US4783443A
(en)
|
1986-03-03 |
1988-11-08 |
The University Of Chicago |
Amino acyl cephalosporin derivatives
|
US5844092A
(en)
|
1994-03-18 |
1998-12-01 |
Genentech, Inc. |
Human TRK receptors and neurotrophic factor inhibitors
|
US5877016A
(en)
|
1994-03-18 |
1999-03-02 |
Genentech, Inc. |
Human trk receptors and neurotrophic factor inhibitors
|
US6677135B1
(en)
|
1996-05-08 |
2004-01-13 |
Biogen, Inc. |
Ret ligand (RetL) for stimulating neutral and renal growth
|
CN1163509C
(zh)
|
1996-05-08 |
2004-08-25 |
拜奥根有限公司 |
刺激神经和肾生长的RET配体(RetL)
|
US6682921B1
(en)
|
1996-08-21 |
2004-01-27 |
New York University |
Crystals of the tyrosine kinase domain of non-insulin receptor tyrosine kinases
|
US6531152B1
(en)
|
1998-09-30 |
2003-03-11 |
Dexcel Pharma Technologies Ltd. |
Immediate release gastrointestinal drug delivery system
|
AU7103900A
(en)
|
1999-09-01 |
2001-03-26 |
Biogen, Inc. |
Ret ligand 5 (retl5) compositions and uses thereof
|
FI20000403A0
(fi)
|
2000-02-22 |
2000-02-22 |
Hannu Sariola |
GDNF perhesukuisten yhdisteiden käyttö kivessyövän hoitoon tarkoitettujen tuotteiden valmistamiseksi
|
DE60140252D1
(de)
|
2000-06-22 |
2009-12-03 |
Genentech Inc |
Agonistische monoklonale antikörper gegen trkc
|
AU2002334355A1
(en)
|
2001-09-06 |
2003-03-18 |
Prochon Biotech Ltd. |
Protein tyrosine kinase inhibitors
|
US7466344B2
(en)
|
2002-06-07 |
2008-12-16 |
Scimeasure Analytical Systems, Inc. |
High-speed low noise CCD controller
|
ITMI20021620A1
(it)
|
2002-07-23 |
2004-01-23 |
Novuspharma Spa |
Composto ad ativita' antitumorale
|
EP1526854A1
(en)
|
2002-07-24 |
2005-05-04 |
University Of Cincinnati |
4-4(methylpiperazin-1-ylmethyl)-n- 4-methyl-3-(pyridin-3-yl)pyrimidin-2-ylamino)phenyl -benzamide for treating mutated-ret kinase associated diseases
|
DE602004021472D1
(en)
|
2003-02-20 |
2009-07-23 |
Smithkline Beecham Corp |
Pyrimiidinverbindungen
|
US20090143399A1
(en)
|
2003-10-14 |
2009-06-04 |
Arizona Board Of Regents On Behalf Of The University Of Arizona |
Protein Kinase Inhibitors
|
US7169918B2
(en)
|
2003-10-27 |
2007-01-30 |
Genelabs Technologies, Inc. |
Methods for preparing 7-(2′-substituted-β-D-ribofuranosyl)-4-(NR2R3)-5-(substituted ethyn-1-yl)-pyrrolo[2,3-d]pyrimidine derivatives
|
MY141220A
(en)
|
2003-11-17 |
2010-03-31 |
Astrazeneca Ab |
Pyrazole derivatives as inhibitors of receptor tyrosine kinases
|
EP1687305B1
(en)
|
2003-11-21 |
2008-07-09 |
Novartis AG |
1h-imidazoquinoline derivatives as protein kinase inhibitors
|
CA2546673A1
(en)
|
2003-11-28 |
2005-06-09 |
Novartis Ag |
Diaryl urea derivatives in the treatment of protein kinase dependent diseases
|
SI1696920T1
(sl)
|
2003-12-19 |
2015-02-27 |
Plexxikon Inc. |
Spojine in postopki za razvoj modulatorjev ret
|
GB0330043D0
(en)
|
2003-12-24 |
2004-01-28 |
Pharmacia Italia Spa |
Pyrrolo [2,3-b] pyridine derivatives active as kinase inhibitors process for their preparation and pharmaceutical compositions comprising them
|
GB0330042D0
(en)
|
2003-12-24 |
2004-01-28 |
Pharmacia Italia Spa |
Pyrrolo [2,3-b] pyridine derivatives active as kinase inhibitors process for their preparation and pharmaceutical compositions them
|
WO2005068424A1
(en)
|
2004-01-20 |
2005-07-28 |
Cell Therapeutics Europe S.R.L. |
Indolinone derivatives as receptor tyrosine kinase ihibitors
|
US20050222171A1
(en)
|
2004-01-22 |
2005-10-06 |
Guido Bold |
Organic compounds
|
PE20051089A1
(es)
|
2004-01-22 |
2006-01-25 |
Novartis Ag |
Derivados de pirazolo [1,5-a] pirimidin-7-il-amina como inhibidores de quinasa de proteina
|
WO2005099363A2
(en)
|
2004-03-26 |
2005-10-27 |
Whitehead Institute For Biomedical Research |
Methods of diagnosing, preventing and treating cancer metastasis
|
GB0512324D0
(en)
|
2005-06-16 |
2005-07-27 |
Novartis Ag |
Organic compounds
|
CN101052629A
(zh)
*
|
2004-08-02 |
2007-10-10 |
Osi制药公司 |
芳基-氨基取代的吡咯并嘧啶多激酶抑制化合物
|
CA2575808A1
(en)
|
2004-08-02 |
2006-02-16 |
Osi Pharmaceuticals, Inc. |
Aryl-amino substituted pyrrolopyrimidine multi-kinase inhibiting compounds
|
PE20060664A1
(es)
|
2004-09-15 |
2006-08-04 |
Novartis Ag |
Amidas biciclicas como inhibidores de cinasa
|
US7855205B2
(en)
|
2004-10-29 |
2010-12-21 |
Janssen Pharmaceutica Nv |
Pyrimidinyl substituted fused-pyrrolyl compounds useful in treating kinase disorders
|
DE102005003687A1
(de)
|
2005-01-26 |
2006-07-27 |
Sphingo Tec Gmbh |
Immunoassay zur Bestimmung der Freisetzung von Neurotensin in die Zirkulation
|
GB0501999D0
(en)
|
2005-02-01 |
2005-03-09 |
Sentinel Oncology Ltd |
Pharmaceutical compounds
|
CN101257948A
(zh)
|
2005-02-18 |
2008-09-03 |
阿特努奥恩公司 |
嘧啶并二氮䓬衍生物及吲哚并蝶啶化合物
|
GB0507575D0
(en)
|
2005-04-14 |
2005-05-18 |
Novartis Ag |
Organic compounds
|
CA2604787A1
(en)
|
2005-04-15 |
2006-10-26 |
Cylene Pharmaceuticals, Inc. |
Quinobenzoxazine analogs and methods of using thereof
|
NZ564317A
(en)
|
2005-05-16 |
2011-01-28 |
Astrazeneca Ab |
Pyrazolylaminopyrimidine derivatives useful as tyrosine kinase inhibitors
|
US20100047777A1
(en)
|
2005-05-26 |
2010-02-25 |
The Johns Hopkins University |
Methods for identifying mutations in coding and non-coding dna
|
WO2006130673A1
(en)
|
2005-05-31 |
2006-12-07 |
Janssen Pharmaceutica, N.V. |
3-benzoimidazolyl-pyrazolopyridines useful in treating kinase disorders
|
EP1896462A2
(en)
|
2005-05-31 |
2008-03-12 |
The Pfahl Family Trust (Dated 9 July 1996) |
Substituted biarylheterocycle derivatives as protein kinase inhibitors for the treatment of cancer and other diseases
|
ITRM20050290A1
(it)
|
2005-06-07 |
2006-12-08 |
Lay Line Genomics Spa |
Uso di molecole in grado di inibire il legame tra ngf e il suo recettore trka come analgesici ad effetto prolungato.
|
PE20070100A1
(es)
|
2005-06-22 |
2007-03-10 |
Plexxikon Inc |
DERIVADOS DE PIRROLO[2,3-b]PIRIDINA COMO MODULADORES DE QUINASAS
|
GB0515026D0
(en)
|
2005-07-21 |
2005-08-31 |
Novartis Ag |
Organic compounds
|
AU2006284096B2
(en)
|
2005-08-25 |
2012-03-29 |
Avro Life Sciences, Inc. |
Polymer conjugates of K-252a and derivatives thereof
|
JP2009519218A
(ja)
|
2005-11-03 |
2009-05-14 |
エスジーエックス ファーマシューティカルズ、インコーポレイテッド |
ピリミジニル−チオフェンキナーゼモジュレータ
|
US20070149523A1
(en)
|
2005-11-14 |
2007-06-28 |
Jan Ehlert |
Thiazole Analogues and Uses Thereof
|
EP1785420A1
(en)
|
2005-11-14 |
2007-05-16 |
4Sc Ag |
Thiazole analogues and uses thereof
|
WO2007057397A1
(en)
|
2005-11-15 |
2007-05-24 |
Boehringer Ingelheim International Gmbh |
Treatment of cancer
|
WO2007057399A2
(en)
|
2005-11-15 |
2007-05-24 |
Boehringer Ingelheim International Gmbh |
Treatment of cancer with indole derivatives
|
GB0524436D0
(en)
|
2005-11-30 |
2006-01-11 |
Novartis Ag |
Organic compounds
|
AU2006322187A1
(en)
|
2005-12-08 |
2007-06-14 |
Novartis Ag |
Pyrazolo[1,5-a]pyridine-3-carboxylic acids as EphB and VEGFR2 kinase inhibitors
|
US8399442B2
(en)
|
2005-12-30 |
2013-03-19 |
Astex Therapeutics Limited |
Pharmaceutical compounds
|
EP1978958A4
(en)
|
2006-01-24 |
2009-12-02 |
Merck & Co Inc |
INHIBITION OF TYROSINE KINASE RET
|
US8012966B2
(en)
|
2006-01-27 |
2011-09-06 |
Shanghai Hengrui Pharmaceutical Co., Ltd. |
Pyrrolo [3,2-c] pyridine-4-one 2-indolinone protein kinase inhibitors
|
AU2007227602A1
(en)
|
2006-03-16 |
2007-09-27 |
Novartis Ag |
Heterocyclic organic compounds for the treatment of in particular melanoma
|
KR101449057B1
(ko)
|
2006-03-17 |
2014-10-10 |
암비트 바이오사이언시즈 코포레이션 |
질환 치료용 이미다졸로티아졸 화합물
|
ZA200808966B
(en)
|
2006-03-27 |
2010-03-31 |
Nerviano Medical Sciences Srl |
Pyridyl- and pyrimidinyl-substituted pyrrole-, thiophene- and furane-derivatives as kinase inhibitors
|
US20090312321A1
(en)
|
2006-05-15 |
2009-12-17 |
Irm Llc |
Compositions and methods for fgf receptor kinases inhibitors
|
RU2448708C3
(ru)
|
2006-05-18 |
2017-09-28 |
Эйсай Ар Энд Ди Менеджмент Ко., Лтд. |
Противоопухолевое средство против рака щитовидной железы
|
US8063225B2
(en)
|
2006-08-14 |
2011-11-22 |
Chembridge Corporation |
Tricyclic compound derivatives useful in the treatment of neoplastic diseases, inflammatory disorders and immunomodulatory disorders
|
US20110195072A1
(en)
|
2006-09-12 |
2011-08-11 |
Anne Boulay |
Non-neuroendocrine cancer therapy
|
ES2565683T3
(es)
|
2006-09-15 |
2016-04-06 |
Xcovery, Inc. |
Compuestos inhibidores de quinasa
|
US20120225057A1
(en)
|
2006-10-11 |
2012-09-06 |
Deciphera Pharmaceuticals, Llc |
Methods and compositions for the treatment of myeloproliferative diseases and other proliferative diseases
|
EP1918291A1
(en)
|
2006-10-30 |
2008-05-07 |
Novartis AG |
3-Aminocarbonyl-substituted fused pyrazolo-derivatives as protein kinase modulators
|
LT2848610T
(lt)
|
2006-11-15 |
2017-11-10 |
Ym Biosciences Australia Pty Ltd |
Kinazės aktyvumo inhibitoriai
|
PE20121126A1
(es)
|
2006-12-21 |
2012-08-24 |
Plexxikon Inc |
Compuestos pirrolo [2,3-b] piridinas como moduladores de quinasa
|
WO2008079909A1
(en)
|
2006-12-21 |
2008-07-03 |
Plexxikon, Inc. |
Pyrrolo [2,3-b] pyridines as kinase modulators
|
JP2010514695A
(ja)
|
2006-12-21 |
2010-05-06 |
プレキシコン,インコーポレーテッド |
キナーゼ調節のための化合物および方法およびそのための適応症
|
US20080199426A1
(en)
|
2007-01-11 |
2008-08-21 |
Sukhatme Vikas P |
Methods and compositions for the treatment and diagnosis of vascular inflammatory disorders or endothelial cell disorders
|
WO2008089388A2
(en)
|
2007-01-19 |
2008-07-24 |
Bayer Healthcare Llc |
Treatment of cancers having resistance to chemotherapeutic agents
|
US20080234267A1
(en)
|
2007-03-20 |
2008-09-25 |
Karen Elizabeth Lackey |
Compounds and Methods of Treatment
|
US20110189167A1
(en)
|
2007-04-20 |
2011-08-04 |
Flynn Daniel L |
Methods and Compositions for the Treatment of Myeloproliferative Diseases and other Proliferative Diseases
|
CN101720322A
(zh)
|
2007-05-04 |
2010-06-02 |
Irm责任有限公司 |
作为c-kit和pdgfr激酶抑制剂的化合物和组合物
|
WO2008138184A1
(fr)
|
2007-05-14 |
2008-11-20 |
Shanghai Hengrui Pharmaceutical Co.Ltd. |
Dérivés de pyrrolo-azacycles, leur procédé de fabrication et leur utilisation en tant qu'inhibiteurs de protéine kinases
|
WO2009003136A1
(en)
|
2007-06-26 |
2008-12-31 |
Rigel Pharmaceuticals, Inc. |
Substituted pyrimidine-2, 4 -diamines for treating cell proliferative disorders
|
AR067478A1
(es)
|
2007-07-09 |
2009-10-14 |
Astrazeneca Ab |
Compuestos derivados de morfolina pirimidina
|
WO2009012262A1
(en)
|
2007-07-16 |
2009-01-22 |
The Regents Of The University Of California |
Protein kinase modulating compounds and methods for making and using them
|
US20100190777A1
(en)
|
2007-07-17 |
2010-07-29 |
Plexxikon Inc. |
Compounds and methods for kinase modulation, and indications therefor
|
RU2474580C2
(ru)
|
2007-07-19 |
2013-02-10 |
Шеринг Корпорейшн |
Гетероциклические амидные соединения как ингибиторы протеинкиназ
|
PL2176231T3
(pl)
|
2007-07-20 |
2017-04-28 |
Nerviano Medical Sciences S.R.L. |
Podstawione pochodne indazolu aktywne jako inhibitory kinazy
|
WO2009017838A2
(en)
|
2007-08-01 |
2009-02-05 |
Exelixis, Inc. |
Combinations of jak-2 inhibitors and other agents
|
WO2009021137A2
(en)
|
2007-08-07 |
2009-02-12 |
Purdue Research Foundation |
Kinase inhibitors and uses thereof
|
EP2025678A1
(en)
|
2007-08-17 |
2009-02-18 |
Oncalis AG |
Pyrazolo[3,4-d]pyrimidine compounds and their use as modulators of protein kinase
|
WO2009042646A1
(en)
|
2007-09-24 |
2009-04-02 |
Curis, Inc. |
Anti-proliferative agents
|
BRPI0817812A2
(pt)
|
2007-10-23 |
2015-04-14 |
Novartis Ag |
Uso de anticorpos trkb para o tratamento de distúrbios respiratórios
|
EP2215091B1
(en)
|
2007-12-04 |
2016-03-30 |
Nerviano Medical Sciences S.r.l. |
Substituted dihydropteridin-6-one derivatives, process for their preparation and their use as kinase inhibitors
|
CN101459004B
(zh)
|
2007-12-14 |
2011-02-09 |
深圳富泰宏精密工业有限公司 |
电子装置的按键面板结构及制造该按键面板结构的方法
|
EP2235062A1
(en)
|
2008-01-17 |
2010-10-06 |
Irm Llc |
Improved anti-trkb antibodies
|
US20090227556A1
(en)
|
2008-01-31 |
2009-09-10 |
Eisai R&D Management Co., Ltd. |
Receptor tyrosine kinase inhibitors comprising pyridine and pyrimidine derivatives
|
TW200942537A
(en)
|
2008-02-01 |
2009-10-16 |
Irm Llc |
Compounds and compositions as kinase inhibitors
|
WO2009103076A1
(en)
|
2008-02-15 |
2009-08-20 |
Oxigene, Inc. |
Methods and compositions for enhancing the efficacy of rtk inhibitors
|
PL2268623T3
(pl)
*
|
2008-03-17 |
2015-10-30 |
Ambit Biosciences Corp |
Pochodne chinazoliny jako modulatory kinazy RAF oraz sposoby ich zastosowania
|
AU2009226153B2
(en)
|
2008-03-19 |
2014-02-20 |
Chembridge Corporation |
Novel tyrosine kinase inhibitors
|
US8822500B2
(en)
|
2008-03-19 |
2014-09-02 |
Chembridge Corporation |
Tyrosine kinase inhibitors
|
EP2254886B1
(en)
|
2008-03-28 |
2016-05-25 |
Nerviano Medical Sciences S.r.l. |
3,4-dihydro-2h-pyrazino[1,2-a]indol-1-one derivatives active as kinase inhibitors, process for their preparation and pharmaceutical compositions comprising them
|
WO2009143018A2
(en)
|
2008-05-19 |
2009-11-26 |
Plexxikon, Inc. |
Compounds and methods for kinase modulation, and indications therefor
|
PE20091846A1
(es)
|
2008-05-19 |
2009-12-16 |
Plexxikon Inc |
DERIVADOS DE PIRROLO[2,3-d]-PIRIMIDINA COMO MODULADORES DE CINASAS
|
CN102036963B
(zh)
|
2008-05-23 |
2013-08-21 |
诺瓦提斯公司 |
作为蛋白酪氨酸激酶抑制剂的喹啉类和喹喔啉类衍生物
|
CN104530052A
(zh)
|
2008-06-10 |
2015-04-22 |
普莱希科公司 |
用于激酶调节的5h-吡咯[2,3-b]吡嗪衍生物和其适应症
|
US20110212053A1
(en)
|
2008-06-19 |
2011-09-01 |
Dapeng Qian |
Phosphatidylinositol 3 kinase inhibitors
|
EP2313091A4
(en)
|
2008-07-14 |
2012-04-04 |
Univ Kingston |
PHARMACEUTICAL COMPOSITIONS WITH RET-HEMMERN AND METHOD FOR THE TREATMENT OF CANCER
|
CN102105151B
(zh)
|
2008-07-29 |
2013-12-18 |
内尔维阿诺医学科学有限公司 |
Cdk抑制剂在治疗神经胶质瘤中的应用
|
CN102100126B
(zh)
|
2008-09-01 |
2014-04-16 |
夏普株式会社 |
有机电致发光面板、有机电致发光显示器、有机电致发光照明装置和它们的制造方法
|
US20100075916A1
(en)
|
2008-09-05 |
2010-03-25 |
Auspex Pharmaceuticals, Inc. |
Substituted quinazoline inhibitors of growth factor receptor tyrosine kinases
|
EP2161271A1
(en)
|
2008-09-08 |
2010-03-10 |
Università Degli Studi Di Milano - Bicocca |
Alpha-carboline inhibitors of NMP-ALK, RET, and Bcr-Abl
|
ES2536730T3
(es)
|
2008-09-19 |
2015-05-28 |
Nerviano Medical Sciences S.R.L. |
Derivados de 3,4-dihidro-2H-pirrolo[1,2-a]pirazin-1-ona
|
EP2350075B1
(en)
|
2008-09-22 |
2014-03-05 |
Array Biopharma, Inc. |
Substituted imidazo[1,2b]pyridazine compounds as trk kinase inhibitors
|
WO2010036629A2
(en)
|
2008-09-26 |
2010-04-01 |
National Health Research Institutes |
Fused multicyclic compounds as protein kinase inhibitors
|
PT2350071E
(pt)
|
2008-10-22 |
2014-04-11 |
Array Biopharma Inc |
Compostos de pirazol[1,5-a]pirimidina substituídos como inibidores da cinase trk
|
WO2010054058A1
(en)
|
2008-11-06 |
2010-05-14 |
Ambit Bioscience Corporation |
Imidazolothiazole compounds as modulators of protein kinase
|
US8912194B2
(en)
|
2008-11-24 |
2014-12-16 |
Nerviano Medical Sciences S.R.L. |
CDK inhibitor for the treatment of mesothelioma
|
KR101061599B1
(ko)
|
2008-12-05 |
2011-09-02 |
한국과학기술연구원 |
비정상 세포 성장 질환의 치료를 위한 단백질 키나아제 저해제인 신규 인다졸 유도체, 이의 약학적으로 허용가능한염 및 이를 유효성분으로 함유하는 약학적 조성물
|
JO3265B1
(ar)
|
2008-12-09 |
2018-09-16 |
Novartis Ag |
مثبطات بيريديلوكسى اندولات vegf-r2 واستخدامها لعلاج المرض
|
WO2010111527A1
(en)
|
2009-03-26 |
2010-09-30 |
Plexxikon, Inc. |
Pyrazolo [ 3, 4 -b] pyridines as kinase inhibitors and their medical use
|
US8492374B2
(en)
|
2009-04-29 |
2013-07-23 |
Industrial Technology Research Institute |
Azaazulene compounds
|
CA2760061C
(en)
|
2009-05-08 |
2017-02-28 |
Astellas Pharma Inc. |
Diamino heterocyclic carboxamide compound
|
JP6073677B2
(ja)
|
2009-06-12 |
2017-02-01 |
デイナ ファーバー キャンサー インスティチュート,インコーポレイテッド |
縮合複素環式化合物およびそれらの使用
|
EP3045457B1
(en)
|
2009-06-15 |
2018-05-09 |
Nerviano Medical Sciences S.r.l. |
Substituted pyrimidinylpyrrolopyridinone derivatives, process for their preparation and their use as kinase inhibitors
|
AR077468A1
(es)
|
2009-07-09 |
2011-08-31 |
Array Biopharma Inc |
Compuestos de pirazolo (1,5 -a) pirimidina sustituidos como inhibidores de trk- quinasa
|
CA2771532C
(en)
|
2009-08-17 |
2021-03-23 |
Intellikine, Inc. |
Heterocyclic compounds and uses thereof
|
KR101256018B1
(ko)
|
2009-08-20 |
2013-04-18 |
한국과학기술연구원 |
단백질 키나아제 저해활성을 갖는 1,3,6-치환된 인돌 화합물
|
CN102482283A
(zh)
*
|
2009-08-28 |
2012-05-30 |
阵列生物制药公司 |
Raf抑制剂化合物及其使用方法
|
EP2470532A1
(en)
*
|
2009-08-28 |
2012-07-04 |
Array Biopharma, Inc. |
1h-pyrazolo [ 3, 4-b]pyridine compounds for inhibiting raf kinase
|
FR2951172B1
(fr)
|
2009-10-13 |
2014-09-26 |
Pf Medicament |
Derives pyrazolopyridines en tant qu'agent anticancereux
|
KR101147550B1
(ko)
|
2009-10-22 |
2012-05-17 |
한국과학기술연구원 |
단백질 키나아제 저해활성을 가지는 2,7-치환된 티에노[3,2-d]피리미딘 화합물
|
KR101116756B1
(ko)
|
2009-10-27 |
2012-03-13 |
한국과학기술연구원 |
단백질 키나아제 저해활성을 갖는 신규의 1,6-치환된 인돌 화합물
|
JP5993742B2
(ja)
|
2009-10-29 |
2016-09-14 |
ジェノスコ |
キナーゼ阻害剤
|
MX2012005332A
(es)
|
2009-11-13 |
2012-10-15 |
Oscotec Inc |
Inhibidores de cinasa.
|
KR101094446B1
(ko)
|
2009-11-19 |
2011-12-15 |
한국과학기술연구원 |
단백질 키나아제 저해활성을 가지는 2,4,7-치환된 티에노[3,2-d]피리미딘 화합물
|
EP2937345B1
(en)
|
2009-12-29 |
2018-03-21 |
Dana-Farber Cancer Institute, Inc. |
Type ii raf kinase inhibitors
|
RU2524210C2
(ru)
|
2010-01-29 |
2014-07-27 |
Ханми Сайенс Ко., Лтд. |
ПРОИЗВОДНЫЕ ТИЕНО[3,2-d]ПИРИМИДИНА, ОБЛАДАЮЩИЕ ИНГИБИРУЮЩЕЙ АКТИВНОСТЬЮ В ОТНОШЕНИИ ПРОТЕИНКИНАЗЫ
|
KR101483215B1
(ko)
|
2010-01-29 |
2015-01-16 |
한미약품 주식회사 |
단백질 키나아제 저해활성을 갖는 비시클릭 헤테로아릴 유도체
|
US8772279B2
(en)
|
2010-01-29 |
2014-07-08 |
Nerviano Medical Sciences S.R.L. |
6,7-dihydroimidazo[1,5-a]pyrazin-8(5H)-one derivatives as protein kinase modulators
|
EP2536414B1
(en)
|
2010-02-18 |
2016-07-13 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Method for preventing cancer metastasis
|
TWI510487B
(zh)
|
2010-04-21 |
2015-12-01 |
Plexxikon Inc |
用於激酶調節的化合物和方法及其適應症
|
CN102985422A
(zh)
*
|
2010-05-12 |
2013-03-20 |
Abbvie公司 |
激酶的吡咯并吡啶和吡咯并嘧啶抑制剂
|
BR122019024201B1
(pt)
|
2010-05-20 |
2021-08-03 |
Array Biopharma Inc |
Composto macrocíclico como inibidores de trk quinase, seu uso, e composição farmacêutica
|
WO2012034095A1
(en)
|
2010-09-09 |
2012-03-15 |
Irm Llc |
Compounds and compositions as trk inhibitors
|
US8637516B2
(en)
|
2010-09-09 |
2014-01-28 |
Irm Llc |
Compounds and compositions as TRK inhibitors
|
WO2012047017A2
(ko)
|
2010-10-05 |
2012-04-12 |
크리스탈지노믹스(주) |
2,3-디히드로-이소인돌-1-온 유도체 및 이를 포함하는 조성물
|
JP2014005206A
(ja)
|
2010-10-22 |
2014-01-16 |
Astellas Pharma Inc |
アリールアミノヘテロ環カルボキサミド化合物
|
JP5925808B2
(ja)
|
2011-01-26 |
2016-05-25 |
ネルビアーノ・メデイカル・サイエンシーズ・エツセ・エルレ・エルレ |
三環式誘導体、これらの調製方法およびこれらのキナーゼ阻害剤としての使用
|
BR112013018515B1
(pt)
|
2011-01-26 |
2021-06-29 |
Nerviano Medical Sciences S.R.I |
Derivados de pirrol tricíclico, processo para sua preparação e seu uso como inibidores da quinase
|
CN102093421B
(zh)
|
2011-01-28 |
2014-07-02 |
北京康辰药业有限公司 |
一种含磷取代基的喹啉类化合物及其制备方法、以及含有该化合物的药物组合物及其应用
|
AU2012214762B2
(en)
|
2011-02-07 |
2015-08-13 |
Plexxikon Inc. |
Compounds and methods for kinase modulation, and indications therefor
|
ES2580961T3
(es)
|
2011-02-24 |
2016-08-30 |
Nerviano Medical Sciences S.R.L. |
Derivados Tiazolilfenil-bencenosulfonamido como Inhibidores de Cinasa
|
KR20140014184A
(ko)
|
2011-02-25 |
2014-02-05 |
아이알엠 엘엘씨 |
Trk 억제제로서의 화합물 및 조성물
|
WO2012135631A1
(en)
|
2011-03-30 |
2012-10-04 |
Arrien Pharmaeuticals Llc |
Substituted 5-(pyrazin-2-yl)-1h-pyrazolo [3, 4-b] pyridine and pyrazolo [3, 4-b] pyridine derivatives as protein kinase inhibitors
|
JP6118794B2
(ja)
|
2011-04-01 |
2017-04-19 |
ザ ユニバーシティ オブ ユタ リサーチ ファウンデイション |
Axlキナーゼの阻害剤としての置換n−フェニルピリミジン−2−アミン類似体
|
JP5976778B2
(ja)
|
2011-04-11 |
2016-08-24 |
ネルビアーノ・メデイカル・サイエンシーズ・エツセ・エルレ・エルレ |
キナーゼ阻害剤としてのピラゾリル−ピリミジン誘導体
|
BR112013026137B1
(pt)
|
2011-04-19 |
2020-12-01 |
Nerviano Medical Sciences S.R.L |
pirimidinil-pirróis substituídos ativos como inibidores da quinase
|
AR086042A1
(es)
|
2011-04-28 |
2013-11-13 |
Galapagos Nv |
Compuesto util para el tratamiento de enfermedades degenerativas e inflamatorias y composicion farmaceutica
|
MX342509B
(es)
|
2011-05-12 |
2016-10-03 |
Nerviano Medical Sciences Srl |
Compuestos de indazol sustituidos como inhibidores de las cinasas de proteina.
|
PL2712358T3
(pl)
|
2011-05-13 |
2017-05-31 |
Array Biopharma, Inc. |
Związki mocznika pirolidynowego, tiomocznika pirolidynowego oraz guanidyny pirolidynowej jako inhibitory kinazy trka
|
RU2477723C2
(ru)
|
2011-06-16 |
2013-03-20 |
Общество С Ограниченной Ответственностью "Фьюжн Фарма" |
Ингибиторы протеинкиназ (варианты), их применение для лечения онкологических заболеваний и фармацевтическая композиция на их основе
|
CN102827073A
(zh)
*
|
2011-06-17 |
2012-12-19 |
安吉奥斯医药品有限公司 |
治疗活性组合物和它们的使用方法
|
WO2013016720A2
(en)
|
2011-07-28 |
2013-01-31 |
Gerinda Therapeutics, Inc. |
Novel substituted biarylheterocycle derivatives as protein kinase inhibitors for the treatment of cancer and other diseases
|
JP6016915B2
(ja)
|
2011-07-28 |
2016-10-26 |
ネルビアーノ・メデイカル・サイエンシーズ・エツセ・エルレ・エルレ |
キナーゼ阻害剤として活性なアルキニル置換ピリミジニルピロール
|
IN2014DN01605A
(pt)
|
2011-08-04 |
2015-05-15 |
Nat Cancer Ct |
|
EP3564261A1
(en)
|
2011-08-23 |
2019-11-06 |
Foundation Medicine, Inc. |
Kif5b-ret fusion molecules and uses thereof
|
CA2846496C
(en)
|
2011-09-02 |
2020-07-14 |
The Regents Of The University Of California |
Substituted pyrazolo[3,4-d]pyrimidines and uses thereof
|
WO2013036232A2
(en)
|
2011-09-08 |
2013-03-14 |
Deciphera Pharmaceuticals, Llc |
Methods and compositions for the treatment of myeloproliferative diseases and other proliferative diseases
|
CN102408411B
(zh)
|
2011-09-19 |
2014-10-22 |
北京康辰药业股份有限公司 |
一种含喹啉基的羟肟酸类化合物及其制备方法、以及含有该化合物的药物组合物及其应用
|
WO2013042137A1
(en)
|
2011-09-19 |
2013-03-28 |
Aurigene Discovery Technologies Limited |
Bicyclic heterocycles as irak4 inhibitors
|
EP2788350B1
(en)
|
2011-10-07 |
2017-12-06 |
Nerviano Medical Sciences S.r.l. |
4-ALKYL SUBSTITUTED 3,4-DIHYDROPYRROLO[1,2-a]PYRAZIN-1(2H)-ONE DERIVATIVES AS KINASES INHIBITORS
|
ES2639064T3
(es)
|
2011-10-07 |
2017-10-25 |
Nerviano Medical Sciences S.R.L. |
Derivados de 3,4-dihidropirrolo[1,2-a]pirazin-1(2h)-ona sustituidos como inhibidores de cinasa
|
WO2013074518A1
(en)
|
2011-11-14 |
2013-05-23 |
Tesaro, Inc. |
Modulating certain tyrosine kinases
|
KR20140100938A
(ko)
|
2011-11-30 |
2014-08-18 |
도쿠리츠교세이호진 고쿠리츠간켄큐센터 |
유도 악성 줄기세포
|
US8377946B1
(en)
|
2011-12-30 |
2013-02-19 |
Pharmacyclics, Inc. |
Pyrazolo[3,4-d]pyrimidine and pyrrolo[2,3-d]pyrimidine compounds as kinase inhibitors
|
RS59420B1
(sr)
|
2011-12-30 |
2019-11-29 |
Hanmi Pharmaceutical Co Ltd |
Derivati tieno[3,2-d]pirimidina sa inhibitornom aktivnošću za proteinske kinaze
|
JP2015109806A
(ja)
|
2012-03-22 |
2015-06-18 |
アステラス製薬株式会社 |
新規ret融合体の検出法
|
ES2605388T3
(es)
|
2012-04-26 |
2017-03-14 |
Ono Pharmaceutical Co., Ltd. |
Compuesto inhibidor de Trk
|
CA2871540A1
(en)
|
2012-05-10 |
2013-11-14 |
Synta Pharmaceuticals Corp. |
Treating cancer with hsp90 inhibitory compounds
|
CN104395308B
(zh)
|
2012-05-23 |
2016-08-24 |
内尔维阿诺医学科学有限公司 |
N-[5-(3,5-二氟-苄基)-1h-吲唑-3-基]-4-(4-甲基-哌嗪-1-基)-2-(四氢-吡喃-4-基氨基)-苯甲酰胺的制备方法
|
TWI585088B
(zh)
|
2012-06-04 |
2017-06-01 |
第一三共股份有限公司 |
作爲激酶抑制劑之咪唑并[1,2-b]嗒衍生物
|
RU2019102203A
(ru)
|
2012-07-11 |
2019-03-05 |
Блюпринт Медсинс Корпорейшн |
Ингибиторы рецептора фактора роста фибробластов
|
CN104619841A
(zh)
|
2012-07-26 |
2015-05-13 |
日本国立癌症研究中心 |
Cep55基因与ret基因的融合基因
|
ES2726833T3
(es)
|
2012-08-02 |
2019-10-09 |
Nerviano Medical Sciences Srl |
Pirroles sustituidos activos como inhibidores de cinasas
|
WO2014039971A1
(en)
|
2012-09-07 |
2014-03-13 |
Exelixis, Inc. |
Inhibitors of met, vegfr and ret for use in the treatment of lung adenocarcinoma
|
AU2013321235B2
(en)
|
2012-09-25 |
2017-07-20 |
Chugai Seiyaku Kabushiki Kaisha |
RET inhibitor
|
US9604980B2
(en)
|
2012-11-07 |
2017-03-28 |
Nerviano Medical Sciences S.R.L. |
Substituted pyrimidinyl and pyridinyl-pyrrolopyridinones, process for their preparation and their use as kinase inhibitors
|
AU2013342015B2
(en)
|
2012-11-12 |
2016-11-24 |
Ignyta, Inc. |
Bendamustine derivatives and methods of using same
|
US9546156B2
(en)
|
2012-11-13 |
2017-01-17 |
Array Biopharma Inc. |
N-bicyclic aryl,N'-pyrazolyl urea, thiourea, guanidine cyanoguanidine compounds as TrkA kinase inhibitors
|
US9828360B2
(en)
|
2012-11-13 |
2017-11-28 |
Array Biopharma Inc. |
Pyrrolidinyl urea, thiourea, guanidine and cyanoguanidine compounds as TrkA kinase inhibitors
|
US9969694B2
(en)
|
2012-11-13 |
2018-05-15 |
Array Biopharma Inc. |
N-(arylalkyl)-N′-pyrazolyl-urea, thiourea, guanidine and cyanoguanidine compounds as TrkA kinase inhibitors
|
US9790210B2
(en)
|
2012-11-13 |
2017-10-17 |
Array Biopharma Inc. |
N-(monocyclic aryl),N'-pyrazolyl-urea, thiourea, guanidine and cyanoguanidine compounds as TrkA kinase inhibitors
|
WO2014078372A1
(en)
|
2012-11-13 |
2014-05-22 |
Array Biopharma Inc. |
Pyrrolidinyl urea, thiourea, guanidine and cyanoguanidine compounds as trka kinase inhibitors
|
US9981959B2
(en)
|
2012-11-13 |
2018-05-29 |
Array Biopharma Inc. |
Thiazolyl and oxazolyl urea, thiourea, guanidine and cyanoguanidine compounds as TrkA kinase inhibitors
|
PL2922844T3
(pl)
|
2012-11-13 |
2018-06-29 |
Array Biopharma, Inc. |
N-pirolidynyl, n’-pirazolilowe związki mocznika, tiomocznika, guanidyny i cyjanoguanidyny jako inhibitory kinazy trka
|
HUE031557T2
(en)
|
2012-11-13 |
2017-07-28 |
Array Biopharma Inc |
Bicyclic urea, thiourea, guanidine, and cyanoguadinine compounds used to treat pain
|
US9822118B2
(en)
|
2012-11-13 |
2017-11-21 |
Array Biopharma Inc. |
Bicyclic heteroaryl urea, thiourea, guanidine and cyanoguanidine compounds as TrkA kinase inhibitors
|
US9809578B2
(en)
|
2012-11-13 |
2017-11-07 |
Array Biopharma Inc. |
Pyrazolyl urea, thiourea, guanidine and cyanoguanidine compounds as trkA kinase inhibitors
|
CA2877847A1
(en)
|
2012-11-29 |
2014-06-05 |
Yeda Research And Development Co. Ltd. |
Methods of preventing tumor metastasis, treating and prognosing cancer and identifying agents which are putative metastasis inhibitors
|
CN103848785B
(zh)
|
2012-12-04 |
2016-07-13 |
上海医药集团股份有限公司 |
一类氘代3-氰基喹啉类化合物、其药用组合物、制备方法及其用途
|
FR3000494B1
(fr)
|
2012-12-28 |
2015-08-21 |
Oribase Pharma |
Nouveaux derives d'azaindoles en tant qu'inhibiteurs de proteines kinases
|
FR3000493A1
(fr)
|
2012-12-28 |
2014-07-04 |
Oribase Pharma |
Nouveaux inhibiteurs de proteines kinases
|
ES2696700T3
(es)
|
2012-12-28 |
2019-01-17 |
Crystalgenomics Inc |
Derivado de 2,3-dihidro-isoindol-1-on como supresor de quinasa BTK y composición farmacéutica que incluye el mismo
|
FR3000492B1
(fr)
|
2012-12-28 |
2015-09-11 |
Oribase Pharma |
Nouveaux derives azaindole en tant qu'inhibiteurs multikinases
|
HUE042591T2
(hu)
|
2013-02-19 |
2019-07-29 |
Ono Pharmaceutical Co |
TRK-gátló vegyület
|
WO2014160524A1
(en)
|
2013-03-14 |
2014-10-02 |
The Trustees Of The University Of Pennsylvania |
Cardio- metabolic and cascular effects of glp-1 metabolites
|
MX2015012286A
(es)
|
2013-03-15 |
2016-05-31 |
Glaxosmithkline Ip Dev Ltd |
Derivados de piridina como inhibidores de cinasa reordenada durante transfección.
|
US8937071B2
(en)
|
2013-03-15 |
2015-01-20 |
Glaxosmithkline Intellectual Property Development Limited |
Compounds as rearranged during transfection (RET) inhibitors
|
WO2014160521A1
(en)
|
2013-03-15 |
2014-10-02 |
Blueprint Medicines Corporation |
Piperazine derivatives and their use as kit modulators
|
ES2646019T3
(es)
*
|
2013-05-14 |
2017-12-11 |
Nerviano Medical Sciences S.R.L. |
Derivados de 6-amino-7-deaza-purina, proceso para su preparación y su uso como inhibidores de cinasa
|
BR112015028845A2
(pt)
|
2013-05-30 |
2017-07-25 |
Plexxikon Inc |
compostos para a modulação da quinase e indicações da mesma
|
EP3027654B1
(en)
|
2013-07-30 |
2019-09-25 |
Blueprint Medicines Corporation |
Pik3c2g fusions
|
WO2015017533A1
(en)
|
2013-07-30 |
2015-02-05 |
Blueprint Medicines Corporation |
Ntrk2 fusions
|
CN105658814A
(zh)
|
2013-08-20 |
2016-06-08 |
日本国立癌症研究中心 |
在肺癌中检测出的新型融合基因
|
KR20160055170A
(ko)
|
2013-08-30 |
2016-05-17 |
암비트 바이오사이언시즈 코포레이션 |
바이아릴 아세트아미드 화합물 및 이의 사용 방법
|
LT3057969T
(lt)
|
2013-10-17 |
2018-07-10 |
Blueprint Medicines Corporation |
Kompozicijos, naudojamos gydyti sutrikimams, susijusiems su kit
|
WO2015058129A1
(en)
|
2013-10-17 |
2015-04-23 |
Blueprint Medicines Corporation |
Compositions useful for treating disorders related to kit
|
PL3395814T3
(pl)
|
2013-10-25 |
2022-08-22 |
Blueprint Medicines Corporation |
Inhibitory receptora czynników wzrostu fibroblastów
|
GB201321146D0
(en)
|
2013-11-29 |
2014-01-15 |
Cancer Rec Tech Ltd |
Quinazoline compounds
|
JP6992960B2
(ja)
|
2013-12-02 |
2022-02-03 |
ベルゲンビオ アーエスアー |
キナーゼ阻害剤の用途
|
SG11201605207PA
(en)
*
|
2013-12-26 |
2016-07-28 |
Ignyta Inc |
Pyrazolo[1,5-a]pyridine derivatives and methods of their use
|
WO2015108992A1
(en)
|
2014-01-15 |
2015-07-23 |
Blueprint Medicines Corporation |
Heterobicyclic compounds and their use as fgfr4 receptor inhibitors
|
MY193524A
(en)
|
2014-01-24 |
2022-10-18 |
Turning Point Therapeutics Inc |
Diaryl macrocycles as modulators of protein kinases
|
BR112016018450A2
(pt)
|
2014-02-14 |
2018-09-18 |
Exelixis Inc |
formas sólidas cristalinas de n-{4-[(6,7-dimetoxiquinolin-4-il)oxi]fenil}-n'-(4-fluorofenil)ciclopropano-1,1-dicarboxamida, processos de preparo e métodos de uso
|
TWI672141B
(zh)
|
2014-02-20 |
2019-09-21 |
美商醫科泰生技 |
投予ros1突變癌細胞之分子
|
US20170044621A1
(en)
|
2014-04-18 |
2017-02-16 |
Blueprint Medicines Corporation |
Met fusions
|
EP3132056B1
(en)
|
2014-04-18 |
2021-11-24 |
Blueprint Medicines Corporation |
Pik3ca fusions
|
CR20160583A
(es)
|
2014-05-15 |
2017-02-23 |
Array Biopharma Inc |
1-((3s,4r)-4-(3-fluorofenil)-1-(2-metoxietil)pirrolidin-3-il)-3-(4-metil-3-(2-metilpirimidin-5-il)-1-fenil-1h-pirazol-5-il)urea como inhibidor de trka cinasa
|
WO2015191667A1
(en)
|
2014-06-10 |
2015-12-17 |
Blueprint Medicines Corporation |
Pkn1 fusions
|
WO2015191666A2
(en)
|
2014-06-10 |
2015-12-17 |
Blueprint Medicines Corporation |
Raf1 fusions
|
US10370723B2
(en)
|
2014-07-17 |
2019-08-06 |
Blueprint Medicines Corporation |
TERT fusions
|
EP3169809B1
(en)
|
2014-07-17 |
2020-04-29 |
Blueprint Medicines Corporation |
Prkc fusions
|
HUE046008T2
(hu)
|
2014-07-17 |
2020-02-28 |
Sunshine Lake Pharma Co Ltd |
I-(5-terc-butil)-izoxazol-3-il)-3-(4-((feniI)-etinil)-fenil)-kabamid származékok, valamint az ezekkel rokon vegyületek FLT-3 inhibitorokként rák kezelésére
|
WO2016011141A1
(en)
|
2014-07-17 |
2016-01-21 |
Blueprint Medicines Corporation |
Fgr fusions
|
US9688680B2
(en)
|
2014-08-04 |
2017-06-27 |
Blueprint Medicines Corporation |
Compositions useful for treating disorders related to kit
|
PL3184519T3
(pl)
|
2014-08-18 |
2019-09-30 |
Ono Pharmaceutical Co., Ltd. |
Sole addycyjne z kwasem związku hamującego trk
|
JP2017527574A
(ja)
|
2014-09-08 |
2017-09-21 |
グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドGlaxosmithkline Intellectual Property Development Limited |
2−(4−(4−エトキシ−6−オキソ−1,6−ジヒドロピリジン−3−イル)−2−フルオロフェニル)−n−(5−(1,1,1−トリフルオロ−2−メチルプロパン−2−イル)イソオキサゾール−3−イル)アセトアミドの結晶形
|
SG11201701695UA
(en)
|
2014-09-10 |
2017-04-27 |
Glaxosmithkline Ip Dev Ltd |
Novel compounds as rearranged during transfection (ret) inhibitors
|
DK3191450T3
(da)
|
2014-09-10 |
2019-05-20 |
Glaxosmithkline Ip Dev Ltd |
Pyridonderivater som kinasehæmmere omarrangeret under transfektion (ret)
|
TWI538914B
(zh)
|
2014-10-03 |
2016-06-21 |
國立交通大學 |
蛋白質激酶之選擇性抑制劑、其醫藥組成物及其用途
|
KR102562866B1
(ko)
|
2014-11-14 |
2023-08-04 |
네르비아노 메디칼 사이언시스 에스.알.엘. |
단백질 키나아제 억제제로서의 6-아미노-7-바이사이클로-7-데아자-퓨린 유도체
|
NZ731909A
(en)
|
2014-11-16 |
2023-11-24 |
Array Biopharma Inc |
Crystalline form of (s)-n-(5-((r)-2-(2,5-difluorophenyl)-pyrrolidin-1-yl)-pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide hydrogen sulfate
|
US20170356052A1
(en)
|
2014-11-18 |
2017-12-14 |
Blueprint Medicines Corporation |
Prkacb fusions
|
US10336707B2
(en)
|
2014-12-16 |
2019-07-02 |
Eudendron S.R.L. |
Heterocyclic derivatives modulating activity of certain protein kinases
|
WO2016127074A1
(en)
|
2015-02-06 |
2016-08-11 |
Blueprint Medicines Corporation |
2-(pyridin-3-yl)-pyrimidine derivatives as ret inhibitors
|
KR101675984B1
(ko)
|
2015-02-23 |
2016-11-14 |
한양대학교 에리카산학협력단 |
티에노디아제핀 유도체 또는 이의 약학적으로 허용가능한 염, 및 이를 유효성분으로 포함하는 약학적 조성물
|
EP3265079A4
(en)
|
2015-03-03 |
2019-01-02 |
Caris MPI, Inc. |
Molecular profiling for cancer
|
WO2016168992A1
(en)
|
2015-04-21 |
2016-10-27 |
Ruijin Hospital Affiliated To Shanghai Jiao Tong University School Of Medicine |
Preparation and use of novel protein kinase inhibitors
|
GB201512365D0
(en)
|
2015-07-15 |
2015-08-19 |
King S College London |
Novel therapy
|
AU2016291676B2
(en)
*
|
2015-07-16 |
2020-04-30 |
Array Biopharma, Inc. |
Substituted pyrazolo[1,5-a]pyridine compounds as RET kinase inhibitors
|
EP3120851A1
(en)
|
2015-07-21 |
2017-01-25 |
Pangaea Biotech S.L. |
4-amino-6-(2,6-dichlorophenyl)-8-methyl-2-(phenylamino)-pyrido[2,3-d]pyrimidin-7(8h)-one for treatment of solid cancers
|
KR101766194B1
(ko)
|
2015-08-07 |
2017-08-10 |
한국과학기술연구원 |
RET 키나아제 저해제인 신규 3-(이속사졸-3-일)-피라졸로[3,4-d]피리미딘-4-아민 화합물
|
WO2017027883A1
(en)
|
2015-08-13 |
2017-02-16 |
San Diego State University Research Foundation |
Atropisomerism for increased kinase inhibitor selectivity
|
MA41559A
(fr)
|
2015-09-08 |
2017-12-26 |
Taiho Pharmaceutical Co Ltd |
Composé de pyrimidine condensé ou un sel de celui-ci
|
WO2017049462A1
(zh)
|
2015-09-22 |
2017-03-30 |
合肥中科普瑞昇生物医药科技有限公司 |
一类新型的flt3激酶抑制剂及其用途
|
CN105255927B
(zh)
|
2015-09-30 |
2018-07-27 |
温州医科大学附属第一医院 |
一种kiaa1217-ret融合基因
|
MX2018005528A
(es)
|
2015-11-02 |
2018-11-09 |
Blueprint Medicines Corp |
Inhibidores de ret.
|
US20190002988A1
(en)
|
2015-12-08 |
2019-01-03 |
Boehringer Ingelheim International Gmbh |
Method of using a ret fusion gene as a biomarker to select non small cell lung cancer (nsclc) and thyroid cancer patients for a cancer treatment
|
JP6871869B2
(ja)
|
2016-01-15 |
2021-05-19 |
公益財団法人がん研究会 |
新規融合体及びその検出法
|
TWI620748B
(zh)
|
2016-02-05 |
2018-04-11 |
National Health Research Institutes |
氨基噻唑化合物及其用途
|
IL261107B2
(en)
|
2016-02-23 |
2023-11-01 |
Taiho Pharmaceutical Co Ltd |
A novel compressed pyrimidine compound or a salt thereof
|
WO2017145050A1
(en)
|
2016-02-23 |
2017-08-31 |
Glaxosmithkline Intellectual Property Development Limited |
Pyridylpyridone derivative useful as a ret kinase inhibitor in the treatment of ibs and cancer
|
AR107912A1
(es)
|
2016-03-17 |
2018-06-28 |
Blueprint Medicines Corp |
Inhibidores de ret
|
US10045991B2
(en)
|
2016-04-04 |
2018-08-14 |
Loxo Oncology, Inc. |
Methods of treating pediatric cancers
|
JP6943876B2
(ja)
|
2016-04-15 |
2021-10-06 |
キャンサー・リサーチ・テクノロジー・リミテッドCancer Research Technology Limited |
Retキナーゼ阻害剤としての複素環化合物
|
RS63609B1
(sr)
|
2016-04-15 |
2022-10-31 |
Cancer Research Tech Ltd |
Heterociklična jedinjenja kao inhibitori ret kinaze
|
JOP20190077A1
(ar)
|
2016-10-10 |
2019-04-09 |
Array Biopharma Inc |
مركبات بيرازولو [1، 5-a]بيريدين بها استبدال كمثبطات كيناز ret
|
TWI704148B
(zh)
|
2016-10-10 |
2020-09-11 |
美商亞雷生物製藥股份有限公司 |
作為ret激酶抑制劑之經取代吡唑并[1,5-a]吡啶化合物
|