CN112220724A

CN112220724A - Plant composition and preparation method and application thereof

Info

Publication number: CN112220724A
Application number: CN202011019791.4A
Authority: CN
Inventors: 王律徉
Original assignee: Guangzhou Meiwu Biotechnology Co Ltd
Current assignee: Guangzhou Meiwu Biotechnology Co Ltd
Priority date: 2020-09-24
Filing date: 2020-09-24
Publication date: 2021-01-15

Abstract

The invention discloses a composition, a preparation method and application thereof, and belongs to the technical field of daily cosmetics. The botanical composition of the invention comprises a eriodictyon rhodiola root extract, a kiwi fruit extract, a bistort rhizome extract, a ophiopogon root tuber extract and a maca root extract. The body lotion prepared from the plant composition is safe and non-irritant to skin, has good moisturizing, whitening and antibacterial properties, and can keep a stable state for a long time. In addition, the preparation method of the body lotion is simple, requires less equipment and is suitable for industrial production.

Description

Plant composition and preparation method and application thereof

Technical Field

The invention belongs to the technical field of daily cosmetics, and particularly relates to a plant composition and a preparation method and application thereof.

Background

Skin care emulsion cosmetics are used for the purpose of retaining a proper amount of water in the skin, particularly in the outermost horny layer of the skin. It can not only keep skin moisture balance, but also supplement oily components and hydrophilic moisture keeping components, and can be used as active ingredient and carrier of medicament for skin absorption. With the improvement of living standard and increasing demand, people have higher and higher requirements on skin care products, and meanwhile, the efficacy and the practicability in the products are more emphasized.

However, the existing products are often difficult to have multiple effects at the same time, the difficulty that raw materials which need to achieve different effects are added into the same system in a compounding manner and are stably stored is greatly increased due to the characteristics, properties and other product reasons, in addition, the raw materials adopted by some products on the market are greatly harmful to human bodies, cannot achieve better effect, and can cause skin allergy and other conditions.

Disclosure of Invention

The invention aims to overcome the defects of the prior art and provides a plant composition capable of keeping moisture and moistening skin for a long time, and a preparation method and application thereof.

In order to achieve the purpose, the technical scheme adopted by the invention is as follows: a botanical composition comprising eriodictyon root extract, kiwi fruit extract, bistort rhizome extract, ophiopogon root tuber extract, and maca root extract.

The rhodiola sacra root extract contains phenolic acid compounds, flavone compounds and arbutin components, can promote the combination of hemoglobin and oxygen of a human body, has the effect of activating blood, can eliminate superoxide radical, has the effect of inhibiting tyrosinase and hyaluronidase, can enable the skin to be more ruddy, has the effects of moisturizing and whitening, and in addition, the rhodiola sacra has a good antibacterial effect and can protect cells with damaged skin.

The kiwi fruit extract contains flavonoid compounds, saponin compounds, steroid compounds, alpha-linolenic acid, linoleic acid and other components and rich vitamin C, can supplement nutrients to skin, remove excessive cuticle, prevent or lighten black spots, inhibit hyaluronidase activity, promote epidermal cell proliferation, make skin more white and fine, and improve the problem of large pores.

The rhizoma Bistortae extract contains phenolic acid compounds, triterpenoid saponins, flavonoids, beta-sitosterol and the like, has good antibacterial property, can be used for treating pox muscles, has the effect of reducing swelling, can eliminate free radicals and inhibit the activity of neuraminidase, and has the effect of whitening.

The radix ophiopogonis tuber extract contains steroidal saponins, homoisoflavonoids, beta-sitosterol, stigmasterol, borneol glycoside, aristolochic acid and other components, can eliminate free radicals, has an anti-aging effect, has a promoting effect on arginase activity, is beneficial to preventing and treating dry skin, has a proliferation effect on epidermal fibroblasts, can promote cell metabolism, has a certain inhibiting effect on tyrosinase, and can whiten the skin.

The maca root extract contains linolenic acid, linoleic acid, phytosterol and other components, can eliminate free radicals, has a good anti-aging effect, can promote the generation of collagen, is suitable for skin with vitality deficiency and dull color, and can improve the skin firmness and luster.

Preferably, the plant composition comprises the following ingredients in parts by weight: 10-20 parts of eriodictyon rhodiola root extract, 5-15 parts of kiwi fruit extract, 12-20 parts of bistort rhizome extract, 20-35 parts of radix ophiopogonis tuber extract and 20-35 parts of maca root extract.

The applicant of the invention verifies through multiple experiments that the plant composition in the body milk has better moisturizing, skin moistening and whitening effects after being compounded according to the proportion, and is effective for a long time and good in stability.

Preferably, the plant composition comprises the following ingredients in parts by weight: 17 parts of radix eriodictyon extract, 10 parts of kiwi fruit extract, 18 parts of bistort rhizome extract, 25 parts of radix ophiopogonis root tuber extract and 30 parts of maca root extract.

Furthermore, the present invention discloses the use of the plant composition in a body milk comprising an aqueous phase and an oil phase, the aqueous phase comprising the plant composition.

Preferably, the aqueous phase further comprises one or more of an emulsifier, a thickener, a chelating agent, a preservative, a fragrance, a pH adjuster; the oil phase comprises one or more of a humectant, an antioxidant and a film forming agent.

Preferably, the emulsifier is glyceryl stearate/PEG-100 stearate; the thickening agent is acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer; the pH regulator is triethanolamine; the oil phase comprises isopropyl myristate, squalane, shea butter, glycerol, tocopherol, and coconut oil.

Preferably, the body milk comprises the following components in percentage by mass: 0.5-2% of glyceryl stearate/PEG-100 stearate, 0.1-0.5% of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, 0.1-0.5% of triethanolamine, 0.05-0.2% of chelating agent, 0.1-1% of preservative, 0.5-1% of essence, 1-5% of plant composition, 1-10% of isopropyl myristate, 1-15% of squalane, 1-15% of shea butter, 1-5% of glycerol, 0.5-1.5% of tocopherol and 1-5% of coconut oil.

In addition, the invention discloses a preparation method of the plant composition, which comprises the following steps: screening, washing, drying and grinding plant raw materials to obtain powder, then carrying out reflux extraction for 4-6 times by using alcohol with the volume fraction of 50% of ethanol, wherein each time is 30-90min to obtain an extract, and drying the extract after atmospheric concentration to obtain the plant composition.

Meanwhile, the invention discloses a preparation method of the body lotion, which comprises the following steps:

(1) adding the oil phase raw materials into an emulsifying pot, heating to 70-90 ℃ to dissolve the oil phase raw materials, and uniformly stirring to obtain a mixed solution A;

(2) adding glyceryl stearate/PEG-100 stearate, acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer and chelating agent into water, heating to 70-80 deg.C for dissolving, and stirring to obtain mixed solution B;

(3) adding the mixed solution A into the mixed solution B, and emulsifying at 60-75 ℃ at the stirring speed of 1200-2500rpm for 20-50min to obtain an emulsion;

(4) adding triethanolamine to adjust pH under stirring, and continuously stirring;

(5) and (3) when the emulsion is cooled to 30-50 ℃, adding the preservative, the essence and the plant composition, and uniformly stirring to obtain the body lotion.

Compared with the prior art, the invention has the beneficial effects that: according to the invention, by analyzing the components of various plant extracts, adjusting the proportion and the preparation process, the body lotion with long-acting moisturizing effect, skin moistening effect and whitening effect is finally prepared, and the body lotion can meet the pursuit of people to the characteristics of body lotion such as functionality, lasting effect, no stimulation, safety and the like.

Detailed Description

To better illustrate the objects, technical solutions and advantages of the present invention, the present invention will be further described with reference to specific examples (unless otherwise specified, the amounts used in the examples and comparative examples of the present invention are in parts by weight, and the total weight of each example and comparative example is the same).

Example 1

In an embodiment of the body lotion of the present invention, the formula of the body lotion of this embodiment is as follows (100 parts by weight in total):

the body lotion of this example was prepared from 1 part glyceryl stearate/PEG-100 stearate, 0.15 part acrylic acid/C10-30 alkanol acrylate crosspolymer, 0.15 part triethanolamine, 0.1 part chelating agent, 0.5 part preservative, 0.75 part fragrance, 3 parts botanical composition, 5 parts isopropyl myristate, 10 parts squalane, 8 parts shea butter, 3 parts glycerin, 1 part tocopherol, 3 parts coconut oil, and 64.35 parts water, the formulation of which is shown in Table 1.

The preparation method of the body lotion described in this example is as follows:

(1) screening, washing, drying and grinding plant raw materials for preparing the plant composition to obtain powder, then carrying out reflux extraction for 5 times and 45min each time by using alcohol with the volume fraction of 50% to obtain an extract, and drying the extract after concentrating the extract at normal pressure to obtain the plant composition.

(2) Adding isopropyl myristate, squalane, shea butter, glycerol, tocopherol and coconut oil into an emulsifying pot, heating to 80 ℃ to dissolve, and uniformly stirring to obtain a mixed solution A;

(3) adding glyceryl stearic acid/PEG-100 stearate, acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer and chelating agent into water, heating to 75 ℃ to dissolve, and stirring uniformly to obtain a mixed solution B;

(4) mixing the mixed solution A and the mixed solution B together, stirring at the rotating speed of 2000rpm at the temperature of 70 ℃, and emulsifying for 30min to obtain an emulsion;

(5) adding triethanolamine to adjust pH under stirring, and continuously stirring;

(6) and (3) when the emulsion is cooled to 45 ℃, adding the preservative, the essence and the plant composition, and uniformly stirring to obtain the body lotion.

Example 2

An embodiment of the body lotion of the present invention is the same as that of embodiment 1 except that the formula of the plant composition is different from that of embodiment 1, and the formula of the plant composition is shown in table 1.

Example 3

Example 4

the body lotion of this example was prepared from 0.5 parts glyceryl stearate/PEG-100 stearate, 0.5 parts acrylic/C10-30 alkanol acrylate crosspolymer, 0.5 parts triethanolamine, 0.05 parts chelating agent, 0.1 parts preservative, 0.5 parts fragrance, 1 part botanical composition, 1 part isopropyl myristate, 15 parts squalane, 1 part shea butter, 5 parts glycerin, 0.5 parts tocopherol, 1 part coconut oil, and 73.35 parts water, the formulation of which is shown in Table 1.

The body lotion described in this example was prepared in the same manner as in example 1.

Example 5

the body lotion of this example was prepared from 2 parts glyceryl stearate/PEG-100 stearate, 0.1 part acrylic acid/C10-30 alkanol acrylate crosspolymer, 0.1 part triethanolamine, 0.2 part chelating agent, 1 part preservative, 1 part perfume, 5 parts botanical composition, 10 parts isopropyl myristate, 1 part squalane, 15 parts shea butter, 1 part glycerin, 1.5 parts tocopherol, 5 parts coconut oil and 57.1 parts water, the formulation of which is shown in Table 1.

Comparative example 1

The formulation of the plant composition of the body lotion is different from that of the invention, the specific formulation is shown in table 1, and the formulation and preparation method of other components are the same as those of the embodiment 1.

Comparative example 2

Comparative example 3

Comparative example 4

Comparative example 5

TABLE 1 plant composition recipe (parts by weight)

Performance testing

1) Safety test

Human skin patch tests were performed on examples 1 to 5 with reference to "cosmetic hygiene standards". 150 healthy, allergy-free volunteers 18-60 years old were selected as subjects, which were divided into 5 groups of 30 persons each, and no other skin care products were used during the trial. Selecting a spot tester with an area of 6mm multiplied by 6mm, putting a test object into a small chamber of the spot tester, wherein the dosage is 0.025g, sticking the spot tester with the test object on the back of a subject by using a hypoallergenic adhesive tape, and lightly pressing the spot tester with a palm to uniformly stick the spot tester on the skin for 24 hours. The skin reactions were observed at 30min (after the indentation disappeared), 24h, and 48h after the test article plaque removal, respectively, according to the standards shown in table 2, and the observation results were recorded, with the safety test results shown in table 3.

TABLE 2 skin response grading Standard for skin Enclosed Patch test

TABLE 3 safety test results

As can be seen from tables 2-3, the body lotion prepared by the technical scheme disclosed by the invention is safe and non-irritant to the body, and can be used with confidence.

2) Moisture retention test

Referring to 'evaluation guideline for efficacy of moisturizing cosmetic'), examples 1 to 5 and comparative examples 1 to 5 were subjected to a moisturizing test, 60 volunteers between 18 and 30 years old were selected as test subjects, the test subjects were divided into 10 groups, 6 subjects were included in each group, no product was used for the test sites 2 to 3 days before the test, no water was allowed to contact the test sites within 3 hours before the test, the inner sides of the forearms of both hands were uniformly cleaned with dry facial tissues, the area of the test site was 3cm × 3cm, and the test samples were measured at 2mg/cm²The dosage of the composition is coated with a latex finger cot for a single time, the composition is statically placed in a room for 30min before the test, the composition is tested by a Corneometer CM825, the composition is tested once before the use of the sample and once 15min, 2h and 4h after the use of the sample respectively, the average value is taken, and the test result is shown in Table 4.

Table 4 skin moisture content test results (%)

As can be seen from Table 4, the skin moisture content test results after the body lotion of examples 1-5 is used are significantly higher than those of comparative examples 1-5, which shows that the combination of the eriodictyon root extract, the kiwi fruit extract, the bistort rhizome extract, the ophiopogon root tuber extract and the maca root extract has the efficacy of synergistically improving the moisture retention of the product.

3) Whitening efficacy test

Whitening efficacy tests were performed on examples 1 to 5 and comparative examples 1 to 5, and the whitening efficacy was characterized by the tyrosinase activity inhibition. Preparing 1.5g/L levodopa by 0.01mol/L phosphate buffer solution with pH of 6.8, adding 40 μ L levodopa into a 96-well plate, adding 80 μ L phosphate buffer solution and 40mg test object body milk, adding 40 μ L100U/mL tyrosinase, mixing, reacting in 30 deg.C water bath for 30min, measuring absorbance at 490nm, using 40 μ L phosphate buffer solution as blank control, and calculating tyrosinase activity inhibition rate according to the following formula.

Inhibition rate ═ 1- (T)₁-T₂)/(C₁-C₂)]×100％

In the formula C₁Absorbance when no enzyme was added to the sample, C₂Absorbance without enzyme and without sample, T₁Is the absorbance, T, at the time of addition of enzyme to the sample₂Absorbance without enzyme plus sample. The test results are shown in table 5.

TABLE 5 tyrosinase activity inhibition ratio (%)

As can be seen from Table 5, the inhibition rate of the tyrosinase activity in the examples 1 to 5 is obviously higher than that in the comparative examples 1 to 5, which shows that the body lotion disclosed by the invention can reduce the generation of melanin and improve the whitening effect.

4) Stability test

The body milk of the embodiments 1 to 5 is divided into 4 parts, each 10mL of the body milk is placed in a sealed plastic container, the body milk is placed in a thermostat at normal temperature and 48 ℃ and in a thermostat at-15 ℃ for 48 hours under the sun exposure, and the body milk is taken out and recovered to the room temperature, observed and compared, and no layering or precipitation appears, which shows that the body milk has better stability.

Finally, it should be noted that the above embodiments are only used for illustrating the technical solutions of the present invention and not for limiting the protection scope of the present invention, and although the present invention has been described in detail with reference to the preferred embodiments, it should be understood by those skilled in the art that modifications or equivalent substitutions can be made on the technical solutions of the present invention without departing from the spirit and scope of the technical solutions of the present invention.

Claims

1. A botanical composition comprising eriodictyon root extract, kiwi fruit extract, bistort rhizome extract, ophiopogon root tuber extract, and maca root extract.

2. The plant composition of claim 1, wherein the plant composition comprises the following ingredients in parts by weight: 10-20 parts of eriodictyon rhodiola root extract, 5-15 parts of kiwi fruit extract, 12-20 parts of bistort rhizome extract, 20-35 parts of radix ophiopogonis tuber extract and 20-35 parts of maca root extract.

3. The plant composition of claim 2, wherein the plant composition comprises the following ingredients in parts by weight: 17 parts of radix eriodictyon extract, 10 parts of kiwi fruit extract, 18 parts of bistort rhizome extract, 25 parts of radix ophiopogonis root tuber extract and 30 parts of maca root extract.

4. Use of a plant composition according to any one of claims 1 to 3 for the preparation of a body lotion.

5. A body lotion comprising the plant composition according to any one of claims 1 to 3, wherein the body lotion comprises an aqueous phase and an oil phase, the aqueous phase comprising the plant composition; the water phase also comprises one or more of an emulsifier, a thickening agent, a chelating agent, a preservative, an essence and a pH regulator; the oil phase comprises one or more of a humectant, an antioxidant and a film forming agent.

6. The body milk according to claim 5, characterized in that the emulsifier is glyceryl stearate/PEG-100 stearate; the thickening agent is acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer; the pH regulator is triethanolamine; the oil phase comprises at least one of isopropyl myristate, squalane, shea butter, glycerol, tocopherol, and coconut oil.

7. The body lotion according to claim 6, characterized in that it comprises the following components in mass fraction: 0.5-2% of glyceryl stearate/PEG-100 stearate, 0.1-0.5% of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, 0.1-0.5% of triethanolamine, 0.05-0.2% of chelating agent, 0.1-1% of preservative, 0.5-1% of essence, 1-5% of plant composition, 1-10% of isopropyl myristate, 1-15% of squalane, 1-15% of shea butter, 1-5% of glycerol, 0.5-1.5% of tocopherol and 1-5% of coconut oil.

8. A method for preparing the plant composition according to any one of claims 1 to 3, wherein the plant composition is prepared by: screening, washing, drying and grinding plant raw materials to obtain powder, then carrying out reflux extraction for 4-6 times by using alcohol with the volume fraction of 50% of ethanol, wherein each time is 30-90min to obtain an extract, and drying the extract after atmospheric concentration to obtain the plant composition.

9. A method for the preparation of a body lotion according to any of claims 6 to 7, comprising the steps of:

(1) adding the oil phase raw materials into an emulsifying pot, heating to dissolve the oil phase raw materials, and uniformly stirring to obtain a mixed solution A;

(2) adding glyceryl stearate/PEG-100 stearate, acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer and chelating agent into water, heating to dissolve, and stirring to obtain mixed solution B;

(3) adding the mixed solution A into the mixed solution B for emulsification, and emulsifying for 20-50min to obtain an emulsified liquid;

10. The method for preparing body milk according to claim 9, wherein in the step (3), the emulsification conditions are: emulsification was carried out at 60-75 ℃ and stirring was carried out at 1200-2500 rpm.