IL106904A - Pyridylamino- ethoxybenzyl- thiazolidine-2, 4-dione derivatives, their preparation and pharmaceutical compositions containing them - Google Patents

Pyridylamino- ethoxybenzyl- thiazolidine-2, 4-dione derivatives, their preparation and pharmaceutical compositions containing them

Info

Publication number
IL106904A
IL106904A IL106904A IL10690493A IL106904A IL 106904 A IL106904 A IL 106904A IL 106904 A IL106904 A IL 106904A IL 10690493 A IL10690493 A IL 10690493A IL 106904 A IL106904 A IL 106904A
Authority
IL
Israel
Prior art keywords
ethoxybenzyl
pyridylamino
thiazolidine
preparation
pharmaceutical compositions
Prior art date
Application number
IL106904A
Other languages
English (en)
Other versions
IL106904A0 (en
Inventor
Colin R Pool
Robin S Roman
Malcolm D Brightwell
Alan W Tremper
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10721461&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL106904(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of IL106904A0 publication Critical patent/IL106904A0/xx
Publication of IL106904A publication Critical patent/IL106904A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
IL106904A 1992-09-05 1993-09-03 Pyridylamino- ethoxybenzyl- thiazolidine-2, 4-dione derivatives, their preparation and pharmaceutical compositions containing them IL106904A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB929218830A GB9218830D0 (en) 1992-09-05 1992-09-05 Novel compounds

Publications (2)

Publication Number Publication Date
IL106904A0 IL106904A0 (en) 1993-12-28
IL106904A true IL106904A (en) 1997-09-30

Family

ID=10721461

Family Applications (1)

Application Number Title Priority Date Filing Date
IL106904A IL106904A (en) 1992-09-05 1993-09-03 Pyridylamino- ethoxybenzyl- thiazolidine-2, 4-dione derivatives, their preparation and pharmaceutical compositions containing them

Country Status (38)

Country Link
US (1) US5910592A (xx)
EP (2) EP0658161B1 (xx)
JP (5) JP2828777B2 (xx)
KR (3) KR20080081099A (xx)
CN (4) CN1040323C (xx)
AP (1) AP513A (xx)
AT (1) ATE182147T1 (xx)
AU (1) AU674880B2 (xx)
BR (1) BR1100916A (xx)
CA (2) CA2273147A1 (xx)
CY (1) CY2138B1 (xx)
CZ (2) CZ287473B6 (xx)
DE (2) DE69325658T2 (xx)
DK (1) DK0658161T3 (xx)
ES (1) ES2133410T3 (xx)
FI (2) FI106263B (xx)
GB (1) GB9218830D0 (xx)
GR (1) GR3030794T3 (xx)
HK (1) HK1012363A1 (xx)
HU (2) HU224212B1 (xx)
IL (1) IL106904A (xx)
LU (1) LU90712I2 (xx)
MA (1) MA22970A1 (xx)
MX (1) MX9305397A (xx)
MY (1) MY111190A (xx)
NL (1) NL300035I2 (xx)
NO (4) NO303016B1 (xx)
NZ (1) NZ255505A (xx)
PL (1) PL173725B1 (xx)
RU (3) RU2128179C1 (xx)
SA (1) SA93140245B1 (xx)
SG (2) SG83747A1 (xx)
SI (1) SI9300452B (xx)
SK (1) SK280777B6 (xx)
TW (1) TW385309B (xx)
UA (1) UA41901C2 (xx)
WO (1) WO1994005659A1 (xx)
ZA (1) ZA936509B (xx)

Families Citing this family (108)

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US6372750B2 (en) 1996-07-01 2002-04-16 Dr. Reddy's Research Foundation Heterocyclic compounds, process for their preparation and pharmaceutical compounds containing them and their use in the treatment of diabetes and related diseases
USRE39266E1 (en) * 1996-07-01 2006-09-05 Dr. Reddy's Laboratories, Limited Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases
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US6114526A (en) * 1996-07-01 2000-09-05 Dr. Reddy's Research Foundation Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases
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US20020137940A1 (en) 1997-12-16 2002-09-26 Smithkline Beecham P.L.C. 5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2, 4-dione, maleic acid salt, hydrate as pharmaceutical
GB9726563D0 (en) * 1997-12-16 1998-02-11 Smithkline Beecham Plc Novel pharmaceutical
US6664278B2 (en) 1997-12-16 2003-12-16 Smithkline Beecham P.L.C. Hydrate of 5-[4-[2-(N-methyl-N-(2-pyridil)amino)ethoxy]benzyl]thiazolidine-2,4-dione maleic acid salt
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US6613785B2 (en) 1998-07-21 2003-09-02 Smithkline Beecham Plc Use of glucose uptake enhancer for reducing post-ischemic injury of the heart
MA26662A1 (fr) * 1998-07-21 2004-12-20 Smithkline Beecham Plc Derives de thiazolidinedione, compositions pharmaceutiques les contenant et leur utilisation
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US20040102486A1 (en) * 1998-11-12 2004-05-27 Smithkline Beecham Corporation Novel method of treatment
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GB9909041D0 (en) * 1999-04-20 1999-06-16 Smithkline Beecham Plc Novel pharmaceutical
EP1175418A2 (en) * 1999-04-23 2002-01-30 Smithkline Beecham Plc Thiazolidinedione derivative and its use as antidiabetic
US20040248945A1 (en) 1999-04-23 2004-12-09 Smithkline Beecham P.L.C. Thiazolidinedione derivative and its use as antidiabetic
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GB0019228D0 (en) * 2000-08-04 2000-09-27 Smithkline Beecham Plc Novel pharmaceutical
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DE69325658D1 (de) 1999-08-19
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AP9300562A0 (en) 1993-10-31
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