DE602004022035D1 - Verwendung von pthalide derivativen zur behandlung - Google Patents

Verwendung von pthalide derivativen zur behandlung

Info

Publication number
DE602004022035D1
DE602004022035D1 DE602004022035T DE602004022035T DE602004022035D1 DE 602004022035 D1 DE602004022035 D1 DE 602004022035D1 DE 602004022035 T DE602004022035 T DE 602004022035T DE 602004022035 T DE602004022035 T DE 602004022035T DE 602004022035 D1 DE602004022035 D1 DE 602004022035D1
Authority
DE
Germany
Prior art keywords
pthalide
derivatives
treatment
pthalide derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE602004022035T
Other languages
English (en)
Inventor
Ying Wang
Saizieu Antoine De
Goede Schueler
Orazio Daniel D
Daniel Raederstorff
Swen Wolfram
Peter Weber
Sandra Teixeira
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DSM IP Assets BV
Original Assignee
DSM IP Assets BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by DSM IP Assets BV filed Critical DSM IP Assets BV
Publication of DE602004022035D1 publication Critical patent/DE602004022035D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
DE602004022035T 2003-05-14 2004-05-05 Verwendung von pthalide derivativen zur behandlung Expired - Lifetime DE602004022035D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP03010804 2003-05-14
PCT/EP2004/004768 WO2004100945A1 (en) 2003-05-14 2004-05-05 Use of phthalide derivatives for the treatment and prevention of diabetes mellitus

Publications (1)

Publication Number Publication Date
DE602004022035D1 true DE602004022035D1 (de) 2009-08-27

Family

ID=33442726

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602004022035T Expired - Lifetime DE602004022035D1 (de) 2003-05-14 2004-05-05 Verwendung von pthalide derivativen zur behandlung

Country Status (8)

Country Link
US (2) US20070082947A1 (de)
EP (1) EP1622605B1 (de)
JP (2) JP4804353B2 (de)
KR (1) KR101207652B1 (de)
CN (1) CN100562314C (de)
DE (1) DE602004022035D1 (de)
ES (1) ES2327639T3 (de)
WO (1) WO2004100945A1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1605336A (zh) * 2003-10-10 2005-04-13 中国医学科学院药物研究所 左旋丁基苯酞在制备预防和治疗脑梗塞的药物中的应用
ES2375302T3 (es) * 2005-05-24 2012-02-28 Dsm Ip Assets B.V. Derivados de ligustilida para el tratamiento de trastornos inflamatorios.
KR20090078777A (ko) * 2006-08-11 2009-07-20 디에스엠 아이피 어셋츠 비.브이. 중추 신경계 질환의 치료를 위한 리구스틸라이드 유도체
JP2009256208A (ja) * 2006-08-17 2009-11-05 Dainippon Sumitomo Pharma Co Ltd フタリド誘導体またはその薬学的に許容される塩
CN101302208B (zh) * 2008-03-04 2012-12-26 中央民族大学 抑制谷胱甘肽s-转移酶活性的化合物、其制备方法、其应用
BR112012020058A2 (pt) * 2010-02-10 2016-11-01 Mapi Pharma Ltd preparação de benzofuranos e uso dos mesmos como intermediários sintéticos.
JP5581120B2 (ja) * 2010-06-07 2014-08-27 花王株式会社 電位依存性カチオンチャネル抑制剤
CN102267977B (zh) * 2011-05-06 2014-09-10 中国药科大学 一种3-取代苯并[c]呋喃酮的硫代、硒代同系物、其制备方法及医药用途
TWI484033B (zh) * 2013-01-25 2015-05-11 Univ China Medical 培養幹細胞之方法及套組
CN104546827B (zh) * 2013-10-09 2019-12-27 石药集团恩必普药业有限公司 丁基苯酞或其衍生物在制备治疗或预防糖尿病的药物中的应用
CN104546828B (zh) * 2013-10-09 2017-11-14 石药集团恩必普药业有限公司 丁基苯酞或其衍生物在制备治疗或预防糖尿病并发症的药物中的应用
TWI547280B (zh) * 2014-04-24 2016-09-01 長弘生物科技股份有限公司 穩定醫藥組合物
TWI625391B (zh) * 2014-09-17 2018-06-01 國璽幹細胞應用技術股份有限公司 藁本內酯之應用
WO2017102790A1 (en) * 2015-12-18 2017-06-22 Dsm Ip Assets B.V. Biaromatic vitamin d analogs
CN107446882B (zh) 2016-05-20 2021-06-22 东华大学 亚丁基苯酞的应用
ES2933150B2 (es) * 2021-07-29 2023-08-03 Univ Cadiz Uso de 3-arilftalidas y sus derivados como agentes antiinflamatorios

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4753935A (en) * 1987-01-30 1988-06-28 Syntex (U.S.A.) Inc. Morpholinoethylesters of mycophenolic acid and pharmaceutical compositions
JPH01207233A (ja) * 1988-02-12 1989-08-21 Tsumura & Co 抗動脈硬化症剤
JPH01254671A (ja) * 1988-04-05 1989-10-11 Tsumura & Co 新規リグスチリド類
JPH05247022A (ja) * 1990-07-10 1993-09-24 Tsumura & Co 新規フタリドおよびフタリドを有効成分とする脳機能改善剤
JPH04173740A (ja) * 1990-11-06 1992-06-22 Kobe Steel Ltd フタライド類含有植物・生薬エキス抽出法
WO1995000157A1 (en) * 1993-06-25 1995-01-05 Mobius Consultancy Pty. Ltd. Therapeutic agent
CN1069036C (zh) 1995-07-21 2001-08-01 崔景岳 灵芝仙饮
JP4719372B2 (ja) * 2000-06-21 2011-07-06 花王株式会社 Ｐｐａｒ依存的遺伝子転写活性化剤
CN1182127C (zh) * 2000-06-28 2004-12-29 中国医学科学院药物研究所 新的取代的2-苯并[c]呋喃酮化合物,其制备方法以及包含它们的药物组合物
ITRM20010136A1 (it) * 2001-03-16 2002-09-16 Sigma Tau Ind Farmaceuti Composti utili per il trattamento di patologie che rispondono all'attivazione del recettore ppar-gamma.
DE10131057A1 (de) * 2001-06-29 2003-01-23 Shandong Luya Pharmaceutical C Weiche, Angelikaöl enthaltende Gelkapsel und deren Herstellung
JP2003171303A (ja) * 2001-09-17 2003-06-20 Suzuka Univ Of Medical Science 特定植物含有組成物と該組成物を有効成分とする医薬品と保健用食品
US20030165580A1 (en) * 2002-03-04 2003-09-04 Xinxian Zhao Safe pharmaceutical composition for treatment and prevention of gynecological disease
KR100504408B1 (ko) * 2002-10-29 2005-07-27 주식회사 코리아나화장품 생큐노라이드 ａ를 포함하는 피부 미백용 화장료 조성물

Also Published As

Publication number Publication date
JP2012006923A (ja) 2012-01-12
CN100562314C (zh) 2009-11-25
US8242168B2 (en) 2012-08-14
KR101207652B1 (ko) 2012-12-03
US20070082947A1 (en) 2007-04-12
WO2004100945A1 (en) 2004-11-25
JP2006528666A (ja) 2006-12-21
US20090192218A1 (en) 2009-07-30
EP1622605A1 (de) 2006-02-08
CN1787815A (zh) 2006-06-14
JP4804353B2 (ja) 2011-11-02
EP1622605B1 (de) 2009-07-15
KR20060011865A (ko) 2006-02-03
JP5249388B2 (ja) 2013-07-31
ES2327639T3 (es) 2009-11-02

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