452A (en)	1994-06-30
SG83747A1 (en)	2001-10-16
KR100371297B1 (ko)	2003-05-09
EP0658161B1 (en)	1999-07-14
LU90712I2 (fr)	2001-03-12
UA41901C2 (uk)	2001-10-15
DE10199002I2 (de)	2001-12-13
SK280777B6 (sk)	2000-07-11
SK27795A3 (en)	1995-08-09
JPH08501095A (ja)	1996-02-06
SI9300452B (sl)	2003-02-28
NO974646L (no)	1995-03-03
IL106904A0 (en)	1993-12-28
CN1101911A (zh)	1995-04-26
CA2143849A1 (en)	1994-03-17
CN1183276A (zh)	1998-06-03
BR1100916A (pt)	2000-07-04
NL300035I2 (nl)	2001-07-02
RU2128179C1 (ru)	1999-03-27
SA93140245B1 (ar)	2005-10-15
MY111190A (en)	1999-09-30
PL173725B1 (pl)	1998-04-30
KR20030097596A (ko)	2003-12-31
TW385309B (en)	2000-03-21

Publication	Publication Date	Title
NO2001005I2 (no)	2004-06-01	5-Ä4-Ä2-(N-metyl-N-(2-pyridyl)amino)etoksy)benzyl)tiazolidin-2,4dion, maleinsyresalt
BR9706774B1 (pt)	2009-01-13	composto de n-(triazolazinil) arilsulfonamida, composiÇço herbicida, mÉtodo de controle de vegetaÇço indesejÁvel e compostos de cloreto de piridina-3-sulfonila e de 2-amino [1,2,4] triazol [1,5-c] pirimidina.
DE68915207D1 (de)	1994-06-16	Aminosäure-Derivate.
IL146111A0 (en)	2002-07-25	5-[4-[2-(n-methyl-n-(2-pyridyl) amino)ethoxy]benzyl] thiazolidine-2,4-dione, maleic acid salt
AP2000001831A0 (en)	2000-06-30	5-[4-[2-(n-methyl-n-(2-pyridyl)amino)ethoxy]benzyl]thiazolidin e-2,4-dione maleic acid salt hydrate as pharmaceutical
NO20003068L (no)	2000-06-15	Hydrat av 5-[-4-[2-(N-metyl-N-(2- pyridyl)amino)etoksy]benzyl]tiazolidin-2,4-dion-maleinsyre-salt
DE3883743D1 (de)	1993-10-07	Aminosäuren, nützlich bei Leberstörungen.
NO2009002I1 (no)	2009-03-02	5-{4-[2-(N-metyl-N-(2-pyridyl)amino)etoksy]benzyl}tiazolidin-2,4-dionmaleat(salter/solvater)+glimepirid
GC0000250A (en)	2006-11-01	5-Ä4-Ä2-(N-methyl-n-(2-pyridyl) amino) ethoxyÜ benzylÜthiazolidine-2,4-dione maleci acid salt
NO995938L (no)	2000-02-02	Blanding omfattende 5-[4-[2-(N-metyl-N-2- pyridyl)amino)etoksy]benzyl]tiazolidin-2,4-dion
NL194311B (nl)	2001-08-01	Kleurfilter, alsmede werkwijze voor het vervaardigen daarvan.
SI1315723T1 (en)	2005-10-31	The hydrochloride salt of 5(4-(2-(n-methyl-n-(2-pyridyl)amino)ethoxy)benzyl)thiazolidine-2,4-dione
DE69018816T2 (de)	1995-11-16	Aminosäurederivate.
AU2000249545A1 (en)	2000-12-28	Novel n-(2,2,2-trifluoroethyl)-4-methoxy-6-((substituted or unsubstituted) m-cyanophenoxy)-2-pyridinecarboxamide derivatives, process for the preparation thereof and herbicides
HU0700069D0 (en)	2007-03-28	Acid addition salts of 5-[4-[2-(n-methyl-n-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4-dione different from malei acid salt
IL153280A0 (en)	2003-07-06	5-(4-(2-(n-methyl-n-(2-pyridyl)amino)ethoxy)benzyl)thiazolidine-2,4 dione hydriodide as pharmaceutical
NO934881D0 (no)	1993-12-29	Benzotiazolderivater, fremgangsmaate for deres fremstilling og far masoeytisk preparat derav
AU2002222305A1 (en)	2002-07-08	5-'4-'2-(n-methyl-n- (2-pyridyl)amino)ethoxy!benzyl!thiazolidine-2, 4-dione mesylate salt
ATE105549T1 (de)	1994-05-15	Aminosaeure-derivate.
TR27813A (tr)	1995-08-29	Koyulastirilmis asit mikroemülsiyon terkibi.
PT102339A (pt)	1999-12-31	Sal hidrocloreto de um derivado de tiazolidinodiona substituido