RU2017126724A - Пиколинамиды в качестве фунгицидов - Google Patents

Пиколинамиды в качестве фунгицидов Download PDF

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RU2017126724A
RU2017126724A RU2017126724A RU2017126724A RU2017126724A RU 2017126724 A RU2017126724 A RU 2017126724A RU 2017126724 A RU2017126724 A RU 2017126724A RU 2017126724 A RU2017126724 A RU 2017126724A RU 2017126724 A RU2017126724 A RU 2017126724A
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compound
hydrogen
optionally substituted
alkyl
aryl
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Захари БАКЕН
Кайл А. ДЕКОРВЕР
Дэвид М. ДЖОУНС
Джессика ХЕРРИК
Джереми ВИЛМОТ
Джаред РИГОЛИ
Брайан ЛОЙ
Юй ЛУ
Кевин Дж. МЕЙЕР
Чэнлинь Яо
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ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи
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    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
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    • A01N37/00Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/44Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
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    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/02Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
    • A01N43/04Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom
    • A01N43/14Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom six-membered rings
    • A01N43/18Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom six-membered rings with sulfur as the ring hetero atom
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    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/34Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
    • A01N43/40Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/72Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
    • A01N43/74Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,3
    • A01N43/781,3-Thiazoles; Hydrogenated 1,3-thiazoles
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/08Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
    • A01N47/10Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof
    • A01N47/12Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof containing a —O—CO—N< group, or a thio analogue thereof, neither directly attached to a ring nor the nitrogen atom being a member of a heterocyclic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Claims (44)

1. Соединение формулы I
Figure 00000001
где X представляет собой водород или C(O)R5;
Y представляет собой водород, C(O)R5, или Q;
Q представляет собой
Figure 00000002
;
R1 и R11 независимо выбраны из водорода или алкила, необязательно замещенных 0, 1 или несколькими R8; альтернативно, R1 и R11 можно брать вместе с формированием 3-6-членного насыщенного или частично насыщенного углеродного цикла или гетероцикла, необязательно замещенного 0, 1 или несколькими R8;
R2 и R12 независимо выбраны из водорода или метила;
R3 выбран из арила или гетероарила, каждый из которых необязательно замещен 0, 1 или несколькими R8;
R4 выбран из алкила, арила или ацила, каждый из которых необязательно замещен 0, 1 или несколькими R8;
R5 выбран из алкокси или бензилокси, каждый из которых необязательно замещен 0, 1 или несколькими R8;
R6 выбран из водорода, алкокси или галогена, каждый из которых необязательно замещен 0, 1 или несколькими R8;
R7 выбран из водорода, -C(O)R9 или -CH2OC(O)R9;
R8 выбран из водорода, алкила, арила, ацила, галогена, алкенила, алкокси или гетероциклила, каждый из которых необязательно замещен 0, 1 или несколькими R10;
R9 выбран из алкила, алкокси или арила, каждый из которых необязательно замещен 0, 1 или несколькими R8;
R10 выбран из водорода, алкила, арила, ацила, галогена, алкенила, алкокси или гетероциклила.
2. Соединение по п. 1, где X и Y представляют собой водород.
3. Соединение по п. 2, где R1 и R11 независимо выбраны из водорода или алкила.
4. Соединение по п. 2, где R2 и R12 независимо выбраны из водорода или метила.
5. Соединение по п. 2, где R3 представляет собой арил, необязательно замещенный 0, 1 или несколькими R8.
6. Соединение по п. 2, где R4 выбран из алкила или арила, каждый из которых необязательно замещен 0, 1 или несколькими R8.
7. Соединение по п. 2, где R1 и R11 независимо выбраны из водорода или алкила, R2 и R12 независимо выбраны из водорода или метила, R3 представляет собой арил, необязательно замещенный 0, 1 или несколькими R8, и R4 выбран из алкила или арила, каждый из которых необязательно замещен 0, 1 или несколькими R8.
8. Соединение по п. 1, где X представляет собой C(O)R5, и Y представляет собой водород.
9. Соединение по п. 8, где R1 и R11 независимо выбраны из водорода или алкила.
10. Соединение по п. 8, где R2 и R12 независимо выбраны из водорода или метила.
11. Соединение по п. 8, где R3 представляет собой арил, необязательно замещенный 0, 1 или несколькими R8;
12. Соединение по п. 8, где R4 выбран из алкила или арила, каждый из которых необязательно замещен 0, 1 или несколькими R8.
13. Соединение по п. 8, где R1 и R11 независимо выбраны из водорода или алкила, R2 и R12 независимо выбраны из водорода или метила, R3 представляет собой арил, необязательно замещенный 0, 1 или несколькими R8, и R4 выбран из алкила или арила, каждый из которых необязательно замещен 0, 1 или несколькими R8.
14. Соединение по п. 1, где X представляет собой водород и Y представляет собой Q.
15. Соединение по п. 14, где R7 представляет собой водород.
16. Соединение по п. 15, где R6 представляет собой алкокси.
17. Соединение по п. 16, где R1 и R11 независимо выбраны из водорода или алкила.
18. Соединение по п. 16, где R2 и R12 независимо выбраны из водорода или метила.
19. Соединение по п. 16, где R3 представляет собой арил, необязательно замещенный 0, 1 или несколькими R8;
20. Соединение по п. 16, где R4 выбран из алкила или арила, каждый из которых необязательно замещен 0, 1 или несколькими R8.
21. Соединение по п. 16, где R1 и R11 независимо выбраны из водорода или алкила, R2 и R12 независимо выбраны из водорода или метила, R3 представляет собой арил, необязательно замещенный 0, 1 или несколькими R8; и R4 выбран из алкила или арила, каждый из которых необязательно замещен 0, 1 или несколькими R8.
22. Соединение по п. 15, где R7 выбран из -C(O)R9, или -CH2OC(O)R9.
23. Соединение по п. 22, где R9 представляет собой алкил, необязательно замещенный 0, 1 или несколькими R8.
24. Соединение по п. 23, где R1 и R11 независимо выбраны из водорода или алкила.
25. Соединение по п. 23, где R2 и R12 независимо выбраны из водорода или метила.
26. Соединение по п. 23, где R3 представляет собой арил, необязательно замещенный 0, 1 или несколькими R8;
27. Соединение по п. 23, где R4 выбран из алкила или арила, каждый из которых необязательно замещен 0, 1 или несколькими R8.
28. Соединение по п. 23, где R1 и R11 независимо выбраны из водорода или алкила, R2 и R12 независимо выбраны из водорода или метила, R3 представляет собой арил, необязательно замещенный 0, 1 или несколькими R8; и R4 выбран из алкила или арила, каждый из которых необязательно замещен 0, 1 или несколькими R8.
29. Соединение по п. 28, где R9 выбран из -CH3, -CH2OCH2CH3, -CH2CH2OCH3, -CH(CH3)2, -CH2CH2CH2CH3, -циклопропила.
RU2017126724A 2014-12-30 2015-12-21 Пиколинамиды в качестве фунгицидов RU2686987C2 (ru)

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US201462098089P 2014-12-30 2014-12-30
US201462098097P 2014-12-30 2014-12-30
US62/098,089 2014-12-30
US62/098,097 2014-12-30
US201562255163P 2015-11-13 2015-11-13
US201562255168P 2015-11-13 2015-11-13
US62/255,163 2015-11-13
US62/255,168 2015-11-13
PCT/US2015/067206 WO2016109304A1 (en) 2014-12-30 2015-12-21 Picolinamides as fungicides

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Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107205385A (zh) 2014-12-30 2017-09-26 美国陶氏益农公司 吡啶酰胺作为杀真菌剂的用途
BR112017013653A2 (pt) 2014-12-30 2018-03-13 Dow Agrosciences Llc uso de compostos de picolinamida com atividade fungicida
RU2702088C2 (ru) 2014-12-30 2019-10-03 ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи Применение соединений пиколинамида в качестве фунгицидов
CN107205397A (zh) 2014-12-30 2017-09-26 美国陶氏益农公司 具有杀真菌活性的吡啶酰胺化合物的用途
KR20170100547A (ko) 2014-12-30 2017-09-04 다우 아그로사이언시즈 엘엘씨 살진균 활성을 갖는 피콜린아미드
US10173982B2 (en) 2016-08-30 2019-01-08 Dow Agrosciences Llc Picolinamides as fungicides
WO2018045012A1 (en) * 2016-08-30 2018-03-08 Dow Agrosciences Llc Pyrido-1,3-oxazine-2,4-dione compounds with fungicidal activity
WO2018045006A1 (en) 2016-08-30 2018-03-08 Dow Agrosciences Llc Picolinamide n-oxide compounds with fungicidal activity
US10172358B2 (en) 2016-08-30 2019-01-08 Dow Agrosciences Llc Thiopicolinamide compounds with fungicidal activity
BR102018000183B1 (pt) 2017-01-05 2023-04-25 Dow Agrosciences Llc Picolinamidas, composição para controle de um patógeno fúngico, e método para controle e prevenção de um ataque por fungos em uma planta
CN110996665B (zh) 2017-05-02 2021-10-26 陶氏益农公司 无环吡啶酰胺化合物作为针对草坪草上的真菌病害的杀真菌剂的用途
TW201842851A (zh) 2017-05-02 2018-12-16 美商陶氏農業科學公司 用於穀類中的真菌防治之協同性混合物
TW201902357A (zh) * 2017-05-02 2019-01-16 美商陶氏農業科學公司 用作種子處理之無環吡啶醯胺
TWI774761B (zh) 2017-05-02 2022-08-21 美商科迪華農業科技有限責任公司 用於穀物中的真菌防治之協同性混合物
WO2019121149A1 (en) * 2017-12-19 2019-06-27 Syngenta Participations Ag Microbiocidal picolinamide derivatives
BR102019004480B1 (pt) 2018-03-08 2023-03-28 Dow Agrosciences Llc Picolinamidas como fungicidas
BR112021006669A2 (pt) 2018-10-15 2021-07-06 Dow Agrosciences Llc métodos para síntese de oxipicolinamidas
WO2020208096A1 (en) * 2019-04-10 2020-10-15 Syngenta Crop Protection Ag Fungicidal compositions
WO2024070892A1 (ja) * 2022-09-26 2024-04-04 住友化学株式会社 シクロプロパンカルボン酸エステル化合物及びその用途

Family Cites Families (112)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA714391B (en) * 1970-07-29 1972-04-26 Hoffmann La Roche Benzodiazepine derivatives
DE2415867A1 (de) * 1974-04-02 1975-10-09 Merck Patent Gmbh Phenoxyalkanolderivate und verfahren zu ihrer herstellung
US4051173A (en) * 1974-04-02 1977-09-27 Merck Patent Gesellschaft Mit Beschrankter Haftung Phenoxyalkanol derivatives
US4588735A (en) 1983-02-28 1986-05-13 Chevron Research Company Fungicidal (trihalophenoxy or trihalophenthio) alkylaminoalkyl pyridines and pyrroles
DE3519294A1 (de) 1985-05-30 1986-12-04 Koenig & Bauer AG, 8700 Würzburg Wasserkasten fuer ein feuchtwerk einer offset-rotationsdruckmaschine
FR2649699A1 (fr) 1989-07-13 1991-01-18 Rhone Poulenc Agrochimie 4-phenyl pyrimidine fongicides
IL91418A (en) 1988-09-01 1997-11-20 Rhone Poulenc Agrochimie (hetero) cyclic amide derivatives, process for their preparation and fungicidal compositions containing them
EP0612754B1 (de) 1993-02-25 1998-08-19 Th. Goldschmidt AG Organopolysiloxanpolyether und deren Verwendung als hydrolysestabile Netzmittel in wässrigen Systemen
DK0731795T3 (da) 1993-11-30 2000-05-15 Searle & Co Substituerede pyrazolylbenzensulfonamider til behandling af inflammation
US5466823A (en) 1993-11-30 1995-11-14 G.D. Searle & Co. Substituted pyrazolyl benzenesulfonamides
DE4434637A1 (de) 1994-09-28 1996-04-04 Hoechst Schering Agrevo Gmbh Substituierte Pyridine, Verfahren zu ihrer Herstellung und ihre Verwendung als Schädlingsbekämpfungsmittel und Fungizide
JPH11510788A (ja) 1995-05-24 1999-09-21 ノバルティス アクチェンゲゼルシャフト ピリジン殺菌剤
AR004980A1 (es) 1995-11-29 1999-04-07 Nihon Nohyaku Co Ltd Fungicida para la fruta de cultivo, derivado de fenilalanina comprendido como ingrediente activo en el mismo y metodo para controlar enfermedades enplantas aplicando dicho fungicida.
JP2000509047A (ja) 1996-04-30 2000-07-18 ヘキスト・アクチエンゲゼルシヤフト 3―アルコキシピリジン―2―カルボキサミドエステル類、その製法および薬剤としてのその使用
JPH1045747A (ja) 1996-08-06 1998-02-17 Pola Chem Ind Inc アンチマイシンa系化合物の混合物
JPH1053583A (ja) 1996-08-09 1998-02-24 Mitsubishi Chem Corp ピラゾール化合物およびこれを有効成分とする殺菌、殺虫、殺ダニ剤
GB9622636D0 (en) 1996-10-30 1997-01-08 Scotia Holdings Plc Presentation of bioactives
EP0862856B1 (en) 1997-03-03 2003-06-18 Rohm And Haas Company Pesticide compositions
AU8887898A (en) 1997-08-29 1999-03-22 Meiji Seika Kaisha Ltd. Rice blast control agent and wheat scab control agent
TW491686B (en) 1997-12-18 2002-06-21 Basf Ag Fungicidal mixtures based on amide compounds and tetrachloroisophthalonitrile
WO1999040081A1 (fr) 1998-02-06 1999-08-12 Meiji Seika Kaisha, Ltd. Nouveaux composes antifongiques et leur procede de production
JP4689042B2 (ja) 1998-11-04 2011-05-25 明治製菓株式会社 ピコリン酸アミド誘導体、それを有効成分として含有する有害生物防除剤
WO2000076979A1 (de) 1999-06-09 2000-12-21 Bayer Aktiengesellschaft Pyridincarboxamide und ihre verwendung als pflanzenschutzmittel
KR100743262B1 (ko) 1999-07-20 2007-07-27 다우 아그로사이언시즈 엘엘씨 살균성 헤테로고리 방향족 아미드 및 그 조성물, 사용 및제조방법
US6355660B1 (en) 1999-07-20 2002-03-12 Dow Agrosciences Llc Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation
US20030018052A1 (en) 1999-07-20 2003-01-23 Ricks Michael J. Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation
AU781272B2 (en) 1999-08-20 2005-05-12 Fred Hutchinson Cancer Research Center Compositions and methods for modulating apoptosis in cells over-expressing Bcl-2 family member proteins
US20050239873A1 (en) 1999-08-20 2005-10-27 Fred Hutchinson Cancer Research Center 2 Methoxy antimycin a derivatives and methods of use
ATE397590T1 (de) * 1999-08-20 2008-06-15 Dow Agrosciences Llc Fungizide heterocyclische aromatische amide und deren zusammensetzungen, verfahren zu deren anwendung und herstellung
FR2803592A1 (fr) * 2000-01-06 2001-07-13 Aventis Cropscience Sa Nouveaux derives de l'acide 3-hydroxypicolinique, leur procede de preparation et compositions fongicides les contenant.
US7241804B1 (en) 2000-08-18 2007-07-10 Fred Hutchinson Cancer Research Center Compositions and methods for modulating apoptosis in cells over-expressing Bcl-2 family member proteins
US20020119979A1 (en) 2000-10-17 2002-08-29 Degenhardt Charles Raymond Acyclic compounds and methods for treating multidrug resistance
EP1275653A1 (en) 2001-07-10 2003-01-15 Bayer CropScience S.A. Oxazolopyridines and their use as fungicides
FR2827286A1 (fr) 2001-07-11 2003-01-17 Aventis Cropscience Sa Nouveaux composes fongicides
US6916932B2 (en) 2001-07-31 2005-07-12 Dow Agrosciences Llc Reductive cleavage of the exocyclic ester of UK-2A or its derivatives and products formed therefrom
AU2002341989A1 (en) 2001-10-05 2003-04-22 Dow Agrosciences Llc Process to produce derivatives from uk-2a derivatives
AR037328A1 (es) 2001-10-23 2004-11-03 Dow Agrosciences Llc Compuesto de [7-bencil-2,6-dioxo-1,5-dioxonan-3-il]-4-metoxipiridin-2-carboxamida, composicion que lo comprende y metodo que lo utiliza
KR20060015307A (ko) 2003-05-28 2006-02-16 바스프 악티엔게젤샤프트 벼 병원체 방제를 위한 살진균성 혼합물
US20060167281A1 (en) 2003-07-17 2006-07-27 John Meijer 1,2,4- Trioxepanes as precursors for lactones
DE10347090A1 (de) 2003-10-10 2005-05-04 Bayer Cropscience Ag Synergistische fungizide Wirkstoffkombinationen
PT1751087E (pt) 2004-06-04 2012-09-10 Xenoport Inc Derivados de levodopa e as suas composições e utilizações
GB0419694D0 (en) * 2004-09-06 2004-10-06 Givaudan Sa Anti-bacterial compounds
NZ560376A (en) 2005-02-04 2010-03-26 Mitsui Chemicals Inc Plant pathogen control composition and method
US7927617B2 (en) 2005-04-18 2011-04-19 Basf Aktiengesellschaft Preparation comprising at least one conazole fungicide
WO2007054835A2 (en) 2005-06-21 2007-05-18 Cheminova Agro A/S Synergistic combination of a glyphosate herbicide and a triazole fungicide
EA014099B1 (ru) 2005-08-05 2010-08-30 Басф Се Фунгицидные смеси, содержащие замещенные анилиды 1-метилпиразол-4-ил-карбоновой кислоты
US8008231B2 (en) 2005-10-13 2011-08-30 Momentive Performance Materials Inc. Extreme environment surfactant compositions comprising hydrolysis resistant organomodified disiloxane surfactants
CN1943341B (zh) * 2006-08-04 2012-05-09 华南农业大学 氨基酸与农药的藕合物及其制备方法与作为农药的应用
US7829592B2 (en) 2006-12-21 2010-11-09 Xenoport, Inc. Catechol protected levodopa diester prodrugs, compositions, and methods of use
WO2008105964A1 (en) 2007-02-26 2008-09-04 Stepan Company Adjuvants for agricultural applications
PT2205082E (pt) 2007-09-26 2012-05-02 Basf Se Composições fungicidas ternárias compreendendo boscalide e clorotalonil
CN101969953B (zh) * 2008-01-03 2013-01-09 生物马林药物股份有限公司 用于治疗bh4反应性疾病的喋呤类似物
CN102111999B (zh) 2008-05-30 2016-03-16 陶氏益农公司 控制QoI抗性真菌病原体的方法
CN102245608A (zh) 2008-10-08 2011-11-16 百时美施贵宝公司 吡咯并三嗪酮黑色素浓集激素受体-1拮抗剂
PE20110819A1 (es) * 2008-12-19 2011-11-02 Bristol Myers Squibb Co Compuestos de carbazol carboxamida utiles como inhibidores de cinasa
TWI504598B (zh) 2009-03-20 2015-10-21 Onyx Therapeutics Inc 結晶性三肽環氧酮蛋白酶抑制劑
US8465562B2 (en) 2009-04-14 2013-06-18 Indiana University Research And Technology Corporation Scalable biomass reactor and method
CN101530104B (zh) 2009-04-21 2013-07-31 上虞颖泰精细化工有限公司 一种含有磺酰脲类、吡啶类、氰氟草酯的除草剂组合物及其应用
EP2462134B1 (en) 2009-08-07 2014-05-07 Dow AgroSciences LLC N1-sulfonyl-5-fluoropyrimidinone derivatives
UA112284C2 (uk) 2009-08-07 2016-08-25 ДАУ АГРОСАЙЄНСІЗ ЕлЕлСі Похідні 5-фторпіримідинону
US8470840B2 (en) 2009-09-01 2013-06-25 Dow Agrosciences, Llc. Synergistic fungicidal compositions containing a 5-fluoropyrimidine derivative for fungal control in cereals
WO2011037968A1 (en) 2009-09-22 2011-03-31 Valent U.S.A, Corporation Metconazole compositions and methods of use
UA109416C2 (xx) 2009-10-06 2015-08-25 Стабільні емульсії типу "масло в воді"
BR112012007975A2 (pt) 2009-10-07 2016-03-29 Dow Agrosciences Llc composição fungicida sinergística contendo 5-fluorocitosina para controle fúngico em cereais
JP5905826B2 (ja) 2009-10-07 2016-04-20 ダウ アグロサイエンシィズ エルエルシー 穀類において真菌を制御するための相乗的殺真菌混合物
NZ600886A (en) 2009-12-08 2013-06-28 Basf Se An agrochemical pesticidal mixture for increasing the yield and health of a plant
US9156816B2 (en) 2010-02-26 2015-10-13 Nippon Soda Co., Ltd. Tetrazolyloxime derivative or salt thereof and fungicide
WO2011133875A2 (en) 2010-04-24 2011-10-27 Viamet Pharmaceuticals, Inc. Metalloenzyme inhibitor compounds
US8586550B2 (en) 2010-06-18 2013-11-19 Green Cross Corporation Thiazole derivatives as SGLT2 inhibitors and pharmaceutical composition comprising same
UA111593C2 (uk) 2010-07-07 2016-05-25 Баєр Інтеллекчуел Проперті Гмбх Аміди антранілової кислоти у комбінації з фунгіцидами
BR112013002538A2 (pt) 2010-08-03 2016-05-31 Basf Se composições fungicidas, métodos para controlar fungos fitopatogênicos e proteger as plantas e para a proteção de material de propagação de planta, uso da composição e material de propagação de planta
UA111167C2 (uk) 2010-08-05 2016-04-11 ДАУ АГРОСАЙЄНСІЗ ЕлЕлСі Пестицидні композиції мезорозмірних частинок з підсиленою дією
WO2012016972A2 (en) 2010-08-05 2012-02-09 Bayer Cropscience Ag Active compound combinations
JP2012036143A (ja) 2010-08-10 2012-02-23 Sumitomo Chemical Co Ltd 植物病害防除組成物およびその用途
JP2014503504A (ja) 2010-11-24 2014-02-13 ステマージ バイオテクノロジー エスエー ミトコンドリアの電子伝達系の複合体iiiの活性の阻害剤、及び疾患を治療するためのその使用
CN103635466A (zh) * 2011-04-20 2014-03-12 生物科学管理有限责任公司 芳族酰胺及其用途
JP6013032B2 (ja) 2011-07-08 2016-10-25 石原産業株式会社 殺菌剤組成物及び植物病害の防除方法
EP2804479A4 (en) 2012-01-20 2015-07-22 Viamet Pharmaceuticals Inc METALLOENZYME INHIBITOR COMPOUNDS
TWI568721B (zh) 2012-02-01 2017-02-01 杜邦股份有限公司 殺真菌之吡唑混合物
WO2013169658A1 (en) 2012-05-07 2013-11-14 Dow Agrosciences Llc Use of pro-fungicides of uk-2a for control of soybean rust
WO2013169661A1 (en) 2012-05-07 2013-11-14 Dow Agrosciences Llp Use of pro-fungicides of uk-2a for control of black sigatoka
KR20150013687A (ko) 2012-05-07 2015-02-05 다우 아그로사이언시즈 엘엘씨 살진균제로서 매크로시클릭 피콜린아미드
JP6129300B2 (ja) 2012-05-07 2017-05-17 ダウ アグロサイエンシィズ エルエルシー 殺真菌剤としての大環状ピコリンアミド
BR112014027673A2 (pt) * 2012-05-07 2017-06-27 Dow Agrosciences Llc picolinamidas macrocíclicas como fungicidas
US8900625B2 (en) 2012-12-15 2014-12-02 Nexmed Holdings, Inc. Antimicrobial compounds and methods of use
CN104994859B (zh) 2012-12-28 2018-10-26 阿达玛马克西姆股份有限公司 1-(取代的苯甲酰基)-5-氟-4-亚氨基-3-甲基-3,4-二氢嘧啶-2(1h)-酮衍生物
DK2938191T3 (en) 2012-12-28 2018-05-07 Dow Agrosciences Llc SYNERGISTIC FUNGICIDE MIXTURES FOR FERTILIZER IN GRAIN PLANTS
CL2015001862A1 (es) 2012-12-28 2015-10-02 Dow Agrosciences Llc Derivados de n-(sustitutos)-5-fluoro-4-imino-3-metil-2-oxo-3, 4-dihidropirimidon-1 (2h)-carboxilato
MX2015008444A (es) 2012-12-28 2015-09-23 Dow Agrosciences Llc Derivados de n-(sustituido)-5-flouro-4-imino-3-metil-2-oxo-3,4-dih idropirimidin-1 (2h)-carboximida.
CN104902757B (zh) 2012-12-28 2019-01-08 阿达玛马克西姆股份有限公司 N-(取代的)-5-氟-4-亚氨基-3-甲基-2-氧代-3,4-二氢嘧啶-1(2h)-羧酸酯衍生物
US9750248B2 (en) 2012-12-31 2017-09-05 Dow Agrosciences Llc Synergistic fungicidal compositions
KR20150103175A (ko) 2012-12-31 2015-09-09 다우 아그로사이언시즈 엘엘씨 살진균제로서의 마크로시클릭 피콜린아미드
US9482661B2 (en) 2012-12-31 2016-11-01 Dow Agrosciences Llc Synthesis and use of isotopically labeled macrocyclic compounds
JP6539205B2 (ja) 2013-07-10 2019-07-03 Meiji Seikaファルマ株式会社 ピコリン酸誘導体を含んでなる相乗性植物病害防除用組成物
BR112016006874A2 (pt) 2013-10-01 2017-08-01 Dow Agrosciences Llc uso de picolinamidas macrocíclicas como fungicidas
EP3052491A4 (en) 2013-10-01 2017-05-24 Dow AgroSciences LLC Use of macrocylic picolinamides as fungicides
CN106061257A (zh) 2013-12-26 2016-10-26 美国陶氏益农公司 大环吡啶酰胺作为杀真菌剂的用途
CN106028814A (zh) 2013-12-26 2016-10-12 美国陶氏益农公司 大环吡啶酰胺作为杀真菌剂的用途
CA2933191C (en) 2013-12-31 2022-10-25 Dow Agrosciences Llc Synergistic picolinamide-containing fungicidal mixtures for fungal control in cereals
WO2015171408A1 (en) 2014-05-06 2015-11-12 Dow Agrosciences Llc Macrocyclic picolinamides as fungicides
US9686984B2 (en) 2014-07-08 2017-06-27 Dow Agrosciences Llc Macrocyclic picolinamides as fungicides
TW201625576A (zh) 2014-07-08 2016-07-16 陶氏農業科學公司 作爲殺真菌劑之巨環吡啶醯胺(一)
WO2016007525A1 (en) 2014-07-08 2016-01-14 Dow Agrosciences Llc Macrocyclic picolinamides as a seed treatment
US20160037774A1 (en) 2014-08-08 2016-02-11 Dow Agrosciences Llc Synergistic fungicidal mixtures for fungal control in cereals
CN107205397A (zh) 2014-12-30 2017-09-26 美国陶氏益农公司 具有杀真菌活性的吡啶酰胺化合物的用途
BR112017013653A2 (pt) 2014-12-30 2018-03-13 Dow Agrosciences Llc uso de compostos de picolinamida com atividade fungicida
CN107105662A (zh) 2014-12-30 2017-08-29 美国陶氏益农公司 大环吡啶酰胺作为杀真菌剂的用途
KR20170100547A (ko) 2014-12-30 2017-09-04 다우 아그로사이언시즈 엘엘씨 살진균 활성을 갖는 피콜린아미드
EP3240417A4 (en) 2014-12-30 2018-06-06 Dow Agrosciences LLC Macrocyclic picolinamide compounds with fungicidal activity
RU2702088C2 (ru) 2014-12-30 2019-10-03 ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи Применение соединений пиколинамида в качестве фунгицидов
CN107205385A (zh) 2014-12-30 2017-09-26 美国陶氏益农公司 吡啶酰胺作为杀真菌剂的用途
WO2016109634A1 (en) 2014-12-30 2016-07-07 Dow Agrosciences Llc Fungicidal compositions

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