JO3235B1 - مركبات بيررولوبيريميدين و استعمالاتها - Google Patents

مركبات بيررولوبيريميدين و استعمالاتها

Info

Publication number
JO3235B1
JO3235B1 JOP/2007/0193A JOP20070193A JO3235B1 JO 3235 B1 JO3235 B1 JO 3235B1 JO P20070193 A JOP20070193 A JO P20070193A JO 3235 B1 JO3235 B1 JO 3235B1
Authority
JO
Jordan
Prior art keywords
useful
pyrrolopyrimidine compounds
compounds
organic compounds
pyrrolopyrimidine
Prior art date
Application number
JOP/2007/0193A
Other languages
English (en)
Inventor
Thoma Gebhard
Thomas Brain Christopher
Je Sung Moo
Original Assignee
Astex Therapeutics Ltd
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38779335&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JO3235(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astex Therapeutics Ltd, Novartis Ag filed Critical Astex Therapeutics Ltd
Application granted granted Critical
Publication of JO3235B1 publication Critical patent/JO3235B1/ar

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/18—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
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    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
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    • A61P25/00—Drugs for disorders of the nervous system
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P3/00—Drugs for disorders of the metabolism
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    • A61P3/00—Drugs for disorders of the metabolism
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
    • A—HUMAN NECESSITIES
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/24—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one nitrogen and one sulfur atom

Abstract

الاختراع الحالي يصف مركبات عضوية مفيدة للعلاج, منع, و/او المعالجة الوقائية من الامراض , و بخاصة مركبات بيررولوبيريميدين و مشتقاتها قد تم وصفها حيث تثبط كينازات البروتين . المركبات العضوية تعتبر مفيدة لعلاج امراض التكاثر.
JOP/2007/0193A 2006-05-26 2007-05-23 مركبات بيررولوبيريميدين و استعمالاتها JO3235B1 (ar)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US80860506P 2006-05-26 2006-05-26

Publications (1)

Publication Number Publication Date
JO3235B1 true JO3235B1 (ar) 2018-03-08

Family

ID=38779335

Family Applications (1)

Application Number Title Priority Date Filing Date
JOP/2007/0193A JO3235B1 (ar) 2006-05-26 2007-05-23 مركبات بيررولوبيريميدين و استعمالاتها

Country Status (38)

Country Link
US (2) US8324225B2 (ar)
EP (1) EP2029145B1 (ar)
JP (2) JP2009538341A (ar)
KR (1) KR101466412B1 (ar)
CN (1) CN101594871B (ar)
AR (2) AR061124A1 (ar)
AU (1) AU2007267645C1 (ar)
BR (1) BRPI0712816B8 (ar)
CA (1) CA2652044C (ar)
CL (1) CL2007001504A1 (ar)
CR (1) CR10433A (ar)
CU (1) CU23831B1 (ar)
EA (1) EA016301B1 (ar)
EC (1) ECSP088910A (ar)
ES (1) ES2623133T3 (ar)
GE (1) GEP20115283B (ar)
GT (1) GT200800258A (ar)
HN (1) HN2008001752A (ar)
HR (1) HRP20170631T1 (ar)
IL (1) IL195086A (ar)
JO (1) JO3235B1 (ar)
MA (1) MA30557B1 (ar)
ME (1) ME00486B (ar)
MX (1) MX2008015076A (ar)
MY (1) MY150650A (ar)
NO (1) NO343182B1 (ar)
NZ (1) NZ572549A (ar)
PE (1) PE20080263A1 (ar)
PL (1) PL2029145T3 (ar)
PT (1) PT2029145T (ar)
SG (1) SG172632A1 (ar)
SM (1) SMP200800069B (ar)
TN (1) TNSN08481A1 (ar)
TW (1) TWI398252B (ar)
UA (1) UA95632C2 (ar)
UY (1) UY30369A1 (ar)
WO (1) WO2007140222A2 (ar)
ZA (1) ZA200809382B (ar)

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HRP20170631T1 (hr) 2017-08-11
WO2007140222A2 (en) 2007-12-06
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PE20080263A1 (es) 2008-05-12
BRPI0712816A2 (pt) 2012-10-23
TNSN08481A1 (en) 2010-04-14
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US20090318441A1 (en) 2009-12-24
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AU2007267645A1 (en) 2007-12-06
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US8324225B2 (en) 2012-12-04
ECSP088910A (es) 2008-12-30
CN101594871A (zh) 2009-12-02
WO2007140222A3 (en) 2008-08-07
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GEP20115283B (en) 2011-09-12
MA30557B1 (fr) 2009-07-01
IL195086A0 (en) 2009-08-03
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UY30369A1 (es) 2008-01-02
AR061124A1 (es) 2008-08-06
CL2007001504A1 (es) 2008-05-09
AR108179A2 (es) 2018-07-25
IL195086A (en) 2015-10-29
AU2007267645C1 (en) 2012-07-12
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