DE60224039D1 - Stickstoffhaltige, bicyclische heterocyclen zur verwendung als antibakterielle mittel - Google Patents
Stickstoffhaltige, bicyclische heterocyclen zur verwendung als antibakterielle mittelInfo
- Publication number
- DE60224039D1 DE60224039D1 DE60224039T DE60224039T DE60224039D1 DE 60224039 D1 DE60224039 D1 DE 60224039D1 DE 60224039 T DE60224039 T DE 60224039T DE 60224039 T DE60224039 T DE 60224039T DE 60224039 D1 DE60224039 D1 DE 60224039D1
- Authority
- DE
- Germany
- Prior art keywords
- nitrogenic
- antibacterial agents
- bicyclic heterocycles
- heterocycles
- bicyclic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0112834.7A GB0112834D0 (en) | 2001-05-25 | 2001-05-25 | Medicaments |
GB0112834 | 2001-05-25 | ||
PCT/EP2002/005708 WO2003087098A1 (en) | 2001-05-25 | 2002-05-24 | Nitrogen-containing bicyclic heterocycles for use as antibacterials |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60224039D1 true DE60224039D1 (de) | 2008-01-24 |
DE60224039T2 DE60224039T2 (de) | 2008-11-27 |
Family
ID=9915342
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60224039T Expired - Lifetime DE60224039T2 (de) | 2001-05-25 | 2002-05-24 | Stickstoffhaltige, bicyclische heterocyclen zur verwendung als antibakterielle mittel |
Country Status (23)
Country | Link |
---|---|
US (2) | US7141564B2 (de) |
EP (1) | EP1399443B1 (de) |
JP (2) | JP4463565B2 (de) |
KR (1) | KR20040010654A (de) |
CN (1) | CN1535272A (de) |
AR (1) | AR038172A1 (de) |
AT (1) | ATE380812T1 (de) |
AU (1) | AU2002367697A1 (de) |
BR (1) | BR0210016A (de) |
CA (1) | CA2448525A1 (de) |
CO (1) | CO5540344A2 (de) |
CZ (1) | CZ20033202A3 (de) |
DE (1) | DE60224039T2 (de) |
ES (1) | ES2298439T3 (de) |
GB (1) | GB0112834D0 (de) |
HU (1) | HUP0400017A2 (de) |
IL (1) | IL158869A0 (de) |
MX (1) | MXPA03010790A (de) |
NO (1) | NO20035190D0 (de) |
PL (1) | PL367079A1 (de) |
TW (1) | TWI232219B (de) |
WO (1) | WO2003087098A1 (de) |
ZA (1) | ZA200308696B (de) |
Families Citing this family (72)
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SE9703377D0 (sv) * | 1997-09-18 | 1997-09-18 | Astra Ab | New compounds |
US6803369B1 (en) | 2000-07-25 | 2004-10-12 | Smithkline Beecham Corporation | Compounds and methods for the treatment of neoplastic disease |
US6962917B2 (en) | 2000-07-26 | 2005-11-08 | Smithkline Beecham P.L.C. | Aminopiperidine quinolines and their azaisosteric analogues with antibacterical activity |
EP1719770A3 (de) * | 2000-09-21 | 2008-03-05 | Smithkline Beecham Plc | Chinolinderivate als antibakterielle Mittel |
GB0031086D0 (en) * | 2000-12-20 | 2001-01-31 | Smithkline Beecham Plc | Medicaments |
GB0031088D0 (en) * | 2000-12-20 | 2001-01-31 | Smithkline Beecham Plc | Medicaments |
GB0101577D0 (en) | 2001-01-22 | 2001-03-07 | Smithkline Beecham Plc | Compounds |
GB0112834D0 (en) | 2001-05-25 | 2001-07-18 | Smithkline Beecham Plc | Medicaments |
GB0112836D0 (en) | 2001-05-25 | 2001-07-18 | Smithkline Beecham Plc | Medicaments |
GB0118238D0 (en) * | 2001-07-26 | 2001-09-19 | Smithkline Beecham Plc | Medicaments |
EP2181996A1 (de) | 2002-01-29 | 2010-05-05 | Glaxo Group Limited | Aminopiperidinderivate |
JP4508650B2 (ja) * | 2002-01-29 | 2010-07-21 | グラクソ グループ リミテッド | アミノピペリジン化合物、当該化合物の製法および当該化合物を含有する医薬組成物 |
AR040336A1 (es) * | 2002-06-26 | 2005-03-30 | Glaxo Group Ltd | Compuesto de piperidina, uso del mismo para la fabricacion de un medicamento, composicion farmaceutica que lo comprende y procedimiento para preparar dicho compuesto |
TW200406413A (en) * | 2002-06-26 | 2004-05-01 | Glaxo Group Ltd | Compounds |
DE60334016D1 (de) | 2002-11-05 | 2010-10-14 | Glaxo Group Ltd | Antibakterielle mittel |
US7232832B2 (en) * | 2002-11-05 | 2007-06-19 | Smithkline Beecham Corporation | Antibacterial agents |
US7491714B2 (en) | 2002-12-04 | 2009-02-17 | Glaxo Group Limited | Quinolines and nitrogenated derivatives thereof and their use as antibacterial agents |
DE60323133D1 (de) | 2002-12-13 | 2008-10-02 | Smithkline Beecham Corp | Cyclohexylverbindungen als ccr5-antagonisten |
AR042486A1 (es) * | 2002-12-18 | 2005-06-22 | Glaxo Group Ltd | Compuesto de quinolina y naftiridina halosustituido en la posicion 3, procedimiento para preparar el compuesto, composicion farmaceutica que lo comprende y su uso para preparar dicha composicion . |
DE102004023635A1 (de) | 2004-05-10 | 2006-04-13 | Grünenthal GmbH | Heteroarylsubstituierte Cyclohexyl-1,4-diamin-Derivate |
DE102004041163A1 (de) * | 2004-08-25 | 2006-03-02 | Morphochem Aktiengesellschaft für kombinatorische Chemie | Neue Verbindungen mit antibakterieller Aktivität |
US7592334B2 (en) * | 2005-01-25 | 2009-09-22 | Glaxo Group Limited | Antibacterial agents |
WO2006081179A1 (en) | 2005-01-25 | 2006-08-03 | Glaxo Group Limited | Antibacterial agents |
WO2006081289A2 (en) | 2005-01-25 | 2006-08-03 | Glaxo Group Limited | Antibacterial agents |
EP1846416A4 (de) | 2005-01-25 | 2009-07-01 | Glaxo Group Ltd | Antibakterielle wirkstoffe |
WO2006081264A1 (en) | 2005-01-25 | 2006-08-03 | Glaxo Group Limited | Antibacterial agents |
MY150958A (en) | 2005-06-16 | 2014-03-31 | Astrazeneca Ab | Compounds for the treatment of multi-drug resistant bacterial infections |
CN101374831B (zh) | 2006-01-26 | 2011-04-27 | 埃科特莱茵药品有限公司 | 四氢吡喃抗生素 |
ES2353829T3 (es) * | 2006-02-15 | 2011-03-07 | Actelion Pharmaceuticals Ltd. | Derivados antibioticos de etanol o de 1,2-etanodiolciclohexilo. |
JP2009527562A (ja) * | 2006-02-21 | 2009-07-30 | アムゲン インコーポレイティッド | ホスホジエステラーゼ10阻害剤としてのシンノリン誘導体 |
JP2009528365A (ja) * | 2006-02-28 | 2009-08-06 | アムゲン インコーポレイティッド | ホスホジエステラーゼ10阻害剤としてのシンノリン及びキナゾリン誘導体 |
JP2009529060A (ja) * | 2006-03-08 | 2009-08-13 | アムゲン インコーポレイティッド | ホスホジエステラーゼ10阻害剤としてのキノリン及びイソキノリン誘導体 |
JP2009532504A (ja) | 2006-04-06 | 2009-09-10 | グラクソ グループ リミテッド | 抗菌薬 |
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JP7430852B2 (ja) | 2019-12-20 | 2024-02-14 | エヌイミューン バイオファーマ インコーポレイテッド | ランチオニンc様タンパク質2リガンド、それを用いて調製される細胞、およびそれを使用する療法 |
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-
2001
- 2001-05-25 GB GBGB0112834.7A patent/GB0112834D0/en not_active Ceased
-
2002
- 2002-05-23 TW TW091110839A patent/TWI232219B/zh not_active IP Right Cessation
- 2002-05-23 AR ARP020101914A patent/AR038172A1/es not_active Application Discontinuation
- 2002-05-24 EP EP02807202A patent/EP1399443B1/de not_active Expired - Lifetime
- 2002-05-24 BR BR0210016-9A patent/BR0210016A/pt not_active IP Right Cessation
- 2002-05-24 CN CNA028146689A patent/CN1535272A/zh active Pending
- 2002-05-24 AU AU2002367697A patent/AU2002367697A1/en not_active Abandoned
- 2002-05-24 IL IL15886902A patent/IL158869A0/xx unknown
- 2002-05-24 AT AT02807202T patent/ATE380812T1/de not_active IP Right Cessation
- 2002-05-24 WO PCT/EP2002/005708 patent/WO2003087098A1/en active IP Right Grant
- 2002-05-24 HU HU0400017A patent/HUP0400017A2/hu unknown
- 2002-05-24 CA CA002448525A patent/CA2448525A1/en not_active Abandoned
- 2002-05-24 ES ES02807202T patent/ES2298439T3/es not_active Expired - Lifetime
- 2002-05-24 JP JP2003584054A patent/JP4463565B2/ja not_active Expired - Fee Related
- 2002-05-24 CZ CZ20033202A patent/CZ20033202A3/cs unknown
- 2002-05-24 PL PL02367079A patent/PL367079A1/xx not_active Application Discontinuation
- 2002-05-24 MX MXPA03010790A patent/MXPA03010790A/es unknown
- 2002-05-24 KR KR10-2003-7015379A patent/KR20040010654A/ko not_active Application Discontinuation
- 2002-05-24 US US10/478,154 patent/US7141564B2/en not_active Expired - Fee Related
- 2002-05-24 DE DE60224039T patent/DE60224039T2/de not_active Expired - Lifetime
-
2003
- 2003-11-07 ZA ZA200308696A patent/ZA200308696B/en unknown
- 2003-11-18 CO CO03101671A patent/CO5540344A2/es not_active Application Discontinuation
- 2003-11-21 NO NO20035190A patent/NO20035190D0/no not_active Application Discontinuation
-
2006
- 2006-11-22 US US11/604,045 patent/US20070135422A1/en not_active Abandoned
-
2009
- 2009-11-13 JP JP2009259981A patent/JP2010031057A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
MXPA03010790A (es) | 2004-03-02 |
JP2005519981A (ja) | 2005-07-07 |
US20070135422A1 (en) | 2007-06-14 |
EP1399443A1 (de) | 2004-03-24 |
IL158869A0 (en) | 2004-05-12 |
US20040171620A1 (en) | 2004-09-02 |
JP4463565B2 (ja) | 2010-05-19 |
ATE380812T1 (de) | 2007-12-15 |
CN1535272A (zh) | 2004-10-06 |
KR20040010654A (ko) | 2004-01-31 |
JP2010031057A (ja) | 2010-02-12 |
CZ20033202A3 (cs) | 2004-08-18 |
WO2003087098A1 (en) | 2003-10-23 |
ES2298439T3 (es) | 2008-05-16 |
PL367079A1 (en) | 2005-02-21 |
HUP0400017A2 (hu) | 2004-06-28 |
BR0210016A (pt) | 2004-06-15 |
DE60224039T2 (de) | 2008-11-27 |
ZA200308696B (en) | 2004-05-21 |
CA2448525A1 (en) | 2003-10-23 |
EP1399443B1 (de) | 2007-12-12 |
GB0112834D0 (en) | 2001-07-18 |
US7141564B2 (en) | 2006-11-28 |
AU2002367697A1 (en) | 2003-10-27 |
NO20035190D0 (no) | 2003-11-21 |
TWI232219B (en) | 2005-05-11 |
AR038172A1 (es) | 2005-01-05 |
CO5540344A2 (es) | 2005-07-29 |
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8381 | Inventor (new situation) |
Inventor name: BROOKS, GERALD, HARLOW, ESSEX CM19 5AW, GB Inventor name: DAVIES, DAVID THOMAS, HARLOW, ESSEX CM19 5AW, GB Inventor name: JONES, GRAHAM ELGIN, HARLOW, ESSEX CM19 5AW, GB Inventor name: MARKWELL, ROGER EDWARD, HARLOW, ESSEXCM19 5AW, GB Inventor name: PEARSON, NEIL DAVID, HARLOW, ESSEX CM19 5AW, GB |
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8364 | No opposition during term of opposition |