DE60331479D1 - Pyrimidin-derivate zur behandlung von anormalem zellwachstum - Google Patents

Pyrimidin-derivate zur behandlung von anormalem zellwachstum

Info

Publication number
DE60331479D1
DE60331479D1 DE60331479T DE60331479T DE60331479D1 DE 60331479 D1 DE60331479 D1 DE 60331479D1 DE 60331479 T DE60331479 T DE 60331479T DE 60331479 T DE60331479 T DE 60331479T DE 60331479 D1 DE60331479 D1 DE 60331479D1
Authority
DE
Germany
Prior art keywords
cell growth
abnormal cell
pyrimidine derivatives
treating abnormal
treating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60331479T
Other languages
English (en)
Inventor
John Charles Kath
Michael Joseph Luzzio
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Products Inc
Original Assignee
Pfizer Products Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc filed Critical Pfizer Products Inc
Application granted granted Critical
Publication of DE60331479D1 publication Critical patent/DE60331479D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
DE60331479T 2002-12-20 2003-12-08 Pyrimidin-derivate zur behandlung von anormalem zellwachstum Expired - Lifetime DE60331479D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US43567002P 2002-12-20 2002-12-20
US50074203P 2003-09-05 2003-09-05
PCT/IB2003/005883 WO2004056807A1 (en) 2002-12-20 2003-12-08 Pyrimidine derivatives for the treatment of abnormal cell growth

Publications (1)

Publication Number Publication Date
DE60331479D1 true DE60331479D1 (de) 2010-04-08

Family

ID=32685406

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60331479T Expired - Lifetime DE60331479D1 (de) 2002-12-20 2003-12-08 Pyrimidin-derivate zur behandlung von anormalem zellwachstum

Country Status (31)

Country Link
US (4) US7109335B2 (de)
EP (1) EP1625121B1 (de)
AP (1) AP2385A (de)
AR (1) AR043682A1 (de)
AT (1) ATE458731T1 (de)
AU (2) AU2003285614B2 (de)
CA (1) CA2529611C (de)
CR (2) CR8266A (de)
CY (1) CY1110069T1 (de)
DE (1) DE60331479D1 (de)
DK (1) DK1625121T3 (de)
DO (1) DOP2003000793A (de)
EA (1) EA013248B1 (de)
EC (1) ECSP066406A (de)
ES (1) ES2338545T3 (de)
GE (1) GEP20084357B (de)
IL (1) IL172047A (de)
MX (1) MXPA06002608A (de)
MY (1) MY142109A (de)
NL (1) NL1025067C2 (de)
NZ (1) NZ543719A (de)
OA (1) OA13309A (de)
PA (1) PA8593001A1 (de)
PE (1) PE20041016A1 (de)
PL (1) PL379330A1 (de)
PT (1) PT1625121E (de)
RS (1) RS20060097A (de)
SI (1) SI1625121T1 (de)
TN (1) TNSN06074A1 (de)
TW (1) TWI283673B (de)
WO (1) WO2004056807A1 (de)

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BRPI0510980A (pt) * 2004-05-14 2007-11-27 Pfizer Prod Inc derivados de pirimidina para o tratamento do crescimento anormal de células
BRPI0511132A (pt) * 2004-05-14 2007-11-27 Pfizer Prod Inc derivados de pirimidina e composição farmacêutica compreendendo os mesmos
WO2005111016A1 (en) * 2004-05-14 2005-11-24 Pfizer Products Inc. Pyrimidine derivatives for the treatment of abnormal cell growth

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OA13309A (en) 2007-04-13
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US7674796B2 (en) 2010-03-09
AU2009208172B2 (en) 2011-06-16
US7741336B2 (en) 2010-06-22
EP1625121A1 (de) 2006-02-15
AR043682A1 (es) 2005-08-10
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CA2529611A1 (en) 2004-07-08
CA2529611C (en) 2009-12-15
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AU2003285614A1 (en) 2004-07-14
US20050009853A1 (en) 2005-01-13
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