US20030225254A1
(en)
*
|
1989-08-07 |
2003-12-04 |
Rathjen Deborah Ann |
Tumour necrosis factor binding ligands
|
DE10399036I1
(de)
*
|
1989-08-07 |
2004-04-01 |
Peptide Technology Ltd |
Bindeligande für Tumornekrosisfaktor.
|
US5959087A
(en)
*
|
1989-08-07 |
1999-09-28 |
Peptide Technology, Ltd. |
Tumour necrosis factor binding ligands
|
US7192584B2
(en)
|
1991-03-18 |
2007-03-20 |
Centocor, Inc. |
Methods of treating psoriasis with anti-TNF antibodies
|
US6270766B1
(en)
|
1992-10-08 |
2001-08-07 |
The Kennedy Institute Of Rheumatology |
Anti-TNF antibodies and methotrexate in the treatment of arthritis and crohn's disease
|
US6830751B1
(en)
*
|
1994-03-14 |
2004-12-14 |
Genetics Institute, Llc |
Use of IL-12 antagonists in the treatment of rheumatoid arthritis
|
ZA95960B
(en)
*
|
1994-03-14 |
1995-10-10 |
Genetics Inst |
Use of interleukin-12 antagonists in the treatment of autoimmune diseases
|
US20010055581A1
(en)
|
1994-03-18 |
2001-12-27 |
Lawrence Tamarkin |
Composition and method for delivery of biologically-active factors
|
US6090382A
(en)
*
|
1996-02-09 |
2000-07-18 |
Basf Aktiengesellschaft |
Human antibodies that bind human TNFα
|
SI9720020B
(en)
*
|
1996-02-09 |
2001-12-31 |
Basf Ag |
Human antibodies that bind human TNF alpha
|
US7129061B1
(en)
*
|
1996-08-07 |
2006-10-31 |
Biogen Idec Ma Inc. |
Tumor necrosis factor related ligand
|
EP0981548A4
(en)
*
|
1997-04-30 |
2005-11-23 |
Enzon Inc |
SINGLE CHAIN PROTEINS FIXING ANTIGENS CAPABLE OF GLYCOSYLATION, PRODUCTION AND USES THEREOF
|
US20040009166A1
(en)
*
|
1997-04-30 |
2004-01-15 |
Filpula David R. |
Single chain antigen-binding polypeptides for polymer conjugation
|
US7229841B2
(en)
|
2001-04-30 |
2007-06-12 |
Cytimmune Sciences, Inc. |
Colloidal metal compositions and methods
|
US6407218B1
(en)
|
1997-11-10 |
2002-06-18 |
Cytimmune Sciences, Inc. |
Method and compositions for enhancing immune response and for the production of in vitro mabs
|
US7067144B2
(en)
*
|
1998-10-20 |
2006-06-27 |
Omeros Corporation |
Compositions and methods for systemic inhibition of cartilage degradation
|
AU780031B2
(en)
|
1998-12-14 |
2005-02-24 |
Genetics Institute, Llc |
Cytokine receptor chain
|
US7553487B2
(en)
|
1998-12-14 |
2009-06-30 |
Genetics Institute, Llc |
Method and compositions for treating asthma
|
CA2364026C
(en)
*
|
1999-03-02 |
2012-08-21 |
Centocor, Inc. |
Anti-tnf.alpha. antibodies in therapy of asthma
|
US6914128B1
(en)
|
1999-03-25 |
2005-07-05 |
Abbott Gmbh & Co. Kg |
Human antibodies that bind human IL-12 and methods for producing
|
US20040220103A1
(en)
|
1999-04-19 |
2004-11-04 |
Immunex Corporation |
Soluble tumor necrosis factor receptor treatment of medical disorders
|
JP2003511355A
(ja)
*
|
1999-10-06 |
2003-03-25 |
ビーエーエスエフ アクチェンゲゼルシャフト |
併用療法のためのエンドセリンシグナル伝達経路のインヒビターおよびαvβ3受容体アンタゴニスト
|
NZ520392A
(en)
|
2000-02-10 |
2005-04-29 |
Abbott Lab |
Antibodies that bind human interleukin-18 and methods of making and using
|
GB0013810D0
(en)
|
2000-06-06 |
2000-07-26 |
Celltech Chiroscience Ltd |
Biological products
|
KR20080074231A
(ko)
|
2000-06-29 |
2008-08-12 |
아보트 러보러터리즈 |
이중 특이성 항체 및 이의 제조 및 사용 방법
|
UA81743C2
(uk)
*
|
2000-08-07 |
2008-02-11 |
Центокор, Инк. |
МОНОКЛОНАЛЬНЕ АНТИТІЛО ЛЮДИНИ, ЩО СПЕЦИФІЧНО ЗВ'ЯЗУЄТЬСЯ З ФАКТОРОМ НЕКРОЗУ ПУХЛИН АЛЬФА (ФНПα), ФАРМАЦЕВТИЧНА КОМПОЗИЦІЯ, ЩО ЙОГО МІСТИТЬ, ТА СПОСІБ ЛІКУВАННЯ РЕВМАТОЇДНОГО АРТРИТУ
|
US20050196755A1
(en)
*
|
2000-11-17 |
2005-09-08 |
Maurice Zauderer |
In vitro methods of producing and identifying immunoglobulin molecules in eukaryotic cells
|
AU2002231736A1
(en)
|
2000-12-22 |
2002-07-08 |
Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. |
Use of repulsive guidance molecule (rgm) and its modulators
|
US20090137416A1
(en)
|
2001-01-16 |
2009-05-28 |
Regeneron Pharmaceuticals, Inc. |
Isolating Cells Expressing Secreted Proteins
|
DE60211329T2
(de)
*
|
2001-01-16 |
2007-05-24 |
Regeneron Pharmaceuticals, Inc. |
Isolierung von sezernierte proteine exprimierenden zellen
|
JP2005508608A
(ja)
|
2001-03-22 |
2005-04-07 |
アボット ゲーエムベーハー ウント カンパニー カーゲー |
問題遺伝子に対して特異的な抗体を発現するトランスジェニック動物及びその使用
|
US6410955B1
(en)
*
|
2001-04-19 |
2002-06-25 |
Micron Technology, Inc. |
Comb-shaped capacitor for use in integrated circuits
|
CA2868614A1
(en)
*
|
2001-06-08 |
2002-12-08 |
Abbott Laboratories (Bermuda) Ltd. |
Methods of administering anti-tnf.alpha. antibodies
|
WO2003002187A2
(en)
*
|
2001-06-26 |
2003-01-09 |
Photomed Technologies, Inc. |
Multiple wavelength illuminator
|
CA2451955C
(en)
|
2001-06-26 |
2015-09-29 |
Abgenix, Inc. |
Antibodies to opgl
|
US20050271663A1
(en)
*
|
2001-06-28 |
2005-12-08 |
Domantis Limited |
Compositions and methods for treating inflammatory disorders
|
TWI327597B
(en)
|
2001-08-01 |
2010-07-21 |
Centocor Inc |
Anti-tnf antibodies, compositions, methods and uses
|
AU2002341766A1
(en)
*
|
2001-09-20 |
2003-04-01 |
Genstar Therapeutics Corporation |
Improved methods for treatment with viral vectors
|
US20030065382A1
(en)
*
|
2001-10-02 |
2003-04-03 |
Fischell Robert E. |
Means and method for the treatment of coronary artery obstructions
|
EP1432431B1
(en)
|
2001-10-04 |
2017-05-10 |
Genetics Institute LLC |
Methods and compositions for modulating interleukin-21 activity
|
WO2003083071A2
(en)
*
|
2002-03-26 |
2003-10-09 |
Centocor, Inc. |
Diabetes-related immunoglobulin derived proteins, compositions, methods and uses
|
US20040009172A1
(en)
*
|
2002-04-26 |
2004-01-15 |
Steven Fischkoff |
Use of anti-TNFalpha antibodies and another drug
|
US20030206898A1
(en)
*
|
2002-04-26 |
2003-11-06 |
Steven Fischkoff |
Use of anti-TNFalpha antibodies and another drug
|
US20090280065A1
(en)
*
|
2006-04-10 |
2009-11-12 |
Willian Mary K |
Uses and Compositions for Treatment of Psoriasis
|
NZ555692A
(en)
|
2002-07-19 |
2009-02-28 |
Abbott Biotech Ltd |
Treatment of TNF alpha related disorders
|
US20040033228A1
(en)
*
|
2002-08-16 |
2004-02-19 |
Hans-Juergen Krause |
Formulation of human antibodies for treating TNF-alpha associated disorders
|
WO2004019861A2
(en)
*
|
2002-08-28 |
2004-03-11 |
Pharmacia Corporation |
Stable ph optimized formulation of a modified antibody
|
MY150740A
(en)
*
|
2002-10-24 |
2014-02-28 |
Abbvie Biotechnology Ltd |
Low dose methods for treating disorders in which tnf? activity is detrimental
|
US20060034845A1
(en)
|
2002-11-08 |
2006-02-16 |
Karen Silence |
Single domain antibodies directed against tumor necrosis factor alpha and uses therefor
|
WO2004041865A2
(en)
*
|
2002-11-08 |
2004-05-21 |
Ablynx N.V. |
Stabilized single domain antibodies
|
US9320792B2
(en)
|
2002-11-08 |
2016-04-26 |
Ablynx N.V. |
Pulmonary administration of immunoglobulin single variable domains and constructs thereof
|
US20040101939A1
(en)
*
|
2002-11-22 |
2004-05-27 |
Santora Ling C. |
Method for reducing or preventing modification of a polypeptide in solution
|
US20040162414A1
(en)
*
|
2002-11-22 |
2004-08-19 |
Santora Ling C. |
Method for reducing or preventing modification of a polypeptide in solution
|
ES2347239T3
(es)
|
2002-12-02 |
2010-10-27 |
Amgen Fremont Inc. |
Anticuerpos dirigidos al factor de necrosis tumoral y usos de los mismos.
|
JP2006517191A
(ja)
*
|
2002-12-30 |
2006-07-20 |
アムジエン・インコーポレーテツド |
共刺激因子を用いた併用療法
|
US7101978B2
(en)
*
|
2003-01-08 |
2006-09-05 |
Applied Molecular Evolution |
TNF-α binding molecules
|
JP2007525409A
(ja)
*
|
2003-01-08 |
2007-09-06 |
アプライド モレキュラー エボリューション,インコーポレイテッド |
TNF−α結合分子
|
CN101412759A
(zh)
*
|
2003-01-10 |
2009-04-22 |
埃博灵克斯股份有限公司 |
治疗性多肽,其同源物、其片段及其在调节血小板介导的聚集方面的应用
|
DE10303974A1
(de)
|
2003-01-31 |
2004-08-05 |
Abbott Gmbh & Co. Kg |
Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung
|
RU2005131852A
(ru)
*
|
2003-03-14 |
2006-04-20 |
Уайт (Us) |
Антитела против человеческого рецептора il-21 и их применение
|
EP1460088A1
(en)
|
2003-03-21 |
2004-09-22 |
Biotest AG |
Humanized anti-CD4 antibody with immunosuppressive properties
|
WO2004098578A2
(en)
*
|
2003-05-12 |
2004-11-18 |
Altana Pharma Ag |
Composition comprising a pde4 inhibitor and a tnf-alfa antagonist selected from infliximab, adalimumab, cdp870 and cdp517
|
FR2856075B1
(fr)
*
|
2003-06-16 |
2007-10-12 |
Monoclonal Antibodies Therapeu |
Procede essentiellement automatise de criblage a grande echelle de cellules secretant des anticorps monoclonaux
|
FR2859725B1
(fr)
*
|
2003-09-16 |
2006-03-10 |
Neovacs |
Procede a haut rendement pour l'obtention d'anticorps humains neutralisant l'activite biologique d'une cytokine humaine
|
US20050100965A1
(en)
|
2003-11-12 |
2005-05-12 |
Tariq Ghayur |
IL-18 binding proteins
|
KR100772800B1
(ko)
*
|
2003-11-17 |
2007-11-01 |
주식회사유한양행 |
인간 종양괴사인자 α를 인식하는 단일클론항체의가변영역 및 이를 코딩하는 유전자
|
JP2008504216A
(ja)
|
2003-12-02 |
2008-02-14 |
サイトイミューン サイエンシズ インコーポレイテッド |
モノクローナル抗体の生成のための方法および組成物
|
SG10201900535UA
(en)
|
2003-12-23 |
2019-02-27 |
Genentech Inc |
Novel anti-il 13 antibodies and uses thereof
|
US7435799B2
(en)
*
|
2004-01-08 |
2008-10-14 |
Applied Molecular Evolution |
TNF-α binding molecules
|
WO2005092926A2
(en)
|
2004-03-19 |
2005-10-06 |
Amgen Inc. |
Reducing the risk of human and anti-human antibodies through v gene manipulation
|
US7625549B2
(en)
|
2004-03-19 |
2009-12-01 |
Amgen Fremont Inc. |
Determining the risk of human anti-human antibodies in transgenic mice
|
TW201705980A
(zh)
|
2004-04-09 |
2017-02-16 |
艾伯維生物技術有限責任公司 |
用於治療TNFα相關失調症之多重可變劑量療法
|
CN100427504C
(zh)
*
|
2004-06-02 |
2008-10-22 |
北京天广实生物技术有限公司 |
TNFα高亲和力嵌合抗体及其用途
|
AR049390A1
(es)
|
2004-06-09 |
2006-07-26 |
Wyeth Corp |
Anticuerpos contra la interleuquina-13 humana y usos de los mismos
|
US7501121B2
(en)
|
2004-06-17 |
2009-03-10 |
Wyeth |
IL-13 binding agents
|
GB0414054D0
(en)
|
2004-06-23 |
2004-07-28 |
Owen Mumford Ltd |
Improvements relating to automatic injection devices
|
EP1773394A2
(en)
*
|
2004-08-05 |
2007-04-18 |
Wyeth a Corporation of the State of Delaware |
Antagonizing interleukin-21 receptor activity
|
EP1807111A4
(en)
*
|
2004-10-08 |
2009-05-27 |
Abbott Biotech Ltd |
SYNCYTIAL RESPIRATORY VIRUS INFECTION (RSV)
|
US7968308B2
(en)
*
|
2004-10-22 |
2011-06-28 |
Danisco Us Inc. |
Isolating human antibodies
|
EP1827491A4
(en)
|
2004-11-19 |
2010-07-14 |
Biogen Idec Inc |
TREATMENT OF MULTIPLE SCLEROSIS
|
ES2711213T3
(es)
|
2005-02-08 |
2019-04-30 |
Genzyme Corp |
Anticuerpos de TGFbeta
|
BRPI0608210A2
(pt)
*
|
2005-02-14 |
2010-11-09 |
Wyeth Corp |
métodos de diagnóstico de um distúrbio relacionado com il-17f em um indivìduo e de seleção de compostos capazes de inibirem a ligação de il-17f em il-17r, uso de um antagonista de il-17f, composição farmacêutica, e, adjuvante de vacina
|
AU2006214473A1
(en)
*
|
2005-02-14 |
2006-08-24 |
Wyeth |
Interleukin-17F antibodies and other IL-17F signaling antagonists and uses therefor
|
EP1859277A4
(en)
|
2005-02-17 |
2010-03-17 |
Biogen Idec Inc |
TREATMENT OF NEUROLOGICAL DISORDERS
|
GT200600148A
(es)
*
|
2005-04-14 |
2006-11-22 |
|
Metodos para el tratamiento y la prevencion de fibrosis
|
JP5339901B2
(ja)
*
|
2005-05-10 |
2013-11-13 |
バイオジェン・アイデック・エムエイ・インコーポレイテッド |
炎症傷害の処置および評価
|
AU2012254978C1
(en)
*
|
2005-05-16 |
2017-06-01 |
Abbvie Biotechnology Ltd |
Use of TNF inhibitor for treatment of erosive polyarthritis
|
CN101500607B
(zh)
*
|
2005-05-16 |
2013-11-27 |
阿布维生物技术有限公司 |
TNFα抑制剂治疗腐蚀性多关节炎的用途
|
AU2006254971A1
(en)
*
|
2005-06-06 |
2006-12-14 |
Wyeth |
Expression profiles of peripheral blood mononuclear cells for inflammatory bowel diseases
|
NZ563580A
(en)
|
2005-06-07 |
2010-09-30 |
Esbatech An Alcon Biomedical R |
Stable and soluble antibodies inhibiting TNFaplha
|
EP1909831A4
(en)
|
2005-06-14 |
2013-02-20 |
Amgen Inc |
PREPARATIONS OF SPONTANEOUS TAMPING PROTEINS
|
US20060286108A1
(en)
*
|
2005-06-16 |
2006-12-21 |
Bell Katherine A |
Topical compositions for the treatment of chronic wounds
|
US20080045949A1
(en)
*
|
2005-06-17 |
2008-02-21 |
Hunt Margaret M |
Method of treating degenerative spinal disorders
|
CA2613355C
(en)
*
|
2005-06-24 |
2014-04-22 |
Duke University |
A direct drug delivery system based on thermally responsive biopolymers
|
EP1910550A4
(en)
|
2005-07-21 |
2009-11-04 |
Abbott Lab |
MULTIGENIC EXPRESSION COMPRISING SORF CONSTRUCTS AND METHODS USING POLYPROTEINS, PRO-PROTEINS, AND PROTEOLYSIS
|
TW200726776A
(en)
*
|
2005-07-29 |
2007-07-16 |
Friedrich Alexander University Of Erlangen Nuremberg |
CD33-specific single-chain immunotoxin and methods of use
|
AU2006283532B2
(en)
|
2005-08-19 |
2012-04-26 |
Abbvie Inc. |
Dual variable domain immunoglobin and uses thereof
|
EP2500353A3
(en)
|
2005-08-19 |
2012-10-10 |
Abbott Laboratories |
Dual variable domain immunoglobulin and uses thereof
|
US20070041905A1
(en)
|
2005-08-19 |
2007-02-22 |
Hoffman Rebecca S |
Method of treating depression using a TNF-alpha antibody
|
US7612181B2
(en)
*
|
2005-08-19 |
2009-11-03 |
Abbott Laboratories |
Dual variable domain immunoglobulin and uses thereof
|
US20090215992A1
(en)
*
|
2005-08-19 |
2009-08-27 |
Chengbin Wu |
Dual variable domain immunoglobulin and uses thereof
|
WO2007039256A2
(de)
|
2005-09-30 |
2007-04-12 |
Abbott Gmbh & Co. Kg |
Bindungsdomänen von proteinen der repulsive guidance molecule (rgm) proteinfamilie und funktionale fragmente davon sowie deren verwendung
|
WO2007049286A1
(en)
*
|
2005-10-27 |
2007-05-03 |
Tata Memorial Centre |
A system for ex-vivo separation of apoptotic chromatin particles from blood or plasma
|
TW201337266A
(zh)
|
2005-11-01 |
2013-09-16 |
Abbott Biotech Ltd |
利用生物標記診斷關節黏連脊椎炎之方法及組合物
|
PE20070684A1
(es)
|
2005-11-14 |
2007-08-06 |
Amgen Inc |
MOLECULAS QUIMERICAS DE ANTICUERPO RANKL-PTH/PTHrP
|
CN101506236B
(zh)
|
2005-11-30 |
2012-12-12 |
雅培制药有限公司 |
抗淀粉样β蛋白的单克隆抗体及其用途
|
BRPI0619249A2
(pt)
|
2005-11-30 |
2011-09-20 |
Abbott Lab |
anticorpos anti-globulÈmeros-aß, frações que se ligam a antìgeno destes, hibridomas correspondentes, ácidos nucléicos, vetores, células hospedeiras, métodos de produzir os ditos anticorpos, composições compreendendo os ditos anticorpos, usos dos ditos anticorpos e métodos de usar os ditos anticorpos
|
US20130172274A1
(en)
|
2005-12-20 |
2013-07-04 |
Duke University |
Methods and compositions for delivering active agents with enhanced pharmacological properties
|
US8334257B2
(en)
|
2005-12-20 |
2012-12-18 |
Duke University |
Methods and compositions for delivering active agents with enhanced pharmacological properties
|
US8841255B2
(en)
|
2005-12-20 |
2014-09-23 |
Duke University |
Therapeutic agents comprising fusions of vasoactive intestinal peptide and elastic peptides
|
CN101400703B
(zh)
|
2006-02-01 |
2013-05-08 |
赛法隆澳大利亚控股有限公司 |
结构域抗体构建体
|
TW200744634A
(en)
|
2006-02-21 |
2007-12-16 |
Wyeth Corp |
Methods of using antibodies against human IL-22
|
TWI417301B
(zh)
|
2006-02-21 |
2013-12-01 |
Wyeth Corp |
對抗人類介白素-22(il-22)之抗體及其用途
|
SG170837A1
(en)
|
2006-04-05 |
2011-05-30 |
Abbott Biotech Ltd |
Antibody purification
|
EP2666478A3
(en)
|
2006-04-10 |
2014-10-22 |
AbbVie Biotechnology Ltd |
Uses and compositions for treatment of psoriasis
|
US9399061B2
(en)
|
2006-04-10 |
2016-07-26 |
Abbvie Biotechnology Ltd |
Methods for determining efficacy of TNF-α inhibitors for treatment of rheumatoid arthritis
|
US20080118496A1
(en)
*
|
2006-04-10 |
2008-05-22 |
Medich John R |
Uses and compositions for treatment of juvenile rheumatoid arthritis
|
US9605064B2
(en)
*
|
2006-04-10 |
2017-03-28 |
Abbvie Biotechnology Ltd |
Methods and compositions for treatment of skin disorders
|
WO2007120626A2
(en)
|
2006-04-10 |
2007-10-25 |
Abbott Biotechnology Ltd. |
Uses and compositions for treatment of ankylosing spondylitis
|
US20090317399A1
(en)
*
|
2006-04-10 |
2009-12-24 |
Pollack Paul F |
Uses and compositions for treatment of CROHN'S disease
|
US9624295B2
(en)
|
2006-04-10 |
2017-04-18 |
Abbvie Biotechnology Ltd. |
Uses and compositions for treatment of psoriatic arthritis
|
CA2564435A1
(en)
|
2006-04-10 |
2007-10-10 |
Abbott Biotechnology Ltd. |
Methods for monitoring and treating intestinal disorders
|
US20080131374A1
(en)
*
|
2006-04-19 |
2008-06-05 |
Medich John R |
Uses and compositions for treatment of rheumatoid arthritis
|
US20080311043A1
(en)
*
|
2006-06-08 |
2008-12-18 |
Hoffman Rebecca S |
Uses and compositions for treatment of psoriatic arthritis
|
US20100021451A1
(en)
|
2006-06-08 |
2010-01-28 |
Wong Robert L |
Uses and compositions for treatment of ankylosing spondylitis
|
TWI527603B
(zh)
|
2006-06-30 |
2016-04-01 |
艾伯維生物技術有限責任公司 |
自動注射裝置
|
UA115964C2
(uk)
|
2006-09-08 |
2018-01-25 |
Еббві Айрленд Анлімітед Компані |
Інтерлейкін-13-зв'язувальний білок
|
EP2500415A1
(en)
|
2006-09-13 |
2012-09-19 |
Abbott Laboratories |
Cell culture improvements
|
AU2007294731B2
(en)
*
|
2006-09-13 |
2014-04-17 |
Abbvie Inc. |
Cell culture improvements
|
US8911964B2
(en)
|
2006-09-13 |
2014-12-16 |
Abbvie Inc. |
Fed-batch method of making human anti-TNF-alpha antibody
|
MX2009004351A
(es)
|
2006-10-27 |
2009-05-12 |
Abbott Biotech Ltd |
Anticuerpos anti-htnfalfa cristalinos.
|
US8754107B2
(en)
|
2006-11-17 |
2014-06-17 |
Abbvie Inc. |
Aminopyrrolidines as chemokine receptor antagonists
|
BRPI0719109A2
(pt)
|
2006-11-21 |
2013-12-10 |
Kalobios Pharmaceuticals Inc |
Métodos para tratar doenças inflamatórias crônicas usando um antagonista de gm-csf
|
US8455626B2
(en)
|
2006-11-30 |
2013-06-04 |
Abbott Laboratories |
Aβ conformer selective anti-aβ globulomer monoclonal antibodies
|
EP2114443A4
(en)
|
2006-12-29 |
2011-08-10 |
Abbott Lab |
IL-1A / IL-1B ANTIBODY WITH DOUBLE SPECIFICITY
|
US7776331B1
(en)
|
2007-01-16 |
2010-08-17 |
Abbott Laboratories |
Methods of treating plaque psoriasis
|
JP2008209378A
(ja)
*
|
2007-01-31 |
2008-09-11 |
Fujifilm Corp |
バイオセンサー基板
|
EP2979729A3
(en)
|
2007-02-05 |
2016-05-11 |
Apellis Pharmaceuticals, Inc. |
Compstatin analogues for use in the treatment of inflammatory conditions of the respiratory system
|
EP2486928A1
(en)
|
2007-02-27 |
2012-08-15 |
Abbott GmbH & Co. KG |
Method for the treatment of amyloidoses
|
CA2680564C
(en)
*
|
2007-03-12 |
2018-05-01 |
Esbatech Ag |
Sequence based engineering and optimization of single chain antibodies
|
CL2008000883A1
(es)
*
|
2007-03-28 |
2008-10-03 |
Wyeth6 3 |
Metodo de deteccion de compuestos capaces de antagonizar la senalizacion de il-17f/il-17a; compuesto identificado por dicho metodo; uso de una cantidad de un antagonista de senalizacion de il-17f/il-17a, composicion farmaceutica que comprende dicho a
|
US7807168B2
(en)
*
|
2007-04-10 |
2010-10-05 |
Vaccinex, Inc. |
Selection of human TNFα specific antibodies
|
WO2008124858A2
(en)
*
|
2007-04-11 |
2008-10-23 |
F-Star Biotechnologische Forschungs- Und Entwicklungsges. M.B.H. |
Targeted receptor
|
EP2165194A4
(en)
|
2007-05-31 |
2010-09-08 |
Abbott Lab |
BIOMARKERS FOR PREDICTING RESPONSABILITY TO TNF ALPHA INHIBITORS IN AUTOIMMUNE DISEASES
|
EP2152318A4
(en)
*
|
2007-06-01 |
2011-12-07 |
Abbott Biotech Ltd |
COMPOSITIONS AND USES FOR THE TREATMENT OF PSORIASIS AND CROHN'S DISEASE
|
MX2009013137A
(es)
*
|
2007-06-06 |
2010-04-30 |
Domantis Ltd |
Metodos para seleccionar polipeptidos resistentes a la proteasa.
|
MX2009012968A
(es)
*
|
2007-06-06 |
2010-04-01 |
Domantis Ltd |
Polipeptidos, dominios variables de anticuerpo y antagonistas.
|
EP2171451A4
(en)
|
2007-06-11 |
2011-12-07 |
Abbott Biotech Ltd |
METHOD FOR TREATING JUVENILIAN IDIOPATHIC ARTHRITIS
|
WO2008157356A2
(en)
|
2007-06-14 |
2008-12-24 |
Biogen Idec Ma Inc. |
Antibody formulations
|
DK2164961T3
(en)
*
|
2007-06-25 |
2015-03-02 |
Esbatech Alcon Biomed Res Unit |
Sequence based forward position and optimization of single chain antibodies
|
WO2009000099A2
(en)
*
|
2007-06-25 |
2008-12-31 |
Esbatech Ag |
Methods of modifying antibodies, and modified antibodies with improved functional properties
|
US20090110679A1
(en)
*
|
2007-07-13 |
2009-04-30 |
Luk-Chiu Li |
Methods and compositions for pulmonary administration of a TNFa inhibitor
|
SG183709A1
(en)
|
2007-08-08 |
2012-09-27 |
Abbott Lab |
Compositions and methods for crystallizing antibodies
|
CA3128656A1
(en)
|
2007-08-22 |
2009-02-26 |
The Regents Of The University Of California |
Activatable binding polypeptides and methods of identification and use thereof
|
WO2009032128A1
(en)
*
|
2007-08-28 |
2009-03-12 |
Abbott Biotechnology Ltd. |
Compositions and methods comprising binding proteins for adalimumab
|
JP2009082033A
(ja)
*
|
2007-09-28 |
2009-04-23 |
Kaneka Corp |
完全ヒト型抗体生産法
|
EP2205249B1
(en)
|
2007-09-28 |
2018-11-07 |
Intrexon Corporation |
Therapeutic gene-switch constructs and bioreactors for the expression of biotherapeutic molecules, and uses thereof
|
CA2706700A1
(en)
|
2007-11-08 |
2009-05-14 |
Cytimmune Sciences, Inc. |
Compositions and methods for generating antibodies
|
NZ709704A
(en)
|
2007-11-30 |
2017-03-31 |
Abbvie Biotechnology Ltd |
Protein formulations and methods of making same
|
US8883146B2
(en)
|
2007-11-30 |
2014-11-11 |
Abbvie Inc. |
Protein formulations and methods of making same
|
CN101965514A
(zh)
*
|
2008-01-03 |
2011-02-02 |
艾博特生物技术有限公司 |
预测化合物在治疗银屑病中的长期功效
|
SG2013054218A
(en)
|
2008-01-15 |
2014-10-30 |
Abbott Gmbh & Co Kg |
Powdered protein compositions and methods of making same
|
US8962803B2
(en)
|
2008-02-29 |
2015-02-24 |
AbbVie Deutschland GmbH & Co. KG |
Antibodies against the RGM A protein and uses thereof
|
WO2009121690A1
(en)
|
2008-03-13 |
2009-10-08 |
Biotest Ag |
Agent for treating disease
|
RU2540018C2
(ru)
|
2008-03-13 |
2015-01-27 |
Биотест Аг |
Средство для лечения заболевания
|
CN102027016A
(zh)
|
2008-03-13 |
2011-04-20 |
生物测试股份公司 |
一种治疗疾病的试剂
|
RU2497545C2
(ru)
|
2008-03-18 |
2013-11-10 |
Эбботт Лэборетриз |
Способ лечения псориаза (варианты)
|
US20100260668A1
(en)
*
|
2008-04-29 |
2010-10-14 |
Abbott Laboratories |
Dual Variable Domain Immunoglobulins and Uses Thereof
|
CA2722466A1
(en)
|
2008-04-29 |
2009-11-05 |
Tariq Ghayur |
Dual variable domain immunoglobulins and uses thereof
|
EP2113568A1
(en)
|
2008-04-30 |
2009-11-04 |
Deutsches Rheuma-Forschungszentrum Berlin |
Knock-in mouse for modelling blockade of human TNFalpha
|
KR101649189B1
(ko)
|
2008-05-09 |
2016-08-18 |
애브비 인코포레이티드 |
최종 당화 산물의 수용체(rage)에 대한 항체 및 이의 용도
|
WO2009142186A1
(ja)
*
|
2008-05-20 |
2009-11-26 |
株式会社カネカ |
細胞障害性組成物
|
AU2009256250B2
(en)
|
2008-06-03 |
2013-05-30 |
Abbvie Inc. |
Dual variable domain immunoglobulins and uses thereof
|
CA2725666A1
(en)
|
2008-06-03 |
2009-12-10 |
Abbott Laboratories |
Dual variable domain immunoglobulins and uses thereof
|
DK3241843T3
(da)
|
2008-06-25 |
2021-09-06 |
Novartis Ag |
Opløselighedsoptimering af immunbindere
|
KR20190133077A
(ko)
|
2008-06-25 |
2019-11-29 |
에스바테크 - 어 노바티스 컴파니 엘엘씨 |
TNFα를 저해하는 안정한 가용성 항체
|
CA3020290A1
(en)
|
2008-06-25 |
2009-12-30 |
Esbatech, An Alcon Biomedical Research Unit Llc |
Stable and soluble antibodies inhibiting vegf
|
EP3412300A1
(en)
|
2008-06-27 |
2018-12-12 |
Duke University |
Therapeutic agents comprising elastin-like peptides
|
MX2011000039A
(es)
*
|
2008-07-02 |
2011-05-31 |
Emergent Product Dev Seattle |
Proteinas antagonistas del factor-beta de crecimiento transformante (tgf-beta), que se unen a multiples objetivos.
|
RU2559525C2
(ru)
|
2008-07-08 |
2015-08-10 |
Эббви Инк |
Белки, связывающие простагландин е2, и их применение
|
NZ590074A
(en)
|
2008-07-08 |
2012-12-21 |
Abbott Lab |
Prostaglandin e2 dual variable domain immunoglobulins and uses thereof
|
US20110159011A1
(en)
*
|
2008-08-28 |
2011-06-30 |
Wyeth Llc |
Uses of il-22, il-17, and il-1 family cytokines in autoimmune diseases
|
EP2340039B1
(en)
*
|
2008-10-07 |
2015-11-25 |
National Cheng Kung University |
Use of il-20 antagonists for treating osteoporosis
|
WO2010056550A1
(en)
|
2008-10-29 |
2010-05-20 |
Wyeth Llc |
Methods for purification of single domain antigen binding molecules
|
CN102271707B
(zh)
|
2008-10-29 |
2015-04-08 |
阿布林克斯公司 |
单域抗原结合性分子的制剂
|
US8415291B2
(en)
|
2008-10-31 |
2013-04-09 |
Centocor Ortho Biotech Inc. |
Anti-TNF alpha fibronectin type III domain based scaffold compositions, methods and uses
|
CN101419224B
(zh)
*
|
2008-11-06 |
2012-08-22 |
复旦大学附属华山医院 |
一种同时测定人血浆中霉酚酸酯、霉酚酸及其代谢物的方法
|
CN102301235B
(zh)
*
|
2008-11-28 |
2014-11-19 |
Abbvie公司 |
稳定的抗体组合物和用于稳定其的方法
|
AU2009333489A1
(en)
|
2008-12-30 |
2010-07-08 |
Centocor Ortho Biotech Inc. |
Serum markers predicting clinical response to anti-TNF antibodies in patients with ankylosing spondylitis
|
CN101766602B
(zh)
*
|
2008-12-30 |
2012-01-11 |
中国医学科学院血液病医院(血液学研究所) |
取代芳香基腙类化合物在作为肿瘤坏死因子抑制剂药物方面的应用
|
EP2385955B1
(en)
|
2009-01-12 |
2020-08-12 |
CytomX Therapeutics, Inc. |
Modified antibody compositions, methods of making and using thereof
|
AU2010215761B2
(en)
|
2009-02-23 |
2017-04-06 |
Cytomx Therapeutics, Inc |
Proproteins and methods of use thereof
|
US8030026B2
(en)
|
2009-02-24 |
2011-10-04 |
Abbott Laboratories |
Antibodies to troponin I and methods of use thereof
|
NZ594514A
(en)
*
|
2009-03-05 |
2013-06-28 |
Abbott Lab |
Interleukin-17 BINDING PROTEINS
|
RU2595379C2
(ru)
|
2009-04-16 |
2016-08-27 |
АббВай Биотерапеутикс Инк. |
АНТИТЕЛА ПРОТИВ TNF-α И ИХ ПРИМЕНЕНИЯ
|
CN101875694B
(zh)
*
|
2009-04-28 |
2014-04-02 |
中国医学科学院基础医学研究所 |
TNFα的抗体及其用途
|
TWI583418B
(zh)
|
2009-04-29 |
2017-05-21 |
艾伯維生物技術有限責任公司 |
針筒柱塞及自動注射裝置
|
JP2012526121A
(ja)
*
|
2009-05-04 |
2012-10-25 |
アボツト・バイオテクノロジー・リミテツド |
ヒト抗tnfアルファ抗体の安定した高蛋白質濃度製剤
|
WO2010132872A1
(en)
*
|
2009-05-15 |
2010-11-18 |
Novimmune S.A |
Combination therapies and methods using anti-cd3 modulating agents and anti-tnf antagonists
|
UY32808A
(es)
*
|
2009-07-29 |
2011-02-28 |
Abbott Lab |
Inmunoglobulinas como dominio variable dual y usos de las mismas
|
EP2464370B1
(en)
*
|
2009-08-14 |
2017-03-29 |
Phasebio Pharmaceuticals, Inc. |
Modified vasoactive intestinal peptides
|
EP2467169A4
(en)
*
|
2009-08-21 |
2013-01-02 |
Gilead Biologics Inc |
IN VIVO SCREENING ASSAYS
|
TWI465250B
(zh)
|
2009-08-29 |
2014-12-21 |
Abbvie Inc |
治療用之dll4結合蛋白質
|
IN2012DN02737A
(xx)
|
2009-09-01 |
2015-09-11 |
Abbott Lab |
|
SG179135A1
(en)
*
|
2009-09-14 |
2012-05-30 |
Abbott Lab |
Methods for treating psoriasis
|
EP2480252A4
(en)
*
|
2009-09-24 |
2014-04-30 |
Xbiotech Inc |
METHOD, COMPOSITIONS AND KITS FOR REDUCING ANTIBODY REACTIONS
|
WO2011038301A2
(en)
|
2009-09-25 |
2011-03-31 |
Xoma Technology Ltd. |
Screening methods
|
KR20140015139A
(ko)
|
2009-10-15 |
2014-02-06 |
애브비 인코포레이티드 |
이원 가변 도메인 면역글로불린 및 이의 용도
|
RU2571489C2
(ru)
*
|
2009-10-26 |
2015-12-20 |
Нестек С.А. |
Способы выявления препаратов и аутоантител против tnf
|
UY32979A
(es)
*
|
2009-10-28 |
2011-02-28 |
Abbott Lab |
Inmunoglobulinas con dominio variable dual y usos de las mismas
|
CN102812040A
(zh)
*
|
2009-10-30 |
2012-12-05 |
雅培制药有限公司 |
Sorf构建体和多基因表达
|
US8420083B2
(en)
|
2009-10-31 |
2013-04-16 |
Abbvie Inc. |
Antibodies to receptor for advanced glycation end products (RAGE) and uses thereof
|
WO2011058087A1
(en)
|
2009-11-11 |
2011-05-19 |
Gentian As |
Immunoassay for assessing related analytes of different origin
|
GB0920944D0
(en)
|
2009-11-30 |
2010-01-13 |
Biotest Ag |
Agents for treating disease
|
US8871208B2
(en)
*
|
2009-12-04 |
2014-10-28 |
Abbvie Inc. |
11-β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitors and uses thereof
|
CN102656190A
(zh)
|
2009-12-08 |
2012-09-05 |
雅培股份有限两合公司 |
用于在视网膜神经纤维层变性治疗中使用的针对rgm a蛋白质的单克隆抗体
|
TWI619521B
(zh)
|
2009-12-15 |
2018-04-01 |
艾伯維生物技術有限責任公司 |
自動注射裝置、自動注射方法及防止不發射情況之方法
|
AU2010330907A1
(en)
|
2009-12-16 |
2012-06-14 |
Bosch, Phillip |
Methods of treating interstitial cystitis
|
USRE49251E1
(en)
|
2010-01-04 |
2022-10-18 |
Mapi Pharma Ltd. |
Depot systems comprising glatiramer or pharmacologically acceptable salt thereof
|
WO2011092715A2
(en)
*
|
2010-01-27 |
2011-08-04 |
Tata Memorial Centre |
Method for in-vivo binding of chromatin fragments
|
JP2013518590A
(ja)
|
2010-02-02 |
2013-05-23 |
アボツト・バイオテクノロジー・リミテツド |
TNF−α阻害剤を用いる処置に対する応答性を予測するための方法および組成物
|
CN102167741B
(zh)
*
|
2010-02-25 |
2014-05-14 |
上海百迈博制药有限公司 |
一种全人源抗TNF-α单克隆抗体、其制备方法及用途
|
EP2542582A4
(en)
|
2010-03-02 |
2013-12-04 |
Abbvie Inc |
THERAPEUTIC PROTEINS LINKING TO DLL4
|
KR20150038556A
(ko)
|
2010-04-07 |
2015-04-08 |
애브비 인코포레이티드 |
TNF-α 결합 단백질
|
MX360403B
(es)
|
2010-04-15 |
2018-10-31 |
Abbvie Inc |
Proteinas de union a amiloide beta.
|
PT3202789T
(pt)
|
2010-04-16 |
2020-06-16 |
Biogen Ma Inc |
Anticorpos anti-vla-4
|
JP5809242B2
(ja)
|
2010-04-21 |
2015-11-10 |
アッヴィ バイオテクノロジー リミテッド |
治療薬の制御送達のための装着型自動注入装置
|
EP2571532B1
(en)
|
2010-05-14 |
2017-05-03 |
Abbvie Inc. |
Il-1 binding proteins
|
WO2011146727A1
(en)
|
2010-05-19 |
2011-11-24 |
Philip Bosch |
Methods of treating interstitial cystitis
|
SI2575884T1
(sl)
|
2010-06-03 |
2018-10-30 |
Abbvie Biotechnology Ltd |
Uporabe in sestavki za zdravljenje supurativnega hidradenitisa (HS)
|
WO2012006500A2
(en)
|
2010-07-08 |
2012-01-12 |
Abbott Laboratories |
Monoclonal antibodies against hepatitis c virus core protein
|
UY33492A
(es)
|
2010-07-09 |
2012-01-31 |
Abbott Lab |
Inmunoglobulinas con dominio variable dual y usos de las mismas
|
US20120100166A1
(en)
|
2010-07-15 |
2012-04-26 |
Zyngenia, Inc. |
Ang-2 Binding Complexes and Uses Thereof
|
CA2807014A1
(en)
|
2010-08-03 |
2012-02-09 |
Abbvie Inc. |
Dual variable domain immunoglobulins and uses thereof
|
JP6147665B2
(ja)
|
2010-08-14 |
2017-06-14 |
アッヴィ・インコーポレイテッド |
アミロイドベータ結合タンパク質
|
RS63063B1
(sr)
|
2010-08-19 |
2022-04-29 |
Zoetis Belgium S A |
Anti-ngf antitela i njihova upotreba
|
TW201211252A
(en)
|
2010-08-26 |
2012-03-16 |
Abbott Lab |
Dual variable domain immunoglobulins and uses thereof
|
UY33679A
(es)
|
2010-10-22 |
2012-03-30 |
Esbatech |
Anticuerpos estables y solubles
|
UA113500C2
(xx)
|
2010-10-29 |
2017-02-10 |
|
Одержані екструзією розплаву тверді дисперсії, що містять індукуючий апоптоз засіб
|
EP2632436B1
(en)
|
2010-10-29 |
2018-08-29 |
Abbvie Inc. |
Solid dispersions containing an apoptosis-inducing agent
|
CN103492583A
(zh)
*
|
2010-11-02 |
2014-01-01 |
Abbvie公司 |
双重可变结构域免疫球蛋白及其用途
|
MX344727B
(es)
|
2010-11-11 |
2017-01-05 |
Abbvie Biotechnology Ltd |
Formulaciones liquidas de anticuerpos anti-tnf-alfa de alta concentracion mejoradas.
|
US8722657B2
(en)
|
2010-11-23 |
2014-05-13 |
Abbvie Inc. |
Salts and crystalline forms of an apoptosis-inducing agent
|
WO2012071374A1
(en)
|
2010-11-23 |
2012-05-31 |
Abbott Laboratories |
Methods of treatment using selective bcl-2 inhibitors
|
AR084210A1
(es)
*
|
2010-12-08 |
2013-05-02 |
Abbott Lab |
PROTEINAS DE UNION AL TNF-a
|
RU2627171C2
(ru)
|
2010-12-21 |
2017-08-03 |
Эббви Инк. |
Il-1 альфа и бета биспецифические иммуноглобулины с двойными вариабельными доменами и их применение
|
TW201307388A
(zh)
|
2010-12-21 |
2013-02-16 |
Abbott Lab |
Il-1結合蛋白
|
EP2490024A1
(en)
|
2010-12-22 |
2012-08-22 |
Proteomika, S.L. |
Method to optimize the treatment of patients with biological drugs
|
PE20141436A1
(es)
|
2011-01-24 |
2014-11-15 |
Abbvie Biotechnology Ltd |
Dispositivos de inyeccion automatica con superficies de agarre sobremoldeadas
|
WO2012101629A1
(en)
|
2011-01-24 |
2012-08-02 |
Elcam Medical Agricultural Cooperative Association Ltd. |
Injector
|
KR101989342B1
(ko)
|
2011-01-24 |
2019-06-14 |
애브비 바이오테크놀로지 리미티드 |
주사기로부터 니들 실드의 제거 및 자동 주사 디바이스들
|
RU2455025C1
(ru)
*
|
2011-02-10 |
2012-07-10 |
Федеральное государственное автономное образовательное учреждение высшего профессионального образования "Белгородский государственный национальный исследовательский университет" (НИУ "БелГУ") |
Способ фармакологической коррекции ишемии конечности смесью растворов гомеопатических разведений
|
US20130344081A1
(en)
|
2011-03-07 |
2013-12-26 |
The University Of Tokushima |
Method of treating amyotrophic lateral sclerosis
|
EP2686036A1
(en)
|
2011-03-18 |
2014-01-22 |
AbbVie Inc. |
Systems, devices and methods for assembling automatic injection devices and sub-assemblies thereof
|
TWI743461B
(zh)
|
2011-03-28 |
2021-10-21 |
法商賽諾菲公司 |
具有交叉結合區定向之雙重可變區類抗體結合蛋白
|
AU2012236405B2
(en)
|
2011-03-29 |
2015-07-30 |
Abbvie Inc. |
Improved shroud deployment in automatic injection devices
|
ES2605817T3
(es)
|
2011-04-21 |
2017-03-16 |
Abbvie Inc. |
Dispositivo de inyección automático portátil
|
WO2012149197A2
(en)
|
2011-04-27 |
2012-11-01 |
Abbott Laboratories |
Methods for controlling the galactosylation profile of recombinantly-expressed proteins
|
CN103857699B
(zh)
|
2011-05-24 |
2016-08-31 |
泽恩格尼亚股份有限公司 |
多价和单价多特异性复合物及其用途
|
CN103635803A
(zh)
|
2011-05-31 |
2014-03-12 |
比奥根艾迪克Ma公司 |
评估进行性多灶性白质脑病风险的方法
|
CA2873553C
(en)
|
2011-06-06 |
2020-01-28 |
Phasebio Pharmaceuticals, Inc. |
Use of modified vasoactive intestinal peptides in the treatment of hypertension
|
SG10201505454SA
(en)
|
2011-07-13 |
2015-09-29 |
Abbvie Inc |
Methods and compositions for treating asthma using anti-il-13 antibodies
|
GB201112429D0
(en)
*
|
2011-07-19 |
2011-08-31 |
Glaxo Group Ltd |
Antigen-binding proteins with increased FcRn binding
|
JP2014527957A
(ja)
*
|
2011-08-01 |
2014-10-23 |
アヴァクシア バイオロジクス,インコーポレーテッド |
ヒトtnfに特異的なウシポリクローナル抗体
|
CA2850572A1
(en)
*
|
2011-10-20 |
2013-04-25 |
Esbatech, A Novartis Company Llc |
Stable multiple antigen-binding antibody
|
RU2014120981A
(ru)
|
2011-10-24 |
2015-12-10 |
Эббви Инк. |
Иммунные связывающие агенты против склеростина
|
KR20140084253A
(ko)
*
|
2011-10-24 |
2014-07-04 |
애브비 인코포레이티드 |
Tnf에 대한 면역결합제
|
MX2014004980A
(es)
|
2011-10-24 |
2014-09-11 |
Abbvie Inc |
Inmunoaglutinantes biespecificos dirigidos contra tnf e il-17.
|
WO2013080050A2
(en)
|
2011-11-30 |
2013-06-06 |
Universitaetsklinikum Erlangen |
Methods and compositions for determining responsiveness to treatment with a tnf-alpha inhibitor
|
US9636398B2
(en)
|
2011-12-14 |
2017-05-02 |
AbbVie Deutschland GmbH & Co. KG |
Composition and method for the diagnosis and treatment of iron-related disorders
|
EP2791173B1
(en)
|
2011-12-14 |
2020-07-29 |
AbbVie Deutschland GmbH & Co. KG |
Composition and method for the diagnosis and treatment of iron-related disorders
|
US9580501B2
(en)
|
2011-12-16 |
2017-02-28 |
Synthon Biopharmaceuticals B.V. |
Anti-TNF alpha monoclonal secretory IgA antibodies and methods for treating inflammatory diseases
|
UY34558A
(es)
|
2011-12-30 |
2013-07-31 |
Abbvie Inc |
Proteínas de unión específicas duales dirigidas contra il-13 y/o il-17
|
EP2915818A3
(en)
|
2011-12-30 |
2015-11-11 |
AbbVie Inc. |
Dual variable domain immunoglobulins and uses thereof
|
IL305223A
(en)
|
2012-01-27 |
2023-10-01 |
Abbvie Inc |
The composition and method for the diagnosis and treatment of diseases related to the degeneration of nerve cells
|
SG11201405475UA
(en)
|
2012-03-07 |
2014-10-30 |
Cadila Healthcare Ltd |
Pharmaceutical formulations of tnf-alpha antibodies
|
US9334319B2
(en)
|
2012-04-20 |
2016-05-10 |
Abbvie Inc. |
Low acidic species compositions
|
WO2013158273A1
(en)
|
2012-04-20 |
2013-10-24 |
Abbvie Inc. |
Methods to modulate c-terminal lysine variant distribution
|
US9067990B2
(en)
|
2013-03-14 |
2015-06-30 |
Abbvie, Inc. |
Protein purification using displacement chromatography
|
EP2657334B1
(en)
|
2012-04-26 |
2016-07-06 |
GeneFrontier Corporation |
Efficient method for displaying protein multimer
|
WO2013176754A1
(en)
|
2012-05-24 |
2013-11-28 |
Abbvie Inc. |
Novel purification of antibodies using hydrophobic interaction chromatography
|
US9617334B2
(en)
|
2012-06-06 |
2017-04-11 |
Zoetis Services Llc |
Caninized anti-NGF antibodies and methods thereof
|
AU2013270684B2
(en)
|
2012-06-08 |
2018-04-19 |
Sutro Biopharma, Inc. |
Antibodies comprising site-specific non-natural amino acid residues, methods of their preparation and methods of their use
|
UY34905A
(es)
|
2012-07-12 |
2014-01-31 |
Abbvie Inc |
Proteínas de unión a il-1
|
EP4074728A1
(en)
|
2012-08-31 |
2022-10-19 |
Sutro Biopharma, Inc. |
Modified peptides comprising an azido group
|
US9512214B2
(en)
|
2012-09-02 |
2016-12-06 |
Abbvie, Inc. |
Methods to control protein heterogeneity
|
KR20150043523A
(ko)
|
2012-09-02 |
2015-04-22 |
애브비 인코포레이티드 |
단백질 불균일성의 제어 방법
|
PE20191815A1
(es)
|
2012-09-07 |
2019-12-27 |
Coherus Biosciences Inc |
Formulaciones acuosas estables de adalimumab
|
SG11201502094TA
(en)
*
|
2012-09-19 |
2015-04-29 |
Abbvie Biotherapeutics Inc |
Methods for identifying antibodies with reduced immunogenicity
|
SG11201503324WA
(en)
|
2012-11-01 |
2015-05-28 |
Abbvie Inc |
Stable dual variable domain immunoglobulin protein formulations
|
AU2013337775B2
(en)
|
2012-11-01 |
2017-03-30 |
Abbvie Inc. |
Anti-VEGF/DLL4 dual variable domain immunoglobulins and uses thereof
|
TW202206465A
(zh)
|
2012-11-14 |
2022-02-16 |
美商再生元醫藥公司 |
重組細胞表面捕捉蛋白質
|
US9550986B2
(en)
|
2012-12-21 |
2017-01-24 |
Abbvie Inc. |
High-throughput antibody humanization
|
EP2938634A2
(en)
|
2012-12-28 |
2015-11-04 |
AbbVie Inc. |
Dual specific binding proteins having a receptor sequence
|
US9856319B2
(en)
|
2012-12-28 |
2018-01-02 |
Abbvie Inc. |
Monovalent binding proteins
|
AU2014215639B2
(en)
|
2013-01-25 |
2017-03-23 |
Thymon, Llc |
Compositions for selective reduction of circulating bioactive soluble TNF and methods for treating TNF-mediated disease
|
MX2015010427A
(es)
*
|
2013-02-13 |
2016-03-17 |
Lab Francais Du Fractionnement |
Anticuerpos anti-tnf-alfa altamente galactosilados y sus usos.
|
SG11201507230PA
(en)
|
2013-03-12 |
2015-10-29 |
Abbvie Inc |
Human antibodies that bind human tnf-alpha and methods of preparing the same
|
CA2899449A1
(en)
|
2013-03-14 |
2014-10-02 |
Abbvie Inc. |
Low acidic species compositions and methods for producing the same using displacement chromatography
|
WO2014159579A1
(en)
*
|
2013-03-14 |
2014-10-02 |
Abbvie Inc. |
MUTATED ANTI-TNFα ANTIBODIES AND METHODS OF THEIR USE
|
US20140275082A1
(en)
|
2013-03-14 |
2014-09-18 |
Abbvie Inc. |
Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases
|
US9017687B1
(en)
|
2013-10-18 |
2015-04-28 |
Abbvie, Inc. |
Low acidic species compositions and methods for producing and using the same using displacement chromatography
|
EP3916103A1
(en)
|
2013-03-14 |
2021-12-01 |
Abbott Laboratories |
Hcv core lipid binding domain monoclonal antibodies
|
WO2014151878A2
(en)
|
2013-03-14 |
2014-09-25 |
Abbvie Inc. |
Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using monosaccharides and oligosacharides
|
BR112015023355A8
(pt)
|
2013-03-14 |
2018-01-30 |
Abbott Lab |
antígenos recombinantes ns3 de hcv e mutantes dos mesmos para detecção de anticorpos aprimorada.
|
CA2906421C
(en)
|
2013-03-14 |
2022-08-16 |
George J. Dawson |
Hcv antigen-antibody combination assay and methods and compositions for use therein
|
WO2014158231A1
(en)
|
2013-03-14 |
2014-10-02 |
Abbvie Inc. |
Low acidic species compositions and methods for producing and using the same
|
CA2907181C
(en)
|
2013-03-15 |
2023-10-17 |
Viktor Roschke |
Multivalent and monovalent multispecific complexes and their uses
|
CN105324396A
(zh)
|
2013-03-15 |
2016-02-10 |
艾伯维公司 |
针对IL-1β和/或IL-17的双重特异性结合蛋白
|
US9469686B2
(en)
|
2013-03-15 |
2016-10-18 |
Abbott Laboratories |
Anti-GP73 monoclonal antibodies and methods of obtaining the same
|
EP2970457A2
(en)
|
2013-03-15 |
2016-01-20 |
AbbVie Inc. |
Dual specific binding proteins directed against tnf
|
BR112015029224A2
(pt)
*
|
2013-05-22 |
2017-09-19 |
Metabolic Eng Laboratories Co Ltd |
Anticorpo de alvo duplo tnf-alfa/cxcl10, transformante, método de produção de um anticorpo de alvo duplo tnf-alfa/cxcl10, composição farmacêutica e método de prevenção ou tratamento de uma doença imunológica
|
US10183988B2
(en)
|
2013-06-07 |
2019-01-22 |
Duke University |
Anti-Complement factor H antibodies
|
ES2865473T3
(es)
|
2013-07-10 |
2021-10-15 |
Sutro Biopharma Inc |
Anticuerpos que comprenden múltiples residuos de aminoácidos no naturales sitio-específicos, métodos para su preparación y métodos de uso
|
WO2015017683A1
(en)
*
|
2013-07-31 |
2015-02-05 |
Malast Mary |
Antimicrobial compositions and methods of use
|
RU2016107435A
(ru)
|
2013-09-13 |
2017-10-18 |
Дженентек, Инк. |
Композиции и способы обнаружения и количественного определения белка клеток-хозяев в клеточных линиях и рекомбинантные полипептидные продукты
|
WO2015038888A1
(en)
|
2013-09-13 |
2015-03-19 |
Genentech, Inc. |
Methods and compositions comprising purified recombinant polypeptides
|
US9598667B2
(en)
|
2013-10-04 |
2017-03-21 |
Abbvie Inc. |
Use of metal ions for modulation of protein glycosylation profiles of recombinant proteins
|
US20150125397A1
(en)
|
2013-10-06 |
2015-05-07 |
Abbvie Inc. |
Dual specific binding proteins directed against immune cell receptors and autoantigens
|
WO2015054658A1
(en)
|
2013-10-11 |
2015-04-16 |
Sutro Biopharma, Inc. |
Modified amino acids comprising tetrazine functional groups, methods of preparation, and methods of their use
|
AU2014337263B2
(en)
|
2013-10-16 |
2019-12-12 |
Outlook Therapeutics, Inc. |
Buffer formulations for enhanced antibody stability
|
US8946395B1
(en)
|
2013-10-18 |
2015-02-03 |
Abbvie Inc. |
Purification of proteins using hydrophobic interaction chromatography
|
US9085618B2
(en)
|
2013-10-18 |
2015-07-21 |
Abbvie, Inc. |
Low acidic species compositions and methods for producing and using the same
|
US9181337B2
(en)
|
2013-10-18 |
2015-11-10 |
Abbvie, Inc. |
Modulated lysine variant species compositions and methods for producing and using the same
|
WO2015073884A2
(en)
|
2013-11-15 |
2015-05-21 |
Abbvie, Inc. |
Glycoengineered binding protein compositions
|
WO2015084883A2
(en)
|
2013-12-02 |
2015-06-11 |
Abbvie, Inc. |
Compositions and methods for treating osteoarthritis
|
CN103965357B
(zh)
|
2013-12-31 |
2016-08-17 |
嘉和生物药业有限公司 |
一种抗人rankl抗体
|
EP3110976B1
(en)
|
2014-02-27 |
2020-05-13 |
Biogen MA Inc. |
Method of assessing risk of pml
|
WO2015135884A1
(en)
|
2014-03-10 |
2015-09-17 |
Richter Gedeon Nyrt. |
Immunoglobulin purification using pre-cleaning steps
|
AR099625A1
(es)
*
|
2014-03-21 |
2016-08-03 |
Lilly Co Eli |
Anticuerpos de il-21
|
AR099812A1
(es)
|
2014-03-21 |
2016-08-17 |
Abbvie Inc |
Anticuerpos y conjugados de anticuerpo y fármaco anti-egfr
|
IN2014MU01248A
(xx)
*
|
2014-04-02 |
2015-10-09 |
Intas Pharmaceuticals Ltd |
|
ES2818824T3
(es)
|
2014-05-08 |
2021-04-14 |
Phasebio Pharmaceuticals Inc |
Composiciones que comprenden una proteína de fusión de VIP-ELP para su uso en el tratamiento de fibrosis quística
|
EP2946765B1
(en)
|
2014-05-23 |
2016-08-31 |
Ares Trading S.A. |
Liquid pharmaceutical composition
|
ES2607489T3
(es)
|
2014-05-23 |
2017-03-31 |
Ares Trading S.A. |
Composición farmacéutica líquida
|
EP2946766B1
(en)
|
2014-05-23 |
2016-03-02 |
Ares Trading S.A. |
Liquid pharmaceutical composition
|
FR3022462B1
(fr)
*
|
2014-06-18 |
2018-04-27 |
Laboratoire Francais Du Fractionnement Et Des Biotechnologies |
Composition orale d'anticorps anti-tnfalpha
|
EP3145951A1
(en)
|
2014-06-24 |
2017-03-29 |
InSight Biopharmaceuticals Ltd. |
Methods of purifying antibodies
|
AU2015283270B9
(en)
*
|
2014-06-30 |
2021-04-01 |
Merck Patent Gmbh |
Anti-TNFa antibodies with pH-dependent antigen binding
|
WO2016004197A1
(en)
|
2014-07-03 |
2016-01-07 |
Abbvie Inc. |
Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using cobalt
|
WO2016007764A1
(en)
|
2014-07-09 |
2016-01-14 |
Abbvie Inc. |
Methods for modulating the glycosylation profile of recombinant proteins using non-commonly used sugars
|
TWI711629B
(zh)
*
|
2014-09-03 |
2020-12-01 |
德商包林格因蓋爾漢國際股份有限公司 |
靶向IL-23A與TNF-α之化合物及其用途
|
US10435464B1
(en)
|
2014-09-05 |
2019-10-08 |
Coherus Biosciences, Inc. |
Methods for making recombinant proteins
|
HUP1400510A1
(hu)
|
2014-10-28 |
2016-05-30 |
Richter Gedeon Nyrt |
Gyógyászati TNFalfa ellenes antitest készítmény
|
US10093733B2
(en)
|
2014-12-11 |
2018-10-09 |
Abbvie Inc. |
LRP-8 binding dual variable domain immunoglobulin proteins
|
EP3237000A1
(en)
|
2014-12-23 |
2017-11-01 |
Pfizer Inc |
Stable aqueous antibody formulation for anti tnf alpha antibodies
|
EP3085709B1
(en)
|
2014-12-28 |
2019-08-21 |
Genor Biopharma Co., Ltd |
Humanized anti-human rankl antibody, pharmaceutical composition and use thereof
|
EP3247718B1
(en)
|
2015-01-21 |
2021-09-01 |
Outlook Therapeutics, Inc. |
Modulation of charge variants in a monoclonal antibody composition
|
EP3053572A1
(en)
|
2015-02-06 |
2016-08-10 |
Ares Trading S.A. |
Liquid pharmaceutical composition
|
CA2976038A1
(en)
|
2015-02-09 |
2016-08-18 |
Phasebio Pharmaceuticals, Inc. |
Methods and compositions for treating muscle disease and disorders
|
CN105777905B
(zh)
*
|
2015-03-24 |
2019-06-25 |
广东东阳光药业有限公司 |
一种全人源抗TNF-α单克隆抗体及其应用
|
EP3078675A1
(en)
|
2015-04-10 |
2016-10-12 |
Ares Trading S.A. |
Induction dosing regimen for the treatment of tnf alpha mediated disorders
|
WO2016179469A1
(en)
*
|
2015-05-07 |
2016-11-10 |
Abbvie Inc. |
Methods and compositions for diagnosing and treating inflammatory bowel disease
|
CA2987051A1
(en)
|
2015-05-29 |
2016-12-08 |
Abbvie Inc. |
Anti-cd40 antibodies and uses thereof
|
TW201710286A
(zh)
|
2015-06-15 |
2017-03-16 |
艾伯維有限公司 |
抗vegf、pdgf及/或其受體之結合蛋白
|
HU231463B1
(hu)
|
2015-08-04 |
2024-01-28 |
Richter Gedeon Nyrt. |
Módszer rekombináns proteinek galaktóz tartalmának növelésére
|
US11229702B1
(en)
|
2015-10-28 |
2022-01-25 |
Coherus Biosciences, Inc. |
High concentration formulations of adalimumab
|
US11583584B1
(en)
|
2015-10-28 |
2023-02-21 |
Coherus Biosciences, Inc. |
Stable protein compositions and methods of their use
|
GB201522394D0
(en)
|
2015-12-18 |
2016-02-03 |
Ucb Biopharma Sprl |
Antibodies
|
EP3411401A1
(en)
|
2016-02-03 |
2018-12-12 |
Oncobiologics, Inc. |
Buffer formulations for enhanced antibody stability
|
US10465003B2
(en)
|
2016-02-05 |
2019-11-05 |
Janssen Biotech, Inc. |
Anti-TNF antibodies, compositions, methods and use for the treatment or prevention of type 1 diabetes
|
SI3219726T1
(sl)
*
|
2016-03-17 |
2021-02-26 |
Tillotts Pharma Ag |
Anti-TNF alfa protitelesa in njihovi funkcionalni fragmenti
|
EP3430044A1
(en)
*
|
2016-03-17 |
2019-01-23 |
Numab Innovation AG |
Anti-tnf alpha -antibodies and functional fragments thereof
|
WO2017177179A1
(en)
|
2016-04-08 |
2017-10-12 |
Gilead Sciences, Inc. |
Compositions and methods for treating cancer, inflammatory diseases and autoimmune diseases
|
US11071782B2
(en)
|
2016-04-20 |
2021-07-27 |
Coherus Biosciences, Inc. |
Method of filling a container with no headspace
|
WO2017189805A1
(en)
|
2016-04-27 |
2017-11-02 |
Abbvie Inc. |
Methods of treatment of diseases in which il-13 activity is detrimental using anti-il-13 antibodies
|
CR20180594A
(es)
|
2016-06-02 |
2019-07-29 |
Abbvie Inc |
Agonista del receptor de glucocorticoides e inmunoconjugados del mismo
|
MX2018015285A
(es)
|
2016-06-08 |
2019-09-18 |
Abbvie Inc |
Anticuerpos anti-b7-h3 y conjugados de anticuerpo y farmaco.
|
AU2017277534A1
(en)
|
2016-06-08 |
2019-01-03 |
Abbvie Inc. |
Anti-EGFR antibody drug conjugates
|
JP2019524651A
(ja)
|
2016-06-08 |
2019-09-05 |
アッヴィ・インコーポレイテッド |
抗cd98抗体及び抗体薬物コンジュゲート
|
US20200002421A1
(en)
|
2016-06-08 |
2020-01-02 |
Abbvie Inc. |
Anti-b7-h3 antibodies and antibody drug conjugates
|
EP3468615A1
(en)
|
2016-06-08 |
2019-04-17 |
AbbVie Inc. |
Anti-egfr antibody drug conjugates
|
EP3835322A3
(en)
|
2016-06-08 |
2021-10-06 |
AbbVie Inc. |
Anti-b7-h3 antibodies and antibody drug conjugates
|
WO2017218698A1
(en)
|
2016-06-15 |
2017-12-21 |
Sutro Biopharma, Inc. |
Antibodies with engineered ch2 domains, compositions thereof and methods of using the same
|
WO2018018613A1
(zh)
|
2016-07-29 |
2018-02-01 |
广东东阳光药业有限公司 |
一种提高抗体纯度的细胞培养基和培养方法
|
US10751324B2
(en)
|
2016-09-02 |
2020-08-25 |
The University Of Chicago |
Treatment of TNF- alpha cytotoxicity
|
WO2018050902A2
(en)
*
|
2016-09-15 |
2018-03-22 |
Quadrucept Bio Limited |
Multimers, tetramers & octamers
|
BR112019006710A2
(pt)
|
2016-10-03 |
2019-06-25 |
Abbott Lab |
métodos aprimorados para avaliação do estado da uch-l1 em amostras de pacientes
|
WO2018075408A1
(en)
|
2016-10-17 |
2018-04-26 |
Alexion Pharmaceuticals, Inc. |
Methods of treating acute myeloid leukemia (aml) with combinations of anti-cd200 antibodies, cytarabine, and daunorubicin
|
BR112019007858A2
(pt)
|
2016-10-21 |
2019-07-02 |
Amgen Inc |
formulações farmacêuticas e métodos para produzir as mesmas
|
WO2018102594A1
(en)
|
2016-12-01 |
2018-06-07 |
Alexion Pharmaceuticals, Inc. |
Methods of treating solid tumors with anti-cd200 antibodies
|
WO2018106959A1
(en)
|
2016-12-07 |
2018-06-14 |
Progenity Inc. |
Gastrointestinal tract detection methods, devices and systems
|
US20190343425A1
(en)
|
2016-12-14 |
2019-11-14 |
Progenity, Inc. |
Treatment of a disease of the gastrointestinal tract with a tnf inhibitor
|
MA50134A
(fr)
|
2016-12-16 |
2020-07-29 |
Bluefin Biomedicine Inc |
Anticorps anti-protéine 1 contenant un domaine anti-cub (cdcp1), conjugués anticorps-médicament et leurs méthodes d'utilisation
|
JOP20190162A1
(ar)
|
2016-12-30 |
2019-06-27 |
Biocad Joint Stock Co |
تركيبة صيدلانية مائية من جسم مضاد لـ tnf? أحادي النسيلة معاود الارتباط الجيني
|
WO2018131893A1
(ko)
|
2017-01-11 |
2018-07-19 |
㈜셀트리온 |
안정한 액체 제제
|
TWI788321B
(zh)
|
2017-01-20 |
2023-01-01 |
美商健臻公司 |
骨靶向抗體
|
TWI787230B
(zh)
|
2017-01-20 |
2022-12-21 |
法商賽諾菲公司 |
抗TGF-β抗體及其用途
|
CN110234351A
(zh)
|
2017-01-30 |
2019-09-13 |
詹森生物科技公司 |
用于治疗活动性银屑病关节炎的抗tnf抗体、组合物和方法
|
CN110418652A
(zh)
|
2017-02-07 |
2019-11-05 |
詹森生物科技公司 |
用于治疗活动性强直性脊柱炎的抗tnf抗体、组合物和方法
|
US11608357B2
(en)
|
2018-08-28 |
2023-03-21 |
Arecor Limited |
Stabilized antibody protein solutions
|
EP3372242A1
(en)
|
2017-03-06 |
2018-09-12 |
Ares Trading S.A. |
Liquid pharmaceutical composition
|
EP3372241A1
(en)
|
2017-03-06 |
2018-09-12 |
Ares Trading S.A. |
Liquid pharmaceutical composition
|
US11016092B2
(en)
|
2017-03-23 |
2021-05-25 |
Abbott Laboratories |
Methods for aiding in the diagnosis and determination of the extent of traumatic brain injury in a human subject using the early biomarker ubiquitin carboxy-terminal hydrolase L1
|
US11167003B2
(en)
|
2017-03-26 |
2021-11-09 |
Mapi Pharma Ltd. |
Methods for suppressing or alleviating primary or secondary progressive multiple sclerosis (PPMS or SPMS) using sustained release glatiramer depot systems
|
WO2018184692A1
(en)
|
2017-04-07 |
2018-10-11 |
Ares Trading S.A. |
Liquid pharmaceutical composition
|
WO2018191531A1
(en)
|
2017-04-15 |
2018-10-18 |
Abbott Laboratories |
Methods for aiding in the hyperacute diagnosis and determination of traumatic brain injury in a human subject using early biomarkers
|
US10865238B1
(en)
|
2017-05-05 |
2020-12-15 |
Duke University |
Complement factor H antibodies
|
CA3078725A1
(en)
|
2017-05-25 |
2018-11-29 |
Abbott Laboratories |
Methods for aiding in the determination of whether to perform imaging on a human subject who has sustained or may have sustained an injury to the head using early biomarkers
|
BR112019025313A2
(pt)
|
2017-05-30 |
2020-06-23 |
Abbott Laboratories |
Métodos para auxílio no diagnóstico e avaliação de uma lesão cerebral traumática leve em um indivíduo humano usando troponina cardíaca i
|
EP3649474A1
(en)
|
2017-07-03 |
2020-05-13 |
Abbott Laboratories |
Improved methods for measuring ubiquitin carboxy-terminal hydrolase l1 levels in blood
|
US11761963B2
(en)
|
2017-09-27 |
2023-09-19 |
Alexion Pharmaceuticals, Inc. |
Biomarker signature for predicting tumor response to anti-CD200 therapy
|
RU2020117698A
(ru)
|
2017-12-01 |
2022-01-04 |
Эббви Инк. |
Агонист глюкокортикоидного рецептора и его иммуноконъюгаты
|
CN109879962B
(zh)
*
|
2017-12-06 |
2022-10-11 |
北京科立思维生物科技有限公司 |
抗tnf单链抗体、抗il-6单链抗体及其融合蛋白及其应用
|
EP3721233A2
(en)
|
2017-12-09 |
2020-10-14 |
Abbott Laboratories |
Methods for aiding in the diagnosis and evaluation of a subject who has sustained an orthopedic injury and that has or may have sustained an injury to the head, such as mild traumatic brain injury (tbi), using glial fibrillary acidic protein (gfap) and/or ubiquitin carboxy-terminal hydrolase l1 (uch-l1)
|
US11016105B2
(en)
|
2017-12-09 |
2021-05-25 |
Abbott Laboratories |
Methods for aiding in diagnosing and evaluating a traumatic brain injury in a human subject using a combination of GFAP and UCH-L1
|
WO2019126536A1
(en)
|
2017-12-20 |
2019-06-27 |
Alexion Pharmaceuticals Inc. |
Humanized anti-cd200 antibodies and uses thereof
|
WO2019126133A1
(en)
|
2017-12-20 |
2019-06-27 |
Alexion Pharmaceuticals, Inc. |
Liquid formulations of anti-cd200 antibodies
|
AU2019234213A1
(en)
|
2018-03-12 |
2020-09-03 |
Zoetis Services Llc |
Anti-NGF antibodies and methods thereof
|
EP3775900A1
(en)
|
2018-03-26 |
2021-02-17 |
Alexion Pharmaceuticals, Inc. |
High throughput method for measuring the protease activity of complement c3 convertase
|
US20210238289A1
(en)
|
2018-06-04 |
2021-08-05 |
Biogen Ma Inc. |
Anti-vla-4 antibodies having reduced effector function
|
EP3810095A1
(en)
|
2018-06-20 |
2021-04-28 |
Progenity, Inc. |
Treatment of a disease of the gastrointestinal tract with a tnf inhibitor
|
AU2019299444A1
(en)
|
2018-07-03 |
2021-01-14 |
Novartis Ag |
Methods of treating or selecting a treatment for a subject resistant to tnf inhibitor using a NLRP3 antagonist
|
EP3863672A4
(en)
|
2018-10-11 |
2022-06-29 |
The Scripps Research Institute |
Antibody compounds with reactive arginine and related antibody drug conjugates
|
EP3870168A1
(en)
|
2018-10-24 |
2021-09-01 |
Novartis AG |
Compounds and compositions for treating conditions associated with nlrp activity
|
AR117192A1
(es)
*
|
2018-11-05 |
2021-07-21 |
Beijing Hanmi Pharmaceutical Co Ltd |
ANTICUERPO BIESPECÍFICO HETERODIMÉRICO SIMILAR EN ESTRUCTURA AL ANTICUERPO NATURAL ANTI-TNFa / ANTI-IL-17A, Y MÉTODO PARA SU PREPARACIÓN
|
HUP1800376A2
(hu)
|
2018-11-07 |
2020-05-28 |
Richter Gedeon Nyrt |
Sejttenyészetben elõállított rekombináns glikoprotein glikozilációs-mintázatának megváltoztatására szolgáló módszer
|
CN113015730A
(zh)
|
2018-11-13 |
2021-06-22 |
诺华股份有限公司 |
用于治疗与nlrp活性相关的病症的化合物和组合物
|
CN113166081A
(zh)
|
2018-11-13 |
2021-07-23 |
诺华股份有限公司 |
用于治疗与nlrp活性相关的病症的化合物和组合物
|
WO2020106757A1
(en)
|
2018-11-19 |
2020-05-28 |
Progenity, Inc. |
Ingestible device for delivery of therapeutic agent to the gastrointestinal tract
|
WO2020118011A1
(en)
|
2018-12-06 |
2020-06-11 |
Alexion Pharmaceuticals, Inc. |
Anti-alk2 antibodies and uses thereof
|
CA3124730A1
(en)
|
2018-12-25 |
2020-07-02 |
Institute Of Basic Medical Sciences Chinese Academy Of Medical Sciences |
Small rna medicament for prevention and treatment of inflammation-related diseases and combinations thereof
|
EP3914583A1
(en)
|
2019-01-22 |
2021-12-01 |
Novartis AG |
Compounds and compositions for treating conditions associated with nlrp activity
|
HUP1900112A1
(hu)
|
2019-04-04 |
2020-10-28 |
Richter Gedeon Nyrt |
Immunglobulinok affinitás kromatográfiájának fejlesztése kötést megelõzõ flokkulálás alkalmazásával
|
KR102323342B1
(ko)
*
|
2019-04-26 |
2021-11-08 |
주식회사 와이바이오로직스 |
IL-17A 및 TNF-α에 특이적으로 결합하는 이중표적 항체
|
US11780911B2
(en)
|
2019-05-23 |
2023-10-10 |
Janssen Biotech, Inc. |
Method of treating inflammatory bowel disease with a combination therapy of antibodies to IL-23 and TNF alpha
|
WO2021002887A1
(en)
|
2019-07-02 |
2021-01-07 |
Novartis Inflammasome Research, Inc. |
Gut-targeted nlrp3 antagonists and their use in therapy
|
WO2021005607A1
(en)
*
|
2019-07-09 |
2021-01-14 |
National Institute For Biotechnology In The Negev Ltd. |
Antibodies with reduced immunogenicity
|
US11707610B2
(en)
|
2019-12-13 |
2023-07-25 |
Biora Therapeutics, Inc. |
Ingestible device for delivery of therapeutic agent to the gastrointestinal tract
|
FR3104582A1
(fr)
|
2019-12-17 |
2021-06-18 |
Commissariat A L'energie Atomique Et Aux Energies Alternatives |
Variants de l’adalimumab au potentiel immunogène réduit
|
CN115397848A
(zh)
|
2020-02-05 |
2022-11-25 |
拉利玛生物医药公司 |
Tat肽结合蛋白及其用途
|
US20230095053A1
(en)
|
2020-03-03 |
2023-03-30 |
Sutro Biopharma, Inc. |
Antibodies comprising site-specific glutamine tags, methods of their preparation and methods of their use
|
EP4136459A1
(en)
|
2020-04-13 |
2023-02-22 |
Abbott Laboratories |
Methods, complexes and kits for detecting or determining an amount of a ss-coronavirus antibody in a sample
|
KR20230042301A
(ko)
|
2020-08-04 |
2023-03-28 |
애벗트 라보라토리이즈 |
샘플에서 sars-cov-2 단백질을 검출하기 위한 개선된 방법 및 키트
|
CN111944052B
(zh)
*
|
2020-08-26 |
2022-02-11 |
中国药科大学 |
抗TNF-α/PD-1双特异性抗体及其应用
|
CN112010970B
(zh)
*
|
2020-10-30 |
2021-01-12 |
迈威(上海)生物科技股份有限公司 |
一种去除重组表达抗体聚体和降解产物的方法
|
WO2023102384A1
(en)
|
2021-11-30 |
2023-06-08 |
Abbott Laboratories |
Use of one or more biomarkers to determine traumatic brain injury (tbi) in a subject having received a head computerized tomography scan that is negative for a tbi
|
WO2022119841A1
(en)
|
2020-12-01 |
2022-06-09 |
Abbott Laboratories |
Use of one or more biomarkers to determine traumatic brain injury (tbi) in a subject having received a head computerized tomography scan that is negative for a tbi
|
US11672929B2
(en)
|
2020-12-02 |
2023-06-13 |
Breathe Restore, Inc. |
Product delivery devices and methods
|
EP4261222A1
(en)
|
2020-12-09 |
2023-10-18 |
HK inno.N Corporation |
ANTI-OX40L ANTIBODY, ANTI-OX40L/ANTI-TNFalpha BISPECIFIC ANTIBODY, AND USES THEREOF
|
US20240101715A1
(en)
*
|
2020-12-18 |
2024-03-28 |
Kindred Biosciences, Inc. |
Tnf alpha and ngf antibodies for veterinary use
|
EP4271998A1
(en)
|
2020-12-30 |
2023-11-08 |
Abbott Laboratories |
Methods for determining sars-cov-2 antigen and anti-sars-cov-2 antibody in a sample
|
AR124681A1
(es)
|
2021-01-20 |
2023-04-26 |
Abbvie Inc |
Conjugados anticuerpo-fármaco anti-egfr
|
CA3216585A1
(en)
|
2021-04-27 |
2022-11-03 |
Nathaniel SILVER |
Non-viral dna vectors expressing therapeutic antibodies and uses thereof
|
WO2022232286A1
(en)
|
2021-04-27 |
2022-11-03 |
Generation Bio Co. |
Non-viral dna vectors expressing anti-coronavirus antibodies and uses thereof
|
US20220381796A1
(en)
|
2021-05-18 |
2022-12-01 |
Abbott Laboratories |
Methods of evaluating brain injury in a pediatric subject
|
EP4356129A1
(en)
|
2021-06-14 |
2024-04-24 |
Abbott Laboratories |
Methods of diagnosing or aiding in diagnosis of brain injury caused by acoustic energy, electromagnetic energy, an over pressurization wave, and/or blast wind
|
WO2022271782A1
(en)
*
|
2021-06-22 |
2022-12-29 |
University Of Virginia Patent Foundation |
Compositions and methods for detecting and regulating fibronectin-integrin interactions and signaling
|
WO2023025248A1
(zh)
|
2021-08-26 |
2023-03-02 |
映恩生物制药(苏州)有限公司 |
一种甾体化合物及其缀合物
|
CA3230038A1
(en)
|
2021-08-31 |
2023-03-09 |
Hongwei Zhang |
Methods and systems of diagnosing brain injury
|
AU2022354059A1
(en)
|
2021-09-30 |
2024-03-28 |
Abbott Laboratories |
Methods and systems of diagnosing brain injury
|
WO2023114978A1
(en)
|
2021-12-17 |
2023-06-22 |
Abbott Laboratories |
Systems and methods for determining uch-l1, gfap, and other biomarkers in blood samples
|
US20230213536A1
(en)
|
2021-12-28 |
2023-07-06 |
Abbott Laboratories |
Use of biomarkers to determine sub-acute traumatic brain injury (tbi) in a subject having received a head computerized tomography (ct) scan that is negative for a tbi or no head ct scan
|
WO2023150652A1
(en)
|
2022-02-04 |
2023-08-10 |
Abbott Laboratories |
Lateral flow methods, assays, and devices for detecting the presence or measuring the amount of ubiquitin carboxy-terminal hydrolase l1 and/or glial fibrillary acidic protein in a sample
|
WO2023177655A1
(en)
|
2022-03-14 |
2023-09-21 |
Generation Bio Co. |
Heterologous prime boost vaccine compositions and methods of use
|
WO2024006681A1
(en)
*
|
2022-06-28 |
2024-01-04 |
Adafre Biosciences, Llc |
Anti-tnf-αlpha antibodies and compositions
|
WO2024006876A1
(en)
|
2022-06-29 |
2024-01-04 |
Abbott Laboratories |
Magnetic point-of-care systems and assays for determining gfap in biological samples
|
CN116903738A
(zh)
*
|
2022-08-02 |
2023-10-20 |
北京绿竹生物技术股份有限公司 |
一种低甘露糖型抗人肿瘤坏死因子-α单抗及其用途
|
WO2024054934A1
(en)
|
2022-09-07 |
2024-03-14 |
Mdx Management Llc |
Shp-1 inhibitors for treating cancer
|
WO2024059708A1
(en)
|
2022-09-15 |
2024-03-21 |
Abbott Laboratories |
Biomarkers and methods for differentiating between mild and supermild traumatic brain injury
|