FR2945806B1 - Nouveaux derives imidazo[1,2-a]pyridine,procede de preparation,medicaments,compositions pharmaceutiques et utilisation notamment comme inhibiteurs de met - Google Patents

Nouveaux derives imidazo[1,2-a]pyridine,procede de preparation,medicaments,compositions pharmaceutiques et utilisation notamment comme inhibiteurs de met

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Publication number
FR2945806B1
FR2945806B1 FR0902409A FR0902409A FR2945806B1 FR 2945806 B1 FR2945806 B1 FR 2945806B1 FR 0902409 A FR0902409 A FR 0902409A FR 0902409 A FR0902409 A FR 0902409A FR 2945806 B1 FR2945806 B1 FR 2945806B1
Authority
FR
France
Prior art keywords
medicaments
preparation
pharmaceutical compositions
pyridine derivatives
met inhibitors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0902409A
Other languages
English (en)
Other versions
FR2945806A1 (fr
Inventor
Dominique Damour
Conception Nemecek
Patrick Nemecek
Sylvie Wentzler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Sanofi Aventis France
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR0902409A priority Critical patent/FR2945806B1/fr
Application filed by Sanofi Aventis France filed Critical Sanofi Aventis France
Priority to AU2009272517A priority patent/AU2009272517A1/en
Priority to TW098124131A priority patent/TW201006839A/zh
Priority to CN2009801365378A priority patent/CN102159559A/zh
Priority to US13/003,604 priority patent/US20110257171A1/en
Priority to ARP090102711A priority patent/AR072518A1/es
Priority to EA201170223A priority patent/EA201170223A1/ru
Priority to PCT/FR2009/051407 priority patent/WO2010007317A1/fr
Priority to MX2011000675A priority patent/MX2011000675A/es
Priority to JP2011517979A priority patent/JP2011528338A/ja
Priority to BRPI0915924A priority patent/BRPI0915924A2/pt
Priority to CA2730749A priority patent/CA2730749A1/fr
Priority to KR1020117003699A priority patent/KR20110039559A/ko
Priority to EP09737061A priority patent/EP2318382A1/fr
Priority to PE2011000051A priority patent/PE20110572A1/es
Priority to UY0001031997A priority patent/UY31997A/es
Publication of FR2945806A1 publication Critical patent/FR2945806A1/fr
Priority to IL210689A priority patent/IL210689A0/en
Priority to ZA2011/00429A priority patent/ZA201100429B/en
Priority to CO11004611A priority patent/CO6331467A2/es
Priority to CL2011000116A priority patent/CL2011000116A1/es
Priority to MA33619A priority patent/MA32565B1/fr
Application granted granted Critical
Publication of FR2945806B1 publication Critical patent/FR2945806B1/fr
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
FR0902409A 2008-07-18 2009-05-19 Nouveaux derives imidazo[1,2-a]pyridine,procede de preparation,medicaments,compositions pharmaceutiques et utilisation notamment comme inhibiteurs de met Expired - Fee Related FR2945806B1 (fr)

Priority Applications (21)

Application Number Priority Date Filing Date Title
FR0902409A FR2945806B1 (fr) 2009-05-19 2009-05-19 Nouveaux derives imidazo[1,2-a]pyridine,procede de preparation,medicaments,compositions pharmaceutiques et utilisation notamment comme inhibiteurs de met
PE2011000051A PE20110572A1 (es) 2008-07-18 2009-07-16 DERIVADOS DE IMIDAZO[1,2-a]PIRIDINA COMO INHIBIDORES DE MET
EP09737061A EP2318382A1 (fr) 2008-07-18 2009-07-16 NOUVEAUX DERIVES IMIDAZO[1,2-a]PYRIDINE, LEUR PROCEDE DE PREPARATION, LEUR APPLICATION A TITRE DE MEDICAMENTS, COMPOSITIONS PHARMACEUTIQUES ET NOUVELLE UTILISATION NOTAMMENT COMME INHIBITEURS DE MET
US13/003,604 US20110257171A1 (en) 2008-07-18 2009-07-16 Novel imidazo[1,2-a]pyridine derivatives, method for the preparation thereof, use thereof as medicaments, pharmaceutical compositions and novel use in particular as met inhibitors
TW098124131A TW201006839A (en) 2008-07-18 2009-07-16 Novel imidazo[1,2-a]pyridine derivatives, process for the preparation thereof, use thereof as medicaments, pharmaceutical compositions and novel use, in particular as MET inhibitors
EA201170223A EA201170223A1 (ru) 2008-07-18 2009-07-16 НОВЫЕ ПРОИЗВОДНЫЕ ИМИДАЗО[1,2-a]ПИРИДИНА, СПОСОБ ИХ ПОЛУЧЕНИЯ, ИХ ПРИМЕНЕНИЕ В КАЧЕСТВЕ ЛЕКАРСТВЕННЫХ СРЕДСТВ, ФАРМАЦЕВТИЧЕСКИЕ КОМПОЗИЦИИ И НОВОЕ ПРИМЕНЕНИЕ, В ЧАСТНОСТИ, В КАЧЕСТВЕ ИНГИБИТОРОВ МЕТ
PCT/FR2009/051407 WO2010007317A1 (fr) 2008-07-18 2009-07-16 NOUVEAUX DERIVES IMIDAZO[1,2-a]PYRIDINE, LEUR PROCEDE DE PREPARATION, LEUR APPLICATION A TITRE DE MEDICAMENTS, COMPOSITIONS PHARMACEUTIQUES ET NOUVELLE UTILISATION NOTAMMENT COMME INHIBITEURS DE MET
CA2730749A CA2730749A1 (fr) 2008-07-18 2009-07-16 Nouveaux derives imidazo[1,2-a]pyridine, leur procede de preparation, leur application a titre de medicaments, compositions pharmaceutiques et nouvelle utilisation notamment commeinhibiteurs de met
JP2011517979A JP2011528338A (ja) 2008-07-18 2009-07-16 新規イミダゾ［１，２−ａ］ピリジン誘導体、この調製方法、この医薬としての使用、医薬組成物、および新規用途、特にＭＥＴ阻害剤としての用途
BRPI0915924A BRPI0915924A2 (pt) 2008-07-18 2009-07-16 derivados imidazo [1,2-a]piridina, o respectivo processo de preparo, a respectiva aplicação a título de medicamentos, composições farmacêuticas e nova utilização notadamente como inibidores de met
AU2009272517A AU2009272517A1 (en) 2008-07-18 2009-07-16 Novel imidazo[1,2-a]pyridine derivatives, method for the preparation thereof, use thereof as medicaments, pharmaceutical compositions and novel use in particular as MET inhibitors
KR1020117003699A KR20110039559A (ko) 2008-07-18 2009-07-16 신규 이미다조[1,2-ａ]피리딘 유도체, 그의 제조 방법, 의약으로서의 그의 용도, 제약 조성물, 및 특히 ｍｅｔ 억제제로서의 신규 용도
CN2009801365378A CN102159559A (zh) 2008-07-18 2009-07-16 新型咪唑并[1,2-a]吡啶衍生物、其制备方法、其作为药物的用途、其药物组合物和新型用途特别是作为MET抑制剂的新型用途
ARP090102711A AR072518A1 (es) 2008-07-18 2009-07-16 Derivados de imidazo [1,2-a]piridina, su procedimiento de preparacion, composiciones farmaceuticas y su utilizacion particularmente como inhibidores de met."
MX2011000675A MX2011000675A (es) 2008-07-18 2009-07-16 Nuevos derivados de imidazo [1,2-a] piridina, su procedimiento de preparación, su uso como medicamentos, composiciones farmaceuticas y nuevo uso particularmente como inhibidores de met.
UY0001031997A UY31997A (es) 2008-07-18 2009-07-17 Nuevos derivados de imidazo[1,2-a]piridina, y sus nuevos usos como inhibidores de met.
IL210689A IL210689A0 (en) 2008-07-18 2011-01-16 Novel imidazo [1, 2 - a] pyridine derivatives, method for the preparation thereof, use thereof as medicaments, pharmaceutical compositions and novel use in particular as met inhibitors
ZA2011/00429A ZA201100429B (en) 2008-07-18 2011-01-17 Novel imidazo [1,2-a]pyrimidine derivatives,method for the preparation thereof,use thereof as medicaments,pharmaceutical compositions and novel use in particular as met inhibitors
CO11004611A CO6331467A2 (es) 2008-07-18 2011-01-18 Nuevos derivados de imidazo(1,2-a)piridina, su procedimiento de preparacion, su aplicacion como medicamentos, composiciones farmaceuticas y nueva utilizacion particularmente como inhibidores de met
CL2011000116A CL2011000116A1 (es) 2008-07-18 2011-01-18 Compuestos derivados de imidazo[1,2-a]piridina; procedimiento de preparacion; composicion farmaceutica; compuestos intermediarios; y uso en el tratamiento del cancer.
MA33619A MA32565B1 (fr) 2008-07-18 2011-02-15 NOUVEAUX DERIVES IMIDAZO[1,2-a]PYRIDINE, LEUR PROCEDE DE PREPARATION, LEUR APPLICATION A TITRE DE MEDICAMENTS, COMPOSITIONS PHARMACEUTIQUES ET NOUVELLE UTILISATION NOTAMMENT COMME INHIBITEURS DE MET

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0902409A FR2945806B1 (fr) 2009-05-19 2009-05-19 Nouveaux derives imidazo[1,2-a]pyridine,procede de preparation,medicaments,compositions pharmaceutiques et utilisation notamment comme inhibiteurs de met

Publications (2)

Publication Number Publication Date
FR2945806A1 FR2945806A1 (fr) 2010-11-26
FR2945806B1 true FR2945806B1 (fr) 2013-04-05

Family

ID=41338623

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0902409A Expired - Fee Related FR2945806B1 (fr) 2008-07-18 2009-05-19 Nouveaux derives imidazo[1,2-a]pyridine,procede de preparation,medicaments,compositions pharmaceutiques et utilisation notamment comme inhibiteurs de met

Country Status (1)

Country Link
FR (1) FR2945806B1 (fr)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2785157A (en) * 1952-11-05 1957-03-12 Eastman Kodak Co Benzothiazoleazoaniline compounds
GB9919778D0 (en) * 1999-08-21 1999-10-27 Zeneca Ltd Chemical compounds
JP2003521543A (ja) * 2000-02-07 2003-07-15 アボット ゲーエムベーハー ウント カンパニー カーゲー ２−ベンゾチアゾリル尿素誘導体およびそのプロテインキナーゼ阻害剤としての使用
PA8792501A1 (es) * 2007-08-09 2009-04-23 Sanofi Aventis Nuevos derivados de 6-triazolopiridacina-sulfanil benzotiazol y bencimidazol,su procedimiento de preparación,su aplicación como medicamentos,composiciones farmacéuticas y nueva utilización principalmente como inhibidores de met.
ES2393430T3 (es) * 2007-10-17 2012-12-21 Novartis Ag Derivados de imidazo[1,2-A]-piridina útiles como inhibidores de ALK

Also Published As

Publication number Publication date
FR2945806A1 (fr) 2010-11-26

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