HU181681B - Process for producing new l-acyloxy-l/p-amino-phenyl/-acetamino derivatives - Google Patents
Process for producing new l-acyloxy-l/p-amino-phenyl/-acetamino derivatives Download PDFInfo
- Publication number
- HU181681B HU181681B HU8041A HU4180A HU181681B HU 181681 B HU181681 B HU 181681B HU 8041 A HU8041 A HU 8041A HU 4180 A HU4180 A HU 4180A HU 181681 B HU181681 B HU 181681B
- Authority
- HU
- Hungary
- Prior art keywords
- formula
- carboxylic acid
- defined above
- acyloxy
- amino
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/06—Preparation of carboxylic acid amides from nitriles by transformation of cyano groups into carboxamide groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pulmonology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Neue alpha-Acyloxy-acetamide der allgemeinen Formel (I), in der R&ind1! ein Chlor- oder Bromatom; R&ind2! die Trifluormethylgruppe, ein Fluor- oder Chloratom; R&ind3! einen verzweigten Alkylrest oder eine Cycloalkylgruppe mit jeweils 3 bis 5 Kohlenstoffatomen u. R&ind4! einen Acylrest einer Carbonsaeure bedeuten. Diese neuen Zwischenprodukte lassen sich zu den entsprechenden Phenyl-aethanolaminen reduzieren, welche wertvolle pharmakologische Eigenschaften aufweisen, insbesondere broncholytische Wirkungen. Die neuen Zwischenprodukte erhaelt man durch Umsetzung eines entsprechenden Benzaldehyds mit einem entsprechenden Isonitril und einer entsprechenden Carbonsaeure.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FI790067A FI59396C (fi) | 1979-01-10 | 1979-01-10 | Foerfarande foer framstaellning av 2-(4-amino-3,5-diklorfenyl)-2-karboxi-n-tert-butylacetamider |
| DE19792942723 DE2942723A1 (de) | 1979-10-23 | 1979-10-23 | Neue (alpha) -acyloxy-acetamide, deren herstellung und verwendung als zwischenprokukte |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HU181681B true HU181681B (en) | 1983-11-28 |
Family
ID=25781629
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU8041A HU181681B (en) | 1979-01-10 | 1980-01-09 | Process for producing new l-acyloxy-l/p-amino-phenyl/-acetamino derivatives |
| HU8330A HU188207B (en) | 1979-01-10 | 1980-01-09 | New process for preparing phenyl-ethanol-amines |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU8330A HU188207B (en) | 1979-01-10 | 1980-01-09 | New process for preparing phenyl-ethanol-amines |
Country Status (18)
| Country | Link |
|---|---|
| AT (1) | AT367398B (de) |
| BG (1) | BG33584A3 (de) |
| CA (1) | CA1146958A (de) |
| CH (1) | CH645611A5 (de) |
| CS (1) | CS214689B2 (de) |
| DD (2) | DD150198A5 (de) |
| DK (2) | DK159263C (de) |
| ES (1) | ES8102547A1 (de) |
| GR (1) | GR74391B (de) |
| HU (2) | HU181681B (de) |
| NL (1) | NL8000126A (de) |
| NO (2) | NO148522C (de) |
| PL (2) | PL126876B1 (de) |
| PT (1) | PT70661A (de) |
| RO (1) | RO78779A (de) |
| SE (2) | SE447102B (de) |
| SU (1) | SU884563A3 (de) |
| YU (1) | YU4880A (de) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR102020008433A2 (pt) | 2020-04-28 | 2021-11-03 | Universidade Federal Do Parana | Repelentes de artrópodes obtidos a partir da transformação química de ácido lático, lactatos ou outros derivados do ácido lático |
-
1979
- 1979-12-24 BG BG7946027A patent/BG33584A3/xx unknown
- 1979-12-28 NO NO794314A patent/NO148522C/no unknown
-
1980
- 1980-01-04 GR GR60893A patent/GR74391B/el unknown
- 1980-01-04 SU SU802863255A patent/SU884563A3/ru active
- 1980-01-04 AT AT0003380A patent/AT367398B/de not_active IP Right Cessation
- 1980-01-07 CH CH6680A patent/CH645611A5/de not_active IP Right Cessation
- 1980-01-07 PT PT70661A patent/PT70661A/de not_active IP Right Cessation
- 1980-01-07 CS CS80164A patent/CS214689B2/cs unknown
- 1980-01-08 CA CA000343261A patent/CA1146958A/en not_active Expired
- 1980-01-08 YU YU00048/80A patent/YU4880A/xx unknown
- 1980-01-08 DD DD80218350A patent/DD150198A5/de unknown
- 1980-01-08 DD DD80227454A patent/DD156179A5/de unknown
- 1980-01-08 DK DK008480A patent/DK159263C/da not_active IP Right Cessation
- 1980-01-09 HU HU8041A patent/HU181681B/hu unknown
- 1980-01-09 PL PL1980221288A patent/PL126876B1/pl unknown
- 1980-01-09 NL NL8000126A patent/NL8000126A/nl not_active Application Discontinuation
- 1980-01-09 SE SE8000175A patent/SE447102B/sv not_active IP Right Cessation
- 1980-01-09 ES ES487548A patent/ES8102547A1/es not_active Expired
- 1980-01-09 HU HU8330A patent/HU188207B/hu unknown
- 1980-01-09 RO RO8099824A patent/RO78779A/ro unknown
- 1980-01-09 PL PL1980234384A patent/PL126046B1/pl unknown
-
1982
- 1982-09-17 NO NO823159A patent/NO148997C/no unknown
-
1984
- 1984-11-09 SE SE8405631A patent/SE452979B/sv not_active IP Right Cessation
-
1989
- 1989-10-18 DK DK517289A patent/DK159262C/da not_active IP Right Cessation
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JPS6193172A (ja) | イソオキサゾールカルボン酸誘導体 | |
| HU215843B (hu) | Eljárás 2-ciano-3-hidroxi-enamidok és e vegyületeket hatóanyagként tartalmazó gyógyszerkészítmények előállítására | |
| FR2689508A1 (fr) | Dérivés de l'imidazole, leur procédé de préparation et leur application en thérapeutique. | |
| HU181681B (en) | Process for producing new l-acyloxy-l/p-amino-phenyl/-acetamino derivatives | |
| HU191824B (en) | Process for producing new pyridine and pyrimidine derivatives utilizable as intermediares producing antiflogistic and immunkregulating compounds | |
| JPS5826342B2 (ja) | シンキピラゾリルオキシサクサンユウドウタイ ノ セイホウ | |
| HU216444B (hu) | Eljárás fenil-ecetsav-származékok előállítására | |
| CH634826A5 (de) | N-substituierte alpha-ketocarbonsaeureamide. | |
| JP2006513242A (ja) | インデノンカルボン酸誘導体ならびに糖尿病および脂質代謝異常を治療および予防するためのそれらの使用 | |
| JP2595605B2 (ja) | ２−置換オキシイミノ−３−オキソ酪酸の製造法 | |
| KATO et al. | Reaction of Ethyl 4-Halo-3-oxobutanoate with Diethyl Malonate, Methyl Cyanoacetate, and Malononitrile | |
| Ramirez et al. | New syntheses of 5-acylhydantoins and of 5-acyl-4-hydroxyoxazoles: Precursors of β-keto-β-amino acids and of β-keto-α-hydroxy acid amides | |
| JPH04270248A (ja) | ベンジルフェニルケトン誘導体 | |
| US4866197A (en) | Production of N-((2-alkoxy-6-methoxy-5-(trifluoromethyl)-1-naphthalenyl)carbonyl)-N-methylglycine esters | |
| JP3420321B2 (ja) | ２，４，５−トリハロゲノ−３−メチル安息香酸の製造方法 | |
| US2971021A (en) | 1-amino-1-carboalkoxycyclohexanes | |
| KR100467552B1 (ko) | 약제의 제조에 중간체로서 유용한 4-(4-옥소사이클로헥실)벤즈아미드 | |
| JP3710506B2 (ja) | 新規なベンゼン誘導体 | |
| DE3914227A1 (de) | Verfahren zur herstellung von 2,7-difluor-9-fluorenon und neue zwischenprodukte | |
| KR840000945B1 (ko) | 페닐 에탄올 아민의 제조방법 | |
| JP2671401B2 (ja) | α‐アミノチオアセトアミド誘導体およびその製造法 | |
| Jonczyk et al. | Generation and Reactions of Carbanions from Dialkylamino (Methylthio) Acetonitriles | |
| JP2717997B2 (ja) | 新規ヒドラゾン化合物、及びトリアゾールの製法 | |
| JPS606938B2 (ja) | ３−アシルアゾプロピオン酸エステルの製法 | |
| WO2001029003A1 (en) | Process for the preparation of 1-(6-methylpyridin-3-yl)-2-(4-methylthiophenyl)-ethanone and its use in the synthesis of diarylpyridines |