ATE197670T1 - Parenterales busulfan zur behandlung von malignen krankheiten - Google Patents
Parenterales busulfan zur behandlung von malignen krankheitenInfo
- Publication number
- ATE197670T1 ATE197670T1 AT94929116T AT94929116T ATE197670T1 AT E197670 T1 ATE197670 T1 AT E197670T1 AT 94929116 T AT94929116 T AT 94929116T AT 94929116 T AT94929116 T AT 94929116T AT E197670 T1 ATE197670 T1 AT E197670T1
- Authority
- AT
- Austria
- Prior art keywords
- treatment
- busulfan
- malignant diseases
- parenteral
- parenteral busulfan
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/255—Esters, e.g. nitroglycerine, selenocyanates of sulfoxy acids or sulfur analogues thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/40—Cyclodextrins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Emergency Medicine (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Inorganic Chemistry (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Transplantation (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/129,995 US5430057A (en) | 1993-09-30 | 1993-09-30 | Parenteral busulfan for treatment of malignant disease |
PCT/US1994/009748 WO1995008991A1 (en) | 1993-09-30 | 1994-08-30 | Parenteral busulfan for treatment of malignant disease |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE197670T1 true ATE197670T1 (de) | 2000-12-15 |
Family
ID=22442547
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT94929116T ATE197670T1 (de) | 1993-09-30 | 1994-08-30 | Parenterales busulfan zur behandlung von malignen krankheiten |
Country Status (13)
Country | Link |
---|---|
US (2) | US5430057A (de) |
EP (1) | EP0725637B1 (de) |
JP (1) | JP3599285B2 (de) |
KR (1) | KR100371826B1 (de) |
AT (1) | ATE197670T1 (de) |
AU (1) | AU694141B2 (de) |
CA (1) | CA2171738C (de) |
DE (1) | DE69426334T2 (de) |
DK (1) | DK0725637T3 (de) |
ES (1) | ES2153862T3 (de) |
GR (1) | GR3035447T3 (de) |
PT (1) | PT725637E (de) |
WO (1) | WO1995008991A1 (de) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5877205A (en) * | 1996-06-28 | 1999-03-02 | Board Of Regents, The University Of Texas System | Parenteral paclitaxel in a stable non-toxic formulation |
US6045815A (en) * | 1997-08-15 | 2000-04-04 | Board Of Regents, The University Of Texas System | Parenteral pimaricin as treatment of systemic infections |
US6844004B2 (en) | 1997-08-15 | 2005-01-18 | Board Of Regents, The University Of Texas System | Topical formulations of natamycin/pimaricin |
US6734338B1 (en) | 1997-11-14 | 2004-05-11 | Cedars-Sinai Medical Center | Transfection, storage and transfer of male germ cells for generation of transgenic species and genetic therapies |
DE69840671D1 (de) * | 1997-11-14 | 2009-04-30 | Cedars Sinai Medical Center | Transfektion und transfer nicht humaner männlicher keimzellen zur generierung transgener nicht humaner säugetiere |
US7294755B1 (en) | 1997-11-14 | 2007-11-13 | Cedars-Sinai Medical Center | Genetic modification of male germ cells for generation of transgenic species and genetic therapies |
US7351427B2 (en) * | 1998-06-18 | 2008-04-01 | Busulipo Ab | Pharmaceutical composition, a method of preparing it and a method of treatment by use thereof |
US20080131498A1 (en) * | 1998-06-18 | 2008-06-05 | Busulipo Ab | Pharmaceutical composition, a method of preparing it and a method of treatment by use thereof |
WO1999065481A1 (en) * | 1998-06-18 | 1999-12-23 | Karolinska Innovations Ab | Liposomal formulations of busulphan |
HUP0303930A3 (en) * | 2001-01-26 | 2012-09-28 | Univ Emory | Methods of inducing organ transplant tolerance and correcting hemoglobinopathies |
US7122640B2 (en) * | 2002-06-10 | 2006-10-17 | Phynexus, Inc. | Open channel solid phase extraction systems and methods |
JP2005535644A (ja) * | 2002-06-26 | 2005-11-24 | ファルマシア コーポレイション | 安定な非経口パレコキシブ液体製剤 |
US8034831B2 (en) | 2002-11-06 | 2011-10-11 | Celgene Corporation | Methods for the treatment and management of myeloproliferative diseases using 4-(amino)-2-(2,6-Dioxo(3-piperidyl)-isoindoline-1,3-dione in combination with other therapies |
US7563810B2 (en) | 2002-11-06 | 2009-07-21 | Celgene Corporation | Methods of using 3-(4-amino-1-oxo-1,3-dihydroisoindol-2-yl)-piperidine-2,6-dione for the treatment and management of myeloproliferative diseases |
CA2565447A1 (en) * | 2004-05-05 | 2005-12-01 | Celgene Corporation | Method of using and compositions comprising immunomodulatory compounds for the treatment and management of myeloproliferative diseases |
JP4486994B2 (ja) * | 2004-09-15 | 2010-06-23 | サラダックス バイオメディカル インコーポレイテッド | ブスルファンイムノアッセイ |
WO2008157785A1 (en) * | 2007-06-20 | 2008-12-24 | University Of Louisville Research Foundation, Inc. | T cell depleting compositions useful for treating cancer |
CN102151257B (zh) * | 2011-02-17 | 2015-03-04 | 四川科瑞德凯华制药有限公司 | 一种白消安注射剂及其制备方法 |
PL2701684T3 (pl) | 2011-04-28 | 2018-09-28 | Platform Brightworks Two, Ltd. | Ulepszone preparaty pozajelitowe lipofilowych środków farmaceutycznych oraz sposoby ich wytwarzania i stosowania |
CN103446045B (zh) * | 2012-06-01 | 2015-08-12 | 四川科瑞德凯华制药有限公司 | 一种稳定的白消安注射剂 |
WO2014089957A1 (zh) * | 2012-12-11 | 2014-06-19 | 四川科瑞德凯华制药有限公司 | 一种稳定的白消安注射剂 |
CN105726467A (zh) * | 2014-12-09 | 2016-07-06 | 四川科瑞德制药有限公司 | 一种白消安注射液及其制备方法 |
AU2018263924B2 (en) * | 2017-05-03 | 2024-07-04 | Cydex Pharmaceuticals, Inc. | Composition containing cyclodextrin and busulfan |
CN109078005B (zh) * | 2018-08-07 | 2021-11-26 | 江苏领航生物科技有限公司 | 一种白消安组合物及其制备方法和应用 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3109783A1 (de) * | 1981-03-13 | 1982-10-07 | Sanol Schwarz-Monheim Gmbh, 4019 Monheim | Mit wasser zu einer etwa isotonischen nitroglycerinloesung aufloesbare zubereitung und derartige nitroglycerinloesung |
JPS6461429A (en) * | 1987-08-29 | 1989-03-08 | Akio Hagiwara | Remedy for cancer |
US5180716A (en) * | 1990-08-01 | 1993-01-19 | The Regents Of The University Of California | Cyclodextrin complexes for neuraxial administration of drugs |
-
1993
- 1993-09-30 US US08/129,995 patent/US5430057A/en not_active Expired - Lifetime
-
1994
- 1994-08-30 CA CA002171738A patent/CA2171738C/en not_active Expired - Lifetime
- 1994-08-30 EP EP94929116A patent/EP0725637B1/de not_active Expired - Lifetime
- 1994-08-30 AU AU78290/94A patent/AU694141B2/en not_active Expired
- 1994-08-30 PT PT94929116T patent/PT725637E/pt unknown
- 1994-08-30 DE DE69426334T patent/DE69426334T2/de not_active Expired - Lifetime
- 1994-08-30 KR KR1019960701624A patent/KR100371826B1/ko not_active IP Right Cessation
- 1994-08-30 AT AT94929116T patent/ATE197670T1/de active
- 1994-08-30 ES ES94929116T patent/ES2153862T3/es not_active Expired - Lifetime
- 1994-08-30 JP JP51031195A patent/JP3599285B2/ja not_active Expired - Lifetime
- 1994-08-30 WO PCT/US1994/009748 patent/WO1995008991A1/en active IP Right Grant
- 1994-08-30 DK DK94929116T patent/DK0725637T3/da active
-
1995
- 1995-05-24 US US08/449,685 patent/US5559148A/en not_active Expired - Lifetime
-
2001
- 2001-02-21 GR GR20010400278T patent/GR3035447T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
EP0725637B1 (de) | 2000-11-22 |
JP3599285B2 (ja) | 2004-12-08 |
US5430057A (en) | 1995-07-04 |
DE69426334T2 (de) | 2001-03-29 |
DK0725637T3 (da) | 2001-03-26 |
US5559148A (en) | 1996-09-24 |
CA2171738A1 (en) | 1995-04-06 |
DE69426334D1 (de) | 2000-12-28 |
KR100371826B1 (ko) | 2003-05-09 |
JPH09502996A (ja) | 1997-03-25 |
KR960704543A (ko) | 1996-10-09 |
GR3035447T3 (en) | 2001-05-31 |
AU694141B2 (en) | 1998-07-16 |
WO1995008991A1 (en) | 1995-04-06 |
CA2171738C (en) | 2002-07-16 |
ES2153862T3 (es) | 2001-03-16 |
PT725637E (pt) | 2001-06-29 |
EP0725637A1 (de) | 1996-08-14 |
AU7829094A (en) | 1995-04-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification |