HU188207B - New process for preparing phenyl-ethanol-amines - Google Patents

New process for preparing phenyl-ethanol-amines Download PDF

Info

Publication number
HU188207B
HU188207B HU8330A HU3080A HU188207B HU 188207 B HU188207 B HU 188207B HU 8330 A HU8330 A HU 8330A HU 3080 A HU3080 A HU 3080A HU 188207 B HU188207 B HU 188207B
Authority
HU
Hungary
Prior art keywords
formula
priority
amino
carboxylic acid
tert
Prior art date
Application number
HU8330A
Other languages
English (en)
Hungarian (hu)
Inventor
Jarkko Ruohonen
Kauko Nieminen
Johannes Keck
Gerd Krueger
Original Assignee
Dr Karl Thomae Gmbh,De
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FI790067A external-priority patent/FI59396C/fi
Priority claimed from DE19792942723 external-priority patent/DE2942723A1/de
Application filed by Dr Karl Thomae Gmbh,De filed Critical Dr Karl Thomae Gmbh,De
Publication of HU188207B publication Critical patent/HU188207B/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00Preparation of carboxylic acid amides
    • C07C231/06Preparation of carboxylic acid amides from nitriles by transformation of cyano groups into carboxamide groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/01Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/12Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pulmonology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

Neue alpha-Acyloxy-acetamide der allgemeinen Formel (I), in der R&ind1! ein Chlor- oder Bromatom; R&ind2! die Trifluormethylgruppe, ein Fluor- oder Chloratom; R&ind3! einen verzweigten Alkylrest oder eine Cycloalkylgruppe mit jeweils 3 bis 5 Kohlenstoffatomen u. R&ind4! einen Acylrest einer Carbonsaeure bedeuten. Diese neuen Zwischenprodukte lassen sich zu den entsprechenden Phenyl-aethanolaminen reduzieren, welche wertvolle pharmakologische Eigenschaften aufweisen, insbesondere broncholytische Wirkungen. Die neuen Zwischenprodukte erhaelt man durch Umsetzung eines entsprechenden Benzaldehyds mit einem entsprechenden Isonitril und einer entsprechenden Carbonsaeure.
HU8330A 1979-01-10 1980-01-09 New process for preparing phenyl-ethanol-amines HU188207B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI790067A FI59396C (fi) 1979-01-10 1979-01-10 Foerfarande foer framstaellning av 2-(4-amino-3,5-diklorfenyl)-2-karboxi-n-tert-butylacetamider
DE19792942723 DE2942723A1 (de) 1979-10-23 1979-10-23 Neue (alpha) -acyloxy-acetamide, deren herstellung und verwendung als zwischenprokukte

Publications (1)

Publication Number Publication Date
HU188207B true HU188207B (en) 1986-03-28

Family

ID=25781629

Family Applications (2)

Application Number Title Priority Date Filing Date
HU8330A HU188207B (en) 1979-01-10 1980-01-09 New process for preparing phenyl-ethanol-amines
HU8041A HU181681B (en) 1979-01-10 1980-01-09 Process for producing new l-acyloxy-l/p-amino-phenyl/-acetamino derivatives

Family Applications After (1)

Application Number Title Priority Date Filing Date
HU8041A HU181681B (en) 1979-01-10 1980-01-09 Process for producing new l-acyloxy-l/p-amino-phenyl/-acetamino derivatives

Country Status (18)

Country Link
AT (1) AT367398B (de)
BG (1) BG33584A3 (de)
CA (1) CA1146958A (de)
CH (1) CH645611A5 (de)
CS (1) CS214689B2 (de)
DD (2) DD150198A5 (de)
DK (2) DK159263C (de)
ES (1) ES487548A0 (de)
GR (1) GR74391B (de)
HU (2) HU188207B (de)
NL (1) NL8000126A (de)
NO (2) NO148522C (de)
PL (2) PL126876B1 (de)
PT (1) PT70661A (de)
RO (1) RO78779A (de)
SE (2) SE447102B (de)
SU (1) SU884563A3 (de)
YU (1) YU4880A (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR102020008433A2 (pt) 2020-04-28 2021-11-03 Universidade Federal Do Parana Repelentes de artrópodes obtidos a partir da transformação química de ácido lático, lactatos ou outros derivados do ácido lático

Also Published As

Publication number Publication date
BG33584A3 (en) 1983-03-15
DD156179A5 (de) 1982-08-04
SE452979B (sv) 1988-01-04
DK159263C (da) 1991-02-18
DK159262B (da) 1990-09-24
ES8102547A1 (es) 1981-01-16
GR74391B (de) 1984-06-28
NO148997B (no) 1983-10-17
DD150198A5 (de) 1981-08-19
AT367398B (de) 1982-06-25
NO823159L (no) 1980-07-11
NO148522C (no) 1983-10-26
DK517289A (da) 1989-10-18
CS214689B2 (en) 1982-05-28
NO148522B (no) 1983-07-18
SE8405631L (sv) 1984-11-09
YU4880A (en) 1983-06-30
DK8480A (da) 1980-07-11
ATA3380A (de) 1981-11-15
PL126876B1 (en) 1983-09-30
RO78779A (ro) 1982-04-12
SE447102B (sv) 1986-10-27
SE8000175L (sv) 1980-07-11
CH645611A5 (en) 1984-10-15
DK517289D0 (da) 1989-10-18
SU884563A3 (ru) 1981-11-23
NL8000126A (nl) 1980-07-14
DK159263B (da) 1990-09-24
PT70661A (de) 1980-02-01
CA1146958A (en) 1983-05-24
DK159262C (da) 1991-02-18
ES487548A0 (es) 1981-01-16
NO794314L (no) 1980-07-11
PL126046B1 (en) 1983-07-30
PL221288A1 (de) 1980-12-15
NO148997C (no) 1984-01-25
HU181681B (en) 1983-11-28
SE8405631D0 (sv) 1984-11-09

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