EG24928A - Heterocyclic inhibitors of mek and methods of use thereof - Google Patents
Heterocyclic inhibitors of mek and methods of use thereofInfo
- Publication number
- EG24928A EG24928A EGNA2006000472A EG24928A EG 24928 A EG24928 A EG 24928A EG NA2006000472 A EGNA2006000472 A EG NA2006000472A EG 24928 A EG24928 A EG 24928A
- Authority
- EG
- Egypt
- Prior art keywords
- compounds
- methods
- mek
- heterocyclic inhibitors
- mammals
- Prior art date
Links
Classifications
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- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/46—Iso-indoles; Hydrogenated iso-indoles with an oxygen atom in position 1
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- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
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- 2004-11-18 ES ES10008429.2T patent/ES2453367T3/es active Active
- 2004-11-18 EP EP04811721A patent/EP1689406A4/fr not_active Withdrawn
- 2004-11-18 JP JP2006541581A patent/JP4869075B2/ja not_active Expired - Fee Related
- 2004-11-18 PL PL04811727T patent/PL1682138T6/pl unknown
- 2004-11-18 WO PCT/US2004/039060 patent/WO2005051301A2/fr active Application Filing
- 2004-11-18 JP JP2006541580A patent/JP5046649B2/ja not_active Expired - Fee Related
- 2004-11-18 EP EP04811726A patent/EP1689387B1/fr not_active Not-in-force
- 2004-11-18 AU AU2004293436A patent/AU2004293436B2/en not_active Ceased
- 2004-11-18 CA CA002546353A patent/CA2546353A1/fr not_active Abandoned
- 2004-11-18 CN CN2012100805779A patent/CN102633716A/zh active Pending
- 2004-11-18 WO PCT/US2004/039059 patent/WO2005051300A2/fr active Application Filing
- 2004-11-18 CA CA2545660A patent/CA2545660C/fr not_active Expired - Fee Related
- 2004-11-18 US US10/992,470 patent/US7485643B2/en not_active Expired - Fee Related
- 2004-11-18 PT PT04811727T patent/PT1682138E/pt unknown
- 2004-11-18 KR KR1020127009360A patent/KR101264570B1/ko not_active IP Right Cessation
- 2004-11-18 CN CNA2004800406607A patent/CN1905873A/zh active Pending
- 2004-11-18 WO PCT/US2004/039053 patent/WO2005051906A2/fr active Application Filing
- 2004-11-18 RU RU2006120948/04A patent/RU2351593C2/ru not_active IP Right Cessation
- 2004-11-18 EP EP10008429.2A patent/EP2251327B1/fr active Active
- 2004-11-18 BR BRPI0416692-2A patent/BRPI0416692A/pt not_active IP Right Cessation
- 2004-11-18 PL PL04811728T patent/PL1689233T3/pl unknown
- 2004-11-18 EP EP04811728A patent/EP1689233B1/fr not_active Not-in-force
- 2004-11-18 PT PT04811726T patent/PT1689387E/pt unknown
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