CN108379140A - A kind of composition and preparation method thereof with whitening anti-aging function - Google Patents
A kind of composition and preparation method thereof with whitening anti-aging function Download PDFInfo
- Publication number
- CN108379140A CN108379140A CN201810199937.4A CN201810199937A CN108379140A CN 108379140 A CN108379140 A CN 108379140A CN 201810199937 A CN201810199937 A CN 201810199937A CN 108379140 A CN108379140 A CN 108379140A
- Authority
- CN
- China
- Prior art keywords
- composition
- whitening
- aging function
- whitening anti
- aging
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
- A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9728—Fungi, e.g. yeasts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/85—Products or compounds obtained by fermentation, e.g. yoghurt, beer, wine
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Emergency Medicine (AREA)
- Cosmetics (AREA)
Abstract
The invention discloses a kind of compositions with whitening anti-aging function, include the following components'mass percentage：Yeast extract 3 15%, close Luo Mu leaves/stem extraction 0.5 5%, grape fermentation extract 0.5 5%, glutathione 0.02 0.5%, epigallocatechin gallate 0.5 1.0%, butanediol 10 30%, surplus is deionized water.The composition with whitening anti-aging function of the present invention is safe, quick, uses the effect for just having apparent brilliant white, microgroove reduction for one month；Yeast extract, close Luo Mu leaves/stem extraction, grape fermentation extract, glutathione, the epigallocatechin gallate contained all from being extracted in natural plants, does not stimulate safely mildly；Each component solves the problems, such as skin aging simultaneously by synergistic effect, from endogenous with external source, stimulates cell self-renewal, accelerates epidermal cell metabolism, and the approach of skin aging, self maintenance power of raising skin is blocked fundamentally to solve the problems, such as skin aging.
Description
Technical field
The invention belongs to cosmetic fields, and in particular to a kind of composition and its preparation side with whitening anti-aging function
Method and skin preparations for extenal use comprising the composition.
Background technology
As being incremented by for age, and the animation of fatigue, the grease and collagen of skin are all being lost in, flesh after 25 years old
Skin gradually loses elasticity, and the problems such as microgroove, relaxation, obscure dark yellow, pigementation occurs in face, and whitening anti-aging becomes ripe age female
The top priority of property skin care, therefore whitening anti-aging product has obtained the favor of many female friends.But it is existing in the market
The product of whitening anti-aging have the following problems：(1) slowly effect, effect unobvious；(2) there is certain irritation；(3) once not
It uses, is easy rebound, this situation why occurs, the whitening anti-aging product having its source in the market does not solve fundamentally
Certainly the problem of skin aging.
Therefore, it is necessary to safety is provided, is worked, the mild inirritative composition with whitening anti-aging function, the tool
There is the composition of whitening anti-aging function to set about from the root of skin aging and the presentation of generation, is blocked layer by layer from endogenous and external source
The effect of process of skin aging stimulates and improves itself maintenance ability of skin, is finally reached whitening anti-aging.
Invention content
The object of the present invention is to provide a kind of safety, works, stimulate mildly, it is deactivated after do not rebound it is anti-ageing with whitening
The composition of old function.
It is a further object of the present invention to provide the preparation methods of the composition with whitening anti-aging function.
It is a further object of the present invention to provide the application of the composition with whitening anti-aging function in skin care item, packets
Include toner, lotion, Essence/stoste/condensation, face cream, eye cream, essence gel, hand lotion, body frost, facial cleanser, foundation cream
Liquid, air cushion CC frosts, isolation breast and shower cream etc..
The technical solution adopted by the present invention is：A kind of composition with whitening anti-aging function, including following quality hundred
Divide the component of ratio：
Surplus is deionized water.
Preferably, the composition with whitening anti-aging function, includes the following components'mass percentage：
Surplus is deionized water.
Preferably, the composition with whitening anti-aging function, includes the following components'mass percentage：
Surplus is deionized water.
Yeast extract derives from rice wine vinasse depth ferment filtrate, rich in amino acid, small-molecular peptides, nucleotide, dimension life
Element and minerals, can activated fibroblast and horn cell, delaying skin aging effectively removes free radical, inhibits black
Element is formed, and keeps skin brilliant white penetrating.
Preferably, the one kind or two of the close Luo Mu extracts in close Luo Mu leaf extracts and Mi Luo wood stem extractions
Kind.
Close Luo Mu also known as South Africa phoenix grass are small in 24-72 by a drop water in the case where losing itself 98% moisture
When interior tax it is living newborn.The present invention extracts " bringing back to life grass " essence with high-tech means, and " life source regenerated protein group " can be excited living
Power promotes comprehensive new life of cell.
Grape fermentation extract is grape depth tunning, contains vine polyphenol and small-molecule peptide, effectively removes skin
Skin reactive oxygen species and free radicals inhibit tyrosinase, promote skin metabolism, oxidation-resisting and caducity.
Glutathione can remove exotoxin in free radical, chelating heavy metal etc., prevent cutaneous pigmentation, prevent new
Melanin forms and reduces its oxidation, to slow down aging.
Epigallocatechin gallate (EGCG) is a kind of composition extracted from Chinese green tea, is had very strong anti-oxidant
Activity, antioxidant activity are at least ascorbic more than 100 times, are 25 times of vitamin E, and cell and DNA can be protected impaired
Evil has wrinkle resistant anti-ageing, sun-proof ecchymose removing, releases heavy metallic poison, antibacterial anti-inflammatory, promote skin microcirculation, eliminate freckle, macula lutea
And other effects, keep skin smooth tender.
Preferably, it is answering for 0.2-1.0% that the composition with whitening anti-aging function, which further includes mass percent,
Close preservative.It is furthermore preferred that the composition with whitening anti-aging function further include mass percent be 0.8% it is compound
Preservative.The compound preservative is 6-10 by mass ratio:1 Phenoxyethanol and Sensiva SC50 compounds, more preferably
, the compound preservative is 9 by mass ratio:1 Phenoxyethanol and Sensiva SC50 compounds.
The present invention also provides the preparation methods of the composition with whitening anti-aging function, include the following steps：
1) yeast extract, close Luo Mu extracts, grape fermentation extract, glutathione, table Gallate are weighed by weight ratio
Catechol gallic acid ester, butanediol, compound preservative and deionized water；
2) deionized water is heated to 85 DEG C -100 DEG C, keeps the temperature 20-40min, sterilizing, cooling is added load weighted
Yeast extract, close Luo Mu extracts, grape fermentation extract, glutathione, epigallocatechin gallate, butanediol and compound
Preservative, stirring is to get to the composition with whitening anti-aging function.
Preferably, in step 2), use cooling water temperature to 45 DEG C hereinafter, stirring speed for 300-500r/min (on
This model of seamark factory, JB90-D type powerful motors blender), the time of stirring is 5-10min.
It is furthermore preferred that in step 2), deionized water is heated to 100 DEG C, keeps the temperature 30min, carries out sterilizing.
The present invention also provides a kind of skin preparations for extenal use, the skin preparations for extenal use includes the group for having whitening anti-aging function
Object is closed, wherein percentage, the composition with whitening anti-aging function accounts for the 1- of skin preparations for extenal use total weight
70%.
Preferably, the composition with whitening anti-aging function accounts for the 5-60% of skin preparations for extenal use total weight.It is more excellent
Choosing, the composition with whitening anti-aging function accounts for the 30-60% of skin preparations for extenal use total weight.
Preferably, the skin preparations for extenal use includes toner, lotion, Essence, essence stoste, essence condensation, face cream, eye
Frost, essence gel, hand lotion, body frost, facial cleanser, foundation emulsion, air cushion CC frosts, isolation breast and shower cream.
The beneficial effects of the invention are as follows：The composition with whitening anti-aging function of the present invention is safe, quick, uses
Just have within one month apparent brilliant white, microgroove reduction effect；Yeast extract, close Luo Mu leaves/stem extraction, the grape contained
Extractive from fermentative, glutathione, epigallocatechin gallate are carried from rice, Mi Luomu, grape, wheat embryo, green tea respectively
It takes, is all natural plants, mild safety does not stimulate；The composition with whitening anti-aging function by synergistic effect, from
Endogenous and external source solves the problems, such as skin aging simultaneously, stimulates cell self-renewal, accelerates epidermal cell metabolism, skin is blocked to decline
Old approach, self maintenance power of raising skin, to fundamentally solve the problems, such as skin aging.
Specific implementation mode
Embodiment 1
This is the optimization of the anti-ageing optimization component of whitening, mainly yeast extract, close Luo Mu leaves/stem extraction, grape
The each component of the optimization of extractive from fermentative, glutathione and epigallocatechin gallate component, selection is as shown in table 1.
Table 1
| Material name | Example 1 | Example 2 | Example 3 | Example 4 | Example 5 | Example 6 | Example 7 | Example 8 |
| Yeast extract | √ | √ | √ | |||||
| Astragalus Root P.E | √ | √ | √ | |||||
| Close Luo Mu leaves/stem extraction | √ | √ | √ | √ | √ | √ | ||
| Tartaric acid | √ | |||||||
| Niacinamide | √ | √ | ||||||
| Tranexamic acid | √ | √ | ||||||
| Epigallocatechin gallate | √ | √ | √ | √ | √ | √ | ||
| VC derivatives | √ | |||||||
| Grape fermentation extract | √ | √ | √ | √ | √ | |||
| Glutathione | √ | √ | √ | √ | √ | |||
| Resveratrol | √ | √ | ||||||
| Gotu Kola P.E | √ | √ | √ | √ |
Screening step and result are as follows.
(1) 1 composition of example is irritant, has allergic reaction, therefore rejects tartaric acid.
(2) 2 composition of example has unstability, meets light and heat and is easy to happen oxidation stain, therefore rejects VC derivatives.
(3) 3 composition of example will produce certain tingling sensation, and analysed composition is constituted, and rejects niacinamide.
(4) 4 composition of example will produce certain sticky sense and heavy feeling during smearing, and analyze component, reject blood coagulation
Acid.
(5) 5 composition of example tests whitening effect unobvious by personnel, by comparative analysis, rejects Gotu Kola P.E.
(6) 6 composition of example tests anti-ageing effect unobvious by personnel, by comparative analysis, rejects Astragalus Root P.E.
(7) 7 composition of example is more satisfactory by personnel's test whitening and anti-aging effect, without allergic reaction, does not become
The wild effects such as color occur, but resveratrol selling at exorbitant prices, in conjunction with cost budgeting, therefore reject resveratrol components.
(8) 8 composition of example, by optimal screening, example 8 has good whitening anti-aging effect, therefore is determined as whitening
The core component of anti-aging, and the weight percent of the addition of each component is：Yeast extract 3-15%, close Luo Mu leaves/stem
Extract 0.5-5%, grape fermentation extract 0.5-5%, glutathione 0.02-0.5%, epigallocatechin gallate 0.5-
1.0%.
Embodiment 2
This is the anti-ageing optimization for optimizing component ratio of whitening.The anti-corrosion of whitening anti-aging composition in order to further increase
The intermiscibility of property and raw material, has been added into butanediol, has optimized on the basis of embodiment 1, takes the weight percent of each component to be：
Yeast extract 5-10%, close Luo Mu leaves/stem extraction 2-4%, grape fermentation extract 2-4%, glutathione 0.05-
0.2%, epigallocatechin gallate 0.6-0.8%, butanediol 15-20%, surplus are deionized water, are further optimized each
The additive amount (weight percent) of the additive amount (weight percent) of component, each component is as shown in table 2.
Table 2
Screening step and result are as follows.
(1) yeast extract：Remaining component ratio is constant, and yeast extract takes 6%, 8%, 10% respectively, passes through comparison
Test learns that the anti-ageing effect of 10% whitening of yeast extract is most ideal.
(2) close Luo Mu leaves/stem extraction：Yeast extract 10%, other component ratios are constant, close Luo Mu leaves/stem extraction
Object takes 3.0%, 3.5%, 4.0% respectively, is learnt by contrast test result：Close Luo Mu leaves/stem extraction 3.5% and 4% is imitated
Fruit is very nearly the same, according to cost budgeting, determines close Luo Mu leaves/stem extraction 3.5%.
(3) grape fermentation extract：Yeast extract 10%, close Luo Mu leaves/stem extraction 3.5%, other component ratios
Constant, grape fermentation extract takes 2.5%, 3.0%, 3.5%, 4.0% respectively, is learnt by contrast test result：Grape is sent out
4.0% whitening effect of ferment extract is more excellent, therefore determines that grape fermentation extract ratio is 4.0%.
(4) glutathione：Yeast extract 10%, close Luo Mu leaves/stem extraction 3.5%, grape fermentation extract
4.0%, other components are constant, and glutathione takes 0.1%, 0.15% and 0.2% respectively, learn that glutathione has by experiment
Peculiar smell, therefore formula rate is preferably glutathione 0.15%.
(5) epigallocatechin gallate：Yeast extract 10%, close Luo Mu leaves/stem extraction 3.5%, grape fermentation carries
Take object 4.0%, glutathione 0.15%, other components are constant, epigallocatechin gallate takes 0.6% respectively, 0.7%,
0.8%, it is learnt by contrast test result：The anti-ageing effect of 0.8% whitening of epigallocatechin gallate is more excellent, therefore determines table Gallate
Tea phenol gallic acid ester ratio is 0.8%.
Therefore the anti-ageing composition optimum weight percentage proportioning of whitening is：Yeast extract 10%, close Luo Mu leaves/stem extraction
3.5%, grape fermentation extract 4%, glutathione 0.15%, epigallocatechin gallate 0.8% and butanediol 20%.
Embodiment 3
A kind of composition with whitening anti-aging function, includes the following components'mass percentage：
Surplus is deionized water.
The preparation method of composition with whitening anti-aging function, includes the following steps：
1) weigh by weight ratio yeast extract, close Luo Mu leaves/stem extraction, grape fermentation extract, glutathione,
Epigallocatechin gallate, butanediol, compound preservative and deionized water；
2) deionized water is heated to 85 DEG C DEG C, keeps the temperature 20min, sterilizing, load weighted yeast extraction is added in cooling
Object, close Luo Mu leaves/stem extraction, grape fermentation extract, glutathione, epigallocatechin gallate, butanediol and compound anti-
Rotten agent, with speed 300r/min stirring 10min to get to the composition with whitening anti-aging function.
Embodiment 4
A kind of composition with whitening anti-aging function, includes the following components'mass percentage：
Surplus is deionized water.
The preparation method of composition with whitening anti-aging function, includes the following steps：
1) weigh by weight ratio yeast extract, close Luo Mu leaves/stem extraction, grape fermentation extract, glutathione,
Epigallocatechin gallate, butanediol, compound preservative and deionized water；
2) deionized water is heated to 90 DEG C, keeps the temperature 30min, sterilizing, load weighted yeast extraction is added in cooling
Object, close Luo Mu leaves/stem extraction, grape fermentation extract, glutathione, epigallocatechin gallate, butanediol and compound anti-
Rotten agent, with speed 500r/min stirring 5min to get to the composition with whitening anti-aging function.
Embodiment 5
This is the toner of the anti-ageing composition of whitening preferably gone out containing embodiment 2, the dosage quality hundred of each substance
Fraction representation, as shown in table 3.
The component of toner of the table 3 containing the anti-ageing composition of whitening
Preparation method includes the following steps：(1) by isoprene, glycerin polyether -26, PCA-2Na, glycine betaine, PEG-400
It is add to deionized water, Sodium Hyaluronate is also added in deionized water after being disperseed with butanediol, stirs, and is mixed
Close object A phases；(2) it by A phases heating water bath to 85 DEG C, is allowed to fully dissolve, heat preservation 30min disinfections use cooling water temperature after disinfection；
(3) A phases are cooled to 45 DEG C hereinafter, the anti-ageing composition of addition whitening, tremella polysaccharides, essence and compound preservative, are sufficiently stirred
15min is allowed to fully dissolve, and then stops stirring to get to the toner containing the anti-ageing composition of whitening.
Test the using effect of the toner of the composition containing the whitening anti-aging.
Tested crowd：80 35-50 Sui female volunteers divide 8 groups, and every group of 10 people, normal, drying and sensitive skin are equal
Have；Test method：After subject cleans face, the toner prepared respectively using the present invention using 1 month, is used 2 times a day
Skin surface analysis instrument observes skin smoothness, wrinkle depth, skin shine, and observes and records the effect used.
It is obtained by analysis of experimental data, when adding proportion of the anti-ageing composition of whitening in toner is 45% (weight
Than) when, there is the anti-ageing effect of apparent whitening, the experimental data of collection is as shown in table 4-7.
4 wrinkle test result of table
| Wrinkle decrease rate | 20% or more | 15-20% | 10-15% | 10% or less |
| Number | 45 | 25 | 8 | 2 |
5 skin roughness test result of table
6 skin shine test result of table
7 dermal melanin test result of table
Embodiment 6
This is the Essence of the anti-ageing composition of whitening preferably gone out containing embodiment 2, the dosage quality hundred of each substance
Fraction representation, as shown in table 8.
The component of Essence of the table 8 containing the anti-ageing composition of whitening
Preparation method includes the following steps：(1) glycerine, propylene glycol, allantoin, glycine betaine are add to deionized water,
Then xanthans and Sodium Hyaluronate are also added in deionized water after being uniformly dispersed with butanediol, stir, and are mixed
Close object A phases；(2) carbomer is dispersed in mixture A, impregnates 15 minutes, stirs evenly and be allowed to fully dissolve, mixed
Close object B phases；(3) mixture B phases are heated to 85 DEG C while stirring, are allowed to fully dissolve, heat preservation 30min disinfections are used after disinfection
Cooling water temperature；(4) 45 DEG C are cooled to hereinafter, triethanolamine, the anti-ageing composition of whitening, tremella polysaccharides and composite anti-corrosive is added
Agent is sufficiently stirred 15min, is allowed to be sufficiently mixed, and then stops stirring to get to the Essence containing the anti-ageing composition of whitening.
Test the using effect of the Essence of the composition containing the whitening anti-aging.
Tested crowd：80 35-50 Sui female volunteers divide 8 groups, and every group of 10 people, normal, drying and sensitive skin are equal
Have；Test method：After subject cleans face, the Essence prepared respectively using the present invention using 1 month, is used 2 times a day
Skin surface analysis instrument observes skin smoothness, wrinkle depth, skin shine, and observes and records the effect used.
It is obtained by analysis of experimental data, when adding proportion of the anti-ageing composition of whitening in Essence is 50% (weight
Than) when, there is the anti-ageing effect of apparent whitening, the experimental data of collection is as shown in table 9-12.
9 wrinkle test result of table
| Wrinkle decrease rate | 20% or more | 15-20% | 10-15% | 10% or less |
| Number | 43 | 28 | 7 | 2 |
10 skin roughness test result of table
11 skin shine test result of table
12 dermal melanin test result of table
Embodiment 7
This is the lotion of the anti-ageing composition of whitening preferably gone out containing embodiment 2, the dosage quality percentage of each substance
Number expression, as shown in table 13.
The component of lotion of the table 13 containing the anti-ageing composition of whitening
Preparation method includes the following steps：(1) propylene glycol, allantoin, glycine betaine, panthenol, EDTA-2Na are added to
In ionized water, then xanthans and Sodium Hyaluronate are also added in deionized water after being uniformly dispersed with glycerine, are heated with stirring to 85
DEG C, heat preservation disinfection 30min obtains mixture A phases；(2) by saualane, caprylic/capric triglyceride, DC-345, poly dimethyl
Siloxanes, cetostearyl alcohol, tocopherol (vitamin E) are uniformly mixed, and are then heated to 85 DEG C, heat preservation disinfection 15min is mixed
Close object B phases；(3) under stirring, mixture B is added in A phases, high speed homogenization 6min, homogeneous speed is 2000r/
Min-4000r/min (determines) according to homogeneous acc power, and SEPIPLUS TM 400 are added after high speed homogenization, and then appropriateness is equal again
Matter 50 seconds, stirring and emulsifying 15min are then turned on cooling water temperature；(4) be cooled to 45 DEG C hereinafter, be added the anti-ageing composition of whitening,
Tremella polysaccharides, compound preservative and essence, are sufficiently stirred 15min, are allowed to be sufficiently mixed, then stop stirring to get to containing
The lotion of the anti-ageing composition of whitening.
Test the using effect of the lotion of the composition containing the whitening anti-aging.
Tested crowd：80 35-50 Sui female volunteers divide 8 groups, and every group of 10 people, normal, drying and sensitive skin are equal
Have；Test method：After subject cleans face, the lotion prepared respectively using the present invention using 1 month, uses skin 2 times a day
Skin surface analyzer observes skin smoothness, wrinkle depth, skin shine, and observes and records the effect used.
It is obtained by analysis of experimental data, when adding proportion of the anti-ageing composition of whitening in lotion is 55% (weight ratio)
When, there is the anti-ageing effect of apparent whitening, the experimental data of collection is as shown in table 14-17.
14 wrinkle test result of table
| Wrinkle decrease rate | 20% or more | 15-20% | 10-15% | 10% or less |
| Number | 42 | 28 | 8 | 2 |
15 skin roughness test result of table
16 skin shine test result of table
17 dermal melanin test result of table
Embodiment 8
This is the eye cream of the anti-ageing composition of whitening preferably gone out containing embodiment 2, the dosage quality percentage of each substance
Number expression, as shown in table 18.
The component of eye cream of the table 18 containing the anti-ageing composition of whitening
Preparation method includes the following steps：(1) propylene glycol, allantoin, glycine betaine, panthenol, EDTA-2Na are added to
In ionized water, then xanthans and Sodium Hyaluronate are also added in deionized water after being uniformly dispersed with glycerine, are heated with stirring to 85
DEG C, heat preservation disinfection 30min obtains mixture A phases；(2) by saualane, caprylic/capric triglyceride, DC-345, poly dimethyl
Siloxanes, cetostearyl alcohol, tocopherol (vitamin E), wheat-germ oil are uniformly mixed, and are then heated to 85 DEG C, heat preservation disinfection
15min obtains mixture B phases；(3) under stirring, mixture B is added in A phases, high speed homogenization 6min, homogeneous speed
Degree is 2000r/min-4000r/min (being determined according to homogeneous acc power), SEPIPLUS TM400 is added after high speed homogenization, then
Appropriate homogeneous 50 seconds again, stirring and emulsifying 15min is then turned on cooling water temperature；(4) 45 DEG C are cooled to hereinafter, whitening is added to resist
Decline composition, tremella polysaccharides, compound preservative and essence, is sufficiently stirred 15min, is allowed to be sufficiently mixed, and then stops stirring, i.e.,
Obtain the eye cream containing the anti-ageing composition of whitening.
Test the using effect of the eye cream of the composition containing the whitening anti-aging.
Tested crowd：80 35-50 Sui female volunteers divide 8 groups, and every group of 10 people, normal, drying and sensitive skin are equal
Have；Test method：After subject cleans face, the eye cream prepared respectively using the present invention is applied to circumference of eyes, 2 times a day,
Using 1 month, the smoothness of eye part skin, wrinkle depth, skin shine are observed with skin surface analysis instrument, and observe and record
The effect used.
It is obtained by analysis of experimental data, when adding proportion of the anti-ageing composition of whitening in eye cream is 60% (weight ratio)
When, there is the anti-ageing effect of apparent whitening, the experimental data of collection is as shown in table 19-22.
19 wrinkle test result of table
| Eye wrinkle-removing slip | 20% or more | 15-20% | 10-15% | 10% or less |
| Number | 52 | 24 | 3 | 1 |
20 skin roughness test result of table
21 skin shine test result of table
22 dermal melanin test result of table
By above-mentioned analysis it is found that the anti-ageing composition of whitening prepared by the present invention has excellent whitening anti-aging function, peace
Entirely, non-stimulated, the anti-ageing composition of the whitening can also be made an addition to toner, lotion, Essence/stoste/condensation, face cream, eye
In frost, essence gel, hand lotion, body frost, facial cleanser, foundation emulsion, air cushion CC frosts, isolation breast and shower cream.
The above embodiment is a preferred embodiment of the present invention, but embodiments of the present invention are not by above-described embodiment
Limitation, others are any should all without departing from the change made under spirit and principles of the present invention, modification, replacement, combination and simplification
For equivalent substitute mode, it is included in protection scope of the present invention.
Claims (10)
1. a kind of composition with whitening anti-aging function, which is characterized in that include the following components'mass percentage：
2. the composition according to claim 1 with whitening anti-aging function, which is characterized in that including following quality hundred
Divide the component of ratio：
3. the composition according to claim 1 with whitening anti-aging function, which is characterized in that including following quality hundred
Divide the component of ratio：
4. the composition according to any one of claim 1-3 with whitening anti-aging function, which is characterized in that described
Close Luo Mu extracts are selected from one or both of close Luo Mu leaf extracts and Mi Luo wood stem extractions.
5. the composition according to any one of claim 1-3 with whitening anti-aging function, which is characterized in that described
Composition with whitening anti-aging function further includes the compound preservative that mass percent is 0.2-1.0%, described compound anti-
Rotten agent is 6-10 by mass ratio:1 Phenoxyethanol and Sensiva SC50 compounds.
6. the preparation method of the composition with whitening anti-aging function described in any one of claim 1-5, feature exist
In including the following steps：
1) yeast extract, close Luo Mu extracts, grape fermentation extract, glutathione, table Gallate catechu are weighed by weight ratio
Phenol gallic acid ester, butanediol, compound preservative and deionized water；
2) deionized water is heated to 85 DEG C -100 DEG C, keeps the temperature 20-40min, sterilizing, load weighted yeast is added in cooling
Extract, close Luo Mu extracts, grape fermentation extract, glutathione, epigallocatechin gallate, butanediol and composite anti-corrosive
Agent, stirring is to get to the composition with whitening anti-aging function.
7. preparation method according to claim 6, which is characterized in that in step 2), use cooling water temperature to 45 DEG C with
Under, the speed of stirring is 300-500r/min, and the time of stirring is 5-10min.
8. a kind of skin preparations for extenal use, which is characterized in that the skin preparations for extenal use includes the tool described in any one of claim 1-5
There are the composition of whitening anti-aging function, wherein percentage, the composition with whitening anti-aging function to account for
The 1-70% of skin preparations for extenal use total weight.
9. skin preparations for extenal use according to claim 8, which is characterized in that the composition with whitening anti-aging function
Account for the 5-60% of skin preparations for extenal use total weight.
10. skin preparations for extenal use according to claim 8 or claim 9, which is characterized in that the skin preparations for extenal use include toner,
Lotion, Essence, essence stoste, essence condensation, face cream, eye cream, essence gel, hand lotion, body frost, facial cleanser, foundation emulsion,
Air cushion CC frosts, isolation breast and shower cream.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810199937.4A CN108379140B (en) | 2018-03-12 | 2018-03-12 | Composition with whitening and anti-aging functions and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810199937.4A CN108379140B (en) | 2018-03-12 | 2018-03-12 | Composition with whitening and anti-aging functions and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN108379140A true CN108379140A (en) | 2018-08-10 |
| CN108379140B CN108379140B (en) | 2021-06-04 |
Family
ID=63067433
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810199937.4A Active CN108379140B (en) | 2018-03-12 | 2018-03-12 | Composition with whitening and anti-aging functions and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN108379140B (en) |
Cited By (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109044929A (en) * | 2018-09-14 | 2018-12-21 | 江苏魅莉萱言生物科技有限公司 | A kind of surfactant with moisturizing, anti-aging and whitening spot-removing function |
| CN109350564A (en) * | 2018-11-02 | 2019-02-19 | 广州丽彦妆生物科技有限公司 | A kind of resurrection is careless to repair stoste and preparation method thereof |
| CN110200878A (en) * | 2019-07-19 | 2019-09-06 | 珠海海狮龙生物科技有限公司 | A kind of whitening spot-removing skin care item |
| CN110464672A (en) * | 2019-09-09 | 2019-11-19 | 上海新高姿化妆品有限公司 | A kind of cosmetic composition with safe antioxidant effect |
| CN110623885A (en) * | 2019-10-28 | 2019-12-31 | 北京皓尔生物科技有限公司 | Anti-glycosylation yellow-dispelling and anti-aging composition and preparation method and application thereof |
| CN110664641A (en) * | 2019-10-21 | 2020-01-10 | 刘艳 | A cosmetic material epigallocatechin gallate glucoside |
| CN111265454A (en) * | 2020-04-10 | 2020-06-12 | 上海新高姿化妆品有限公司 | Moisture-preserving and water-replenishing anti-aging cosmetic composition |
| CN111329810A (en) * | 2020-04-10 | 2020-06-26 | 上海新高姿化妆品有限公司 | Antioxidant anti-aging cosmetic composition |
| CN112716839A (en) * | 2020-12-23 | 2021-04-30 | 上海林清轩生物科技有限公司 | Composition for resisting oxidation and repairing oxidative damage and application thereof |
| CN113599310A (en) * | 2021-09-18 | 2021-11-05 | 上海新高姿化妆品有限公司 | Moisturizing composition and application thereof in cosmetics |
| CN113876675A (en) * | 2021-10-20 | 2022-01-04 | 广州市澳源科技集团有限公司 | Fermented composition containing purple rice grape component and preparation method thereof |
| CN114652654A (en) * | 2021-04-19 | 2022-06-24 | 上海康美国际生化有限公司 | Mild non-irritant moisturizing and whitening composition and preparation method thereof |
| CN115569080A (en) * | 2022-09-16 | 2023-01-06 | 福州首创生物医药科技有限公司 | Acne-removing composition, application thereof, curcumin acne-removing essence gel and preparation method |
| CN116421494A (en) * | 2023-03-03 | 2023-07-14 | 广州栋方生物科技股份有限公司 | Application of combination of carnosine zinc and glutathione zinc in whitening and/or anti-aging |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002020300A (en) * | 2000-07-07 | 2002-01-23 | Ichimaru Pharcos Co Ltd | Cosmetic composition |
| CN1927164A (en) * | 2006-08-21 | 2007-03-14 | 浙江大学 | Skin antisenescence formulation containing catechin |
| FR2997853A1 (en) * | 2012-11-09 | 2014-05-16 | Oreal | Reducing or delaying the thinning of skin and the sagging of skin and stimulating cellular metabolism of keratinocytes, comprises applying effective quantity of an extract of Myrothamnus flabellifolia to skin |
| CN105055296A (en) * | 2015-08-21 | 2015-11-18 | 广州透真生物科技有限公司 | Skin care product composition containing saccharomycetes fermentation product filter liquor |
-
2018
- 2018-03-12 CN CN201810199937.4A patent/CN108379140B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002020300A (en) * | 2000-07-07 | 2002-01-23 | Ichimaru Pharcos Co Ltd | Cosmetic composition |
| CN1927164A (en) * | 2006-08-21 | 2007-03-14 | 浙江大学 | Skin antisenescence formulation containing catechin |
| FR2997853A1 (en) * | 2012-11-09 | 2014-05-16 | Oreal | Reducing or delaying the thinning of skin and the sagging of skin and stimulating cellular metabolism of keratinocytes, comprises applying effective quantity of an extract of Myrothamnus flabellifolia to skin |
| CN105055296A (en) * | 2015-08-21 | 2015-11-18 | 广州透真生物科技有限公司 | Skin care product composition containing saccharomycetes fermentation product filter liquor |
Non-Patent Citations (1)
| Title |
|---|
| (株)澳斯考丽亚: "Clapiel抗皱保湿安瓶", 《科妆网》 * |
Cited By (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109044929A (en) * | 2018-09-14 | 2018-12-21 | 江苏魅莉萱言生物科技有限公司 | A kind of surfactant with moisturizing, anti-aging and whitening spot-removing function |
| CN109350564A (en) * | 2018-11-02 | 2019-02-19 | 广州丽彦妆生物科技有限公司 | A kind of resurrection is careless to repair stoste and preparation method thereof |
| CN110200878A (en) * | 2019-07-19 | 2019-09-06 | 珠海海狮龙生物科技有限公司 | A kind of whitening spot-removing skin care item |
| CN110464672A (en) * | 2019-09-09 | 2019-11-19 | 上海新高姿化妆品有限公司 | A kind of cosmetic composition with safe antioxidant effect |
| CN110664641A (en) * | 2019-10-21 | 2020-01-10 | 刘艳 | A cosmetic material epigallocatechin gallate glucoside |
| CN110623885A (en) * | 2019-10-28 | 2019-12-31 | 北京皓尔生物科技有限公司 | Anti-glycosylation yellow-dispelling and anti-aging composition and preparation method and application thereof |
| CN111329810B (en) * | 2020-04-10 | 2022-10-18 | 上海新高姿化妆品有限公司 | Antioxidant anti-aging cosmetic composition |
| CN111329810A (en) * | 2020-04-10 | 2020-06-26 | 上海新高姿化妆品有限公司 | Antioxidant anti-aging cosmetic composition |
| CN111265454A (en) * | 2020-04-10 | 2020-06-12 | 上海新高姿化妆品有限公司 | Moisture-preserving and water-replenishing anti-aging cosmetic composition |
| CN112716839A (en) * | 2020-12-23 | 2021-04-30 | 上海林清轩生物科技有限公司 | Composition for resisting oxidation and repairing oxidative damage and application thereof |
| CN112716839B (en) * | 2020-12-23 | 2023-01-03 | 上海林清轩生物科技有限公司 | Composition for resisting oxidation and repairing oxidative damage and application thereof |
| CN114652654A (en) * | 2021-04-19 | 2022-06-24 | 上海康美国际生化有限公司 | Mild non-irritant moisturizing and whitening composition and preparation method thereof |
| CN113599310A (en) * | 2021-09-18 | 2021-11-05 | 上海新高姿化妆品有限公司 | Moisturizing composition and application thereof in cosmetics |
| CN113599310B (en) * | 2021-09-18 | 2023-02-10 | 上海新高姿化妆品有限公司 | Moisturizing composition and application thereof in cosmetics |
| CN113876675A (en) * | 2021-10-20 | 2022-01-04 | 广州市澳源科技集团有限公司 | Fermented composition containing purple rice grape component and preparation method thereof |
| CN115569080A (en) * | 2022-09-16 | 2023-01-06 | 福州首创生物医药科技有限公司 | Acne-removing composition, application thereof, curcumin acne-removing essence gel and preparation method |
| CN115569080B (en) * | 2022-09-16 | 2023-10-20 | 福州首创生物医药科技有限公司 | Acne-removing composition and application thereof, curcumin acne-removing essence gel and preparation method |
| CN116421494A (en) * | 2023-03-03 | 2023-07-14 | 广州栋方生物科技股份有限公司 | Application of combination of carnosine zinc and glutathione zinc in whitening and/or anti-aging |
Also Published As
| Publication number | Publication date |
|---|---|
| CN108379140B (en) | 2021-06-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN108379140A (en) | A kind of composition and preparation method thereof with whitening anti-aging function | |
| CN111317701B (en) | Skin barrier repair compound, skin care emulsion and preparation method thereof | |
| US8808761B2 (en) | Composition of skin external application containing rose extract and epigallocatechin gallate(EGCG) | |
| CN105168054A (en) | Mask capable of supplementing water, whitening and removing wrinkles and preparation method of mask | |
| CN107898660A (en) | A kind of tender skin water light stoste and its preparation method and application | |
| CN111297788A (en) | Whitening and spot-fading essence and preparation method thereof | |
| CN107049912A (en) | Lightening compositions and its application containing green tea fermentation filtrate | |
| CN111135112A (en) | Wrinkle-removing anti-aging skin care composition and application thereof | |
| CN113288822A (en) | Multi-dimensional anti-wrinkle composition, cosmetic composition and preparation method of cosmetic composition | |
| CN109939064A (en) | The Essence of the metabolite containing probiotics fermention and its application in cosmetics | |
| CN114099387B (en) | Rose whitening and moisturizing essence emulsion and preparation method thereof | |
| CN105287282B (en) | A kind of chocolate lees nutritional mask and preparation method thereof | |
| CN109528536A (en) | A kind of skin care item and preparation method thereof containing choline ellagic acid salt | |
| CN116211783B (en) | Cosmetic composition containing dendrobium candidum extract and preparation method and application thereof | |
| CN109260086B (en) | Anti-wrinkle essence, preparation method and application thereof | |
| CN115607476B (en) | Composition with moisturizing and antioxidation effects and application thereof | |
| CN116327674A (en) | Anti-wrinkle compact micro-nano essence emulsion and preparation method thereof | |
| CN108354894A (en) | A kind of sensitive flesh skin composition of efficient absorption and preparation method thereof | |
| WO2014167557A1 (en) | Cosmetic topical skin treatment formulation | |
| CN113425611A (en) | Anti-aging composition for four-dimensional tissue repair through teprenone and application thereof | |
| CN113368003A (en) | Composition with overnight muscle repairing effect and preparation method and application thereof | |
| CN112220724A (en) | Plant composition and preparation method and application thereof | |
| CN114903812A (en) | Special-moistening repair cream and preparation method thereof | |
| CN110339148A (en) | The anti-ageing low sensitization composition of whitening and the anti-ageing low sensitization facial mask of whitening and preparation method | |
| CN110755343A (en) | Emulsion for old people and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |