ZA200407156B - Macrocyclic compounds useful as pharmaceuticals - Google Patents

Macrocyclic compounds useful as pharmaceuticals Download PDF

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Publication number
ZA200407156B
ZA200407156B ZA200407156A ZA200407156A ZA200407156B ZA 200407156 B ZA200407156 B ZA 200407156B ZA 200407156 A ZA200407156 A ZA 200407156A ZA 200407156 A ZA200407156 A ZA 200407156A ZA 200407156 B ZA200407156 B ZA 200407156B
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ZA
South Africa
Prior art keywords
hydroxyl
compound
hydrogen
ester
halogen
Prior art date
Application number
ZA200407156A
Other languages
English (en)
Inventor
Boivin Roch
Du Hong
Goto Masaki
Jiang Yimin
Kawakami Yoshiyuki
Kuboi Yoshikazu
Matsushima Tomohiro
Shen Yong-Chun
Wang Yong-Chun
Wang John Yuan
Gusovsky Fabian
Chiba Kenichi
Eguchi Yoshihito
Harmange Jean-Christophe
Kawada Megumi
Kimura Akifumi
Lemelin Charles-Andru
Mizui Yoshiharu
Spyvee Mark
Yamamoto Satoshi
Muramoto Kenzo
Chow Jesse
Fujita Masanori
Inoue Atsushi
Kawai Takatoshi
Kotake Makoto
Li Xiang-Yi
Sakurai Hideki
Tanaka Isao
Yoneda Naoki
Shirota Hiroshi
Original Assignee
Eisai Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd
Publication of ZA200407156B publication Critical patent/ZA200407156B/en

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
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    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
    • A61K31/36—Compounds containing methylenedioxyphenyl groups, e.g. sesamin
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
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    • C—CHEMISTRY; METALLURGY
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    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
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    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
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    • C07D491/04—Ortho-condensed systems
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    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
ZA200407156A 2002-03-08 2004-09-07 Macrocyclic compounds useful as pharmaceuticals ZA200407156B (en)

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US36288302P 2002-03-08 2002-03-08
US38071102P 2002-05-14 2002-05-14

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ZA200407156B true ZA200407156B (en) 2006-12-27

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US (3) US7799827B2 (pl)
EP (2) EP2308861B1 (pl)
JP (3) JP4575667B2 (pl)
KR (1) KR101210018B1 (pl)
CN (2) CN1653059A (pl)
AU (2) AU2003224672B2 (pl)
BR (1) BRPI0308113B8 (pl)
CA (1) CA2478065C (pl)
ES (1) ES2555307T3 (pl)
IL (1) IL163711A0 (pl)
MX (1) MXPA04008722A (pl)
NO (1) NO332383B1 (pl)
NZ (1) NZ535101A (pl)
PL (1) PL221491B1 (pl)
RU (1) RU2334744C2 (pl)
TW (1) TWI343916B (pl)
WO (1) WO2003076424A1 (pl)
ZA (1) ZA200407156B (pl)

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US20060247448A1 (en) 2006-11-02
TWI343916B (en) 2011-06-21
NO20044256L (no) 2004-12-07
AU2003224672A1 (en) 2003-09-22
EP2308861B1 (en) 2017-03-01
NZ535101A (en) 2007-07-27
JP4575667B2 (ja) 2010-11-04
BRPI0308113B8 (pt) 2021-05-25
CN1653059A (zh) 2005-08-10
TW200407320A (en) 2004-05-16
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AU2003224672B2 (en) 2010-02-04
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