NO20092874L - Forhindring og behandling av amyloidogen sykdom - Google Patents
Forhindring og behandling av amyloidogen sykdomInfo
- Publication number
- NO20092874L NO20092874L NO20092874A NO20092874A NO20092874L NO 20092874 L NO20092874 L NO 20092874L NO 20092874 A NO20092874 A NO 20092874A NO 20092874 A NO20092874 A NO 20092874A NO 20092874 L NO20092874 L NO 20092874L
- Authority
- NO
- Norway
- Prior art keywords
- methods
- treatment
- prevention
- amyloidogenic disease
- disease
- Prior art date
Links
- 102000009091 Amyloidogenic Proteins Human genes 0.000 title abstract 2
- 108010048112 Amyloidogenic Proteins Proteins 0.000 title abstract 2
- 230000003942 amyloidogenic effect Effects 0.000 title abstract 2
- 201000010099 disease Diseases 0.000 title abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 2
- 230000002265 prevention Effects 0.000 title 1
- 208000024827 Alzheimer disease Diseases 0.000 abstract 1
- 230000003941 amyloidogenesis Effects 0.000 abstract 1
- 230000009286 beneficial effect Effects 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 230000000069 prophylactic effect Effects 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
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- A61K31/739—Lipopolysaccharides
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- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
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- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
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- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K2319/00—Fusion polypeptide
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
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- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
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- Veterinary Medicine (AREA)
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- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
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- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Toxicology (AREA)
- Virology (AREA)
- Marine Sciences & Fisheries (AREA)
- Mycology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Det er beskrevet sammensetninger og fremgangsmåter for behandling av amyloidogene sykdommer. Slike fremgangsmåter innbefatter administrering av et middel som induserer en fordelaktig immunrespons overfor en amyloid deponering i pasienten. Fremgangsmåtene er spesielt nyttige for profylaktisk og terapeutisk behandling av Alzheimers sykdom. I slike metoder utgjør et egnet middel A?-peptid eller et antistoff derav.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US6774097P | 1997-12-02 | 1997-12-02 | |
US8097098P | 1998-04-07 | 1998-04-07 | |
PCT/US1998/025386 WO1999027944A1 (en) | 1997-12-02 | 1998-11-30 | Prevention and treatment of amyloidogenic disease |
Publications (2)
Publication Number | Publication Date |
---|---|
NO20092874L true NO20092874L (no) | 2000-07-31 |
NO331425B1 NO331425B1 (no) | 2011-12-27 |
Family
ID=26748211
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20002784A NO328865B1 (no) | 1997-12-02 | 2000-05-31 | Farmasoytisk sammensetning og immunogent middel samt anvendelse derav |
NO20092874A NO331425B1 (no) | 1997-12-02 | 2009-08-21 | Konjugat omfattende et middel koblet til et baererprotein, anvendelse derav samt farmasoytisk sammensetning |
NO20100061A NO332813B1 (no) | 1997-12-02 | 2010-01-15 | Farmasoytisk sammensetning samt in vitro metoder |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20002784A NO328865B1 (no) | 1997-12-02 | 2000-05-31 | Farmasoytisk sammensetning og immunogent middel samt anvendelse derav |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20100061A NO332813B1 (no) | 1997-12-02 | 2010-01-15 | Farmasoytisk sammensetning samt in vitro metoder |
Country Status (38)
Country | Link |
---|---|
US (26) | US20040171815A1 (no) |
EP (5) | EP1033996B1 (no) |
JP (4) | JP4677094B2 (no) |
KR (3) | KR101248711B1 (no) |
CN (1) | CN100374151C (no) |
AR (1) | AR020050A1 (no) |
AT (4) | ATE493149T1 (no) |
AU (1) | AU1706199A (no) |
BG (1) | BG104562A (no) |
BR (1) | BR9815357A (no) |
CA (1) | CA2312920C (no) |
CO (1) | CO4980846A1 (no) |
CY (3) | CY1108331T1 (no) |
CZ (1) | CZ303137B6 (no) |
DE (7) | DE06075704T1 (no) |
DK (4) | DK1033996T3 (no) |
EA (3) | EA007218B1 (no) |
EE (1) | EE05377B1 (no) |
ES (4) | ES2428740T3 (no) |
GE (2) | GEP20053715B (no) |
HK (2) | HK1095265A1 (no) |
HR (2) | HRP20000443B1 (no) |
HU (2) | HU228061B1 (no) |
ID (1) | ID25504A (no) |
IL (5) | IL136252A0 (no) |
IS (1) | IS5500A (no) |
MY (1) | MY134906A (no) |
NO (3) | NO328865B1 (no) |
NZ (1) | NZ504569A (no) |
PE (1) | PE20001383A1 (no) |
PL (2) | PL202706B1 (no) |
PT (4) | PT2305282E (no) |
SA (1) | SA99191269B1 (no) |
SG (1) | SG111083A1 (no) |
SI (4) | SI1679080T1 (no) |
TR (1) | TR200001608T2 (no) |
TW (1) | TWI239847B (no) |
WO (1) | WO1999027944A1 (no) |
Families Citing this family (293)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1997021728A1 (en) | 1995-12-12 | 1997-06-19 | Karolinska Innovations Ab | PEPTIDE BINDING THE KLVFF-SEQUENCE OF AMYLOID $g(b) |
US8173127B2 (en) * | 1997-04-09 | 2012-05-08 | Intellect Neurosciences, Inc. | Specific antibodies to amyloid beta peptide, pharmaceutical compositions and methods of use thereof |
US6703015B1 (en) | 1999-09-03 | 2004-03-09 | Ramot At Tel-Aviv University Ltd. | Filamentous bacteriophage displaying an β-amyloid epitope |
US7790856B2 (en) | 1998-04-07 | 2010-09-07 | Janssen Alzheimer Immunotherapy | Humanized antibodies that recognize beta amyloid peptide |
US7179892B2 (en) * | 2000-12-06 | 2007-02-20 | Neuralab Limited | Humanized antibodies that recognize beta amyloid peptide |
US6761888B1 (en) * | 2000-05-26 | 2004-07-13 | Neuralab Limited | Passive immunization treatment of Alzheimer's disease |
US20080050367A1 (en) | 1998-04-07 | 2008-02-28 | Guriq Basi | Humanized antibodies that recognize beta amyloid peptide |
US7964192B1 (en) * | 1997-12-02 | 2011-06-21 | Janssen Alzheimer Immunotherapy | Prevention and treatment of amyloidgenic disease |
US7588766B1 (en) * | 2000-05-26 | 2009-09-15 | Elan Pharma International Limited | Treatment of amyloidogenic disease |
US6750324B1 (en) | 1997-12-02 | 2004-06-15 | Neuralab Limited | Humanized and chimeric N-terminal amyloid beta-antibodies |
US6787523B1 (en) | 1997-12-02 | 2004-09-07 | Neuralab Limited | Prevention and treatment of amyloidogenic disease |
TWI239847B (en) * | 1997-12-02 | 2005-09-21 | Elan Pharm Inc | N-terminal fragment of Abeta peptide and an adjuvant for preventing and treating amyloidogenic disease |
US6743427B1 (en) | 1997-12-02 | 2004-06-01 | Neuralab Limited | Prevention and treatment of amyloidogenic disease |
US20050059802A1 (en) * | 1998-04-07 | 2005-03-17 | Neuralab Ltd | Prevention and treatment of amyloidogenic disease |
CN1589903A (zh) * | 1998-05-21 | 2005-03-09 | 田纳西州立大学研究基金会 | 用淀粉样蛋白抗体除去淀粉样蛋白的方法 |
US20030147882A1 (en) | 1998-05-21 | 2003-08-07 | Alan Solomon | Methods for amyloid removal using anti-amyloid antibodies |
US7060670B1 (en) | 1999-05-05 | 2006-06-13 | Neurochem (International) Limited | Stereoselective antifibrillogenic peptides and peptidomimetics thereof |
EP1178825B1 (en) * | 1999-05-13 | 2011-07-13 | Wyeth Holdings Corporation | Adjuvant combination formulations |
AU2008203784B2 (en) * | 1999-05-28 | 2012-01-19 | Janssen Alzheimer Immunotherapy | Prevention and treatment of amyloidogenic disease |
US6787637B1 (en) | 1999-05-28 | 2004-09-07 | Neuralab Limited | N-Terminal amyloid-β antibodies |
UA81216C2 (en) | 1999-06-01 | 2007-12-25 | Prevention and treatment of amyloid disease | |
AR024558A1 (es) * | 1999-06-01 | 2002-10-16 | Neuralab Ltd | Composiciones del peptido a-beta y procesos para producir las mismas |
AU2005202644B2 (en) * | 1999-06-01 | 2009-03-05 | Janssen Alzheimer Immunotherapy | Prevention and treatment of amyloidogenic disease |
CA2376693C (en) | 1999-06-16 | 2013-09-10 | Boston Biomedical Research Institute | Immunological control of .beta.-amyloid levels in vivo |
JP2003509020A (ja) * | 1999-09-03 | 2003-03-11 | ラモット・ユニバーシティ・オーソリティ・フォー・アプライド・リサーチ・アンド・インダストリアル・ディベロップメント・リミテッド | プラーク形成疾患の診断、治療、予防に有用な薬剤、組成物、その使用法 |
US7384640B1 (en) | 1999-09-30 | 2008-06-10 | Wyeth Holdings Corporation | Mutant cholera holotoxin as an adjuvant |
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