DE852949T1 - Verwendung von Alpha-Aminosäuren zur Förderung des desmosomalen Abbaues oder der Abschuppung der Hornschicht - Google Patents
Verwendung von Alpha-Aminosäuren zur Förderung des desmosomalen Abbaues oder der Abschuppung der HornschichtInfo
- Publication number
- DE852949T1 DE852949T1 DE0852949T DE98105789T DE852949T1 DE 852949 T1 DE852949 T1 DE 852949T1 DE 0852949 T DE0852949 T DE 0852949T DE 98105789 T DE98105789 T DE 98105789T DE 852949 T1 DE852949 T1 DE 852949T1
- Authority
- DE
- Germany
- Prior art keywords
- group
- lower alkyl
- amino acid
- use according
- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 235000008206 alpha-amino acids Nutrition 0.000 title claims 4
- 206010040844 Skin exfoliation Diseases 0.000 title claims 3
- 230000015556 catabolic process Effects 0.000 title claims 3
- 238000006731 degradation reaction Methods 0.000 title claims 3
- 230000035618 desquamation Effects 0.000 title claims 3
- 150000001371 alpha-amino acids Chemical class 0.000 title claims 2
- 125000000217 alkyl group Chemical group 0.000 claims 5
- 150000001370 alpha-amino acid derivatives Chemical class 0.000 claims 4
- 210000003491 skin Anatomy 0.000 claims 4
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 3
- -1 2-hydroxypropane-1,3-diyl Chemical group 0.000 claims 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 2
- 210000000434 stratum corneum Anatomy 0.000 claims 2
- MTCFGRXMJLQNBG-REOHCLBHSA-N (2S)-2-Amino-3-hydroxypropansäure Chemical compound OC[C@H](N)C(O)=O MTCFGRXMJLQNBG-REOHCLBHSA-N 0.000 claims 1
- 239000004475 Arginine Substances 0.000 claims 1
- DCXYFEDJOCDNAF-UHFFFAOYSA-N Asparagine Natural products OC(=O)C(N)CC(N)=O DCXYFEDJOCDNAF-UHFFFAOYSA-N 0.000 claims 1
- XUJNEKJLAYXESH-REOHCLBHSA-N L-Cysteine Chemical compound SC[C@H](N)C(O)=O XUJNEKJLAYXESH-REOHCLBHSA-N 0.000 claims 1
- ONIBWKKTOPOVIA-BYPYZUCNSA-N L-Proline Chemical compound OC(=O)[C@@H]1CCCN1 ONIBWKKTOPOVIA-BYPYZUCNSA-N 0.000 claims 1
- QNAYBMKLOCPYGJ-REOHCLBHSA-N L-alanine Chemical compound C[C@H](N)C(O)=O QNAYBMKLOCPYGJ-REOHCLBHSA-N 0.000 claims 1
- ODKSFYDXXFIFQN-BYPYZUCNSA-P L-argininium(2+) Chemical compound NC(=[NH2+])NCCC[C@H]([NH3+])C(O)=O ODKSFYDXXFIFQN-BYPYZUCNSA-P 0.000 claims 1
- DCXYFEDJOCDNAF-REOHCLBHSA-N L-asparagine Chemical compound OC(=O)[C@@H](N)CC(N)=O DCXYFEDJOCDNAF-REOHCLBHSA-N 0.000 claims 1
- ZDXPYRJPNDTMRX-VKHMYHEASA-N L-glutamine Chemical compound OC(=O)[C@@H](N)CCC(N)=O ZDXPYRJPNDTMRX-VKHMYHEASA-N 0.000 claims 1
- HNDVDQJCIGZPNO-YFKPBYRVSA-N L-histidine Chemical compound OC(=O)[C@@H](N)CC1=CN=CN1 HNDVDQJCIGZPNO-YFKPBYRVSA-N 0.000 claims 1
- AGPKZVBTJJNPAG-WHFBIAKZSA-N L-isoleucine Chemical compound CC[C@H](C)[C@H](N)C(O)=O AGPKZVBTJJNPAG-WHFBIAKZSA-N 0.000 claims 1
- ROHFNLRQFUQHCH-YFKPBYRVSA-N L-leucine Chemical compound CC(C)C[C@H](N)C(O)=O ROHFNLRQFUQHCH-YFKPBYRVSA-N 0.000 claims 1
- KDXKERNSBIXSRK-YFKPBYRVSA-N L-lysine Chemical compound NCCCC[C@H](N)C(O)=O KDXKERNSBIXSRK-YFKPBYRVSA-N 0.000 claims 1
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 claims 1
- COLNVLDHVKWLRT-QMMMGPOBSA-N L-phenylalanine Chemical compound OC(=O)[C@@H](N)CC1=CC=CC=C1 COLNVLDHVKWLRT-QMMMGPOBSA-N 0.000 claims 1
- AYFVYJQAPQTCCC-GBXIJSLDSA-N L-threonine Chemical compound C[C@@H](O)[C@H](N)C(O)=O AYFVYJQAPQTCCC-GBXIJSLDSA-N 0.000 claims 1
- QIVBCDIJIAJPQS-VIFPVBQESA-N L-tryptophane Chemical compound C1=CC=C2C(C[C@H](N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-VIFPVBQESA-N 0.000 claims 1
- OUYCCCASQSFEME-QMMMGPOBSA-N L-tyrosine Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-QMMMGPOBSA-N 0.000 claims 1
- KZSNJWFQEVHDMF-BYPYZUCNSA-N L-valine Chemical compound CC(C)[C@H](N)C(O)=O KZSNJWFQEVHDMF-BYPYZUCNSA-N 0.000 claims 1
- ROHFNLRQFUQHCH-UHFFFAOYSA-N Leucine Natural products CC(C)CC(N)C(O)=O ROHFNLRQFUQHCH-UHFFFAOYSA-N 0.000 claims 1
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 claims 1
- 239000004472 Lysine Substances 0.000 claims 1
- ONIBWKKTOPOVIA-UHFFFAOYSA-N Proline Natural products OC(=O)C1CCCN1 ONIBWKKTOPOVIA-UHFFFAOYSA-N 0.000 claims 1
- MTCFGRXMJLQNBG-UHFFFAOYSA-N Serine Natural products OCC(N)C(O)=O MTCFGRXMJLQNBG-UHFFFAOYSA-N 0.000 claims 1
- AYFVYJQAPQTCCC-UHFFFAOYSA-N Threonine Natural products CC(O)C(N)C(O)=O AYFVYJQAPQTCCC-UHFFFAOYSA-N 0.000 claims 1
- 239000004473 Threonine Substances 0.000 claims 1
- QIVBCDIJIAJPQS-UHFFFAOYSA-N Tryptophan Natural products C1=CC=C2C(CC(N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-UHFFFAOYSA-N 0.000 claims 1
- KZSNJWFQEVHDMF-UHFFFAOYSA-N Valine Natural products CC(C)C(N)C(O)=O KZSNJWFQEVHDMF-UHFFFAOYSA-N 0.000 claims 1
- 239000004480 active ingredient Substances 0.000 claims 1
- 125000002252 acyl group Chemical group 0.000 claims 1
- 235000004279 alanine Nutrition 0.000 claims 1
- 229960003767 alanine Drugs 0.000 claims 1
- 125000003368 amide group Chemical group 0.000 claims 1
- 125000003277 amino group Chemical group 0.000 claims 1
- 235000009697 arginine Nutrition 0.000 claims 1
- 229960003121 arginine Drugs 0.000 claims 1
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 claims 1
- 235000009582 asparagine Nutrition 0.000 claims 1
- 229960001230 asparagine Drugs 0.000 claims 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 claims 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 1
- 125000003262 carboxylic acid ester group Chemical class [H]C([H])([*:2])OC(=O)C([H])([H])[*:1] 0.000 claims 1
- 239000002537 cosmetic Substances 0.000 claims 1
- 235000018417 cysteine Nutrition 0.000 claims 1
- 229960002433 cysteine Drugs 0.000 claims 1
- XUJNEKJLAYXESH-UHFFFAOYSA-N cysteine Natural products SCC(N)C(O)=O XUJNEKJLAYXESH-UHFFFAOYSA-N 0.000 claims 1
- 230000002708 enhancing effect Effects 0.000 claims 1
- ZDXPYRJPNDTMRX-UHFFFAOYSA-N glutamine Natural products OC(=O)C(N)CCC(N)=O ZDXPYRJPNDTMRX-UHFFFAOYSA-N 0.000 claims 1
- 229960002743 glutamine Drugs 0.000 claims 1
- 125000000623 heterocyclic group Chemical group 0.000 claims 1
- 235000014304 histidine Nutrition 0.000 claims 1
- 229960002885 histidine Drugs 0.000 claims 1
- HNDVDQJCIGZPNO-UHFFFAOYSA-N histidine Natural products OC(=O)C(N)CC1=CN=CN1 HNDVDQJCIGZPNO-UHFFFAOYSA-N 0.000 claims 1
- 235000014705 isoleucine Nutrition 0.000 claims 1
- 229960000310 isoleucine Drugs 0.000 claims 1
- AGPKZVBTJJNPAG-UHFFFAOYSA-N isoleucine Natural products CCC(C)C(N)C(O)=O AGPKZVBTJJNPAG-UHFFFAOYSA-N 0.000 claims 1
- 235000005772 leucine Nutrition 0.000 claims 1
- 229960003136 leucine Drugs 0.000 claims 1
- 235000018977 lysine Nutrition 0.000 claims 1
- 229960003646 lysine Drugs 0.000 claims 1
- 235000006109 methionine Nutrition 0.000 claims 1
- 229930182817 methionine Natural products 0.000 claims 1
- 229960004452 methionine Drugs 0.000 claims 1
- 229910052757 nitrogen Inorganic materials 0.000 claims 1
- 125000004433 nitrogen atom Chemical group N* 0.000 claims 1
- 235000008729 phenylalanine Nutrition 0.000 claims 1
- 229960005190 phenylalanine Drugs 0.000 claims 1
- COLNVLDHVKWLRT-UHFFFAOYSA-N phenylalanine Natural products OC(=O)C(N)CC1=CC=CC=C1 COLNVLDHVKWLRT-UHFFFAOYSA-N 0.000 claims 1
- 229960002429 proline Drugs 0.000 claims 1
- 150000003856 quaternary ammonium compounds Chemical class 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 235000004400 serine Nutrition 0.000 claims 1
- 229960001153 serine Drugs 0.000 claims 1
- 125000001424 substituent group Chemical group 0.000 claims 1
- 125000003396 thiol group Chemical group [H]S* 0.000 claims 1
- 235000008521 threonine Nutrition 0.000 claims 1
- 229960002898 threonine Drugs 0.000 claims 1
- 238000011200 topical administration Methods 0.000 claims 1
- 125000003258 trimethylene group Chemical group [H]C([H])([*:2])C([H])([H])C([H])([H])[*:1] 0.000 claims 1
- 229960004799 tryptophan Drugs 0.000 claims 1
- 235000002374 tyrosine Nutrition 0.000 claims 1
- 229960004441 tyrosine Drugs 0.000 claims 1
- OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 claims 1
- 235000014393 valine Nutrition 0.000 claims 1
- 229960004295 valine Drugs 0.000 claims 1
- 239000004474 valine Substances 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4172—Imidazole-alkanecarboxylic acids, e.g. histidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/401—Proline; Derivatives thereof, e.g. captopril
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Dermatology (AREA)
- Birds (AREA)
- Cosmetics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Claims (6)
1. Verwendung eines kosmetischen oder dermatologischen topisch zu verabreichenden Präparats, das als Wirkstoff
mindestens ein a-Aminosäurederivat der folgenden Formel (I) enthält, das in Form eines Salzes eines Carbonsäureesters
oder einer quaternären Ammoniumverbindung, wenn sowohl R2 als auch R3 Niedrigalkylreste sind, sein kann
zur Verstärkung der Desquamation des Stratum Corneum oder des desmosomalen Abbaus der Haut und/oder zur Verhütung
und Abnahme der Glanzlosigkeit der Haut:
R2 R1
N-CH-COOH (D
R3
worin R1 ein Wasserstoffatom oder ein unsubstituierter
oder substituierter Niedrigalkylrest ist und der Substituent in dem substituierten Niedrigalkylrest eine Hydroxylgruppe,
eine Mercaptogruppe, die gegebenenfalls durch
eine Niedrigalkylgruppe substituiert sein kann, eine Aminogruppe, die gegebenenfalls durch eine Niedrigalkyl-
- &khgr;-
gruppe, eine Niedrigacylgruppe, eine Amidogruppe substituiert
sein kann, oder eine N-mono- oder N,N1-Di(niedrigalkyl)araidinogruppe,
eine Phenylgruppe, die gegebenenfalls durch eine Hydroxylgruppe substituiert sein kann, ein
fünfgliedriger heterocyclischer Ring, der ein oder zwei
Stickstoffatome im Ring besitzt und der gegebenenfalls mit einem Benzolring fusioniert sein kann, oder eine Carbamoylgruppe
ist; und R1 und R2 unabhängig voneinander ein Wasserstoffatom, einen Niedrigalkylrest oder einen niedrigen,
mittleren oder höheren Acylrest bedeuten; oder
jeder der Reste R2 und R3 mit R1 unter Bildung einer Propan-1,3-diyl-, 2-Hydroxypropan-l,3-diyl- oder 1-Hydroxypropan-1,3-diyl-Gruppe kombiniert ist.
jeder der Reste R2 und R3 mit R1 unter Bildung einer Propan-1,3-diyl-, 2-Hydroxypropan-l,3-diyl- oder 1-Hydroxypropan-1,3-diyl-Gruppe kombiniert ist.
2. Verwendung nach Anspruch 1, wobei das a-Aminosäurederivat aus der Gruppe, bestehend aus natürlich vorkommenden
&agr;-Aminosäuren und Racematen davon, ausgewählt ist.
3. Verwendung nach Anspruch 1 oder 2, wobei R2 und R3 in
der Formel (I) jeweils unabhängig voneinander ein Wasserstoff atom, einen Niedrigalkylrest oder einen Niedrigacylrest
bedeuten.
4. Verwendung nach Anspruch 1 oder 2, wobei das a-Aminosäurederivat
eine &agr;-Aminosäure, ausgewählt aus der Gruppe bestehend aus Alanin, Valin, Leucin, Isoleucin, Serin,
Threonin, Cystein, Methionin, Lysin, Arginin, Phenylalanin, Tyrosin, Histidin, Tryptophan, Aspargin, Glutamin
und Prolin, oder ein Derivat der &agr;-Aminosäure ist.
5. Verwendung nach einem der Ansprüche 1 bis 4, wobei das Präparat zur Verstärkung der Desquamation des Stratum
Corneum der Haut verwendet wird.
6. Verwendung nach einem der Ansprüche 1 bis 4, wobei das Präparat zur Verstärkung des desmosomalen Abbaus der
Haut verwendet wird.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP9438997 | 1997-03-31 | ||
JP24482797 | 1997-08-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
DE852949T1 true DE852949T1 (de) | 1998-11-19 |
Family
ID=26435659
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE0852949T Pending DE852949T1 (de) | 1997-03-31 | 1998-03-30 | Verwendung von Alpha-Aminosäuren zur Förderung des desmosomalen Abbaues oder der Abschuppung der Hornschicht |
Country Status (5)
Country | Link |
---|---|
US (1) | US20020041889A1 (de) |
EP (1) | EP0852949A3 (de) |
KR (1) | KR19980080965A (de) |
DE (1) | DE852949T1 (de) |
TW (1) | TW508247B (de) |
Families Citing this family (119)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7396526B1 (en) | 1998-11-12 | 2008-07-08 | Johnson & Johnson Consumer Companies, Inc. | Skin care composition |
KR20000044978A (ko) * | 1998-12-30 | 2000-07-15 | 성재갑 | 각질 박리 촉진용 조성물 |
US6242491B1 (en) | 1999-06-25 | 2001-06-05 | Rima Kaddurah-Daouk | Use of creatine or creatine compounds for skin preservation |
DE10032964B4 (de) * | 2000-07-06 | 2017-10-12 | Beiersdorf Ag | Verwendung von Kreatin in kosmetischen oder dermatologischen Zubereitungen |
US20020071818A1 (en) * | 2000-10-02 | 2002-06-13 | Cole Curtis A. | Skin cleanser containing anti-aging active |
FR2816837A1 (fr) * | 2000-11-17 | 2002-05-24 | Oreal | Utilisation d'au moins un derive amino sulfonique dans une composition destinee a favoriser la desquamation de la peau |
FR2816838B1 (fr) * | 2000-11-17 | 2004-12-03 | Oreal | Utilisation de derives de l'acide 2-oxothiazolidine- 4-carboxylique comme agents prodesquamants |
DE10148966A1 (de) * | 2001-10-04 | 2003-04-10 | Beiersdorf Ag | Betainhaltige Kosmetika |
FR2834635A1 (fr) * | 2002-01-17 | 2003-07-18 | Oreal | Utilisation de l'acide methyl glycinediacetique ou de ses derives comme desquamant |
FR2831445A1 (fr) * | 2002-02-14 | 2003-05-02 | Oreal | Composition comprenant au moins un pro-desquamant et au moins un compose activateur de la melanogenese |
EP1459736A1 (de) * | 2003-03-14 | 2004-09-22 | The Procter & Gamble Company | Hautpflegezusammensetzung zur Verbesserung der Barrierefunktion der Haut |
FR2864445B1 (fr) * | 2003-12-30 | 2006-04-28 | Jean Noel Thorel | Utilisation topique d'une base nutritive complexe |
US20050232894A1 (en) * | 2004-04-20 | 2005-10-20 | Weiner Gregory M | Antimicrobial skin treatment composition and methods for producing and using an antimicrobial skin treatment composition |
FR2871688B1 (fr) | 2004-06-16 | 2008-05-16 | Oreal | Procede pour favoriser la penetration d'un actif et composition permettant sa mise en oeuvre |
FR2874321B1 (fr) | 2004-08-17 | 2010-11-26 | Oreal | Composition topique comprenant des particules poreuses chargees et un compose absorbant le sebum |
FR2875134B1 (fr) | 2004-09-16 | 2007-08-24 | Oreal | Utilisation cosmetique d'une composition renfermant un derive ascorbique et des particules de polyamide |
US7300649B2 (en) | 2005-02-11 | 2007-11-27 | Genepharm, Inc. | Cosmetic and cosmeceutical compositions for restoration of skin barrier function |
FR2883168B1 (fr) | 2005-03-18 | 2008-01-11 | Oreal | Compositions cosmetiques de soin, renforcement et/ou reparation des substrats keratiniques comprenant des polypeptides kap |
JP4865251B2 (ja) * | 2005-05-09 | 2012-02-01 | 株式会社 資生堂 | 不全角化抑制剤、毛穴縮小剤及び皮膚外用組成物 |
FR2889808B1 (fr) | 2005-08-17 | 2011-07-22 | Oreal | Utilisation de l'acide 8-hexadecene-1,16-dicarboxylique comme agent de soin destine a favoriser la cohesion de la couche cornee |
FR2902999B1 (fr) | 2006-07-03 | 2012-09-28 | Oreal | Utilisation de derives c-glycoside a titre d'actif prodesquamant |
FR2909552B1 (fr) | 2006-12-12 | 2009-11-20 | Oreal | Utilisation cosmetique de l'acide anisique pour favoriser la desquamation |
FR2912917B1 (fr) | 2007-02-26 | 2012-05-18 | Oreal | Milieu conditionne et ses utilisations |
US20080227747A1 (en) * | 2007-03-15 | 2008-09-18 | Tabbiner Philip | Composition and methods for treating or preventing degenerative joint and cardiovascular conditions |
FR2914189A1 (fr) | 2007-03-26 | 2008-10-03 | Oreal | Utilisation d'une fraction lipopolysaccharidique de vitreoscilla filiformis comme agent stimulant la synthese de peptides antimicrobiens de la peau. |
FR2918269B1 (fr) | 2007-07-06 | 2016-11-25 | Oreal | Composition de protection solaire contenant l'association d'un polymere semi-cristallin et de particules de latex creuses. |
FR2918561B1 (fr) | 2007-07-09 | 2009-10-09 | Oreal | Utilisation pour la coloration de la peau de l'acide dehydroascorbique ou des derives polymeres ; procedes de soin et/ou de maquillage. |
FR2918563B1 (fr) | 2007-07-12 | 2009-12-04 | Oreal | Composition photoprotectrice fluide aqueuse a base d'un polymere polyamide a terminaison amide tertiaire. |
FR2918886B1 (fr) | 2007-07-17 | 2010-01-08 | Oreal | Utilisation d'au moins un extrait bacterien cultive sur eau thermale pour le traitement des peaux, muqueuses et cuirs chevelus sensibles |
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WO2024028513A1 (en) | 2022-08-05 | 2024-02-08 | Symrise Ag | Odor and colorant stabilized compositions |
FR3142901A1 (fr) | 2022-12-09 | 2024-06-14 | L'oreal | Compositions cosmétiques avec meilleure résistance à l’usure et au transfert |
WO2024049923A1 (en) | 2022-08-31 | 2024-03-07 | L'oreal | Compositions and methods for skin |
WO2024049867A1 (en) | 2022-08-31 | 2024-03-07 | L'oreal | Cosmetic compositions with improved wear and transfer resistance |
FR3143355A1 (fr) | 2022-12-14 | 2024-06-21 | L'oreal | Compositions et procédés de prévention et/ou de traitement des cicatrices |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6130509A (ja) * | 1984-07-23 | 1986-02-12 | Shiseido Co Ltd | 皮膚外用剤 |
JPS61227515A (ja) * | 1985-04-01 | 1986-10-09 | Shiseido Co Ltd | 皮膚外用剤 |
JPS63230615A (ja) * | 1987-03-20 | 1988-09-27 | Shiseido Co Ltd | 化粧料 |
FR2627385B3 (fr) * | 1988-02-23 | 1991-08-23 | Serobiologiques Lab Sa | Composition notamment utile comme matiere de base pour la preparation de compositions pharmaceutiques, notamment dermatologiques et/ou cosmetiques |
JPH06145037A (ja) * | 1992-05-28 | 1994-05-24 | Shiseido Co Ltd | 皮膚外用剤 |
ATE215810T1 (de) * | 1994-07-01 | 2002-04-15 | Procter & Gamble | Abschuppungs-zusammensetzung |
FR2738484B1 (fr) * | 1995-09-07 | 1997-10-03 | Oreal | Utilisation de l'acide cysteique ou homocysteique pour favoriser la desquamation de la peau ou stimuler le renouvellement epidermique |
-
1998
- 1998-03-30 EP EP98105789A patent/EP0852949A3/de not_active Withdrawn
- 1998-03-30 DE DE0852949T patent/DE852949T1/de active Pending
- 1998-03-30 TW TW087104724A patent/TW508247B/zh not_active IP Right Cessation
- 1998-03-31 US US09/052,023 patent/US20020041889A1/en not_active Abandoned
- 1998-03-31 KR KR1019980011374A patent/KR19980080965A/ko not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
TW508247B (en) | 2002-11-01 |
US20020041889A1 (en) | 2002-04-11 |
EP0852949A3 (de) | 1999-08-04 |
KR19980080965A (ko) | 1998-11-25 |
EP0852949A2 (de) | 1998-07-15 |
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