US7709A
(en)
|
|
1850-10-08 |
Chas S Gaylord |
Improved spring-grapple
|
US226A
(en)
|
|
1837-06-03 |
|
Samuel goss |
US541606A
(en)
|
|
1895-06-25 |
|
Sealed package |
EP0090505B1
(en)
|
1982-03-03 |
1990-08-08 |
Genentech, Inc. |
Human antithrombin iii, dna sequences therefor, expression vehicles and cloning vectors containing such sequences and cell cultures transformed thereby, a process for expressing human antithrombin iii, and pharmaceutical compositions comprising it
|
US4683195A
(en)
|
1986-01-30 |
1987-07-28 |
Cetus Corporation |
Process for amplifying, detecting, and/or-cloning nucleic acid sequences
|
US4978672A
(en)
|
1986-03-07 |
1990-12-18 |
Ciba-Geigy Corporation |
Alpha-heterocyclc substituted tolunitriles
|
US5225539A
(en)
|
1986-03-27 |
1993-07-06 |
Medical Research Council |
Recombinant altered antibodies and methods of making altered antibodies
|
WO1988001649A1
(en)
|
1986-09-02 |
1988-03-10 |
Genex Corporation |
Single polypeptide chain binding molecules
|
JP3101690B2
(ja)
|
1987-03-18 |
2000-10-23 |
エス・ビィ・2・インコーポレイテッド |
変性抗体の、または変性抗体に関する改良
|
EP0296122B1
(en)
|
1987-06-17 |
1993-09-29 |
Sandoz Ag |
Cyclosporins and their use as pharmaceuticals
|
US5606040A
(en)
|
1987-10-30 |
1997-02-25 |
American Cyanamid Company |
Antitumor and antibacterial substituted disulfide derivatives prepared from compounds possessing a methyl-trithio group
|
US5770701A
(en)
|
1987-10-30 |
1998-06-23 |
American Cyanamid Company |
Process for preparing targeted forms of methyltrithio antitumor agents
|
US5223409A
(en)
|
1988-09-02 |
1993-06-29 |
Protein Engineering Corp. |
Directed evolution of novel binding proteins
|
GB8823869D0
(en)
|
1988-10-12 |
1988-11-16 |
Medical Res Council |
Production of antibodies
|
US6362325B1
(en)
|
1988-11-07 |
2002-03-26 |
Advanced Research And Technology Institute, Inc. |
Murine 4-1BB gene
|
US6303121B1
(en)
|
1992-07-30 |
2001-10-16 |
Advanced Research And Technology |
Method of using human receptor protein 4-1BB
|
IL162181A
(en)
|
1988-12-28 |
2006-04-10 |
Pdl Biopharma Inc |
A method of producing humanized immunoglubulin, and polynucleotides encoding the same
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
US5208020A
(en)
|
1989-10-25 |
1993-05-04 |
Immunogen Inc. |
Cytotoxic agents comprising maytansinoids and their therapeutic use
|
US6150584A
(en)
|
1990-01-12 |
2000-11-21 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
US5427908A
(en)
|
1990-05-01 |
1995-06-27 |
Affymax Technologies N.V. |
Recombinant library screening methods
|
US6172197B1
(en)
|
1991-07-10 |
2001-01-09 |
Medical Research Council |
Methods for producing members of specific binding pairs
|
GB9015198D0
(en)
|
1990-07-10 |
1990-08-29 |
Brien Caroline J O |
Binding substance
|
US6255458B1
(en)
|
1990-08-29 |
2001-07-03 |
Genpharm International |
High affinity human antibodies and human antibodies against digoxin
|
US6582959B2
(en)
|
1991-03-29 |
2003-06-24 |
Genentech, Inc. |
Antibodies to vascular endothelial cell growth factor
|
US20030206899A1
(en)
|
1991-03-29 |
2003-11-06 |
Genentech, Inc. |
Vascular endothelial cell growth factor antagonists
|
CA2103059C
(en)
|
1991-06-14 |
2005-03-22 |
Paul J. Carter |
Method for making humanized antibodies
|
WO1994004679A1
(en)
|
1991-06-14 |
1994-03-03 |
Genentech, Inc. |
Method for making humanized antibodies
|
PT1024191E
(pt)
|
1991-12-02 |
2008-12-22 |
Medical Res Council |
Produção de auto-anticorpos a partir de reportórios de segmentos de anticorpo e exibidos em fagos
|
DK0666868T4
(da)
|
1992-10-28 |
2006-09-18 |
Genentech Inc |
Anvendelse af anti-VEGF-antistoffer til behandling af cancer
|
PL174721B1
(pl)
|
1992-11-13 |
1998-09-30 |
Idec Pharma Corp |
Przeciwciało monoklonalne anty-CD20
|
US5635483A
(en)
|
1992-12-03 |
1997-06-03 |
Arizona Board Of Regents Acting On Behalf Of Arizona State University |
Tumor inhibiting tetrapeptide bearing modified phenethyl amides
|
WO1994013804A1
(en)
|
1992-12-04 |
1994-06-23 |
Medical Research Council |
Multivalent and multispecific binding proteins, their manufacture and use
|
US5780588A
(en)
|
1993-01-26 |
1998-07-14 |
Arizona Board Of Regents |
Elucidation and synthesis of selected pentapeptides
|
US7138500B1
(en)
|
1993-05-07 |
2006-11-21 |
Immunex Corporation |
Antibodies to human 4-1BB
|
IL108501A
(en)
|
1994-01-31 |
1998-10-30 |
Mor Research Applic Ltd |
Antibodies and pharmaceutical compositions containing them
|
US5773001A
(en)
|
1994-06-03 |
1998-06-30 |
American Cyanamid Company |
Conjugates of methyltrithio antitumor agents and intermediates for their synthesis
|
US5688690A
(en)
|
1994-09-16 |
1997-11-18 |
The Wistar Institute Of Anatomy And Biology |
Human cytotoxic lymphocyte signal transduction surface protein (P38) and monoclonal antibodies thereto
|
IL117645A
(en)
|
1995-03-30 |
2005-08-31 |
Genentech Inc |
Vascular endothelial cell growth factor antagonists for use as medicaments in the treatment of age-related macular degeneration
|
AUPO591797A0
(en)
|
1997-03-27 |
1997-04-24 |
Commonwealth Scientific And Industrial Research Organisation |
High avidity polyvalent and polyspecific reagents
|
US5712374A
(en)
|
1995-06-07 |
1998-01-27 |
American Cyanamid Company |
Method for the preparation of substantiallly monomeric calicheamicin derivative/carrier conjugates
|
US5714586A
(en)
|
1995-06-07 |
1998-02-03 |
American Cyanamid Company |
Methods for the preparation of monomeric calicheamicin derivative/carrier conjugates
|
ATE283926T1
(de)
|
1995-09-11 |
2004-12-15 |
Kyowa Hakko Kogyo Kk |
Antikörper gegen die alpha-kette von humanem interleukin 5 rezeptor
|
JP2002514895A
(ja)
|
1995-09-28 |
2002-05-21 |
アレクション、ファーマスーティカルズ、インコーポレーテッド |
ブタ細胞相互作用タンパク質
|
US7357927B2
(en)
|
1996-03-12 |
2008-04-15 |
Human Genome Sciences, Inc. |
Death domain containing receptors
|
US6111090A
(en)
|
1996-08-16 |
2000-08-29 |
Schering Corporation |
Mammalian cell surface antigens; related reagents
|
JP4440344B2
(ja)
|
1996-08-16 |
2010-03-24 |
シェーリング コーポレイション |
哺乳動物細胞表面抗原;関連試薬
|
US6140076A
(en)
|
1996-12-06 |
2000-10-31 |
Schering Corporation |
Ig superfamily `dlair` receptors expressed in monocytes
|
US20060280140A9
(en)
*
|
1997-02-06 |
2006-12-14 |
Mahany Ronald L |
LOWER POWER WIRELESS BEACONING NETWORK SUPPORTING PROXIMAL FORMATION, SEPARATION AND REFORMATION OF WIRELESS LOCAL AREA NETWORKS (LAN's), AS TERMINALS MOVE IN AND OUT RANGE OF ONE ANOTHER
|
US6972323B1
(en)
|
1997-04-01 |
2005-12-06 |
Sankyo Company, Limited |
Anti-Fas antibodies
|
US20020032315A1
(en)
|
1997-08-06 |
2002-03-14 |
Manuel Baca |
Anti-vegf antibodies
|
PT973804E
(pt)
|
1997-04-07 |
2007-03-30 |
Genentech Inc |
Anticorpos anti-vegf
|
ES2236634T3
(es)
|
1997-04-07 |
2005-07-16 |
Genentech, Inc. |
Anticuerpos anti-vegf.
|
US6884879B1
(en)
|
1997-04-07 |
2005-04-26 |
Genentech, Inc. |
Anti-VEGF antibodies
|
ES2258817T3
(es)
|
1997-05-21 |
2006-09-01 |
Biovation Limited |
Metodo para la produccion de proteinas no inmunogenas.
|
CO4940418A1
(es)
|
1997-07-18 |
2000-07-24 |
Novartis Ag |
Modificacion de cristal de un derivado de n-fenil-2- pirimidinamina, procesos para su fabricacion y su uso
|
JP2001516766A
(ja)
*
|
1997-09-19 |
2001-10-02 |
デイナ−ファーバー キャンサー インスティチュート,インコーポレイテッド |
免疫反応の細胞内発現抗体仲介制御
|
GB9722131D0
(en)
*
|
1997-10-20 |
1997-12-17 |
Medical Res Council |
Method
|
AU1102399A
(en)
|
1997-10-21 |
1999-05-10 |
Human Genome Sciences, Inc. |
Human tumor necrosis factor receptor-like proteins tr11, tr11sv1, and tr11sv2
|
WO1999040196A1
(en)
|
1998-02-09 |
1999-08-12 |
Genentech, Inc. |
Novel tumor necrosis factor receptor homolog and nucleic acids encoding the same
|
DE19835635C2
(de)
|
1998-08-06 |
2000-05-25 |
Knorr Bremse Systeme |
Relaisventil für Druckluftbremssysteme von Schienenfahrzeugen
|
US6818749B1
(en)
|
1998-10-31 |
2004-11-16 |
The United States Of America As Represented By The Department Of Health And Human Services |
Variants of humanized anti carcinoma monoclonal antibody cc49
|
US7888477B2
(en)
|
1998-12-17 |
2011-02-15 |
Corixa Corporation |
Ovarian cancer-associated antibodies and kits
|
US6737056B1
(en)
|
1999-01-15 |
2004-05-18 |
Genentech, Inc. |
Polypeptide variants with altered effector function
|
US6703020B1
(en)
|
1999-04-28 |
2004-03-09 |
Board Of Regents, The University Of Texas System |
Antibody conjugate methods for selectively inhibiting VEGF
|
JP2003504343A
(ja)
|
1999-07-12 |
2003-02-04 |
ジェネンテック・インコーポレーテッド |
腫瘍壊死因子リガンド/レセプター相同体による血管形成及び心血管形成の促進と抑制
|
JP4896327B2
(ja)
|
1999-08-23 |
2012-03-14 |
ダナ−ファーバー キャンサー インスティテュート,インコーポレイテッド |
Pd−1、b7−4の受容体、およびその使用
|
AU767394C
(en)
|
1999-12-29 |
2005-04-21 |
Immunogen, Inc. |
Cytotoxic agents comprising modified doxorubicins and daunorubicins and their therapeutic use
|
GB0018891D0
(en)
|
2000-08-01 |
2000-09-20 |
Novartis Ag |
Organic compounds
|
JP2003524644A
(ja)
|
2000-02-01 |
2003-08-19 |
タノックス インコーポレイテッド |
Cd40−結合性apc−活性化分子
|
WO2001083755A2
(en)
|
2000-04-28 |
2001-11-08 |
La Jolla Institute For Allergy And Immunology |
Human anti-cd40 antibodies and methods of making and using same
|
US6696620B2
(en)
|
2000-05-02 |
2004-02-24 |
Epicyte Pharmaceutical, Inc. |
Immunoglobulin binding protein arrays in eukaryotic cells
|
CA2412377A1
(en)
|
2000-06-06 |
2001-12-13 |
Bristol-Myers Squibb Company |
B7-related nucleic acids and polypeptides and their uses for immunomodulation
|
DE60140252D1
(de)
|
2000-06-22 |
2009-12-03 |
Genentech Inc |
Agonistische monoklonale antikörper gegen trkc
|
US7288390B2
(en)
*
|
2000-08-07 |
2007-10-30 |
Centocor, Inc. |
Anti-dual integrin antibodies, compositions, methods and uses
|
US6596541B2
(en)
|
2000-10-31 |
2003-07-22 |
Regeneron Pharmaceuticals, Inc. |
Methods of modifying eukaryotic cells
|
ES2295228T3
(es)
|
2000-11-30 |
2008-04-16 |
Medarex, Inc. |
Roedores transcromosomicos transgenicos para la preparacion de anticuerpos humanos.
|
EP1355948B1
(en)
|
2001-01-12 |
2009-03-11 |
Molecules of Man AB |
Materials and methods for treatment of hepatitis c
|
US6995162B2
(en)
|
2001-01-12 |
2006-02-07 |
Amgen Inc. |
Substituted alkylamine derivatives and methods of use
|
AR036993A1
(es)
|
2001-04-02 |
2004-10-20 |
Wyeth Corp |
Uso de agentes que modulan la interaccion entre pd-1 y sus ligandos en la submodulacion de respuestas inmunologicas
|
US7667004B2
(en)
|
2001-04-17 |
2010-02-23 |
Abmaxis, Inc. |
Humanized antibodies against vascular endothelial growth factor
|
AU2002368077B2
(en)
|
2001-07-12 |
2010-03-04 |
Jefferson Foote |
Super humanized antibodies
|
US20030226155A1
(en)
*
|
2001-08-30 |
2003-12-04 |
Biorexis Pharmaceutical Corporation |
Modified transferrin-antibody fusion proteins
|
US20040142325A1
(en)
*
|
2001-09-14 |
2004-07-22 |
Liat Mintz |
Methods and systems for annotating biomolecular sequences
|
KR20090087139A
(ko)
|
2001-10-30 |
2009-08-14 |
노파르티스 아게 |
Flt3 수용체 티로신 키나아제 활성의 억제제로서의 스타우로스포린 유도체
|
AR039067A1
(es)
|
2001-11-09 |
2005-02-09 |
Pfizer Prod Inc |
Anticuerpos para cd40
|
EA011488B1
(ru)
|
2002-02-01 |
2009-04-28 |
Ариад Джин Терапьютикс, Инк. |
Фосфорсодержащие соединения и их получение
|
KR100984613B1
(ko)
|
2002-03-13 |
2010-09-30 |
어레이 바이오파마 인크. |
Mek 억제제로서의 n3 알킬화 벤즈이미다졸 유도체
|
ES2295639T3
(es)
|
2002-06-13 |
2008-04-16 |
Crucell Holland B.V. |
Agonistas del receptor ox40=(=cd134) y uso terapeutico descripcion.
|
WO2007001459A2
(en)
|
2004-11-15 |
2007-01-04 |
Washington University |
Compositions and methods for modulating lymphocyte activity
|
US8546541B2
(en)
|
2002-06-20 |
2013-10-01 |
Washington University |
Compositions and methods for modulating lymphocyte activity
|
ATE481985T1
(de)
|
2002-07-03 |
2010-10-15 |
Ono Pharmaceutical Co |
Immunpotenzierende zusammensetzungen
|
GB0215676D0
(en)
|
2002-07-05 |
2002-08-14 |
Novartis Ag |
Organic compounds
|
US20040047858A1
(en)
|
2002-09-11 |
2004-03-11 |
Blumberg Richard S. |
Therapeutic anti-BGP(C-CAM1) antibodies and uses thereof
|
EP1560593B1
(en)
|
2002-10-25 |
2016-04-20 |
Genentech, Inc. |
Novel composition and methods for the treatment of immune related diseases
|
ATE466885T1
(de)
|
2002-11-15 |
2010-05-15 |
Novartis Vaccines & Diagnostic |
Methoden zur verhinderung und behandlung von krebs-metastasierung und mit krebs-metastasierung einhergehendem knochenverlust
|
CA2508660C
(en)
|
2002-12-23 |
2013-08-20 |
Wyeth |
Antibodies against pd-1 and uses therefor
|
CN1771235B
(zh)
|
2003-02-11 |
2010-04-28 |
弗奈利斯(剑桥)有限公司 |
异噁唑化合物
|
EP1592713A2
(en)
*
|
2003-02-13 |
2005-11-09 |
Pharmacia Corporation |
Antibodies to c-met for the treatment of cancers
|
US20070048740A1
(en)
|
2003-02-14 |
2007-03-01 |
Research Association For Biotechnology |
Full-length cDNA
|
US20050009136A1
(en)
*
|
2003-02-19 |
2005-01-13 |
Dyax Corporation |
PAPP-A ligands
|
ES2330224T3
(es)
*
|
2003-04-17 |
2009-12-07 |
Cytec Technology Corp. |
Composicion y proceso para la extraccion de metales con disolvente usando agentes de extraccion de aldoxima o cetoxima.
|
US20050025763A1
(en)
|
2003-05-08 |
2005-02-03 |
Protein Design Laboratories, Inc. |
Therapeutic use of anti-CS1 antibodies
|
WO2004107618A2
(en)
|
2003-05-23 |
2004-12-09 |
Wyeth |
Gitr ligand and gitr ligand-related molecules and antibodies and uses thereof
|
KR20170073698A
(ko)
|
2003-05-30 |
2017-06-28 |
제넨테크, 인크. |
항-vegf 항체를 사용한 치료
|
RU2404993C2
(ru)
|
2003-07-02 |
2010-11-27 |
Иннейт Фарма |
Композиции и способы регуляции клеточной активности nk
|
EP1660126A1
(en)
|
2003-07-11 |
2006-05-31 |
Schering Corporation |
Agonists or antagonists of the clucocorticoid-induced tumour necrosis factor receptor (gitr) or its ligand for the treatment of immune disorders, infections and cancer
|
US20050106667A1
(en)
|
2003-08-01 |
2005-05-19 |
Genentech, Inc |
Binding polypeptides with restricted diversity sequences
|
WO2005044853A2
(en)
|
2003-11-01 |
2005-05-19 |
Genentech, Inc. |
Anti-vegf antibodies
|
US7758859B2
(en)
|
2003-08-01 |
2010-07-20 |
Genentech, Inc. |
Anti-VEGF antibodies
|
US7288638B2
(en)
|
2003-10-10 |
2007-10-30 |
Bristol-Myers Squibb Company |
Fully human antibodies against human 4-1BB
|
EP1682103A1
(en)
|
2003-10-27 |
2006-07-26 |
Novartis AG |
Indolyl-pyrroledione derivatives for the treatment of neurological and vascular disorders related to beta-amyloid generation and/or aggregation
|
SG195524A1
(en)
|
2003-11-06 |
2013-12-30 |
Seattle Genetics Inc |
Monomethylvaline compounds capable of conjugation to ligands
|
AU2004287722A1
(en)
|
2003-11-11 |
2005-05-19 |
Chugai Seiyaku Kabushiki Kaisha |
Humanized anti-CD47 antibody
|
KR20060120161A
(ko)
*
|
2003-11-28 |
2006-11-24 |
아스트라제네카 아베 |
항체
|
WO2005055808A2
(en)
|
2003-12-02 |
2005-06-23 |
Genzyme Corporation |
Compositions and methods to diagnose and treat lung cancer
|
AU2005207946A1
(en)
|
2004-01-23 |
2005-08-11 |
Amgen Inc. |
Quinoline quinazoline pyridine and pyrimidine counds and their use in the treatment of inflammation angiogenesis and cancer
|
US7973139B2
(en)
*
|
2004-03-26 |
2011-07-05 |
Human Genome Sciences, Inc. |
Antibodies against nogo receptor
|
GB0409799D0
(en)
|
2004-04-30 |
2004-06-09 |
Isis Innovation |
Method of generating improved immune response
|
RS55551B1
(sr)
|
2004-05-13 |
2017-05-31 |
Icos Corp |
Hinazolinoni kao inhibitori humane fosfatidilinozitol 3-kinaze delta
|
EP1765402A2
(en)
|
2004-06-04 |
2007-03-28 |
Duke University |
Methods and compositions for enhancement of immunity by in vivo depletion of immunosuppressive cell activity
|
PL1761528T3
(pl)
|
2004-06-11 |
2008-05-30 |
Japan Tobacco Inc |
Pochodne 5-amino-2,4,7-triokso-3,4,7,8-tetrahydro-2H-pirydo[2,3-D]pirymidyny i związki pokrewne do leczenia raka
|
US7378423B2
(en)
|
2004-06-11 |
2008-05-27 |
Japan Tobacco Inc. |
Pyrimidine compound and medical use thereof
|
GB0512324D0
(en)
|
2005-06-16 |
2005-07-27 |
Novartis Ag |
Organic compounds
|
US20060009360A1
(en)
|
2004-06-25 |
2006-01-12 |
Robert Pifer |
New adjuvant composition
|
US20060099203A1
(en)
|
2004-11-05 |
2006-05-11 |
Pease Larry R |
B7-DC binding antibody
|
JP2008511337A
(ja)
|
2004-09-02 |
2008-04-17 |
ジェネンテック・インコーポレーテッド |
ヘテロ多量体分子
|
DK1817055T3
(da)
|
2004-11-10 |
2013-04-08 |
Diadexus Inc |
Ovr110-antistofsammensætninger og fremgangsmåder til anvendelse heraf
|
ZA200705980B
(en)
|
2005-01-07 |
2009-01-28 |
Lexicon Pharmaceuticals Inc |
Monoclonal antibodies against angiopoietin-like protein 4 (ANGPTL4)
|
WO2006096527A2
(en)
|
2005-03-04 |
2006-09-14 |
Diversa Corporation |
Nucleic acids and proteins and methods for making and using them
|
EP2374887A3
(en)
|
2005-03-25 |
2012-07-18 |
National Research Council Of Canada |
Method for isolation of soluble polypeptides
|
ES2657443T3
(es)
|
2005-03-25 |
2018-03-05 |
Gitr, Inc. |
Anticuerpos anti-GITR y usos de los mismos
|
WO2006106905A1
(ja)
|
2005-03-31 |
2006-10-12 |
Chugai Seiyaku Kabushiki Kaisha |
会合制御によるポリペプチド製造方法
|
SI2439273T1
(sl)
|
2005-05-09 |
2019-05-31 |
Ono Pharmaceutical Co., Ltd. |
Človeška monoklonska protitelesa za programirano smrt 1 (PD-1) in postopki za zdravljenje raka z uporabo protiteles proti PD-1 samostojno ali v kombinaciji z ostalimi imunoterapevtiki
|
SI1879573T1
(sl)
|
2005-05-10 |
2013-04-30 |
Incyte Corporation Experimental Station |
Modulatorji indolamin 2,3-dioksigenaze in postopki za uporabo le-te
|
GB0510390D0
(en)
|
2005-05-20 |
2005-06-29 |
Novartis Ag |
Organic compounds
|
EP1885399B1
(en)
|
2005-05-26 |
2010-10-20 |
Seattle Genetics, Inc. |
Humanized anti-cd40 antibodies and their methods of use
|
CN104436190A
(zh)
|
2005-06-08 |
2015-03-25 |
达纳-法伯癌症研究院公司 |
通过抑制程序性细胞死亡1(pd-1)途经治疗持续性感染和癌症的方法及组合物
|
JP2006345852A
(ja)
*
|
2005-06-16 |
2006-12-28 |
Virxsys Corp |
抗体複合体
|
DE102005028778A1
(de)
|
2005-06-22 |
2006-12-28 |
SUNJÜT Deutschland GmbH |
Mehrlagige Folie mit einer Barriere- und einer antistatischen Lage
|
CN101248089A
(zh)
|
2005-07-01 |
2008-08-20 |
米德列斯公司 |
抗程序性死亡配体1(pd-l1)的人单克隆抗体
|
JP4557003B2
(ja)
|
2005-07-01 |
2010-10-06 |
株式会社村田製作所 |
多層セラミック基板およびその製造方法ならびに多層セラミック基板作製用複合グリーンシート
|
WO2007011941A2
(en)
*
|
2005-07-18 |
2007-01-25 |
Amgen Inc. |
Human anti-b7rp1 neutralizing antibodies
|
PE20070427A1
(es)
|
2005-08-30 |
2007-04-21 |
Novartis Ag |
Compuestos derivados de benzimidazoles sustituidos como inhibidores de tirosina quinasas
|
SG10201402712QA
(en)
|
2005-08-31 |
2014-08-28 |
Merck Sharp & Dohme |
Engineered anti-il-23 antibodies
|
JP5714212B2
(ja)
|
2005-12-08 |
2015-05-07 |
メダレックス・リミテッド・ライアビリティ・カンパニーMedarex, L.L.C. |
O8eに対するヒトモノクローナル抗体
|
ES2612196T3
(es)
|
2005-12-13 |
2017-05-12 |
Incyte Holdings Corporation |
Pirrolo[2,3-b]piridinas y pirrolo[2,3-b]pirimidinas sustituidas con heteroarilo como inhibidores de quinasas Janus
|
EP1981969A4
(en)
|
2006-01-19 |
2009-06-03 |
Genzyme Corp |
ANTI-GITRANT ANTIBODIES FOR THE TREATMENT OF CANCER
|
JO2660B1
(en)
|
2006-01-20 |
2012-06-17 |
نوفارتيس ايه جي |
Pi-3 inhibitors and methods of use
|
CN101495136A
(zh)
|
2006-02-15 |
2009-07-29 |
英克隆***公司 |
抗体配制品
|
ES2395969T3
(es)
|
2006-03-24 |
2013-02-18 |
Merck Patent Gmbh |
Dominios de proteínas heterodiméricas genéticamente modificados
|
UA93548C2
(uk)
|
2006-05-05 |
2011-02-25 |
Айерем Елелсі |
Сполуки та композиції як модулятори хеджхогівського сигнального шляху
|
JP2009541275A
(ja)
|
2006-06-22 |
2009-11-26 |
ノボ・ノルデイスク・エー/エス |
二重特異性抗体の生産
|
PE20110218A1
(es)
|
2006-08-02 |
2011-04-01 |
Novartis Ag |
DERIVADOS DE 2-OXO-ETIL-AMINO-PROPIONAMIDA-PIRROLIDIN-2-IL-SUSTITUIDOS COMO INHIBIDORES DEL ENLACE DE LA PROTEINA Smac AL INHIBIDOR DE LA PROTEINA DE APOPTOSIS
|
ES2444065T3
(es)
|
2006-08-18 |
2014-02-24 |
Novartis Ag |
Anticuerpo específico para PRLR y usos del mismo
|
KR101428116B1
(ko)
|
2006-08-21 |
2014-08-07 |
제넨테크, 인크. |
아자-벤조푸라닐 화합물 및 사용 방법
|
MX2009002694A
(es)
*
|
2006-09-29 |
2009-03-24 |
Hoffmann La Roche |
Anticuerpos dirigidos contra ccr5 y usos de los mismos.
|
GB0620894D0
(en)
|
2006-10-20 |
2006-11-29 |
Univ Southampton |
Human immune therapies using a CD27 agonist alone or in combination with other immune modulators
|
AR063840A1
(es)
|
2006-11-15 |
2009-02-25 |
Medarex Inc |
Anticuerpos humanos monoclonales para btla y metodos de uso
|
JP5208123B2
(ja)
|
2006-12-08 |
2013-06-12 |
アイアールエム・リミテッド・ライアビリティ・カンパニー |
タンパク質キナーゼ阻害剤としての化合物および組成物
|
US20080226635A1
(en)
|
2006-12-22 |
2008-09-18 |
Hans Koll |
Antibodies against insulin-like growth factor I receptor and uses thereof
|
AU2007339762B2
(en)
|
2006-12-27 |
2011-03-31 |
The Johns Hopkins University |
Compositions and methods for treating inflammation and auto-immune diseases
|
EP1987839A1
(en)
|
2007-04-30 |
2008-11-05 |
I.N.S.E.R.M. Institut National de la Sante et de la Recherche Medicale |
Cytotoxic anti-LAG-3 monoclonal antibody and its use in the treatment or prevention of organ transplant rejection and autoimmune disease
|
KR101586617B1
(ko)
|
2007-06-18 |
2016-01-20 |
머크 샤프 앤 도메 비.브이. |
사람 프로그램된 사멸 수용체 pd-1에 대한 항체
|
EP3124046B1
(en)
|
2007-07-12 |
2019-12-25 |
GITR, Inc. |
Combination therapies employing gitr binding molecules
|
WO2009018386A1
(en)
|
2007-07-31 |
2009-02-05 |
Medimmune, Llc |
Multispecific epitope binding proteins and uses thereof
|
EP2195347A1
(en)
|
2007-08-17 |
2010-06-16 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Method for treating and diagnosing hematologic malignancies
|
US8748356B2
(en)
|
2007-10-19 |
2014-06-10 |
Janssen Biotech, Inc. |
Methods for use in human-adapting monoclonal antibodies
|
US8163285B2
(en)
|
2007-11-02 |
2012-04-24 |
Novartis Ag |
Nogo-A binding molecules and pharmaceutical use thereof
|
PT2851374T
(pt)
|
2007-12-14 |
2017-06-20 |
Pfizer |
Moléculas de ligação ao recetor humano ox40
|
RU2441004C1
(ru)
|
2007-12-19 |
2012-01-27 |
Дженентек, Инк. |
5-анилиноимидазопиридины и способы их применения
|
JP2011507519A
(ja)
|
2007-12-19 |
2011-03-10 |
セントコア・オーソ・バイオテツク・インコーポレーテツド |
pIX又はpVIIへの融合を介したヒトデノボpIXファージディスプレイライブラリの設計及び作製、ベクター、抗体、及び方法
|
US9266967B2
(en)
|
2007-12-21 |
2016-02-23 |
Hoffmann-La Roche, Inc. |
Bivalent, bispecific antibodies
|
US8242247B2
(en)
|
2007-12-21 |
2012-08-14 |
Hoffmann-La Roche Inc. |
Bivalent, bispecific antibodies
|
US8227577B2
(en)
|
2007-12-21 |
2012-07-24 |
Hoffman-La Roche Inc. |
Bivalent, bispecific antibodies
|
US20090162359A1
(en)
|
2007-12-21 |
2009-06-25 |
Christian Klein |
Bivalent, bispecific antibodies
|
EP2262837A4
(en)
|
2008-03-12 |
2011-04-06 |
Merck Sharp & Dohme |
PD-1 BINDING PROTEINS
|
JP5547099B2
(ja)
|
2008-03-14 |
2014-07-09 |
インテリカイン, エルエルシー |
キナーゼ阻害剤および使用方法
|
AR070924A1
(es)
|
2008-03-19 |
2010-05-12 |
Novartis Ag |
Formas cristalinas y dos formas solvatadas de sales del acido lactico de 4- amino -5- fluoro-3-(5-(4-metilpiperazin-1-il ) -1h- bencimidazol-2-il) quinolin -2-(1h) - ona
|
FR2929946B1
(fr)
|
2008-04-11 |
2010-05-28 |
Pf Medicament |
Nouveaux anticorps anti-cd151 et leur utilisation pour le traitement du cancer
|
US20110229460A1
(en)
|
2008-05-01 |
2011-09-22 |
Gtc Biotherapeutics, Inc. |
anti-cd137 antibody as an agent in the treatment of inflammatory conditions
|
UY31929A
(es)
|
2008-06-25 |
2010-01-05 |
Irm Llc |
Compuestos y composiciones como inhibidores de cinasa
|
AU2009266873A1
(en)
|
2008-07-02 |
2010-01-07 |
Emergent Product Development Seattle, Llc |
TGF-beta antagonist multi-target binding proteins
|
AU2009268611B2
(en)
|
2008-07-08 |
2015-04-09 |
Intellikine, Llc |
Kinase inhibitors and methods of use
|
US20100041663A1
(en)
|
2008-07-18 |
2010-02-18 |
Novartis Ag |
Organic Compounds as Smo Inhibitors
|
WO2010017103A2
(en)
|
2008-08-04 |
2010-02-11 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Servic |
Fully human anti-human nkg2d monoclonal antibodies
|
AR072999A1
(es)
|
2008-08-11 |
2010-10-06 |
Medarex Inc |
Anticuerpos humanos que se unen al gen 3 de activacion linfocitaria (lag-3) y los usos de estos
|
CN102186856B
(zh)
|
2008-08-22 |
2014-09-24 |
诺华股份有限公司 |
作为cdk抑制剂的吡咯并嘧啶化合物
|
PL2344474T3
(pl)
|
2008-09-02 |
2016-03-31 |
Novartis Ag |
Pochodne pikolinamidu jako inhibitory kinaz
|
UA104147C2
(uk)
|
2008-09-10 |
2014-01-10 |
Новартис Аг |
Похідна піролідиндикарбонової кислоти та її застосування у лікуванні проліферативних захворювань
|
WO2010030002A1
(ja)
|
2008-09-12 |
2010-03-18 |
国立大学法人三重大学 |
外来性gitrリガンド発現細胞
|
WO2010029435A1
(en)
|
2008-09-12 |
2010-03-18 |
Isis Innovation Limited |
Pd-1 specific antibodies and uses thereof
|
EP2342228B1
(en)
|
2008-09-12 |
2017-09-06 |
Oxford University Innovation Limited |
Pd-1 specific antibodies and uses thereof
|
SI2342226T1
(sl)
|
2008-09-26 |
2016-11-30 |
Dana-Farber Cancer Institute Inc. |
Humana protitelesa proti PD-1, PD-L1 in PD-L2 in njihove uporabe
|
EP2346508B1
(en)
|
2008-09-26 |
2016-08-24 |
Intellikine, LLC |
Heterocyclic kinase inhibitors
|
KR101050829B1
(ko)
|
2008-10-02 |
2011-07-20 |
서울대학교산학협력단 |
항 pd-1 항체 또는 항 pd-l1 항체를 포함하는 항암제
|
WO2010045340A1
(en)
|
2008-10-14 |
2010-04-22 |
Centocor Ortho Biotech Inc. |
Methods of humanizing and affinity-maturing antibodies
|
JO3096B1
(ar)
*
|
2008-11-07 |
2017-03-15 |
Imclone Llc |
الأجسام المضادة لمستقبل ii مضاد tgfb
|
CA2744937C
(en)
|
2008-11-28 |
2017-02-28 |
Novartis Ag |
Pharmaceutical combination comprising a hsp 90 inhibitor and a mtor inhibitor
|
UA109108C2
(uk)
|
2008-12-09 |
2015-07-27 |
Дженентек, Інк. |
Антитіло до pd-l1 та його застосування для посилення функції t-клітин
|
WO2010078580A2
(en)
|
2009-01-05 |
2010-07-08 |
The Johns Hopkins University |
Immunotherapy for contact dermatitis using co-signal regulation
|
WO2010083178A1
(en)
*
|
2009-01-16 |
2010-07-22 |
Monsanto Technology Llc |
Isolated novel nucleic acid and protein molecules from corn and methods of using those molecules to generate transgenic plants with enhanced agronomic traits
|
EP2210903A1
(en)
|
2009-01-21 |
2010-07-28 |
Monoclonal Antibodies Therapeutics |
Anti-CD160 monoclonal antibodies and uses thereof
|
ES2629337T3
(es)
|
2009-02-09 |
2017-08-08 |
Inserm - Institut National De La Santé Et De La Recherche Médicale |
Anticuerpos contra PD-1 y anticuerpos contra PD-L1 y usos de los mismos
|
UA103918C2
(en)
|
2009-03-02 |
2013-12-10 |
Айерем Элелси |
N-(hetero)aryl, 2-(hetero)aryl-substituted acetamides for use as wnt signaling modulators
|
AR075989A1
(es)
*
|
2009-04-10 |
2011-05-11 |
Lilly Co Eli |
Anticuerpo dkk -1 (dickkopf-1) humano disenado por ingenieria
|
WO2010129304A2
(en)
|
2009-04-27 |
2010-11-11 |
Oncomed Pharmaceuticals, Inc. |
Method for making heteromultimeric molecules
|
RU2016134843A
(ru)
|
2009-04-30 |
2018-12-11 |
Тел Хашомер Медикал Рисерч Инфрастракче Энд Сервисиз Лтд. |
Антитела к ceacam1 и способы их использования
|
RU2420587C2
(ru)
|
2009-06-25 |
2011-06-10 |
Открытое акционерное общество "Всероссийский научный Центр молекулярной диагностики и лечения" (ОАО ВНЦМДЛ) |
ГУМАНИЗИРОВАННЫЕ АНТИТЕЛА И Fab, СВЯЗЫВАЮЩИЕСЯ С АНТИГЕНОМ F1 ИЗ Yersinia pestis, И СПОСОБ ИХ ПОЛУЧЕНИЯ С ИСПОЛЬЗОВАНИЕМ ДРОЖЖЕЙ
|
UA105794C2
(uk)
|
2009-06-26 |
2014-06-25 |
Новартіс Аг |
1,3-ДИЗАМІЩЕНІ ПОХІДНІ ІМІДАЗОЛІДИН-2-ОНУ ЯК ІНГІБІТОРИ Cyp17
|
AR077594A1
(es)
|
2009-07-31 |
2011-09-07 |
Organon Nv |
Anticuerpos completamente humanos para btla (atenuante de linfocitos b y t)
|
JO3002B1
(ar)
|
2009-08-28 |
2016-09-05 |
Irm Llc |
مركبات و تركيبات كمثبطات كيناز بروتين
|
EP2473531A4
(en)
|
2009-09-03 |
2013-05-01 |
Merck Sharp & Dohme |
ANTI-GITRANT ANTIBODIES
|
GB0919054D0
(en)
|
2009-10-30 |
2009-12-16 |
Isis Innovation |
Treatment of obesity
|
ES2646863T3
(es)
*
|
2009-11-24 |
2017-12-18 |
Medimmune Limited |
Agentes de unión específica contra B7-H1
|
PT2506871T
(pt)
|
2009-11-30 |
2016-11-07 |
Janssen Biotech Inc |
Mutantes de fc de anticorpos com funções efetoras inutilizadas
|
US8440693B2
(en)
|
2009-12-22 |
2013-05-14 |
Novartis Ag |
Substituted isoquinolinones and quinazolinones
|
EP3112382A1
(en)
|
2009-12-29 |
2017-01-04 |
Emergent Product Development Seattle, LLC |
Heterodimer binding proteins and uses thereof
|
UY33227A
(es)
|
2010-02-19 |
2011-09-30 |
Novartis Ag |
Compuestos de pirrolopirimidina como inhibidores de la cdk4/6
|
US8859736B2
(en)
*
|
2010-02-19 |
2014-10-14 |
The Board Of Regents Of The University Of Oklahoma |
Monoclonal antibodies that inhibit the wnt signaling pathway and methods of production and use thereof
|
LT2542256T
(lt)
|
2010-03-04 |
2019-10-25 |
Macrogenics Inc |
Su b7-h3 reaguojantys antikūnai, jų imunologiškai aktyvūs fragmentai ir jų naudojimas
|
US8993731B2
(en)
|
2010-03-11 |
2015-03-31 |
Ucb Biopharma Sprl |
PD-1 antibody
|
US9150663B2
(en)
|
2010-04-20 |
2015-10-06 |
Genmab A/S |
Heterodimeric antibody Fc-containing proteins and methods for production thereof
|
EP2566514A4
(en)
*
|
2010-05-03 |
2013-11-27 |
Abbvie Inc |
METHODS OF INHIBITING FIBROSIS WITH ANTI-PAI-1 ANTIBODIES
|
LT3789038T
(lt)
*
|
2010-05-14 |
2022-12-12 |
The Board Of Trustees Of The Leland Stanford Junior University |
Humanizuoti ir chimeriniai monokloniniai antikūnai prieš cd47
|
EP2581113B1
(en)
|
2010-06-11 |
2018-05-09 |
Kyowa Hakko Kirin Co., Ltd. |
Anti-tim-3 antibody
|
JP2013532153A
(ja)
*
|
2010-06-18 |
2013-08-15 |
ザ ブリガム アンド ウィメンズ ホスピタル インコーポレイテッド |
慢性免疫病に対する免疫治療のためのtim−3およびpd−1に対する二重特異性抗体
|
JP6057896B2
(ja)
|
2010-08-20 |
2017-01-11 |
ノバルティス アーゲー |
上皮細胞増殖因子受容体3(her3)に対する抗体
|
EP2609118B1
(en)
|
2010-08-23 |
2017-01-18 |
Board Of Regents, The University Of Texas System |
Anti-ox40 antibodies and methods of using the same
|
RU2551963C2
(ru)
|
2010-09-09 |
2015-06-10 |
Пфайзер Инк. |
Молекулы, связывающиеся с 4-1вв
|
CA2812389C
(en)
|
2010-09-27 |
2019-12-31 |
John Kehoe |
Antibodies binding human collagen ii
|
EP3281954A1
(en)
*
|
2010-11-04 |
2018-02-14 |
Boehringer Ingelheim International GmbH |
Anti-il-23 antibodies
|
JP6167040B2
(ja)
|
2010-11-05 |
2017-07-19 |
ザイムワークス,インコーポレイテッド |
Fcドメイン中に突然変異を有する、安定したヘテロ二量体抗体の設計
|
DE102010052101A1
(de)
|
2010-11-20 |
2012-05-24 |
Schaeffler Technologies Gmbh & Co. Kg |
Lagervorrichtung mit einem Fanglager
|
GB201020995D0
(en)
|
2010-12-10 |
2011-01-26 |
Bioinvent Int Ab |
Biological materials and uses thereof
|
CN111246576B
(zh)
|
2011-03-31 |
2020-12-25 |
华为技术有限公司 |
时分双工***中子帧配置的方法、基站及用户设备
|
MX341076B
(es)
|
2011-03-31 |
2016-08-04 |
Merck Sharp & Dohme |
Formulaciones estables de anticuerpos para el receptor humano pd-1 de meurte programada y tratamientos relacionados.
|
DK2699264T3
(en)
|
2011-04-20 |
2018-06-25 |
Medimmune Llc |
ANTIBODIES AND OTHER MOLECULES BINDING B7-H1 AND PD-1
|
WO2012145568A1
(en)
|
2011-04-21 |
2012-10-26 |
Albert Einstein College Of Medicine Of Yeshiva University |
Antibodies to human b7x for treatment of metastatic cancer
|
CN103796680A
(zh)
|
2011-06-21 |
2014-05-14 |
约翰霍普金斯大学 |
用于增强针对赘生物的基于免疫的治疗的聚焦放射
|
US8841418B2
(en)
*
|
2011-07-01 |
2014-09-23 |
Cellerant Therapeutics, Inc. |
Antibodies that specifically bind to TIM3
|
CA2843595C
(en)
|
2011-08-01 |
2022-10-18 |
Genentech, Inc. |
Methods of treating cancer using pd-1 axis binding antagonists and mek inhibitors
|
AU2012299421B2
(en)
|
2011-08-23 |
2016-02-04 |
Board Of Regents, The University Of Texas System |
Anti-OX40 antibodies and methods of using the same
|
GB201115280D0
(en)
|
2011-09-05 |
2011-10-19 |
Alligator Bioscience Ab |
Antibodies, uses and methods
|
RU2640913C2
(ru)
|
2011-09-07 |
2018-01-12 |
Дойчес Кребсфоршунгсцентрум |
Средства и способы лечения и/или предотвращения рака, зависимого от природного лиганда ahr
|
WO2013039954A1
(en)
|
2011-09-14 |
2013-03-21 |
Sanofi |
Anti-gitr antibodies
|
WO2013054320A1
(en)
|
2011-10-11 |
2013-04-18 |
Tel Hashomer Medical Research Infrastructure And Services Ltd. |
Antibodies to carcinoembryonic antigen-related cell adhesion molecule (ceacam)
|
PL2773671T3
(pl)
|
2011-11-04 |
2022-01-24 |
Zymeworks Inc. |
Projekt stabilnego przeciwciała heterodimerycznego z mutacjami w domenie fc
|
UY34591A
(es)
|
2012-01-26 |
2013-09-02 |
Novartis Ag |
Compuestos de imidazopirrolidinona
|
UY34632A
(es)
|
2012-02-24 |
2013-05-31 |
Novartis Ag |
Compuestos de oxazolidin- 2- ona y usos de los mismos
|
AR090263A1
(es)
|
2012-03-08 |
2014-10-29 |
Hoffmann La Roche |
Terapia combinada de anticuerpos contra el csf-1r humano y las utilizaciones de la misma
|
BR112014027244A2
(pt)
|
2012-05-15 |
2017-06-27 |
Novartis Ag |
derivados de benzamida para inibição da atividade de abl1, abl2 e bcr-abl1
|
DK2861579T5
(da)
|
2012-05-15 |
2022-10-24 |
Novartis Ag |
Benzamidderivater til at hæmme aktiviteten af ABL1, ABL2 og BCR-ABL1
|
JP6448533B2
(ja)
|
2012-05-15 |
2019-01-09 |
ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company |
Pd−1/pd−l1シグナル伝達を破壊することによる癌免疫療法
|
CA2870339C
(en)
|
2012-05-15 |
2020-06-02 |
Novartis Ag |
Compounds and compositions for inhibiting the activity of abl1, abl2 and bcr-abl1
|
AU2013261128B2
(en)
|
2012-05-15 |
2015-11-12 |
Novartis Ag |
Benzamide derivatives for inhibiting the activity of ABL1, ABL2 and BCR-ABL1
|
EP2858673A4
(en)
|
2012-06-06 |
2016-06-22 |
Oncomed Pharm Inc |
BINDING AGENTS MODULATING THE HIPPO SIGNALING PATH AND USES THEREOF
|
JO3300B1
(ar)
|
2012-06-06 |
2018-09-16 |
Novartis Ag |
مركبات وتركيبات لتعديل نشاط egfr
|
BR112014017645A2
(pt)
*
|
2012-06-21 |
2017-06-27 |
Compugen Ltd |
molécula imunológica; polinucleotídeo; vetor; célula recombinante que compreende o vetor; método para produzir molécula imunológica; anticorpo ou fragmento de ligação de antígeno do mesmo; composição farmacêutica; uso da molécula imunológica, do anticorpo, do fragmento de ligação de anticorpo ou da composição farmacêutica; método diagnóstico para diagnosticar uma doença em um indivíduo, em que a doença é selecionada do grupo que consiste em câncer, uma doença autoimune ou uma doença infecciosa; ensaio para diagnosticar uma doença em uma amostra de tecido tomada de um indivíduo; uso de um anticorpo ou um fragmento que se liga especificamente à seq id no: 10; e método diagnóstico para determinar se realiza o uso ou administra a composição
|
US10513540B2
(en)
|
2012-07-31 |
2019-12-24 |
The Brigham And Women's Hospital, Inc. |
Modulation of the immune response
|
US20140227250A1
(en)
|
2012-08-23 |
2014-08-14 |
Merck Sharp & Dohme Corp. |
Stable formulations of antibodies to tslp
|
JOP20200308A1
(ar)
*
|
2012-09-07 |
2017-06-16 |
Novartis Ag |
جزيئات إرتباط il-18
|
CA2888763A1
(en)
|
2012-10-30 |
2014-05-08 |
Apexigen, Inc. |
Anti-cd40 antibodies and methods of use
|
AU2013343425A1
(en)
|
2012-11-08 |
2015-06-11 |
Novartis Ag |
Pharmaceutical combination comprising a B-Raf inhibitor and a histone deacetylase inhibitor and their use in the treatment of proliferative diseases
|
SI2922872T1
(sl)
|
2012-11-21 |
2019-01-31 |
Janssen Biotech, Inc., |
Bispecifična protitelesa EGFR/C-MET
|
EP2925365A1
(en)
|
2012-11-28 |
2015-10-07 |
Novartis AG |
Combination therapy
|
EP2934576A1
(en)
|
2012-12-19 |
2015-10-28 |
The Johns Hopkins University |
Anti-human b7-h4 antibodies and their uses
|
AU2013372331A1
(en)
|
2013-01-10 |
2015-07-23 |
Genmab B.V. |
Human IgG1 Fc region variants and uses thereof
|
JO3519B1
(ar)
|
2013-01-25 |
2020-07-05 |
Amgen Inc |
تركيبات أجسام مضادة لأجل cdh19 و cd3
|
US9498532B2
(en)
|
2013-03-13 |
2016-11-22 |
Novartis Ag |
Antibody drug conjugates
|
US9242969B2
(en)
|
2013-03-14 |
2016-01-26 |
Novartis Ag |
Biaryl amide compounds as kinase inhibitors
|
EP3299391B1
(en)
|
2013-03-14 |
2019-12-04 |
Genentech, Inc. |
Anti-b7-h4 antibodies and immunoconjugates
|
WO2014159764A1
(en)
*
|
2013-03-14 |
2014-10-02 |
Amgen Inc. |
Chrdl-1 antigen binding proteins and methods of treatment
|
US9434719B2
(en)
|
2013-03-14 |
2016-09-06 |
Novartis Ag |
3-pyrimidin-4-yl-oxazolidin-2-ones as inhibitors of mutant IDH
|
SI2970473T1
(sl)
|
2013-03-14 |
2017-10-30 |
Bristol-Myers Squibb Company |
Kombinacija dr5 agonista in anti-pd-1 antagonista in postopek uporabe
|
EP2970980B2
(en)
|
2013-03-15 |
2022-07-27 |
Janssen Biotech, Inc. |
Manufacturing methods to control c-terminal lysine, galactose and sialic acid content in recombinant proteins
|
EP2968985A2
(en)
|
2013-03-15 |
2016-01-20 |
Amgen, Inc. |
Human antigen binding proteins that bind to proprotein convertase subtilisin kexin type 9
|
HUE040234T2
(hu)
|
2013-03-18 |
2019-02-28 |
Biocerox Prod Bv |
Humanizált anti-CD134 (OX40) antitestek és felhasználásaik
|
SG11201508528TA
(en)
|
2013-05-02 |
2015-11-27 |
Anaptysbio Inc |
Antibodies directed against programmed death-1 (pd-1)
|
WO2014183066A2
(en)
*
|
2013-05-10 |
2014-11-13 |
Whitehead Institute For Biomedical Research |
Protein modification of living cells using sortase
|
US10005839B2
(en)
|
2013-05-17 |
2018-06-26 |
Inserm (Institut National De La Sante Et De La Recherche Medicale) |
Antagonist of the BTLA/HVEM interaction for use in therapy
|
US9676853B2
(en)
|
2013-05-31 |
2017-06-13 |
Sorrento Therapeutics, Inc. |
Antigen binding proteins that bind PD-1
|
CN104250302B
(zh)
|
2013-06-26 |
2017-11-14 |
上海君实生物医药科技股份有限公司 |
抗pd‑1抗体及其应用
|
EP3021869B1
(en)
|
2013-07-16 |
2020-07-15 |
F. Hoffmann-La Roche AG |
Methods of treating cancer using pd-1 axis binding antagonists and tigit inhibitors
|
US10519238B2
(en)
|
2013-07-24 |
2019-12-31 |
Dana-Farber Cancer Institute, Inc. |
Anti-galectin-1 monoclonal antibodies and fragments thereof
|
MX2016002263A
(es)
|
2013-08-22 |
2016-12-16 |
The Council Of The Queensland Inst Of Medical Res |
Modulacion de inmunoreceptor para tratar cancer e infecciones virales.
|
US10077305B2
(en)
|
2013-09-10 |
2018-09-18 |
Medimmune Limited |
Antibodies against PD-1 and uses thereof
|
PL3702373T3
(pl)
|
2013-09-13 |
2022-12-05 |
Beigene Switzerland Gmbh |
Przeciwciała anty-PD1 i ich zastosowanie jako środki terapeutyczne i diagnostyczne
|
CN104558177B
(zh)
|
2013-10-25 |
2020-02-18 |
苏州思坦维生物技术股份有限公司 |
拮抗抑制程序性死亡受体pd-1与其配体结合的单克隆抗体及其编码序列与用途
|
SG10201804945WA
(en)
|
2013-12-12 |
2018-07-30 |
Shanghai hengrui pharmaceutical co ltd |
Pd-1 antibody, antigen-binding fragment thereof, and medical application thereof
|
DK3083694T3
(da)
|
2013-12-20 |
2024-01-29 |
Intervet Int Bv |
Caniniserede, murine anti-canin-pd-1-antistoffer
|
US9456612B2
(en)
|
2013-12-26 |
2016-10-04 |
Zimplistic Pte. Ltd. |
Dry flour dispensing apparatus and using the same for a food preparation appliance
|
CN103721255A
(zh)
*
|
2014-01-07 |
2014-04-16 |
苏州大学 |
共同阻断pd-1和tim-3信号通路在抗胃癌治疗中的用途
|
TWI680138B
(zh)
|
2014-01-23 |
2019-12-21 |
美商再生元醫藥公司 |
抗pd-l1之人類抗體
|
TWI681969B
(zh)
|
2014-01-23 |
2020-01-11 |
美商再生元醫藥公司 |
針對pd-1的人類抗體
|
JOP20200094A1
(ar)
|
2014-01-24 |
2017-06-16 |
Dana Farber Cancer Inst Inc |
جزيئات جسم مضاد لـ pd-1 واستخداماتها
|
JOP20200096A1
(ar)
|
2014-01-31 |
2017-06-16 |
Children’S Medical Center Corp |
جزيئات جسم مضاد لـ tim-3 واستخداماتها
|
US10392438B2
(en)
|
2014-05-16 |
2019-08-27 |
Pfizer Inc. |
Bispecific antibodies
|
WO2015195163A1
(en)
|
2014-06-20 |
2015-12-23 |
R-Pharm Overseas, Inc. |
Pd-l1 antagonist fully human antibody
|
TWI693232B
(zh)
|
2014-06-26 |
2020-05-11 |
美商宏觀基因股份有限公司 |
與pd-1和lag-3具有免疫反應性的共價結合的雙抗體和其使用方法
|
WO2016006241A1
(ja)
|
2014-07-09 |
2016-01-14 |
日本全薬工業株式会社 |
抗イヌpd-1抗体又は抗イヌpd-l1抗体
|
KR102524920B1
(ko)
|
2014-07-22 |
2023-04-25 |
아폴로믹스 인코포레이티드 |
항-pd-1 항체
|
US9982052B2
(en)
|
2014-08-05 |
2018-05-29 |
MabQuest, SA |
Immunological reagents
|
EP3177644B1
(en)
|
2014-08-05 |
2020-10-07 |
Mabquest SA |
Immunological reagents binding to pd-1
|
GB201419084D0
(en)
|
2014-10-27 |
2014-12-10 |
Agency Science Tech & Res |
Anti-PD-1 antibodies
|
WO2016077397A2
(en)
|
2014-11-11 |
2016-05-19 |
Sutro Biopharma, Inc. |
Anti-pd-1 antibodies, compositions comprising anti-pd-1 antibodies and methods of using anti-pd-1 antibodies
|
TWI595006B
(zh)
|
2014-12-09 |
2017-08-11 |
禮納特神經系統科學公司 |
抗pd-1抗體類和使用彼等之方法
|
DK3237446T3
(en)
|
2014-12-22 |
2021-07-26 |
Pd 1 Acquisition Group Llc |
Anti-PD-1-antistoffer
|
CN105061597B
(zh)
|
2015-06-09 |
2016-04-27 |
北京东方百泰生物科技有限公司 |
一种抗pd-1的单克隆抗体及其获得方法
|
EP3313883B1
(en)
|
2015-06-23 |
2023-12-06 |
Memorial Sloan Kettering Cancer Center |
Novel pd-1 immune modulating agents
|
BR112017027990A2
(pt)
|
2015-06-24 |
2018-08-28 |
Janssen Biotech, Inc. |
modulação imune e tratamento de tumores sólidos com anticorpos que se ligam especificamente ao cd38
|
US20170044265A1
(en)
*
|
2015-06-24 |
2017-02-16 |
Janssen Biotech, Inc. |
Immune Modulation and Treatment of Solid Tumors with Antibodies that Specifically Bind CD38
|
MX2018000621A
(es)
|
2015-07-13 |
2018-05-11 |
Cytomx Therapeutics Inc |
Anticuerpos anti-pd-1, anticuerpos anti-pd-1 activables, y metodos de uso de los mismos.
|
CN106699888B
(zh)
|
2015-07-28 |
2020-11-06 |
上海昀怡健康科技发展有限公司 |
一种pd-1抗体及其制备方法和应用
|
MX2018001227A
(es)
|
2015-07-30 |
2018-03-26 |
Macrogenics Inc |
Moleculas de union a pd-1 y metodos de uso de las mismas.
|
WO2017024465A1
(en)
|
2015-08-10 |
2017-02-16 |
Innovent Biologics (Suzhou) Co., Ltd. |
Pd-1 antibodies
|
WO2017024515A1
(en)
|
2015-08-11 |
2017-02-16 |
Wuxi Biologics (Cayman) Inc. |
Novel anti-pd-1 antibodies
|
KR102434314B1
(ko)
|
2015-09-01 |
2022-08-19 |
아게누스 인코포레이티드 |
항-pd-1 항체 및 이를 이용하는 방법
|
RU2731418C2
(ru)
|
2015-09-28 |
2020-09-02 |
Сучжоу Санкадия Биофармасьютикалз Ко., Лтд. |
Стабильный фармацевтический препарат на основе антитела к pd-1 и его применение в медицине
|
CN108368175B
(zh)
|
2015-09-29 |
2021-08-06 |
上海张江生物技术有限公司 |
Pd-1抗体及其用途
|
KR20180054824A
(ko)
|
2015-09-29 |
2018-05-24 |
셀진 코포레이션 |
Pd-1 결합 단백질 및 이의 사용 방법
|
EP3356404B1
(en)
|
2015-10-02 |
2021-08-18 |
F. Hoffmann-La Roche AG |
Anti-pd1 antibodies and methods of use
|
CR20180161A
(es)
|
2015-10-02 |
2018-05-25 |
Hoffmann La Roche |
Anticuerpos biespecíficos para pd1 y tim3
|
MX2018003936A
(es)
|
2015-10-02 |
2018-07-06 |
Symphogen As |
Anticuerpos anti proteina de muerte celular programada 1 (pd-1) y composiciones.
|
EP3150636A1
(en)
|
2015-10-02 |
2017-04-05 |
F. Hoffmann-La Roche AG |
Tetravalent multispecific antibodies
|
CN106632674B
(zh)
|
2015-10-30 |
2018-11-16 |
泽达生物医药有限公司 |
一种抗pd-1单克隆抗体、其药物组合物及其用途
|
US10894830B2
(en)
|
2015-11-03 |
2021-01-19 |
Janssen Biotech, Inc. |
Antibodies specifically binding PD-1, TIM-3 or PD-1 and TIM-3 and their uses
|
CN106699889A
(zh)
|
2015-11-18 |
2017-05-24 |
礼进生物医药科技(上海)有限公司 |
抗pd-1抗体及其治疗用途
|
WO2017087587A1
(en)
|
2015-11-18 |
2017-05-26 |
Merck Sharp & Dohme Corp. |
PD1/CTLA4 Binders
|
CA3009001A1
(en)
|
2016-01-11 |
2017-07-20 |
Universitat Zurich |
Immune-stimulating humanized monoclonal antibodies against human interleukin-2, and fusion proteins thereof
|
WO2017196847A1
(en)
|
2016-05-10 |
2017-11-16 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Variable new antigen receptor (vnar) antibodies and antibody conjugates targeting tumor and viral antigens
|
WO2017214182A1
(en)
|
2016-06-07 |
2017-12-14 |
The United States Of America. As Represented By The Secretary, Department Of Health & Human Services |
Fully human antibody targeting pdi for cancer immunotherapy
|
WO2018026248A1
(ko)
|
2016-08-05 |
2018-02-08 |
주식회사 와이바이오로직스 |
프로그램화된 세포 사멸 단백질(pd-1)에 대한 신규 항체 및 이의 용도
|
WO2018027524A1
(en)
|
2016-08-09 |
2018-02-15 |
Innovent Biologics (Suzhou) Co., Ltd. |
Pd-1 antibody formulation
|
CN106977602B
(zh)
|
2016-08-23 |
2018-09-25 |
中山康方生物医药有限公司 |
一种抗pd1单克隆抗体、其药物组合物及其用途
|
MX2019002946A
(es)
|
2016-09-14 |
2019-09-26 |
Abbvie Biotherapeutics Inc |
Anticuerpos anti-pd-1 y sus usos.
|
BR112019004995A2
(pt)
|
2016-09-14 |
2019-06-04 |
Beijing hanmi pharm co ltd |
anticorpo que se liga especificamente a pd-1 e fragmento funcional do mesmo
|
MX2019003058A
(es)
|
2016-09-21 |
2019-11-28 |
Cstone Pharmaceuticals |
Anticuerpos monoclonales novedosos para muerte programada 1 (pd-1).
|
DE102017211373A1
(de)
|
2017-07-04 |
2019-01-10 |
Continental Automotive Gmbh |
Induktive Ladevorrichtung für ein elektrisch antreibbares Kraftfahrzeug und Betriebsverfahren für die Ladevorrichtung
|