IL151045A0 - 2-benzothiazolyl urea derivatives and their use as protein kinase inhibitors - Google Patents
2-benzothiazolyl urea derivatives and their use as protein kinase inhibitorsInfo
- Publication number
- IL151045A0 IL151045A0 IL15104501A IL15104501A IL151045A0 IL 151045 A0 IL151045 A0 IL 151045A0 IL 15104501 A IL15104501 A IL 15104501A IL 15104501 A IL15104501 A IL 15104501A IL 151045 A0 IL151045 A0 IL 151045A0
- Authority
- IL
- Israel
- Prior art keywords
- protein kinase
- kinase inhibitors
- urea derivatives
- benzothiazolyl urea
- benzothiazolyl
- Prior art date
Links
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- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
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- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
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- C—CHEMISTRY; METALLURGY
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- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
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- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D277/82—Nitrogen atoms
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
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- C—CHEMISTRY; METALLURGY
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
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- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
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- C07D487/08—Bridged systems
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- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
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US18084100P | 2000-02-07 | 2000-02-07 | |
PCT/US2001/003803 WO2001057008A1 (fr) | 2000-02-07 | 2001-02-06 | Derives de 2-benzothiazolyle uree et leur utilisation en tant qu'inhibiteurs de proteine kinase |
Publications (1)
Publication Number | Publication Date |
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IL151045A0 true IL151045A0 (en) | 2003-04-10 |
Family
ID=22661941
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL15104501A IL151045A0 (en) | 2000-02-07 | 2001-02-06 | 2-benzothiazolyl urea derivatives and their use as protein kinase inhibitors |
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US (1) | US7091227B2 (fr) |
EP (1) | EP1254123A1 (fr) |
JP (1) | JP2003521543A (fr) |
KR (1) | KR20020084116A (fr) |
CN (1) | CN1422262A (fr) |
AR (1) | AR030189A1 (fr) |
AU (1) | AU2001236698A1 (fr) |
BG (1) | BG107062A (fr) |
BR (1) | BR0108085A (fr) |
CA (1) | CA2398754A1 (fr) |
HU (1) | HUP0300359A2 (fr) |
IL (1) | IL151045A0 (fr) |
MX (1) | MXPA02007632A (fr) |
NO (1) | NO20023713L (fr) |
PL (1) | PL357099A1 (fr) |
SK (1) | SK12712002A3 (fr) |
WO (1) | WO2001057008A1 (fr) |
ZA (1) | ZA200206235B (fr) |
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JPS57175189A (en) | 1981-04-21 | 1982-10-28 | Kyowa Hakko Kogyo Co Ltd | Benzothiazole derivative and its preparation |
US4966849A (en) * | 1985-09-20 | 1990-10-30 | President And Fellows Of Harvard College | CDNA and genes for human angiogenin (angiogenesis factor) and methods of expression |
JPS62187842A (ja) | 1985-10-25 | 1987-08-17 | Konishiroku Photo Ind Co Ltd | ハロゲン化銀写真感光材料 |
US5217999A (en) * | 1987-12-24 | 1993-06-08 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Styryl compounds which inhibit EGF receptor protein tyrosine kinase |
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US5302606A (en) * | 1990-04-16 | 1994-04-12 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Styryl-substituted pyridyl compounds which inhibit EGF receptor tyrosine kinase |
CA2102780C (fr) | 1991-05-10 | 2007-01-09 | Alfred P. Spada | Composes de type bis-monoaryle, aryle bicyclique et (ou) heteroaryle inhibant l'activite de tyrosine kinase des recepteurs de l'egf et (ou) du pdgf |
JPH06503095A (ja) | 1991-05-29 | 1994-04-07 | ファイザー・インコーポレーテッド | 三環式ポリヒドロキシ系のチロシンキナーゼ阻害薬 |
AU661533B2 (en) | 1992-01-20 | 1995-07-27 | Astrazeneca Ab | Quinazoline derivatives |
WO1994003427A1 (fr) | 1992-08-06 | 1994-02-17 | Warner-Lambert Company | 2-thioindoles (selenoindoles) et disulfures associes (seleniures) inhibant les tyrosine kinases et presentant des proprietes antitumorales |
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EP1975181B1 (fr) | 1992-10-28 | 2011-02-16 | Genentech, Inc. | Utilisation d'antagonistes de facteur de croissance de cellule endothéliale vasculaire |
GB9226855D0 (en) | 1992-12-23 | 1993-02-17 | Erba Carlo Spa | Vinylene-azaindole derivatives and process for their preparation |
GB9624482D0 (en) | 1995-12-18 | 1997-01-15 | Zeneca Phaema S A | Chemical compounds |
JP2000506880A (ja) | 1996-03-15 | 2000-06-06 | ゼネカ・リミテッド | シンノリン誘導体及びその使用 |
UA54427C2 (uk) | 1996-05-01 | 2003-03-17 | Елі Ліллі Енд Компані | Спосіб лікування очних захворювань, які пов'язані з фактором васкулярного ендотеліального росту |
CZ350098A3 (cs) | 1996-05-01 | 1999-11-17 | Eli Lilly And Company | Způsob léčení neoplasie |
GB9707800D0 (en) | 1996-05-06 | 1997-06-04 | Zeneca Ltd | Chemical compounds |
TW513418B (en) | 1996-07-31 | 2002-12-11 | Otsuka Pharma Co Ltd | Thiazole derivatives, their production and use |
ES2327440T3 (es) | 1996-08-23 | 2009-10-29 | Vegenics Limited | Factor recombinante de crecimiento de las celulas endoteliales vasculares-d (vegf-d). |
US6093742A (en) | 1997-06-27 | 2000-07-25 | Vertex Pharmaceuticals, Inc. | Inhibitors of p38 |
JPH11130761A (ja) * | 1997-10-24 | 1999-05-18 | Otsuka Pharmaceut Co Ltd | ベンゾチアゾール誘導体 |
IL135176A0 (en) | 1997-11-10 | 2001-05-20 | Bristol Myers Squibb Co | Benzothiazole derivatives and pharmaceutical compositions containing the same |
JPH11222431A (ja) | 1998-01-30 | 1999-08-17 | Otsuka Pharmaceut Co Ltd | 医薬組成物 |
WO2001007411A1 (fr) | 1999-07-26 | 2001-02-01 | Banyu Pharmaceutical Co., Ltd. | Derives de biaryluree |
-
2001
- 2001-02-06 CA CA002398754A patent/CA2398754A1/fr not_active Abandoned
- 2001-02-06 IL IL15104501A patent/IL151045A0/xx unknown
- 2001-02-06 HU HU0300359A patent/HUP0300359A2/hu unknown
- 2001-02-06 BR BR0108085-7A patent/BR0108085A/pt not_active Application Discontinuation
- 2001-02-06 SK SK1271-2002A patent/SK12712002A3/sk unknown
- 2001-02-06 JP JP2001556858A patent/JP2003521543A/ja not_active Withdrawn
- 2001-02-06 MX MXPA02007632A patent/MXPA02007632A/es unknown
- 2001-02-06 CN CN01807734A patent/CN1422262A/zh active Pending
- 2001-02-06 AU AU2001236698A patent/AU2001236698A1/en not_active Abandoned
- 2001-02-06 WO PCT/US2001/003803 patent/WO2001057008A1/fr not_active Application Discontinuation
- 2001-02-06 KR KR1020027010188A patent/KR20020084116A/ko not_active Application Discontinuation
- 2001-02-06 EP EP01908878A patent/EP1254123A1/fr not_active Withdrawn
- 2001-02-06 PL PL01357099A patent/PL357099A1/xx not_active Application Discontinuation
- 2001-02-06 US US09/777,554 patent/US7091227B2/en not_active Expired - Lifetime
- 2001-02-07 AR ARP010100543A patent/AR030189A1/es unknown
-
2002
- 2002-08-05 ZA ZA200206235A patent/ZA200206235B/en unknown
- 2002-08-06 NO NO20023713A patent/NO20023713L/no not_active Application Discontinuation
- 2002-09-04 BG BG107062A patent/BG107062A/bg unknown
Also Published As
Publication number | Publication date |
---|---|
EP1254123A1 (fr) | 2002-11-06 |
NO20023713D0 (no) | 2002-08-06 |
AR030189A1 (es) | 2003-08-13 |
MXPA02007632A (es) | 2004-08-23 |
WO2001057008A1 (fr) | 2001-08-09 |
BG107062A (bg) | 2003-04-30 |
JP2003521543A (ja) | 2003-07-15 |
AU2001236698A1 (en) | 2001-08-14 |
US7091227B2 (en) | 2006-08-15 |
PL357099A1 (en) | 2004-07-12 |
SK12712002A3 (sk) | 2003-02-04 |
KR20020084116A (ko) | 2002-11-04 |
US20030153568A1 (en) | 2003-08-14 |
CA2398754A1 (fr) | 2001-08-09 |
ZA200206235B (en) | 2004-02-13 |
CN1422262A (zh) | 2003-06-04 |
BR0108085A (pt) | 2003-03-18 |
NO20023713L (no) | 2002-10-04 |
HUP0300359A2 (hu) | 2003-06-28 |
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