JP4169478B2
(ja)
*
|
1998-04-21 |
2008-10-22 |
マイクロメット アーゲー |
Cd19×cd3特異的ポリペプチドおよびその使用
|
PL200134B1
(pl)
|
1999-05-07 |
2008-12-31 |
Genentech Inc |
Zastosowanie przeciwciała anty-CD20
|
US8383081B2
(en)
|
1999-05-10 |
2013-02-26 |
Immunomedics, Inc. |
Anti-CD74 immunoconjugates and methods of use
|
US8119101B2
(en)
|
1999-05-10 |
2012-02-21 |
The Ohio State University |
Anti-CD74 immunoconjugates and methods of use
|
US7829064B2
(en)
|
1999-05-10 |
2010-11-09 |
Immunomedics, Inc. |
Anti-CD74 immunoconjugates and methods
|
ES2331644T3
(es)
|
1999-06-09 |
2010-01-12 |
Immunomedics, Inc. |
Inmunoterapia de trastornos autoinmunes usando anticuerpos cuya diana son celulas b.
|
EP1543839B1
(en)
*
|
1999-06-09 |
2017-09-20 |
Immunomedics, Inc. |
Immunotherapy of autoimmune disorders using antibodies which target B-cells
|
DE19962583A1
(de)
*
|
1999-12-23 |
2001-06-28 |
Mueller Hermelink Hans Konrad |
Antikörper gegen Plasmazellen
|
WO2002077029A2
(en)
*
|
2000-11-07 |
2002-10-03 |
City Of Hope |
Cd19-specific redirected immune cells
|
US20080260731A1
(en)
*
|
2002-03-01 |
2008-10-23 |
Bernett Matthew J |
Optimized antibodies that target cd19
|
US20160279239A1
(en)
|
2011-05-02 |
2016-09-29 |
Immunomedics, Inc. |
Subcutaneous administration of anti-cd74 antibody for systemic lupus erythematosus and autoimmune disease
|
US9770517B2
(en)
|
2002-03-01 |
2017-09-26 |
Immunomedics, Inc. |
Anti-Trop-2 antibody-drug conjugates and uses thereof
|
US7425618B2
(en)
|
2002-06-14 |
2008-09-16 |
Medimmune, Inc. |
Stabilized anti-respiratory syncytial virus (RSV) antibody formulations
|
US9453251B2
(en)
|
2002-10-08 |
2016-09-27 |
Pfenex Inc. |
Expression of mammalian proteins in Pseudomonas fluorescens
|
US7820166B2
(en)
|
2002-10-11 |
2010-10-26 |
Micromet Ag |
Potent T cell modulating molecules
|
DE602004025101D1
(de)
|
2003-05-31 |
2010-03-04 |
Micromet Ag |
Humane anti-humane cd3-bindungsmoleküle
|
JP2008501621A
(ja)
*
|
2003-05-31 |
2008-01-24 |
マイクロメット アクツィエン ゲゼルシャフト |
B細胞関連疾患を処置するための二重特異性抗cd3、抗cd19抗体構築物を含む薬学的組成物
|
CA2528549A1
(en)
|
2003-06-06 |
2005-06-02 |
Medimmune, Inc. |
Use of epha4 and modulator of epha4 for diagnosis, treatment and prevention of cancer
|
US7902338B2
(en)
|
2003-07-31 |
2011-03-08 |
Immunomedics, Inc. |
Anti-CD19 antibodies
|
EP1648512A4
(en)
*
|
2003-07-31 |
2009-01-21 |
Immunomedics Inc |
ANTI-CD19 ANTIBODIES
|
DK1673398T3
(da)
|
2003-10-16 |
2011-04-18 |
Micromet Ag |
Multispecifikke, deimmuniserede CD3-bindere
|
DK1691833T3
(da)
|
2003-11-28 |
2010-05-03 |
Micromet Ag |
Præparater der omfatter polypeptider
|
US7235641B2
(en)
|
2003-12-22 |
2007-06-26 |
Micromet Ag |
Bispecific antibodies
|
US8883160B2
(en)
|
2004-02-13 |
2014-11-11 |
Ibc Pharmaceuticals, Inc. |
Dock-and-lock (DNL) complexes for therapeutic and diagnostic use
|
US9550838B2
(en)
|
2004-02-13 |
2017-01-24 |
Ibc Pharmaceuticals, Inc. |
Dock-and-lock (DNL) complexes for therapeutic and diagnostic use
|
MXPA06009253A
(es)
|
2004-02-16 |
2007-04-18 |
Micromet Ag |
Moleculas de enlace menos inmunogenicas.
|
CA2574953A1
(en)
|
2004-07-26 |
2006-02-09 |
Dow Global Technolgies Inc. |
Process for improved protein expression by strain engineering
|
AU2005299355A1
(en)
|
2004-10-27 |
2006-05-04 |
Medimmune, Llc |
Modulation of antibody specificity by tailoring the affinity to cognate antigens
|
US9707302B2
(en)
|
2013-07-23 |
2017-07-18 |
Immunomedics, Inc. |
Combining anti-HLA-DR or anti-Trop-2 antibodies with microtubule inhibitors, PARP inhibitors, bruton kinase inhibitors or phosphoinositide 3-kinase inhibitors significantly improves therapeutic outcome in cancer
|
US20160355591A1
(en)
|
2011-05-02 |
2016-12-08 |
Immunomedics, Inc. |
Subcutaneous anti-hla-dr monoclonal antibody for treatment of hematologic malignancies
|
US10058621B2
(en)
|
2015-06-25 |
2018-08-28 |
Immunomedics, Inc. |
Combination therapy with anti-HLA-DR antibodies and kinase inhibitors in hematopoietic cancers
|
US8349332B2
(en)
|
2005-04-06 |
2013-01-08 |
Ibc Pharmaceuticals, Inc. |
Multiple signaling pathways induced by hexavalent, monospecific and bispecific antibodies for enhanced toxicity to B-cell lymphomas and other diseases
|
US8475794B2
(en)
|
2005-04-06 |
2013-07-02 |
Ibc Pharmaceuticals, Inc. |
Combination therapy with anti-CD74 antibodies provides enhanced toxicity to malignancies, Autoimmune disease and other diseases
|
PL1874819T3
(pl)
|
2005-04-18 |
2015-10-30 |
Amgen Res Munich Gmbh |
Przeciwciała neutralizujące ludzki czynnik stymulujący wzrost kolonii granulocytów i makrofagów
|
ES2417065T3
(es)
|
2005-04-26 |
2013-08-05 |
Trion Pharma Gmbh |
Combinación de anticuerpos con glucocorticoides para el tratamiento del cáncer
|
AU2006262232A1
(en)
|
2005-06-20 |
2007-01-04 |
Medarex, Inc. |
CD19 antibodies and their uses
|
AU2006283532B2
(en)
*
|
2005-08-19 |
2012-04-26 |
Abbvie Inc. |
Dual variable domain immunoglobin and uses thereof
|
CA2625440C
(en)
|
2005-10-11 |
2023-06-13 |
Micromet Ag |
Compositions comprising cross-species-specific antibodies and uses thereof
|
DK1976886T3
(en)
*
|
2005-12-16 |
2015-03-02 |
Amgen Res Munich Gmbh |
Means and methods for the treatment of tumor diseases
|
DK1976880T3
(en)
|
2005-12-21 |
2016-09-26 |
Amgen Res (Munich) Gmbh |
Pharmaceutical compositions with resistance to soluble cea
|
PT1989544E
(pt)
*
|
2006-03-02 |
2011-09-26 |
Antitope Ltd |
Ensaios com células t
|
SI2059536T1
(sl)
|
2006-08-14 |
2014-06-30 |
Xencor, Inc. |
Optimirana protitelesa, ki ciljajo CD19
|
KR101456728B1
(ko)
*
|
2006-09-08 |
2014-10-31 |
메디뮨 엘엘씨 |
인간화 항-cd19 항체, 및 이것의 종양학, 이식 및 자가면역 질환의 치료에서의 용도
|
CA2682626A1
(en)
*
|
2007-04-03 |
2008-10-09 |
Micromet Ag |
Cross-species-specific bispecific binders
|
KR101589759B1
(ko)
|
2007-04-03 |
2016-01-29 |
암젠 리서치 (뮌헨) 게엠베하 |
종간 특이적 cd3―입실론 결합 도메인
|
JP2010524851A
(ja)
†
|
2007-04-03 |
2010-07-22 |
マイクロメット アーゲー |
種間特異的結合ドメイン
|
CN101688213A
(zh)
|
2007-04-27 |
2010-03-31 |
陶氏环球技术公司 |
用于快速筛选微生物宿主以鉴定某些在表达异源蛋白质方面具有改善的产量和/或质量的菌株的方法
|
US9580719B2
(en)
|
2007-04-27 |
2017-02-28 |
Pfenex, Inc. |
Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins
|
US20090053786A1
(en)
*
|
2007-07-09 |
2009-02-26 |
Yung-Hsiang Kao |
Prevention of disulfide bond reduction during recombinant production of polypeptides
|
CN101952415B
(zh)
*
|
2007-07-31 |
2017-06-27 |
生命扫描有限公司 |
人胚胎干细胞的分化
|
US20090155275A1
(en)
|
2007-07-31 |
2009-06-18 |
Medimmune, Llc |
Multispecific epitope binding proteins and uses thereof
|
EP2211904B1
(en)
*
|
2007-10-19 |
2016-08-17 |
Seattle Genetics, Inc. |
Cd19 binding agents and uses thereof
|
EP2225275A4
(en)
*
|
2007-11-28 |
2013-04-03 |
Medimmune Llc |
PROTEIN FORMULATION
|
NZ591134A
(en)
|
2008-10-01 |
2012-08-31 |
Micromet Ag |
Cross-species-specific (human and primate) bispecific single chain antibody that binds both cd3 (epsilon) epitope and prostate specific membrane antigen (pmsa)
|
US10981998B2
(en)
|
2008-10-01 |
2021-04-20 |
Amgen Research (Munich) Gmbh |
Cross-species-specific single domain bispecific single chain antibody
|
US9260522B2
(en)
|
2008-10-01 |
2016-02-16 |
Amgen Research (Munich) Gmbh |
Bispecific single chain antibodies with specificity for high molecular weight target antigens
|
RU2547600C2
(ru)
*
|
2008-10-01 |
2015-04-10 |
Эмджен Рисерч (Мьюник) Гмбх |
Pscaxcd3, cd19xcd3, c-metxcd3, эндосиалинxcd3, epcamxcd3, igf-1rxcd3 или fap-альфаxcd3 биспецифическое одноцепочечное антитело с межвидовой специфичностью
|
NO2918604T3
(ru)
*
|
2008-11-07 |
2018-05-19 |
|
|
EP2982696B1
(en)
*
|
2008-11-07 |
2019-03-27 |
Amgen Research (Munich) GmbH |
Treatment of acute lymphoblastic leukemia
|
WO2010084160A1
(en)
|
2009-01-21 |
2010-07-29 |
Oryzon Genomics S.A. |
Phenylcyclopropylamine derivatives and their medical use
|
US9676845B2
(en)
*
|
2009-06-16 |
2017-06-13 |
Hoffmann-La Roche, Inc. |
Bispecific antigen binding proteins
|
US20110002931A1
(en)
|
2009-06-23 |
2011-01-06 |
Alexion Pharmaceuticals, Inc. |
Bispecific antibodies that bind to complement proteins
|
US9493578B2
(en)
|
2009-09-02 |
2016-11-15 |
Xencor, Inc. |
Compositions and methods for simultaneous bivalent and monovalent co-engagement of antigens
|
MX338041B
(es)
|
2009-09-25 |
2016-03-30 |
Oryzon Genomics Sa |
Inhibidores de demetilasa-1 especificos de lisina y su uso.
|
EP2486002B1
(en)
|
2009-10-09 |
2019-03-27 |
Oryzon Genomics, S.A. |
Substituted heteroaryl- and aryl- cyclopropylamine acetamides and their use
|
CN107227335A
(zh)
|
2009-10-27 |
2017-10-03 |
安进研发(慕尼黑)股份有限公司 |
用于施用CD19xCD3双特异性抗体的给药方案
|
CA2781682A1
(en)
|
2009-12-04 |
2011-06-09 |
Genentech, Inc. |
Multispecific antibodies, antibody analogs, compositions, and methods
|
WO2011079283A1
(en)
*
|
2009-12-23 |
2011-06-30 |
Bioalliance C.V. |
Anti-epcam antibodies that induce apoptosis of cancer cells and methods using same
|
US9186337B2
(en)
|
2010-02-24 |
2015-11-17 |
Oryzon Genomics S.A. |
Lysine demethylase inhibitors for diseases and disorders associated with Hepadnaviridae
|
US9616058B2
(en)
|
2010-02-24 |
2017-04-11 |
Oryzon Genomics, S.A. |
Potent selective LSD1 inhibitors and dual LSD1/MAO-B inhibitors for antiviral use
|
TWI653333B
(zh)
|
2010-04-01 |
2019-03-11 |
安進研究(慕尼黑)有限責任公司 |
跨物種專一性之PSMAxCD3雙專一性單鏈抗體
|
KR101794020B1
(ko)
|
2010-04-19 |
2017-11-06 |
오리존 지노믹스 에스.에이. |
라이신 특이적 디메틸라아제-1 억제제 및 이의 용도
|
WO2011139985A1
(en)
|
2010-05-03 |
2011-11-10 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of tumor
|
US8980933B2
(en)
|
2010-05-05 |
2015-03-17 |
Universitat Bayreuth |
Combretastatin analogs for use in the treatment of cancer
|
CN102250245B
(zh)
*
|
2010-05-27 |
2014-05-14 |
四川大学 |
抗b细胞淋巴瘤的双特异性抗体及其用途
|
WO2012013725A1
(en)
|
2010-07-28 |
2012-02-02 |
Medizinische Universität Wien |
Vinylogous chalcone derivatives and their medical use
|
CA2806252C
(en)
|
2010-07-29 |
2019-05-14 |
Xencor, Inc. |
Antibodies with modified isoelectric points
|
US9181198B2
(en)
|
2010-07-29 |
2015-11-10 |
Oryzon Genomics S.A. |
Arylcyclopropylamine based demethylase inhibitors of LSD1 and their medical use
|
WO2012013727A1
(en)
|
2010-07-29 |
2012-02-02 |
Oryzon Genomics S.A. |
Cyclopropylamine derivatives useful as lsd1 inhibitors
|
WO2012045883A1
(en)
|
2010-10-08 |
2012-04-12 |
Oryzon Genomics S.A. |
Cyclopropylamine inhibitors of oxidases
|
ES2563439T5
(es)
|
2010-10-27 |
2022-02-04 |
Amgen Res Munich Gmbh |
Medios y métodos para tratar LDCBG
|
EP2637670B2
(en)
|
2010-11-10 |
2024-03-13 |
Amgen Research (Munich) GmbH |
Prevention of adverse effects caused by cd3 specific binding domains
|
EP3974453A3
(en)
*
|
2010-11-16 |
2022-08-03 |
Amgen Inc. |
Agents and methods for treating diseases that correlate with bcma expression
|
WO2012072713A2
(en)
|
2010-11-30 |
2012-06-07 |
Oryzon Genomics, S.A. |
Lysine demethylase inhibitors for diseases and disorders associated with flaviviridae
|
EP2712315B1
(en)
|
2011-02-08 |
2021-11-24 |
Oryzon Genomics, S.A. |
Lysine demethylase inhibitors for myeloproliferative disorders
|
CA2827170A1
(en)
|
2011-02-11 |
2012-08-16 |
David M. Hilbert |
Monovalent and multivalent multispecific complexes and uses thereof
|
CA2832360C
(en)
|
2011-04-28 |
2022-05-03 |
Amgen Research (Munich) Gmbh |
Dosage regimen for administering a cd19xcd3 bispecific antibody to patients at risk for potential adverse effects
|
UA117072C2
(uk)
|
2011-05-21 |
2018-06-11 |
Макродженікс, Інк. |
Cd3-зв'язувальна молекула, здатна до зв'язування з cd3 людини, і cd3, що не є людським
|
CN103857699B
(zh)
|
2011-05-24 |
2016-08-31 |
泽恩格尼亚股份有限公司 |
多价和单价多特异性复合物及其用途
|
DK2718320T3
(en)
|
2011-06-10 |
2018-03-26 |
Medimmune Ltd |
ANTI-PSEUDOMONAS-PSL BINDING MOLECULES AND APPLICATIONS THEREOF
|
KR20200058583A
(ko)
*
|
2011-08-16 |
2020-05-27 |
모르포시스 아게 |
항-cd19 항체 및 질소 머스타드를 사용한 조합 요법
|
DE202012012998U1
(de)
|
2011-08-31 |
2014-06-13 |
Daniel Elias |
Bioaktive, regenerative Mischung zur Herstellung eines Ergänzungsnahrungsmittels
|
JP2014533929A
(ja)
|
2011-09-23 |
2014-12-18 |
アムゲン リサーチ (ミュンヘン) ゲーエムベーハー |
5t4およびcd3に対する二重特異的結合性分子
|
US10851178B2
(en)
|
2011-10-10 |
2020-12-01 |
Xencor, Inc. |
Heterodimeric human IgG1 polypeptides with isoelectric point modifications
|
CN107266345B
(zh)
|
2011-10-20 |
2021-08-17 |
奥瑞泽恩基因组学股份有限公司 |
作为lsd1抑制剂的(杂)芳基环丙胺化合物
|
RS58475B1
(sr)
|
2011-10-20 |
2019-04-30 |
Oryzon Genomics Sa |
Jedinjenja (hetero)aril ciklopropilamina kao lsd1 inhibitori
|
ES2859323T3
(es)
|
2011-11-07 |
2021-10-01 |
Medimmune Ltd |
Terapias de combinación que usan moléculas de unión anti-Psl y PcrV de Pseudomonas
|
TWI679212B
(zh)
|
2011-11-15 |
2019-12-11 |
美商安進股份有限公司 |
針對bcma之e3以及cd3的結合分子
|
US9757458B2
(en)
|
2011-12-05 |
2017-09-12 |
Immunomedics, Inc. |
Crosslinking of CD22 by epratuzumab triggers BCR signaling and caspase-dependent apoptosis in hematopoietic cancer cells
|
CA2853138A1
(en)
|
2011-12-05 |
2013-06-13 |
Immunomedics, Inc. |
Therapeutic use of anti-cd22 antibodies for inducing trogocytosis
|
US10633451B2
(en)
*
|
2012-02-03 |
2020-04-28 |
Hoffmann-La Roche Inc. |
Bispecific antibody molecules with antigen-transfected T-cells and their use in medicine
|
JP2015513399A
(ja)
|
2012-02-22 |
2015-05-14 |
ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア |
癌の治療のために有用なt細胞の存続的集団を作製するための組成物および方法
|
GB201203442D0
(en)
|
2012-02-28 |
2012-04-11 |
Univ Birmingham |
Immunotherapeutic molecules and uses
|
CA2864177C
(en)
|
2012-03-01 |
2019-11-26 |
Amgen Research (Munich) Gmbh |
Prolonged half-life albumin-binding protein fused bispecific antibodies
|
CN103382223B
(zh)
|
2012-04-01 |
2015-06-10 |
上海益杰生物技术有限公司 |
针对表皮生长因子受体隐蔽表位和t细胞抗原的多功能抗体多肽
|
WO2014004549A2
(en)
|
2012-06-27 |
2014-01-03 |
Amgen Inc. |
Anti-mesothelin binding proteins
|
US9765156B2
(en)
|
2012-07-13 |
2017-09-19 |
The Trustees Of The University Of Pennsylvania |
Enhancing activity of CAR T cells by co-introducing a bispecific antibody
|
US10131712B2
(en)
|
2012-08-14 |
2018-11-20 |
Ibc Pharmaceuticals, Inc. |
Combination therapy with T-cell redirecting bispecific antibodies and checkpoint inhibitors
|
US9382329B2
(en)
|
2012-08-14 |
2016-07-05 |
Ibc Pharmaceuticals, Inc. |
Disease therapy by inducing immune response to Trop-2 expressing cells
|
US20150231241A1
(en)
|
2012-08-14 |
2015-08-20 |
Ibc Pharmaceuticals, Inc. |
Combination therapy for inducing immune response to disease
|
US9682143B2
(en)
|
2012-08-14 |
2017-06-20 |
Ibc Pharmaceuticals, Inc. |
Combination therapy for inducing immune response to disease
|
EP3586874A1
(en)
|
2012-08-14 |
2020-01-01 |
IBC Pharmaceuticals, Inc. |
T-cell redirecting bispecific antibodies for treatment of disease
|
JOP20200236A1
(ar)
|
2012-09-21 |
2017-06-16 |
Regeneron Pharma |
الأجسام المضادة لمضاد cd3 وجزيئات ربط الأنتيجين ثنائية التحديد التي تربط cd3 وcd20 واستخداماتها
|
AR093297A1
(es)
|
2012-10-31 |
2015-05-27 |
Amgen Res (Munich) Gmbh |
Formulacion liquida que comprende un compuesto neutralizante de gm-csf
|
US9833410B2
(en)
|
2012-10-31 |
2017-12-05 |
Takeda Gmbh |
Lyophilized formulation comprising GM-CSF neutralizing compound
|
CN103833852A
(zh)
*
|
2012-11-23 |
2014-06-04 |
上海市肿瘤研究所 |
针对磷脂酰肌醇蛋白多糖-3和t细胞抗原的双特异性抗体
|
US10206918B2
(en)
|
2012-12-13 |
2019-02-19 |
Immunomedics, Inc. |
Efficacy of anti-HLA-DR antiboddy drug conjugate IMMU-140 (hL243-CL2A-SN-38) in HLA-DR positive cancers
|
US10744129B2
(en)
|
2012-12-13 |
2020-08-18 |
Immunomedics, Inc. |
Therapy of small-cell lung cancer (SCLC) with a topoisomerase-I inhibiting antibody-drug conjugate (ADC) targeting Trop-2
|
EP4035689A1
(en)
|
2012-12-13 |
2022-08-03 |
Immunomedics Inc. |
Dosages of immunoconjugates of antibodies and sn-38 for improved efficacy and decreased toxicity
|
US9492566B2
(en)
|
2012-12-13 |
2016-11-15 |
Immunomedics, Inc. |
Antibody-drug conjugates and uses thereof
|
US9107960B2
(en)
|
2012-12-13 |
2015-08-18 |
Immunimedics, Inc. |
Antibody-SN-38 immunoconjugates with a CL2A linker
|
US9931417B2
(en)
|
2012-12-13 |
2018-04-03 |
Immunomedics, Inc. |
Antibody-SN-38 immunoconjugates with a CL2A linker
|
US10413539B2
(en)
|
2012-12-13 |
2019-09-17 |
Immunomedics, Inc. |
Therapy for metastatic urothelial cancer with the antibody-drug conjugate, sacituzumab govitecan (IMMU-132)
|
US10137196B2
(en)
|
2012-12-13 |
2018-11-27 |
Immunomedics, Inc. |
Dosages of immunoconjugates of antibodies and SN-38 for improved efficacy and decreased toxicity
|
US9701759B2
(en)
|
2013-01-14 |
2017-07-11 |
Xencor, Inc. |
Heterodimeric proteins
|
CN110981964B
(zh)
|
2013-01-14 |
2023-09-15 |
Xencor股份有限公司 |
新型异二聚体蛋白
|
US10968276B2
(en)
|
2013-03-12 |
2021-04-06 |
Xencor, Inc. |
Optimized anti-CD3 variable regions
|
US10487155B2
(en)
|
2013-01-14 |
2019-11-26 |
Xencor, Inc. |
Heterodimeric proteins
|
US9605084B2
(en)
|
2013-03-15 |
2017-03-28 |
Xencor, Inc. |
Heterodimeric proteins
|
US10131710B2
(en)
|
2013-01-14 |
2018-11-20 |
Xencor, Inc. |
Optimized antibody variable regions
|
US11053316B2
(en)
|
2013-01-14 |
2021-07-06 |
Xencor, Inc. |
Optimized antibody variable regions
|
AU2014207549B2
(en)
|
2013-01-15 |
2018-12-06 |
Xencor, Inc. |
Rapid clearance of antigen complexes using novel antibodies
|
CN103965359B
(zh)
*
|
2013-01-24 |
2016-08-03 |
上海市肿瘤研究所 |
抗上皮细胞粘附分子和t细胞抗原的双特异性抗体
|
JO3519B1
(ar)
|
2013-01-25 |
2020-07-05 |
Amgen Inc |
تركيبات أجسام مضادة لأجل cdh19 و cd3
|
WO2014114801A1
(en)
|
2013-01-25 |
2014-07-31 |
Amgen Inc. |
Antibodies targeting cdh19 for melanoma
|
US9486475B2
(en)
|
2013-02-08 |
2016-11-08 |
Amgen Research (Munich) Gmbh |
PPS for the prevention of potential adverse effects caused by CD3 specific binding domains
|
JO3529B1
(ar)
|
2013-02-08 |
2020-07-05 |
Amgen Res Munich Gmbh |
مضاد التصاق خلايا الدم البيض من أجل التخفيف من الاثار السلبية الممكنة الناتجة عن مجالات ارتباط cd3- المحدد
|
WO2014138306A1
(en)
|
2013-03-05 |
2014-09-12 |
Baylor College Of Medicine |
Engager cells for immunotherapy
|
JP2016512199A
(ja)
|
2013-03-05 |
2016-04-25 |
ベイラー カレッジ オブ メディスンBaylor College Of Medicine |
腫瘍溶解性ウイルス
|
US10858417B2
(en)
|
2013-03-15 |
2020-12-08 |
Xencor, Inc. |
Heterodimeric proteins
|
AU2014232416B2
(en)
|
2013-03-15 |
2017-09-28 |
Xencor, Inc. |
Modulation of T Cells with Bispecific Antibodies and FC Fusions
|
WO2014140368A1
(en)
|
2013-03-15 |
2014-09-18 |
Amgen Research (Munich) Gmbh |
Antibody constructs for influenza m2 and cd3
|
AR095374A1
(es)
|
2013-03-15 |
2015-10-14 |
Amgen Res (Munich) Gmbh |
Moléculas de unión para bcma y cd3
|
US10106624B2
(en)
|
2013-03-15 |
2018-10-23 |
Xencor, Inc. |
Heterodimeric proteins
|
EP2968547B1
(en)
*
|
2013-03-15 |
2019-08-07 |
Memorial Sloan Kettering Cancer Center |
Multimerization technologies
|
ES2753950T3
(es)
|
2013-03-15 |
2020-04-15 |
Amgen Res Munich Gmbh |
Moléculas de unión monocatenarias que comprenden ABP del extremo N
|
US20140302037A1
(en)
*
|
2013-03-15 |
2014-10-09 |
Amgen Inc. |
BISPECIFIC-Fc MOLECULES
|
US9561291B2
(en)
*
|
2013-03-15 |
2017-02-07 |
Imre Kovesdi |
Methods of targeting T-cells to tumors
|
US10519242B2
(en)
|
2013-03-15 |
2019-12-31 |
Xencor, Inc. |
Targeting regulatory T cells with heterodimeric proteins
|
CA2907181C
(en)
|
2013-03-15 |
2023-10-17 |
Viktor Roschke |
Multivalent and monovalent multispecific complexes and their uses
|
CN107460201A
(zh)
*
|
2013-05-08 |
2017-12-12 |
科济生物医药(上海)有限公司 |
编码gpc‑3嵌合抗原受体蛋白的核酸及表达gpc‑3嵌合抗原受体蛋白的t淋巴细胞
|
EP3415534A1
(en)
*
|
2013-05-10 |
2018-12-19 |
Numab Therapeutics AG |
Bispecific constructs and their use in the treatment of various diseases
|
TR201904121T4
(tr)
*
|
2013-07-09 |
2019-04-22 |
The Government Of The United States As Represented By The Secretary Of The Dept Of Health And Human |
İnsan bispesifik egfrviii antikoru birleştirme molekülleri.
|
US11253606B2
(en)
|
2013-07-23 |
2022-02-22 |
Immunomedics, Inc. |
Combining anti-HLA-DR or anti-Trop-2 antibodies with microtubule inhibitors, PARP inhibitors, Bruton kinase inhibitors or phosphoinositide 3-kinase inhibitors significantly improves therapeutic outcome in cancer
|
CN104342453A
(zh)
*
|
2013-08-06 |
2015-02-11 |
深圳先进技术研究院 |
含基因工程抗体基因表达盒的微环dna重组母质粒、含该表达盒的微环dna及应用
|
US10745475B2
(en)
|
2013-08-30 |
2020-08-18 |
Takeda Gmbh |
Antibodies neutralizing GM-CSF for use in the treatment of rheumatoid arthritis or as analgesics
|
AR097648A1
(es)
|
2013-09-13 |
2016-04-06 |
Amgen Inc |
Combinación de factores epigenéticos y compuestos biespecíficos que tienen como diana cd33 y cd3 en el tratamiento de leucemia mieloide
|
MX2016003744A
(es)
|
2013-10-11 |
2016-08-11 |
Us Health |
Anticuerpos tem8 y su uso.
|
CN104623637A
(zh)
|
2013-11-07 |
2015-05-20 |
健能隆医药技术(上海)有限公司 |
Il-22二聚体在制备静脉注射药物中的应用
|
WO2015103549A1
(en)
|
2014-01-03 |
2015-07-09 |
The United States Of America, As Represented By The Secretary Department Of Health And Human Services |
Neutralizing antibodies to hiv-1 env and their use
|
AU2015219495B2
(en)
*
|
2014-02-21 |
2019-11-21 |
Ibc Pharmaceuticals, Inc. |
Disease therapy by inducing immune response to Trop-2 expressing cells
|
CN106029098A
(zh)
|
2014-02-25 |
2016-10-12 |
免疫医疗公司 |
人源化rfb4抗cd22抗体
|
TWI754319B
(zh)
|
2014-03-19 |
2022-02-01 |
美商再生元醫藥公司 |
用於腫瘤治療之方法及抗體組成物
|
KR102497443B1
(ko)
|
2014-03-28 |
2023-02-08 |
젠코어 인코포레이티드 |
Cd38 및 cd3에 결합하는 이중특이적 항체
|
RU2577226C2
(ru)
*
|
2014-04-10 |
2016-03-10 |
Общество с ограниченной ответственностью, "Международный биотехнологический центр "Генериум" ("МБЦ "Генериум") |
Способ получения биспецифических антител против cd3*cd19 формата флексибоди в клетках млекопитающих
|
RU2568910C2
(ru)
*
|
2014-04-18 |
2015-11-20 |
Общество с ограниченной ответственностью "Международный биотехнологический центр "Генериум" ("МБЦ "Генериум") |
Фармацевтические композиции на основе флексибоди против cd3*cd19 для лечения в-клеточных заболеваний
|
CN105017422A
(zh)
*
|
2014-04-30 |
2015-11-04 |
山东百因制药技术有限公司 |
一种抗cd3/抗cd19双特异性抗体及其应用
|
BR112016025126B1
(pt)
|
2014-05-07 |
2024-02-15 |
Takeda Pharmaceutical Company Limited |
Composição aquosa compreendendo anticorpo neutralizante de gmcsf, e uso da mesma
|
WO2015172341A1
(zh)
*
|
2014-05-14 |
2015-11-19 |
上海市肿瘤研究所 |
针对磷脂酰肌醇蛋白多糖-3和t细胞抗原的双特异性抗体
|
EP2947460A1
(en)
|
2014-05-22 |
2015-11-25 |
Medizinische Universität Wien |
Personalized therapy of inflammation-associated cancer using methods of assessing the susceptibility of a subject to the treatment with EGFR inhibitors/antagonists
|
LT3149480T
(lt)
|
2014-05-30 |
2019-04-25 |
Amgen Research (Munich) Gmbh |
B ląstelių pirmtakų ūmia limfoblastine leukemija (all) sergančių pacientų rizikos stratifikacijos būdas
|
BR112016030740A2
(pt)
|
2014-07-01 |
2018-02-20 |
Pfizer Inc. |
diacorpos heterodiméricos biespecíficos e seus usos
|
BR112017001579A2
(pt)
|
2014-07-25 |
2017-11-21 |
Cytomx Therapeutics Inc |
anticorpos anti-cd3, anticorpos anti-cd3 ativáveis, anticorpos anti-cd3 multiespecíficos, anticorpos anti-cd3 ativáveis multiespecíficos e métodos de uso dos mesmos
|
WO2016016415A1
(en)
|
2014-07-31 |
2016-02-04 |
Amgen Research (Munich) Gmbh |
Bispecific single chain antibody construct with enhanced tissue distribution
|
AR101669A1
(es)
|
2014-07-31 |
2017-01-04 |
Amgen Res (Munich) Gmbh |
Constructos de anticuerpos para cdh19 y cd3
|
TW201609812A
(zh)
|
2014-07-31 |
2016-03-16 |
安美基研究(慕尼黑)公司 |
最佳化之跨物種特異性雙特異性單鏈抗體構築體
|
WO2016030510A1
(en)
|
2014-08-28 |
2016-03-03 |
Medizinische Universität Wien |
Heteroaromatic chalcone derivatives and their medical use
|
EP3875481A1
(en)
|
2014-11-14 |
2021-09-08 |
The U.S.A. as represented by the Secretary, Department of Health and Human Services |
Neutralizing antibodies to ebola virus glycoprotein and their use
|
EP3699198A1
(en)
|
2014-11-17 |
2020-08-26 |
Regeneron Pharmaceuticals, Inc. |
Methods for tumor treatment using cd3xcd20 bispecific antibody
|
PE20171103A1
(es)
|
2014-11-26 |
2017-08-07 |
Xencor Inc |
Anticuerpos heterodimericos que se unen a cd3 y cd38
|
US10259887B2
(en)
|
2014-11-26 |
2019-04-16 |
Xencor, Inc. |
Heterodimeric antibodies that bind CD3 and tumor antigens
|
CA2967426A1
(en)
|
2014-11-26 |
2016-06-02 |
Xencor, Inc. |
Heterodimeric antibodies that bind cd3 and tumor antigens
|
EP3029067A1
(en)
|
2014-12-01 |
2016-06-08 |
Deutsches Krebsforschungszentrum |
Use of blocking-reagents for reducing unspecific T cell-activation
|
US20160168237A1
(en)
|
2014-12-12 |
2016-06-16 |
Alexion Pharmaceuticals, Inc. |
Method for treating a complement mediated disorder caused by an infectious agent in a patient
|
US10428155B2
(en)
|
2014-12-22 |
2019-10-01 |
Xencor, Inc. |
Trispecific antibodies
|
EP4039710A3
(en)
|
2015-01-23 |
2022-10-19 |
Sanofi |
Anti-cd3 antibodies, anti-cd123 antibodies and bispecific antibodies specifically binding to cd3 and/or cd123
|
WO2016135140A1
(en)
|
2015-02-23 |
2016-09-01 |
Cemm - Forschungszentrum Für Molekulare Medizin Gmbh |
4-aminoquinazoline derivatives as mth1 inhibitors for the therapy of cancer
|
WO2016135137A1
(en)
|
2015-02-23 |
2016-09-01 |
Cemm - Forschungszentrum Für Molekulare Medizin Gmbh |
Substituted 4-(phenylamino)quinoline derivatives as mth1 inhibitors for the therapy of cancer
|
BR112017017825A2
(pt)
|
2015-02-23 |
2018-04-10 |
Seagull Therapeutics Sas |
semaforinas 3 não naturais e seu uso médico
|
WO2016135138A1
(en)
|
2015-02-23 |
2016-09-01 |
Cemm - Forschungszentrum Für Molekulare Medizin Gmbh |
Oxoquinoline derivatives as mth1 inhibitors for the therapy of cancer
|
WO2016135139A1
(en)
|
2015-02-23 |
2016-09-01 |
Cemm - Forschungszentrum Für Molekulare Medizin Gmbh |
2,3-dihydrocyclopenta[b]quinoline derivatives as mth1 inhibitors for the therapy of cancer
|
CA2977687C
(en)
|
2015-02-24 |
2024-02-13 |
Hwai Wen Chang |
Conditionally active proteins
|
KR20170140180A
(ko)
|
2015-02-24 |
2017-12-20 |
더 유나이티드 스테이츠 오브 어메리카, 애즈 리프리젠티드 바이 더 세크러테리, 디파트먼트 오브 헬쓰 앤드 휴먼 서비씨즈 |
중동 호흡기 증후군 코로나 바이러스 면역원, 항체 및 그 용도
|
US10227411B2
(en)
|
2015-03-05 |
2019-03-12 |
Xencor, Inc. |
Modulation of T cells with bispecific antibodies and FC fusions
|
EP3064507A1
(en)
|
2015-03-06 |
2016-09-07 |
Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts |
Fusion proteins comprising a binding protein and an interleukin-15 polypeptide having a reduced affinity for IL15ra and therapeutic uses thereof
|
SI3271389T1
(sl)
|
2015-03-20 |
2020-09-30 |
The United States Of America, As Represented By The Secretary Department Of Health And Human Services |
Nevtralizirajoča protitelesa proti GP120 in njihova uporaba
|
WO2016164558A1
(en)
*
|
2015-04-07 |
2016-10-13 |
Children's Medical Center Corporation |
Methods and compositions relating to an embryonic stem cell-based tumor model
|
MX2017013348A
(es)
|
2015-04-17 |
2018-08-01 |
Amgen Res Munich Gmbh |
Construcciones de anticuerpos biespecificos contra cdh3 y cd3.
|
CN107428837A
(zh)
|
2015-04-22 |
2017-12-01 |
免疫医疗公司 |
循环trop‑2阳性癌细胞的分离、检测、诊断和/或鉴定
|
EP3285753A1
(en)
|
2015-04-22 |
2018-02-28 |
CeMM - Forschungszentrum für Molekulare Medizin GmbH |
Combination of an antiandrogen with a vitamin k antagonist or with a gamma -glutamyl carboxylase inhibitor for the therapy of androgen receptor positive cancer
|
RS59376B1
(sr)
|
2015-05-13 |
2019-11-29 |
Ablynx Nv |
Polipeptidi koji regrutuju t-ćelije na bazi tcr-alfa/beta reaktivnosti
|
EP3294319B1
(en)
|
2015-05-13 |
2024-04-24 |
Ablynx NV |
T cell recruiting polypeptides based on cd3 reactivity
|
EP3302555A4
(en)
|
2015-05-29 |
2018-07-11 |
Amphivena Therapeutics, Inc. |
Methods of using bispecific cd33 and cd3 binding proteins
|
WO2016196975A1
(en)
|
2015-06-03 |
2016-12-08 |
The United States Of America, As Represented By The Secretary Department Of Health & Human Services |
Neutralizing antibodies to hiv-1 env and their use
|
US10195175B2
(en)
|
2015-06-25 |
2019-02-05 |
Immunomedics, Inc. |
Synergistic effect of anti-Trop-2 antibody-drug conjugate in combination therapy for triple-negative breast cancer when used with microtubule inhibitors or PARP inhibitors
|
CN106349391A
(zh)
*
|
2015-07-17 |
2017-01-25 |
中国科学院深圳先进技术研究院 |
Hbv特异性双靶向抗体及其制备方法和应用、含该双靶向抗体表达盒的微环dna及应用
|
TW202346349A
(zh)
|
2015-07-31 |
2023-12-01 |
德商安美基研究(慕尼黑)公司 |
Dll3及cd3抗體構築體
|
TWI796283B
(zh)
|
2015-07-31 |
2023-03-21 |
德商安美基研究(慕尼黑)公司 |
Msln及cd3抗體構築體
|
TWI717375B
(zh)
|
2015-07-31 |
2021-02-01 |
德商安美基研究(慕尼黑)公司 |
Cd70及cd3抗體構築體
|
TWI744242B
(zh)
|
2015-07-31 |
2021-11-01 |
德商安美基研究(慕尼黑)公司 |
Egfrviii及cd3抗體構築體
|
TWI829617B
(zh)
|
2015-07-31 |
2024-01-21 |
德商安美基研究(慕尼黑)公司 |
Flt3及cd3抗體構築體
|
JO3620B1
(ar)
|
2015-08-05 |
2020-08-27 |
Amgen Res Munich Gmbh |
مثبطات نقطة فحص مناعية للاستخدام في علاج سرطانات محمولة عبر الدم
|
WO2017040344A2
(en)
|
2015-08-28 |
2017-03-09 |
Amunix Operating Inc. |
Chimeric polypeptide assembly and methods of making and using the same
|
WO2017044811A1
(en)
|
2015-09-11 |
2017-03-16 |
Bruce Andrien |
Recombinant glycosylated eculizumab and eculizumab variants
|
MA44909A
(fr)
|
2015-09-15 |
2018-07-25 |
Acerta Pharma Bv |
Association thérapeutique d'un inhibiteur du cd19 et d'un inhibiteur de la btk
|
AR106188A1
(es)
|
2015-10-01 |
2017-12-20 |
Hoffmann La Roche |
Anticuerpos anti-cd19 humano humanizados y métodos de utilización
|
CN108026177B
(zh)
|
2015-10-02 |
2021-11-26 |
豪夫迈·罗氏有限公司 |
双特异性抗cd19xcd3 t细胞活化性抗原结合分子
|
EP3359566A1
(en)
|
2015-10-07 |
2018-08-15 |
Alexion Pharmaceuticals, Inc. |
A method for treating age-related macular degeneration in a patient
|
US10392441B2
(en)
|
2015-10-07 |
2019-08-27 |
United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
IL-7R-alpha specific antibodies for treating acute lymphoblastic leukemia
|
US11472876B2
(en)
|
2015-11-02 |
2022-10-18 |
Bioatla, Inc. |
Conditionally active polypeptides
|
EP4011911A1
(en)
|
2015-11-03 |
2022-06-15 |
The United States of America as represented by The Secretary Department of Health and Human Services |
Neutralizing antibodies to hiv-1 gp41 and their use
|
CN105296421B
(zh)
*
|
2015-11-24 |
2019-01-29 |
高岱清 |
一种双特异性抗体活化的t细胞及制备方法与应用
|
RU2651776C2
(ru)
*
|
2015-12-01 |
2018-04-23 |
Общество с ограниченной ответственностью "Международный биотехнологический центр "Генериум" ("МБЦ "Генериум") |
Биспецифические антитела против cd3*cd19
|
CN108699136B
(zh)
|
2015-12-07 |
2022-03-18 |
Xencor股份有限公司 |
结合cd3和psma的异二聚抗体
|
IL259864B
(en)
|
2015-12-09 |
2022-07-01 |
Univ Wien Med |
Monomaleimide-functionalized platinum compounds for cancer therapy
|
SG11201804839WA
(en)
|
2015-12-14 |
2018-07-30 |
Macrogenics Inc |
Bispecific molecules having immunoreactivity with pd-1 and ctla-4, and methods of use thereof
|
CN114716557A
(zh)
|
2016-02-03 |
2022-07-08 |
安进研发(慕尼黑)股份有限公司 |
Psma和cd3双特异性t细胞接合抗体构建体
|
EA039859B1
(ru)
|
2016-02-03 |
2022-03-21 |
Эмджен Рисерч (Мюник) Гмбх |
Биспецифические конструкты антител, связывающие egfrviii и cd3
|
MA43955B1
(fr)
|
2016-02-03 |
2022-02-28 |
Amgen Inc |
Anticorps anti-bcma et anti-cd3 bispécifiques de format bite
|
US20170224837A1
(en)
|
2016-02-10 |
2017-08-10 |
Immunomedics, Inc. |
Combination of abcg2 inhibitors with sacituzumab govitecan (immu-132) overcomes resistance to sn-38 in trop-2 expressing cancers
|
MX2018009870A
(es)
|
2016-02-15 |
2018-11-29 |
Cemm Forschungszentrum Fuer Molekulare Medizin Gmbh |
Inhibidores de taf1 para la terapia del cancer.
|
EP3216458A1
(en)
|
2016-03-07 |
2017-09-13 |
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. |
Modified vascular endothelial growth factor a (vegf-a) and its medical use
|
KR20230148844A
(ko)
|
2016-03-29 |
2023-10-25 |
유니버시티 오브 써던 캘리포니아 |
암을 표적하는 키메라 항원 수용체
|
WO2017167350A1
(en)
*
|
2016-03-30 |
2017-10-05 |
Horst Lindhofer |
Multispecific antibodies for use in the treatment of a neoplasm of the urinary tract
|
JP7038353B2
(ja)
*
|
2016-04-13 |
2022-03-18 |
ヴィヴィア バイオテック,エス.エル |
エクスビボのbite活性化t細胞
|
US11510966B2
(en)
|
2016-04-15 |
2022-11-29 |
Evive Biotechnology (Shanghai) Ltd |
Use of IL-22 in treating necrotizing enterocolitis
|
JOP20170091B1
(ar)
|
2016-04-19 |
2021-08-17 |
Amgen Res Munich Gmbh |
إعطاء تركيبة ثنائية النوعية ترتبط بـ cd33 وcd3 للاستخدام في طريقة لعلاج اللوكيميا النخاعية
|
WO2017189279A1
(en)
|
2016-04-27 |
2017-11-02 |
Immunomedics, Inc. |
Efficacy of anti-trop-2-sn-38 antibody drug conjugates for therapy of tumors relapsed/refractory to checkpoint inhibitors
|
WO2017192589A1
(en)
|
2016-05-02 |
2017-11-09 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Neutralizing antibodies to influenza ha and their use and identification
|
CN105906720A
(zh)
*
|
2016-05-16 |
2016-08-31 |
武汉汉密顿生物科技股份有限公司 |
靶向性嵌合抗原受体修饰的免疫细胞及其制备方法和应用
|
RU2022104399A
(ru)
|
2016-06-14 |
2022-05-05 |
Ксенкор, Инк. |
Биспецифические антитела-ингибиторы контрольных точек
|
US10669338B2
(en)
|
2016-06-17 |
2020-06-02 |
Immunomedics, Inc. |
Anti-PD-1 checkpoint inhibitor antibodies that block binding of PD-L1 to PD-1
|
AU2017290086A1
(en)
|
2016-06-28 |
2019-01-24 |
Xencor, Inc. |
Heterodimeric antibodies that bind somatostatin receptor 2
|
AU2017290828A1
(en)
|
2016-06-30 |
2019-01-24 |
Virogin Biotech Canada Ltd |
Pseudotyped oncolytic viral delivery of therapeutic polypeptides
|
TWI790206B
(zh)
|
2016-07-18 |
2023-01-21 |
法商賽諾菲公司 |
特異性結合至cd3和cd123的雙特異性抗體樣結合蛋白
|
JP6994018B2
(ja)
|
2016-07-26 |
2022-01-14 |
バイオマリン ファーマシューティカル インコーポレイテッド |
新規アデノ随伴ウイルスキャプシドタンパク質
|
US10793632B2
(en)
|
2016-08-30 |
2020-10-06 |
Xencor, Inc. |
Bispecific immunomodulatory antibodies that bind costimulatory and checkpoint receptors
|
WO2018049261A1
(en)
|
2016-09-09 |
2018-03-15 |
Icellhealth Consulting Llc |
Oncolytic virus expressing immune checkpoint modulators
|
WO2018057915A1
(en)
|
2016-09-23 |
2018-03-29 |
The Regents Of The University Of Michigan |
Engineered lymphocytes
|
CN110214148A
(zh)
|
2016-10-14 |
2019-09-06 |
Xencor股份有限公司 |
含有IL-15/IL-15Rα Fc融合蛋白和PD-1抗体片段的双特异性异源二聚体融合蛋白
|
EP3529618B1
(en)
|
2016-10-19 |
2020-12-02 |
Alexion Pharmaceuticals, Inc. |
A method of quantitating unbound c5 in a sample
|
AU2017359288A1
(en)
|
2016-11-14 |
2019-05-30 |
Cemm - Forschungszentrum Für Molekulare Medizin Gmbh |
Combination of a BRD4 inhibitor and an antifolate for the therapy of cancer
|
CA3043515A1
(en)
|
2016-11-16 |
2018-05-24 |
Ablynx Nv |
T cell recruiting polypeptides capable of binding cd123 and tcr alpha/beta
|
JP2020503015A
(ja)
*
|
2016-12-13 |
2020-01-30 |
カースゲン セラピューティクス リミテッドCarsgen Therapeutics Limited |
抗cd19のヒト化抗体及びcd19を標的とする免疫エフェクター細胞
|
CN108264557B
(zh)
*
|
2016-12-30 |
2021-08-24 |
惠和生物技术(上海)有限公司 |
一种结合cd3和t细胞负共刺激分子的双功能分子及其应用
|
CN108264566B
(zh)
*
|
2016-12-30 |
2021-05-14 |
惠和生物技术(上海)有限公司 |
一种融合抗cd3抗体结构域和t细胞正共刺激分子配体的双特异性分子及其应用
|
JOP20190189A1
(ar)
|
2017-02-02 |
2019-08-01 |
Amgen Res Munich Gmbh |
تركيبة صيدلانية ذات درجة حموضة منخفضة تتضمن بنيات جسم مضاد يستهدف الخلية t
|
CN110944651A
(zh)
|
2017-02-08 |
2020-03-31 |
蜻蜓疗法股份有限公司 |
用于自然杀伤细胞激活的多特异性结合蛋白及其治疗癌症的治疗性用途
|
WO2018148660A1
(en)
|
2017-02-10 |
2018-08-16 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Neutralizing antibodies to plasmodium falciparum circumsporozoite protein and their use
|
WO2018152496A1
(en)
|
2017-02-17 |
2018-08-23 |
The Usa, As Represented By The Secretary, Dept. Of Health And Human Services |
Compositions and methods for the diagnosis and treatment of zika virus infection
|
CA3054079A1
(en)
|
2017-02-20 |
2018-08-23 |
Dragonfly Therapeutics, Inc. |
Proteins binding her2, nkg2d and cd16
|
AU2018224094A1
(en)
|
2017-02-24 |
2019-09-19 |
Macrogenics, Inc. |
Bispecific binding molecules that are capable of binding CD137 and tumor antigens, and uses thereof
|
RU2758234C2
(ru)
|
2017-03-27 |
2021-10-26 |
Иммьюномедикс, Инк. |
ЛЕЧЕНИЕ ТРИЖДЫ НЕГАТИВНОГО РАКА МОЛОЧНОЙ ЖЕЛЕЗЫ, ХАРАКТЕРИЗУЮЩЕГОСЯ ЭКСПРЕССИЕЙ Trop-2, С ПОМОЩЬЮ САЦИТУЗУМАБА ГОВИТЕКАНА И ИНГИБИТОРА Rad51
|
CN108659112B
(zh)
*
|
2017-03-30 |
2021-01-26 |
上海市同济医院 |
一种非对称双特异性抗体
|
EP3606964A4
(en)
|
2017-04-03 |
2020-12-09 |
Immunomedics, Inc. |
SUBCUTANE ADMINISTRATION OF ANTIBODY DRUG CONJUGATES FOR CANCER THERAPY
|
EP4230649A3
(en)
|
2017-04-25 |
2023-10-25 |
The U.S.A. As Represented By The Secretary, Department Of Health And Human Services |
Antibodies and methods for the diagnosis and treatment of epstein barr virus infection
|
MY201065A
(en)
|
2017-04-26 |
2024-02-01 |
Eureka Therapeutics Inc |
Constructs specifically recognizing glypican 3 and uses thereof
|
CA3060856A1
(en)
|
2017-05-05 |
2018-11-08 |
Amgen Inc. |
Pharmaceutical composition comprising bispecific antibody constructs for improved storage and administration
|
WO2018224441A1
(en)
|
2017-06-05 |
2018-12-13 |
Numab Innovation Ag |
Novel anti-cd3 antibodies
|
JP7474193B2
(ja)
|
2017-06-25 |
2024-04-24 |
システィミューン, インク. |
多重特異性抗体とその作製及び使用方法
|
MA49517A
(fr)
|
2017-06-30 |
2020-05-06 |
Xencor Inc |
Protéines de fusion fc hétérodimères ciblées contenant il-15/il-15ra et domaines de liaison à l'antigène
|
WO2019018629A1
(en)
|
2017-07-19 |
2019-01-24 |
The Usa, As Represented By The Secretary, Dept. Of Health And Human Services |
ANTIBODIES AND METHODS FOR DIAGNOSING AND TREATING INFECTION WITH HEPATITIS B VIRUS
|
EP3661954B1
(en)
|
2017-08-03 |
2022-02-09 |
Amgen Inc. |
Interleukin-21 muteins and methods of treatment
|
AU2018328291B2
(en)
|
2017-09-08 |
2022-10-27 |
Takeda Pharmaceutical Company Limited |
Constrained conditionally activated binding proteins
|
ES2928576T3
(es)
|
2017-09-08 |
2022-11-21 |
Amgen Inc |
Inhibidores de KRAS G12C y métodos de uso de los mismos
|
MA50239A
(fr)
|
2017-09-15 |
2020-07-22 |
Amgen Inc |
Procédé de formulation pharmaceutique lyophilisée d'une protéine thérapeutique
|
CA3185107A1
(en)
|
2017-10-12 |
2019-04-18 |
Immunowake Inc. |
Vegfr-antibody light chain fusion protein
|
US20200262919A1
(en)
|
2017-10-13 |
2020-08-20 |
Merck Sharp & Dohme Corp. |
Compositions and methods for treating diffuse large b cell lymphoma
|
US11472889B2
(en)
|
2017-10-14 |
2022-10-18 |
Cytomx Therapeutics, Inc. |
Antibodies, activatable antibodies, bispecific antibodies, and bispecific activatable antibodies and methods of use thereof
|
CN107739410B
(zh)
*
|
2017-10-18 |
2021-07-30 |
南京鼓楼医院 |
CD3单链抗体-iRGD融合蛋白、制备及其作为抗肿瘤药物的应用
|
KR20200074201A
(ko)
|
2017-11-02 |
2020-06-24 |
바이엘 악티엔게젤샤프트 |
Alk-1 및 bmpr-2에 결합하는 이중특이적 항체
|
JP2021502100A
(ja)
|
2017-11-08 |
2021-01-28 |
ゼンコア インコーポレイテッド |
新規抗pd−1配列を用いた二重特異性および単一特異性抗体
|
US10981992B2
(en)
|
2017-11-08 |
2021-04-20 |
Xencor, Inc. |
Bispecific immunomodulatory antibodies that bind costimulatory and checkpoint receptors
|
BR112020011627A2
(pt)
|
2017-12-11 |
2020-11-17 |
Amgen Inc. |
processo de fabricação contínuo para produtos de anticorpos biespecíficos
|
AU2018385409A1
(en)
|
2017-12-12 |
2020-07-02 |
Macrogenics Inc. |
Bispecific CD 16-binding molecules and their use in the treatment of disease
|
JP2021506291A
(ja)
|
2017-12-19 |
2021-02-22 |
ゼンコア インコーポレイテッド |
改変されたil−2 fc融合タンパク質
|
UY38041A
(es)
|
2017-12-29 |
2019-06-28 |
Amgen Inc |
Construcción de anticuerpo biespecífico dirigida a muc17 y cd3
|
WO2019133847A1
(en)
|
2017-12-29 |
2019-07-04 |
Oncorus, Inc. |
Oncolytic viral delivery of therapeutic polypeptides
|
EP3724223A1
(en)
|
2018-01-02 |
2020-10-21 |
The United States of America, as represented by The Secretary, Department of Health and Human Services |
Neutralizing antibodies to ebola virus glycoprotein and their use
|
CN107987169B
(zh)
*
|
2018-01-05 |
2021-10-08 |
阿思科力(苏州)生物科技有限公司 |
一种以ROBO1为靶点的双特异性抗体scFv及其制备和应用
|
CR20210319A
(es)
|
2018-01-12 |
2021-07-27 |
Amgen Inc |
ANTICUERPOS ANTI-PD-1 Y MÉTODOS DE TRATAMIENTO (Div. 2020-330)
|
PE20220278A1
(es)
|
2018-02-08 |
2022-02-25 |
Dragonfly Therapeutics Inc |
Dominios variables de anticuerpos que se dirigen al receptor nkg2d
|
JP7337079B2
(ja)
|
2018-02-15 |
2023-09-01 |
マクロジェニクス,インコーポレーテッド |
変異型cd3結合ドメイン、及び疾患の治療のための併用療法におけるその使用
|
WO2019165122A1
(en)
|
2018-02-21 |
2019-08-29 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Neutralizing antibodies to hiv-1 env and their use
|
AU2019228128A1
(en)
|
2018-03-02 |
2020-09-03 |
Cdr-Life Ag |
Trispecific antigen binding proteins
|
WO2019177011A1
(ja)
*
|
2018-03-13 |
2019-09-19 |
国立大学法人大阪大学 |
腫瘍免疫賦活剤
|
US20190284288A1
(en)
|
2018-03-19 |
2019-09-19 |
The Regents Of The University Of Michigan |
Compositions and methods for t-cell and cytokine activation
|
CN112469477A
(zh)
|
2018-04-04 |
2021-03-09 |
Xencor股份有限公司 |
与成纤维细胞活化蛋白结合的异源二聚体抗体
|
EP3781599A1
(en)
|
2018-04-18 |
2021-02-24 |
Xencor, Inc. |
Pd-1 targeted heterodimeric fusion proteins containing il-15/il-15ra fc-fusion proteins and pd-1 antigen binding domains and uses thereof
|
CN112437777A
(zh)
|
2018-04-18 |
2021-03-02 |
Xencor股份有限公司 |
包含IL-15/IL-15RA Fc融合蛋白和TIM-3抗原结合结构域的靶向TIM-3的异源二聚体融合蛋白
|
WO2019207051A1
(en)
|
2018-04-25 |
2019-10-31 |
Università Degli Studi Di Torino |
Medical use of combinations of non-natural semaphorins 3 and antimetabolites
|
EP3788071A1
(en)
|
2018-05-02 |
2021-03-10 |
The United States Of America, As Represented By The Secretary, Department of Health and Human Services |
Antibodies and methods for the diagnosis, prevention, and treatment of epstein barr virus infection
|
SG11202010830WA
(en)
|
2018-05-09 |
2020-11-27 |
Biomarin Pharm Inc |
Methods of treating phenylketonuria
|
TW202005978A
(zh)
|
2018-05-14 |
2020-02-01 |
美商拜奧馬林製藥公司 |
新穎肝靶向腺相關病毒載體
|
EP3806888B1
(en)
|
2018-06-12 |
2024-01-31 |
Obsidian Therapeutics, Inc. |
Pde5 derived regulatory constructs and methods of use in immunotherapy
|
SG11202013138RA
(en)
|
2018-07-02 |
2021-01-28 |
Amgen Inc |
Anti-steap1 antigen-binding protein
|
TW202021616A
(zh)
|
2018-07-30 |
2020-06-16 |
美商安進公司 |
結合至cd33和cd3的雙特異性抗體構建體之延長投與
|
TW202019477A
(zh)
|
2018-07-31 |
2020-06-01 |
德商安美基研究(慕尼黑)公司 |
BCMAxCD3抗體構建體之給藥方案
|
MX2021001353A
(es)
|
2018-08-03 |
2021-04-13 |
Amgen Res Munich Gmbh |
Constructos de anticuerpos para cldn18.2 y cd3.
|
JP2021535142A
(ja)
|
2018-08-31 |
2021-12-16 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッドRegeneron Pharmaceuticals, Inc. |
Cd3/c20二重特異性抗体のサイトカイン放出症候群を軽減する投与戦略
|
US11066476B2
(en)
|
2018-09-14 |
2021-07-20 |
Shanghai tongji hospital |
Asymmetric bispecific antibody
|
CN110590955B
(zh)
*
|
2018-09-17 |
2021-05-18 |
北京盛诺基医药科技股份有限公司 |
一种双特异性抗体
|
MA53724A
(fr)
|
2018-09-24 |
2021-12-29 |
Amgen Inc |
Systèmes et procédés de dosage interventionnel
|
EP3856781A1
(en)
|
2018-09-28 |
2021-08-04 |
Amgen Inc. |
Antibodies against soluble bcma
|
US11358999B2
(en)
|
2018-10-03 |
2022-06-14 |
Xencor, Inc. |
IL-12 heterodimeric Fc-fusion proteins
|
US20210395298A1
(en)
|
2018-10-11 |
2021-12-23 |
Amgen Inc. |
Downstream processing of bispecific antibody constructs
|
CA3115296A1
(en)
|
2018-10-23 |
2020-04-30 |
Amgen Inc. |
Automatic calibration and automatic maintenance of raman spectroscopic models for real-time predictions
|
WO2020106886A1
(en)
|
2018-11-20 |
2020-05-28 |
Cornell University |
Macrocyclic complexes of radionuclides and their use in radiotherapy of cancer
|
WO2020132214A2
(en)
|
2018-12-20 |
2020-06-25 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Ebola virus glycoprotein-specific monoclonal antibodies and uses thereof
|
TW202043253A
(zh)
|
2019-01-28 |
2020-12-01 |
美商安進公司 |
藉由將藥物物質和藥物產品過程整體化的生物製劑製造之連續製造過程
|
WO2020172293A1
(en)
|
2019-02-20 |
2020-08-27 |
Amgen Inc. |
Methods of determining protein stability
|
CA3132185A1
(en)
|
2019-03-01 |
2020-09-10 |
Xencor, Inc. |
Heterodimeric antibodies that bind enpp3 and cd3
|
CN114390938A
(zh)
|
2019-03-05 |
2022-04-22 |
武田药品工业有限公司 |
受约束的条件性活化的结合蛋白
|
CA3133459A1
(en)
|
2019-03-27 |
2020-10-01 |
Amgen Inc. |
Methods of fingerprinting therapeutic proteins via a two-dimensional (2d) nuclear magnetic resonance technique at natural abundance for formulated biopharmaceutical products
|
EP3962948A1
(en)
|
2019-04-30 |
2022-03-09 |
Amgen Research (Munich) GmbH |
Means and methods of treating burkitt lymphoma or leukemia
|
WO2020227228A2
(en)
|
2019-05-03 |
2020-11-12 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Neutralizing antibodies to plasmodium falciparum circumsporozoite protein and their use
|
US20230085439A1
(en)
|
2019-05-21 |
2023-03-16 |
University Of Georgia Research Foundation, Inc. |
Antibodies that bind human metapneumovirus fusion protein and their use
|
JP2022535060A
(ja)
|
2019-06-07 |
2022-08-04 |
アムジエン・インコーポレーテツド |
選択的に切断可能なリンカーを有する二重特異性結合構築物
|
MX2021014644A
(es)
|
2019-06-13 |
2022-04-06 |
Amgen Inc |
Control de perfusion basado en biomasa automatizado en la fabricacion de productos biologicos.
|
CA3142833A1
(en)
|
2019-07-02 |
2021-01-07 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Monoclonal antibodies that bind egfrviii and their use
|
CN110623921B
(zh)
*
|
2019-08-15 |
2020-10-30 |
北京东方百泰生物科技股份有限公司 |
一种抗cd3和抗cd19的双特异性抗体注射制剂
|
RU2738802C1
(ru)
*
|
2019-08-21 |
2020-12-17 |
Общество с ограниченной ответственностью "Международный Биотехнологический Центр "Генериум" |
Определяющие комплементарность участки для связывания cd3 и содержащая их биспецифическая антигенсвязывающая молекула
|
GB201912681D0
(en)
|
2019-09-04 |
2019-10-16 |
Eth Zuerich |
Bispecific binding agent that binds to cd117/c-kit and cd3
|
WO2021050640A1
(en)
|
2019-09-10 |
2021-03-18 |
Amgen Inc. |
Purification method for bispecific antigen-binding polypeptides with enhanced protein l capture dynamic binding capacity
|
CA3151704A1
(en)
|
2019-10-02 |
2021-04-08 |
Domain Therapeutics |
Prostaglandin e2 (pge2) ep4 receptor antagonists
|
EP3808741A1
(en)
|
2019-10-16 |
2021-04-21 |
CeMM - Forschungszentrum für Molekulare Medizin GmbH |
Compounds for targeted degradation of carrier proteins and uses thereof
|
WO2021074418A1
(en)
|
2019-10-16 |
2021-04-22 |
Cemm - Forschungszentrum Für Molekulare Medizin Gmbh |
Carbazole-type cullin ring ubiquitin ligase compounds and uses thereof
|
IL292153A
(en)
|
2019-10-16 |
2022-06-01 |
Cemm Forschungszentrum Fur Molekulare Medizin Gmbh |
Oxazole and thiazole choline ubiquitin ligase ring compounds and uses thereof
|
EP4054590A1
(en)
|
2019-11-04 |
2022-09-14 |
Amgen Inc. |
Methods for treating leukemia
|
EP3819312A1
(en)
|
2019-11-10 |
2021-05-12 |
Amgen, Inc |
Dosing regimen for anti-dll3 agents
|
EP3819007A1
(en)
|
2019-11-11 |
2021-05-12 |
Amgen Research (Munich) GmbH |
Dosing regimen for anti-bcma agents
|
US20220396599A1
(en)
|
2019-11-13 |
2022-12-15 |
Amgen Inc. |
Method for Reduced Aggregate Formation in Downstream Processing of Bispecific Antigen-Binding Molecules
|
US20230093169A1
(en)
|
2020-01-22 |
2023-03-23 |
Amgen Research (Munch) Gmbh |
Combinations of antibody constructs and inhibitors of cytokine release syndrome and uses thereof
|
US20230348624A1
(en)
|
2020-01-30 |
2023-11-02 |
Umoja Biopharma, Inc. |
Bispecific transduction enhancer
|
WO2021158469A1
(en)
|
2020-02-03 |
2021-08-12 |
Amgen Inc. |
Multivariate bracketing approach for sterile filter validation
|
TW202140561A
(zh)
|
2020-02-14 |
2021-11-01 |
日商協和麒麟股份有限公司 |
與cd3結合之雙特異性抗體
|
KR20220148209A
(ko)
|
2020-02-28 |
2022-11-04 |
상하이 헨리우스 바이오테크, 인크. |
항cd137 작제물 및 그 용도
|
CN115151573A
(zh)
|
2020-02-28 |
2022-10-04 |
上海复宏汉霖生物技术股份有限公司 |
抗cd137构建体、多特异性抗体及其用途
|
US11896619B2
(en)
|
2020-03-10 |
2024-02-13 |
Massachusetts Institute Of Technology |
Compositions and methods for immunotherapy of NPM1c-positive cancer
|
WO2021183861A1
(en)
|
2020-03-12 |
2021-09-16 |
Amgen Inc. |
Method for treatment and prophylaxis of crs in patients comprising a combination of bispecifc antibodies binding to cds x cancer cell and tnfalpha or il-6 inhibitor
|
WO2021188851A1
(en)
|
2020-03-19 |
2021-09-23 |
Amgen Inc. |
Antibodies against mucin 17 and uses thereof
|
US11919956B2
(en)
|
2020-05-14 |
2024-03-05 |
Xencor, Inc. |
Heterodimeric antibodies that bind prostate specific membrane antigen (PSMA) and CD3
|
EP4153633A1
(en)
|
2020-05-19 |
2023-03-29 |
Amgen Inc. |
Mageb2 binding constructs
|
MX2022014902A
(es)
|
2020-05-29 |
2023-01-04 |
Amgen Inc |
Administracion mitigadora de efectos adversos de un constructo biespecifico que se une a cd33 y cd3.
|
CA3185858A1
(en)
|
2020-06-02 |
2021-12-09 |
Dynamicure Biotechnology Llc |
Anti-cd93 constructs and uses thereof
|
CN116529260A
(zh)
|
2020-06-02 |
2023-08-01 |
当康生物技术有限责任公司 |
抗cd93构建体及其用途
|
CA3184351A1
(en)
|
2020-06-04 |
2021-12-09 |
Amgen Inc. |
Bispecific binding constructs
|
CA3190328A1
(en)
|
2020-07-29 |
2022-02-03 |
Dynamicure Biotechnology Llc |
Anti-cd93 constructs and uses thereof
|
KR102607909B1
(ko)
|
2020-08-19 |
2023-12-01 |
젠코어 인코포레이티드 |
항-cd28 조성물
|
CN116322763A
(zh)
|
2020-08-27 |
2023-06-23 |
学校法人顺天堂 |
抗切断型突变calr-cd3双特异性抗体及医药组合物
|
EP4210748A1
(en)
|
2020-09-11 |
2023-07-19 |
Amgen Inc. |
Materials and methods to reduce protein aggregation
|
AU2021345124A1
(en)
|
2020-09-16 |
2023-03-30 |
Amgen Inc. |
Methods for administering therapeutic doses of bispecific T-cell engaging molecules for the treatment of cancer
|
WO2022060878A1
(en)
|
2020-09-16 |
2022-03-24 |
Amgen Inc. |
Methods for treating prostate cancer
|
JP2023545588A
(ja)
|
2020-10-16 |
2023-10-30 |
ツェーエムエム-フォルシュングスツェントルム フュア モレクラレ メディツィン ゲーエムベーハー |
ヘテロ環式カリンringユビキチンリガーゼ化合物及びその使用
|
BR112023008629A2
(pt)
|
2020-11-06 |
2023-10-03 |
Amgen Inc |
Construtos de polipeptídeos que se ligam seletivamente a cldn6 e cd3
|
CN116323671A
(zh)
|
2020-11-06 |
2023-06-23 |
安进公司 |
具有增加的选择性的多靶向性双特异性抗原结合分子
|
BR112023008670A2
(pt)
|
2020-11-06 |
2024-02-06 |
Amgen Inc |
Construtos polipeptídicos ligados à cd3
|
TW202233678A
(zh)
|
2020-11-06 |
2022-09-01 |
德商安美基研究(慕尼黑)公司 |
具有增強的剪切特徵的多肽
|
TW202233682A
(zh)
|
2020-11-10 |
2022-09-01 |
美商安進公司 |
用於投與BCMAxCD3結合分子之方法
|
EP4255931A1
(en)
|
2020-12-03 |
2023-10-11 |
Amgen Inc. |
Immunoglobuline constructs with multiple binding domains
|
WO2022132904A1
(en)
|
2020-12-17 |
2022-06-23 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Human monoclonal antibodies targeting sars-cov-2
|
MX2023007299A
(es)
|
2020-12-18 |
2023-07-04 |
Ablynx Nv |
Polipeptidos de reclutamiento de celulas t basados en la reactividad de tcr alfa/beta.
|
JP2024504390A
(ja)
|
2021-01-22 |
2024-01-31 |
バイワンキュア セラピューティクス, インコーポレイテッド |
抗her-2/trop-2構築物及びその使用
|
KR20230157315A
(ko)
|
2021-01-28 |
2023-11-16 |
리제너론 파마슈티칼스 인코포레이티드 |
사이토카인 방출 증후군을 치료하기 위한 조성물 및 방법
|
US20240117019A1
(en)
|
2021-02-09 |
2024-04-11 |
University Of Georgia Research Foundation, Inc. |
Human monoclonal antibodies against pneumococcal antigens
|
IL304955A
(en)
|
2021-02-09 |
2023-10-01 |
Us Health |
Antibodies targeting the spike protein of a coronavirus
|
WO2022171121A1
(zh)
|
2021-02-10 |
2022-08-18 |
同润生物医药(上海)有限公司 |
***的方法和组合
|
CA3212665A1
(en)
|
2021-03-09 |
2022-09-15 |
Xencor, Inc. |
Heterodimeric antibodies that bind cd3 and cldn6
|
KR20230154311A
(ko)
|
2021-03-10 |
2023-11-07 |
젠코어 인코포레이티드 |
Cd3 및 gpc3에 결합하는 이종이량체 항체
|
WO2022191971A1
(en)
|
2021-03-10 |
2022-09-15 |
Amgen Inc. |
Parallel chromatography systems and methods
|
JP2024509877A
(ja)
|
2021-03-10 |
2024-03-05 |
アムジエン・インコーポレーテツド |
組換えタンパク質の精製方法
|
EP4314049A1
(en)
|
2021-03-25 |
2024-02-07 |
Dynamicure Biotechnology LLC |
Anti-igfbp7 constructs and uses thereof
|
CN112794916B
(zh)
*
|
2021-04-08 |
2021-08-10 |
正大天晴药业集团南京顺欣制药有限公司 |
三特异性抗原结合构建体及构建方法和应用
|
CN117279947A
(zh)
|
2021-05-06 |
2023-12-22 |
安进研发(慕尼黑)股份有限公司 |
用于在增殖性疾病中使用的靶向cd20和cd22的抗原结合分子
|
EP4355785A1
(en)
|
2021-06-17 |
2024-04-24 |
Amberstone Biosciences, Inc. |
Anti-cd3 constructs and uses thereof
|
WO2023044272A1
(en)
|
2021-09-17 |
2023-03-23 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Synthetic humanized llama nanobody library and use thereof to identify sars-cov-2 neutralizing antibodies
|
CA3235228A1
(en)
|
2021-10-15 |
2023-04-20 |
Amgen Research (Munich) Gmbh |
Subcutaneous administration of cd19-binding t cell engagers
|
TW202326113A
(zh)
|
2021-10-27 |
2023-07-01 |
美商安進公司 |
使用光譜學進行的基於深度學習的預測
|
EP4180035A1
(en)
|
2021-11-15 |
2023-05-17 |
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. |
Novel beta-lactone inhibitors of hydrolytic enzymes and their medical and non medical uses
|
WO2023110918A1
(en)
|
2021-12-14 |
2023-06-22 |
Cdr-Life Ag |
Dual mhc-targeting t cell engager
|
WO2023154824A1
(en)
|
2022-02-10 |
2023-08-17 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Human monoclonal antibodies that broadly target coronaviruses
|
WO2023164474A1
(en)
|
2022-02-23 |
2023-08-31 |
Amgen Inc. |
Cancer treatment targeting dll3
|
WO2023192881A1
(en)
|
2022-03-28 |
2023-10-05 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Neutralizing antibodies to hiv-1 env and their use
|
WO2023201226A1
(en)
|
2022-04-11 |
2023-10-19 |
Regeneron Pharmaceuticals, Inc. |
Compositions and methods for universal tumor cell killing
|
WO2023203172A1
(en)
|
2022-04-20 |
2023-10-26 |
Proxygen Gmbh |
Heterocyclic cullin ring ubiquitin ligase compounds and uses thereof
|
TW202346368A
(zh)
|
2022-05-12 |
2023-12-01 |
德商安美基研究(慕尼黑)公司 |
具有增加的選擇性的多鏈多靶向性雙特異性抗原結合分子
|
US20240117062A1
(en)
|
2022-05-27 |
2024-04-11 |
Sanofi |
Anti-bcma antibodies
|
US20240109965A1
(en)
|
2022-06-14 |
2024-04-04 |
Ablynx N.V. |
Immunoglobulin single variable domains targeting t cell receptor
|
WO2024030829A1
(en)
|
2022-08-01 |
2024-02-08 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Monoclonal antibodies that bind to the underside of influenza viral neuraminidase
|
WO2024054822A1
(en)
|
2022-09-07 |
2024-03-14 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Engineered sars-cov-2 antibodies with increased neutralization breadth
|
US20240091262A1
(en)
|
2022-09-14 |
2024-03-21 |
Cdr-Life Ag |
Mage-a4 peptide dual t cell engagers
|
WO2024059675A2
(en)
|
2022-09-14 |
2024-03-21 |
Amgen Inc. |
Bispecific molecule stabilizing composition
|
WO2024064826A1
(en)
|
2022-09-22 |
2024-03-28 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Neutralizing antibodies to plasmodium falciparum circumsporozoite protein and their use
|
WO2024068944A1
(en)
|
2022-09-30 |
2024-04-04 |
Sanofi |
Anti-cd28 antibodies
|
WO2024077044A1
(en)
|
2022-10-05 |
2024-04-11 |
Amgen Inc. |
Combination therapies comprising t-cell redirecting therapies and agonistic anti-il-2r antibodies or fragments thereof
|
WO2024092033A1
(en)
|
2022-10-26 |
2024-05-02 |
Amgen Inc. |
Multispecific molecules for clearance of immunoglobulins in the treatment of autoantibody-induced diseases
|