US3536809A
(en)
|
1969-02-17 |
1970-10-27 |
Alza Corp |
Medication method
|
US3598123A
(en)
|
1969-04-01 |
1971-08-10 |
Alza Corp |
Bandage for administering drugs
|
US3845770A
(en)
|
1972-06-05 |
1974-11-05 |
Alza Corp |
Osmatic dispensing device for releasing beneficial agent
|
US3916899A
(en)
|
1973-04-25 |
1975-11-04 |
Alza Corp |
Osmotic dispensing device with maximum and minimum sizes for the passageway
|
US4008719A
(en)
|
1976-02-02 |
1977-02-22 |
Alza Corporation |
Osmotic system having laminar arrangement for programming delivery of active agent
|
US4270537A
(en)
|
1979-11-19 |
1981-06-02 |
Romaine Richard A |
Automatic hypodermic syringe
|
KR890002631B1
(ko)
|
1984-10-04 |
1989-07-21 |
몬산토 캄파니 |
생물학적으로 활성인 소마토트로핀을 지속적으로 유리하는 조성물
|
IE58110B1
(en)
|
1984-10-30 |
1993-07-14 |
Elan Corp Plc |
Controlled release powder and process for its preparation
|
US4596556A
(en)
|
1985-03-25 |
1986-06-24 |
Bioject, Inc. |
Hypodermic injection apparatus
|
US5023252A
(en)
|
1985-12-04 |
1991-06-11 |
Conrex Pharmaceutical Corporation |
Transdermal and trans-membrane delivery of drugs
|
CA1283827C
(en)
|
1986-12-18 |
1991-05-07 |
Giorgio Cirelli |
Appliance for injection of liquid formulations
|
GB8704027D0
(en)
|
1987-02-20 |
1987-03-25 |
Owen Mumford Ltd |
Syringe needle combination
|
US4992445A
(en)
|
1987-06-12 |
1991-02-12 |
American Cyanamid Co. |
Transdermal delivery of pharmaceuticals
|
US5001139A
(en)
|
1987-06-12 |
1991-03-19 |
American Cyanamid Company |
Enchancers for the transdermal flux of nivadipine
|
US4941880A
(en)
|
1987-06-19 |
1990-07-17 |
Bioject, Inc. |
Pre-filled ampule and non-invasive hypodermic injection device assembly
|
US4790824A
(en)
|
1987-06-19 |
1988-12-13 |
Bioject, Inc. |
Non-invasive hypodermic injection device
|
US4940460A
(en)
|
1987-06-19 |
1990-07-10 |
Bioject, Inc. |
Patient-fillable and non-invasive hypodermic injection device assembly
|
US5339163A
(en)
|
1988-03-16 |
1994-08-16 |
Canon Kabushiki Kaisha |
Automatic exposure control device using plural image plane detection areas
|
US5073543A
(en)
|
1988-07-21 |
1991-12-17 |
G. D. Searle & Co. |
Controlled release formulations of trophic factors in ganglioside-lipsome vehicle
|
FR2638359A1
(fr)
|
1988-11-03 |
1990-05-04 |
Tino Dalto |
Guide de seringue avec reglage de la profondeur de penetration de l'aiguille dans la peau
|
GB8827305D0
(en)
|
1988-11-23 |
1988-12-29 |
British Bio Technology |
Compounds
|
IT1229203B
(it)
|
1989-03-22 |
1991-07-25 |
Bioresearch Spa |
Impiego di acido 5 metiltetraidrofolico, di acido 5 formiltetraidrofolico e dei loro sali farmaceuticamente accettabili per la preparazione di composizioni farmaceutiche in forma a rilascio controllato attive nella terapia dei disturbi mentali organici e composizioni farmaceutiche relative.
|
PH30995A
(en)
|
1989-07-07 |
1997-12-23 |
Novartis Inc |
Sustained release formulations of water soluble peptides.
|
US5120548A
(en)
|
1989-11-07 |
1992-06-09 |
Merck & Co., Inc. |
Swelling modulated polymeric drug delivery device
|
US5064413A
(en)
|
1989-11-09 |
1991-11-12 |
Bioject, Inc. |
Needleless hypodermic injection device
|
US5312335A
(en)
|
1989-11-09 |
1994-05-17 |
Bioject Inc. |
Needleless hypodermic injection device
|
US5733566A
(en)
|
1990-05-15 |
1998-03-31 |
Alkermes Controlled Therapeutics Inc. Ii |
Controlled release of antiparasitic agents in animals
|
US5190521A
(en)
|
1990-08-22 |
1993-03-02 |
Tecnol Medical Products, Inc. |
Apparatus and method for raising a skin wheal and anesthetizing skin
|
US5527288A
(en)
|
1990-12-13 |
1996-06-18 |
Elan Medical Technologies Limited |
Intradermal drug delivery device and method for intradermal delivery of drugs
|
GB9118204D0
(en)
|
1991-08-23 |
1991-10-09 |
Weston Terence E |
Needle-less injector
|
SE9102652D0
(sv)
|
1991-09-13 |
1991-09-13 |
Kabi Pharmacia Ab |
Injection needle arrangement
|
US5580578A
(en)
|
1992-01-27 |
1996-12-03 |
Euro-Celtique, S.A. |
Controlled release formulations coated with aqueous dispersions of acrylic polymers
|
US5328483A
(en)
|
1992-02-27 |
1994-07-12 |
Jacoby Richard M |
Intradermal injection device with medication and needle guard
|
ATE205542T1
(de)
|
1992-03-04 |
2001-09-15 |
Univ California |
Vergleichende genomhybridisierung
|
US5383851A
(en)
|
1992-07-24 |
1995-01-24 |
Bioject Inc. |
Needleless hypodermic injection device
|
US5569189A
(en)
|
1992-09-28 |
1996-10-29 |
Equidyne Systems, Inc. |
hypodermic jet injector
|
US5334144A
(en)
|
1992-10-30 |
1994-08-02 |
Becton, Dickinson And Company |
Single use disposable needleless injector
|
TW333456B
(en)
|
1992-12-07 |
1998-06-11 |
Takeda Pharm Ind Co Ltd |
A pharmaceutical composition of sustained-release preparation the invention relates to a pharmaceutical composition of sustained-release preparation which comprises a physiologically active peptide.
|
US5455258A
(en)
|
1993-01-06 |
1995-10-03 |
Ciba-Geigy Corporation |
Arylsulfonamido-substituted hydroxamic acids
|
US5591767A
(en)
|
1993-01-25 |
1997-01-07 |
Pharmetrix Corporation |
Liquid reservoir transdermal patch for the administration of ketorolac
|
US6087324A
(en)
|
1993-06-24 |
2000-07-11 |
Takeda Chemical Industries, Ltd. |
Sustained-release preparation
|
WO1995024176A1
(en)
|
1994-03-07 |
1995-09-14 |
Bioject, Inc. |
Ampule filling device
|
US5466220A
(en)
|
1994-03-08 |
1995-11-14 |
Bioject, Inc. |
Drug vial mixing and transfer device
|
IT1270594B
(it)
|
1994-07-07 |
1997-05-07 |
Recordati Chem Pharm |
Composizione farmaceutica a rilascio controllato di moguisteina in sospensione liquida
|
US5599302A
(en)
|
1995-01-09 |
1997-02-04 |
Medi-Ject Corporation |
Medical injection system and method, gas spring thereof and launching device using gas spring
|
US5863949A
(en)
|
1995-03-08 |
1999-01-26 |
Pfizer Inc |
Arylsulfonylamino hydroxamic acid derivatives
|
CA2218503C
(en)
|
1995-04-20 |
2001-07-24 |
Pfizer Inc. |
Arylsulfonyl hydroxamic acid derivatives
|
US5730723A
(en)
|
1995-10-10 |
1998-03-24 |
Visionary Medical Products Corporation, Inc. |
Gas pressured needle-less injection device and method
|
ATE268591T1
(de)
|
1995-06-27 |
2004-06-15 |
Takeda Chemical Industries Ltd |
Verfahren zur herstellung von zubereitungen mit verzögerter freisetzung
|
TW448055B
(en)
|
1995-09-04 |
2001-08-01 |
Takeda Chemical Industries Ltd |
Method of production of sustained-release preparation
|
JP2909418B2
(ja)
|
1995-09-18 |
1999-06-23 |
株式会社資生堂 |
薬物の遅延放出型マイクロスフイア
|
DK0780386T3
(da)
|
1995-12-20 |
2003-02-03 |
Hoffmann La Roche |
Matrixmetalloproteaseinhibitorer
|
US5893397A
(en)
|
1996-01-12 |
1999-04-13 |
Bioject Inc. |
Medication vial/syringe liquid-transfer apparatus
|
US5980945A
(en)
|
1996-01-16 |
1999-11-09 |
Societe De Conseils De Recherches Et D'applications Scientifique S.A. |
Sustained release drug formulations
|
GB9607549D0
(en)
|
1996-04-11 |
1996-06-12 |
Weston Medical Ltd |
Spring-powered dispensing device
|
US6264970B1
(en)
|
1996-06-26 |
2001-07-24 |
Takeda Chemical Industries, Ltd. |
Sustained-release preparation
|
JP3195756B2
(ja)
|
1996-07-04 |
2001-08-06 |
公子 吉水 |
潤滑補助体
|
TR199900066T2
(xx)
|
1996-07-18 |
1999-04-21 |
Pfizer Inc. |
Matriks metalloproteazlar�n fosfinat bazl� inhibit�rleri
|
IL128189A0
(en)
|
1996-08-23 |
1999-11-30 |
Pfizer |
Arylsulfonylamino hydroxamic acid derivatives
|
US6419961B1
(en)
|
1996-08-29 |
2002-07-16 |
Takeda Chemical Industries, Ltd. |
Sustained release microcapsules of a bioactive substance and a biodegradable polymer
|
CA2217134A1
(en)
|
1996-10-09 |
1998-04-09 |
Sumitomo Pharmaceuticals Co., Ltd. |
Sustained release formulation
|
DE69730093T2
(de)
|
1996-10-31 |
2006-07-20 |
Takeda Pharmaceutical Co. Ltd. |
Zubereitung mit verzögerter Freisetzung
|
WO1998027980A2
(en)
|
1996-12-20 |
1998-07-02 |
Takeda Chemical Industries, Ltd. |
Method of producing a sustained-release preparation
|
US6077864A
(en)
|
1997-01-06 |
2000-06-20 |
Pfizer Inc. |
Cyclic sulfone derivatives
|
US5891474A
(en)
|
1997-01-29 |
1999-04-06 |
Poli Industria Chimica, S.P.A. |
Time-specific controlled release dosage formulations and method of preparing same
|
PL335027A1
(en)
|
1997-02-03 |
2000-03-27 |
Pfizer Prod Inc |
Derivatives of arylsulphonylamino hydroxamic acid
|
CA2279863A1
(en)
|
1997-02-07 |
1998-08-13 |
Pfizer Inc. |
N-hydroxy-beta-sulfonyl-propionamide derivatives and their use as inhibitors of matrix metalloproteinases
|
BR9807678A
(pt)
|
1997-02-11 |
2000-02-15 |
Pfizer |
Derivados de ácidos arilsulfonil-hidroxâmicos
|
US5993412A
(en)
|
1997-05-19 |
1999-11-30 |
Bioject, Inc. |
Injection apparatus
|
GB9725782D0
(en)
|
1997-12-05 |
1998-02-04 |
Pfizer Ltd |
Therapeutic agents
|
IT1298087B1
(it)
|
1998-01-08 |
1999-12-20 |
Fiderm S R L |
Dispositivo per il controllo della profondita' di penetrazione di un ago, in particolare applicabile ad una siringa per iniezioni
|
GB9801690D0
(en)
|
1998-01-27 |
1998-03-25 |
Pfizer Ltd |
Therapeutic agents
|
US6613358B2
(en)
|
1998-03-18 |
2003-09-02 |
Theodore W. Randolph |
Sustained-release composition including amorphous polymer
|
US6432970B2
(en)
|
1998-04-09 |
2002-08-13 |
Johns Hopkins University School Of Medicine |
Inhibitors of hedgehog signaling pathways, compositions and uses related thereto
|
PA8469401A1
(es)
|
1998-04-10 |
2000-05-24 |
Pfizer Prod Inc |
Derivados biciclicos del acido hidroxamico
|
PA8469501A1
(es)
|
1998-04-10 |
2000-09-29 |
Pfizer Prod Inc |
Hidroxamidas del acido (4-arilsulfonilamino)-tetrahidropiran-4-carboxilico
|
KR19990085365A
(ko)
|
1998-05-16 |
1999-12-06 |
허영섭 |
지속적으로 약물 조절방출이 가능한 생분해성 고분자 미립구 및그 제조방법
|
US6927024B2
(en)
|
1998-11-30 |
2005-08-09 |
Genentech, Inc. |
PCR assay
|
US6248363B1
(en)
|
1999-11-23 |
2001-06-19 |
Lipocine, Inc. |
Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
|
ES2234662T3
(es)
|
1999-09-16 |
2005-07-01 |
Curis, Inc. |
Mediadores de rutas de señalizacion hedgehog, composiciones y usos relacionados con los mismos.
|
US20070021493A1
(en)
|
1999-09-16 |
2007-01-25 |
Curis, Inc. |
Mediators of hedgehog signaling pathways, compositions and uses related thereto
|
JP5420128B2
(ja)
|
1999-10-13 |
2014-02-19 |
ジョンズ ホプキンス ユニバーシティ スクール オブ メディシン |
ヘッジホッグ経路の調節物質、並びにそれに関する組成物及び利用法
|
WO2001026644A2
(en)
|
1999-10-14 |
2001-04-19 |
Curis, Inc. |
Mediators of hedgehog signaling pathways, compositions and uses related thereto
|
AU3074001A
(en)
|
1999-12-09 |
2001-06-18 |
Advanced Research And Technology Institute, Inc. |
Fluorescent in situ rt-pcr
|
IL133809A0
(en)
|
1999-12-30 |
2001-04-30 |
Yeda Res & Dev |
Steroidal alkaloids and pharmaceutical compositions comprising them
|
DE60113823T3
(de)
|
2000-03-30 |
2010-07-01 |
Curis, Inc., Cambridge |
Kleine organische moleküle als regulatoren der zellproliferation
|
AU2002247248B2
(en)
|
2001-03-02 |
2007-07-05 |
University Of Pittsburgh Of The Commonwealth System Of Higher Education |
PCR method
|
ATE443518T1
(de)
|
2001-07-27 |
2009-10-15 |
Curis Inc |
Vermittler von igel-signalpfaden, zusammensetzungen und relevante verwendungszwecke
|
WO2003030902A1
(en)
|
2001-10-09 |
2003-04-17 |
Tularik Inc. |
Imidazole derivates as anti-inflammatory agents
|
US20030113828A1
(en)
|
2001-11-09 |
2003-06-19 |
Ginsberg Mark H. |
Compositions and methods for modulating Syk function
|
US20030158195A1
(en)
|
2001-12-21 |
2003-08-21 |
Cywin Charles L. |
1,6 naphthyridines useful as inhibitors of SYK kinase
|
AU2003231032B2
(en)
|
2002-04-22 |
2008-07-10 |
Johns Hopkins University School Of Medicine |
Modulators of hedgehog signaling pathways, compositions and uses related thereto
|
AU2003265853A1
(en)
|
2002-08-29 |
2004-03-19 |
Curis, Inc. |
Hedgehog antagonists, methods and uses related thereto
|
AU2003270701B2
(en)
|
2002-10-31 |
2009-11-12 |
Amgen Inc. |
Antiinflammation agents
|
FR2850022B1
(fr)
|
2003-01-22 |
2006-09-08 |
Centre Nat Rech Scient |
Nouvelle utilisation de la mifepristone et de ses derives comme modulateurs de la voie de signalisation des proteines hedgehog et ses applications
|
EP2371835A1
(en)
|
2003-07-03 |
2011-10-05 |
The Trustees Of The University Of Pennsylvania |
Inhibition of syk kinase expression
|
WO2005013800A2
(en)
|
2003-07-15 |
2005-02-17 |
The Johns Hopkins University |
Elevated hedgehog pathway activity in digestive system tumors, and methods of treating digestive system tumors having elevated hedgehog pathway activity
|
WO2005016348A1
(en)
|
2003-08-14 |
2005-02-24 |
Icos Corporation |
Method of inhibiting immune responses stimulated by an endogenous factor
|
GB0321710D0
(en)
|
2003-09-16 |
2003-10-15 |
Novartis Ag |
Organic compounds
|
US8067608B2
(en)
|
2003-09-29 |
2011-11-29 |
The Johns Hopkins University |
Hedgehog pathway antagonists
|
US20080095761A1
(en)
|
2003-10-01 |
2008-04-24 |
The Johns Hopkins University |
Hedgehog Signaling in Prostate Regeneration Neoplasia and Metastasis
|
WO2005042700A2
(en)
|
2003-10-20 |
2005-05-12 |
The Johns Hopkins University |
Use of hedgehog pathway inhibitors in small-cell lung cancer
|
WO2005049832A2
(en)
|
2003-11-14 |
2005-06-02 |
Yale University |
FcϜRIIA-SPECIFIC NUCLEIC ACID INTERFERENCE
|
US7122799B2
(en)
|
2003-12-18 |
2006-10-17 |
Palo Alto Research Center Incorporated |
LED or laser enabled real-time PCR system and spectrophotometer
|
US8057815B2
(en)
|
2004-04-19 |
2011-11-15 |
Portola Pharmaceuticals, Inc. |
Methods of treatment with Syk inhibitors
|
JP4903133B2
(ja)
|
2004-04-30 |
2012-03-28 |
ジェネンテック,インコーポレイティド |
ヘッジホッグシグナル伝達のキノキサリン阻害剤
|
PT3153514T
(pt)
|
2004-05-13 |
2021-06-25 |
Icos Corp |
Quinazolinonas como inibidoras da fosfatidilinositol 3-quinase delta humana
|
JP5204486B2
(ja)
|
2004-08-27 |
2013-06-05 |
インフィニティ ファーマスーティカルズ、インク. |
シクロパミンアナログ及びその使用方法
|
JP5143558B2
(ja)
|
2004-09-02 |
2013-02-13 |
ジェネンテック,インコーポレイティド |
ヘッジホッグシグナル伝達のピリジルインヒビター
|
RU2007119637A
(ru)
|
2004-10-28 |
2008-12-10 |
Айрм Ллк (Bm) |
Соединения и композиции в качестве модуляторов hedgehog-пути
|
KR100917511B1
(ko)
|
2005-02-28 |
2009-09-16 |
니뽄 다바코 산교 가부시키가이샤 |
Syk 저해 활성을 갖는 신규한 아미노피리딘 화합물
|
EP1945202A2
(en)
|
2005-11-11 |
2008-07-23 |
Licentia OY |
Mammalian hedgehog signaling inhiabitors
|
JP5225857B2
(ja)
|
2005-11-14 |
2013-07-03 |
ジェネンテック,インコーポレイティド |
ヘッジホッグシグナル伝達のビスアミド阻害剤
|
WO2007107469A1
(en)
|
2006-03-20 |
2007-09-27 |
F. Hoffmann-La Roche Ag |
Methods of inhibiting btk and syk protein kinases
|
RU2008144805A
(ru)
|
2006-04-14 |
2010-05-20 |
Новартис АГ (CH) |
Применение биарилкарбоксамидов в лечении заболеваний, связанных с hedgehog-путем
|
UA93548C2
(uk)
|
2006-05-05 |
2011-02-25 |
Айерем Елелсі |
Сполуки та композиції як модулятори хеджхогівського сигнального шляху
|
PL2026775T3
(pl)
|
2006-05-09 |
2015-12-31 |
Novaremed Ltd |
Zastosowanie inhibitorów kinazy tyrozynowej Syk w leczeniu komórkowych zaburzeń proliferacyjnych
|
US20110021513A1
(en)
|
2006-09-07 |
2011-01-27 |
Biogen Idec Ma Inc. |
Modulators of interleukin-1 receptor-associated kinase
|
CA2667821A1
(en)
|
2006-10-31 |
2008-06-12 |
Government Of The United States Of America, Represented By The Secretary , Department Of Health And Human Services |
Smoothened polypeptides and methods of use
|
BRPI0720546A2
(pt)
|
2006-12-14 |
2015-06-23 |
Daiichi Sankyo Co Ltd |
Composto, inibidor, medicamento, agente antitumor, composição farmacêutica, método para tratar câncer, e, uso do composto
|
TWI433674B
(zh)
|
2006-12-28 |
2014-04-11 |
Infinity Discovery Inc |
環杷明(cyclopamine)類似物類
|
EP2129677B1
(en)
|
2007-03-07 |
2014-12-17 |
Infinity Discovery, Inc. |
Heterocyclic cyclopamine analogs and methods of use thereof
|
CN104193797A
(zh)
|
2007-03-07 |
2014-12-10 |
无限发现股份有限公司 |
环杷明内酰胺类似物及其使用方法
|
MX2009009786A
(es)
|
2007-03-14 |
2009-09-24 |
Exelixis Inc |
Inhibidores de la via de hedgehog.
|
AR065718A1
(es)
|
2007-03-15 |
2009-06-24 |
Novartis Ag |
Compuestos heterociclicos nitrogenados,utiles en el diagnostico y tratamiento de trastornos hiperproliferativos.
|
US20090054517A1
(en)
|
2007-04-20 |
2009-02-26 |
Lubahn Dennis B |
Phytoestrogens As Regulators Of Hedgehog Signaling And Methods Of Their Use In Cancer Treatment
|
US20090012031A1
(en)
|
2007-07-03 |
2009-01-08 |
The Regents Of The University Of Michigan |
EZH2 Cancer Markers
|
NZ586121A
(en)
|
2007-12-13 |
2012-03-30 |
Siena Biotech Spa |
Benzimidazole derivatives as hedgehog pathway antagonists and therapeutic applications thereof
|
US8193182B2
(en)
|
2008-01-04 |
2012-06-05 |
Intellikine, Inc. |
Substituted isoquinolin-1(2H)-ones, and methods of use thereof
|
EP3613743B1
(en)
|
2008-01-04 |
2022-03-16 |
Intellikine, LLC |
Processes for the preparation of 1h-pyrazolo[3,4-d]pyrimidin-4-amine derivatives
|
WO2009088086A1
(ja)
|
2008-01-10 |
2009-07-16 |
Asahi Glass Company, Limited |
ガラス、発光装置用の被覆材および発光装置
|
WO2009089598A2
(en)
|
2008-01-18 |
2009-07-23 |
Katholieke Universiteit Leuven |
Msmb-gene methylation based diagnosis, staging and prognosis of prostate cancer
|
US8637542B2
(en)
|
2008-03-14 |
2014-01-28 |
Intellikine, Inc. |
Kinase inhibitors and methods of use
|
FR2929851B1
(fr)
|
2008-04-09 |
2012-11-30 |
Centre Nat Rech Scient |
Molecules inhibant une voie metabolique impliquant la proteine tyrosine kinase syk et procede d'identification de ces molecules
|
BRPI0910921B1
(pt)
|
2008-04-16 |
2022-06-21 |
Portola Pharmaceuticals, Inc |
Inibidores de proteína syk quinase, composição farmacêutica, kit e usos dos referidos inibidores
|
CN102124009B
(zh)
|
2008-07-08 |
2014-07-23 |
因特利凯公司 |
激酶抑制剂及其使用方法
|
EP2346508B1
(en)
|
2008-09-26 |
2016-08-24 |
Intellikine, LLC |
Heterocyclic kinase inhibitors
|
US9107942B2
(en)
|
2008-10-31 |
2015-08-18 |
University Of Rochester |
Methods of diagnosing and treating fibrosis
|
KR20170060179A
(ko)
|
2008-11-13 |
2017-05-31 |
길리아드 칼리스토가 엘엘씨 |
혈액 종양에 대한 요법
|
JP5696052B2
(ja)
|
2008-12-08 |
2015-04-08 |
ギリアード コネチカット, インコーポレイテッド |
イミダゾピラジンsyk阻害剤
|
US8450321B2
(en)
|
2008-12-08 |
2013-05-28 |
Gilead Connecticut, Inc. |
6-(1H-indazol-6-yl)-N-[4-(morpholin-4-yl)phenyl]imidazo-[1,2-A]pyrazin-8-amine, or a pharmaceutically acceptable salt thereof, as a SYK inhibitor
|
MX2011007499A
(es)
|
2009-01-13 |
2011-08-04 |
Glaxo Group Ltd |
Derivados de pirimidin-carboxamida como inhibidores de la cinasa syk.
|
GB2480028B
(en)
|
2009-02-04 |
2013-07-10 |
Univ Georgia |
Methods of inhibiting fibrogenesis and treating fibrotic disease
|
SG182247A1
(en)
|
2009-05-27 |
2012-08-30 |
Hoffmann La Roche |
Bicyclic indole-pyrimidine pi3k inhibitor compounds selective for p110 delta, and methods of use
|
KR20130026364A
(ko)
|
2009-05-27 |
2013-03-13 |
제넨테크, 인크. |
P110 델타에 대해 선택적인 비시클릭 피리미딘 pi3k 억제제 화합물 및 사용 방법
|
US8377945B2
(en)
|
2009-06-15 |
2013-02-19 |
Rigel Pharmaceuticals Inc. |
Small molecule inhibitors of spleen tyrosine kinase (SYK)
|
TW201105669A
(en)
|
2009-07-30 |
2011-02-16 |
Irm Llc |
Compounds and compositions as Syk kinase inhibitors
|
WO2011014795A2
(en)
|
2009-07-30 |
2011-02-03 |
Irm Llc |
Compounds and compositions as syk kinase inhibitors
|
AU2010300719A1
(en)
|
2009-09-29 |
2012-05-03 |
Xcovery Holding Company Llc |
PI3K (delta) selective inhibitors
|
CN102858767B
(zh)
|
2009-12-17 |
2015-08-19 |
默沙东公司 |
作为syk抑制剂的氨基嘧啶
|
US8735417B2
(en)
|
2009-12-17 |
2014-05-27 |
Merck Sharp & Dohme Corp. |
Aminopyrimidines as Syk inhibitors
|
MX2012007402A
(es)
|
2009-12-23 |
2012-08-23 |
Takeda Pharmaceutical |
Pirrolidinonas heteroaromaticas fusionadas como inhibidores de tirosina cinasa esplenica (syk).
|
WO2011103016A2
(en)
|
2010-02-19 |
2011-08-25 |
The Regents Of The University Of Michigan |
Compositions and methods for inhibiting ezh2
|
GB201007203D0
(en)
|
2010-04-29 |
2010-06-16 |
Glaxo Group Ltd |
Novel compounds
|
US8604032B2
(en)
|
2010-05-21 |
2013-12-10 |
Infinity Pharmaceuticals, Inc. |
Chemical compounds, compositions and methods for kinase modulation
|
CN107898791A
(zh)
*
|
2010-06-03 |
2018-04-13 |
药品循环有限责任公司 |
布鲁顿酪氨酸激酶(btk)抑制剂的应用
|
US20110306622A1
(en)
*
|
2010-06-11 |
2011-12-15 |
Calitoga Pharmaceuticals, Inc. |
Methods of treating hematological disorders with quinazolinone compounds in selected subjects
|
US20130195843A1
(en)
|
2010-06-23 |
2013-08-01 |
British Columbia Cancer Agency Branch |
Biomarkers for Non-Hodgkin Lymphomas and Uses Thereof
|
US9175331B2
(en)
|
2010-09-10 |
2015-11-03 |
Epizyme, Inc. |
Inhibitors of human EZH2, and methods of use thereof
|
DK2614369T3
(en)
|
2010-09-10 |
2016-05-02 |
Epizyme Inc |
METHOD FOR DETERMINING THE SUITABILITY OF HUMAN EZH2 INHIBITORS TREATED
|
US8846928B2
(en)
|
2010-11-01 |
2014-09-30 |
Portola Pharmaceuticals, Inc. |
Benzamides and nicotinamides as Syk modulators
|
TWI674262B
(zh)
*
|
2011-01-10 |
2019-10-11 |
美商英菲尼提製藥股份有限公司 |
製備異喹啉酮之方法及異喹啉酮之固體形式
|
US20130004481A1
(en)
*
|
2011-01-12 |
2013-01-03 |
Boehringer Ingelheim International Gmbh |
Anticancer therapy
|
KR20140025500A
(ko)
|
2011-05-04 |
2014-03-04 |
머크 샤프 앤드 돔 코포레이션 |
아미노-피리딘-함유 비장 티로신 키나제 (Syk) 억제제
|
CN103889987B
(zh)
*
|
2011-07-19 |
2016-09-14 |
默沙东有限责任公司 |
作为btk抑制剂的选择的咪唑并吡嗪类
|
AU2012284088B2
(en)
|
2011-07-19 |
2015-10-08 |
Infinity Pharmaceuticals Inc. |
Heterocyclic compounds and uses thereof
|
KR20140063605A
(ko)
|
2011-07-19 |
2014-05-27 |
인피니티 파마슈티칼스, 인코포레이티드 |
헤테로사이클릭 화합물 및 그의 용도
|
RU2014111823A
(ru)
|
2011-08-29 |
2015-10-10 |
Инфинити Фармасьютикалз, Инк. |
Гетероциклические соединения и их применения
|
BR112014009276A8
(pt)
*
|
2011-10-19 |
2017-06-20 |
Pharmacyclics Inc |
uso de inibidores de tirosina quinase de bruton (btk)
|
MY169987A
(en)
|
2012-07-04 |
2019-06-19 |
Rhizen Pharmaceuticals Sa |
Selective pi3k delta inhibitors
|
MX2015001081A
(es)
*
|
2012-07-24 |
2015-10-14 |
Pharmacyclics Inc |
Mutaciones asociadas a resistencia a inhibidores de la tirosina cinasa de bruton (btk).
|
NZ744567A
(en)
*
|
2012-11-01 |
2020-03-27 |
Infinity Pharmaceuticals Inc |
Treatment of cancers using pi3 kinase isoform modulators
|