|
US6096318A
(en)
|
1973-05-07 |
2000-08-01 |
The Ohio State University |
Antigenically modified HCG polypeptides
|
|
US4902506A
(en)
|
1983-07-05 |
1990-02-20 |
The University Of Rochester |
Immunogenic conjugates
|
|
GB8308235D0
(en)
|
1983-03-25 |
1983-05-05 |
Celltech Ltd |
Polypeptides
|
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
|
US5158769A
(en)
|
1984-03-07 |
1992-10-27 |
New York Blood Center, Inc. |
Pre-S gene coded peptide hepatitis B immunogens, vaccines, diagnostics, and synthetic lipid vesicle carriers
|
|
US5417986A
(en)
|
1984-03-16 |
1995-05-23 |
The United States Of America As Represented By The Secretary Of The Army |
Vaccines against diseases caused by enteropathogenic organisms using antigens encapsulated within biodegradable-biocompatible microspheres
|
|
US5208036A
(en)
|
1985-01-07 |
1993-05-04 |
Syntex (U.S.A.) Inc. |
N-(ω, (ω-1)-dialkyloxy)- and N-(ω, (ω-1)-dialkenyloxy)-alk-1-yl-N,N,N-tetrasubstituted ammonium lipids and uses therefor
|
|
US4666829A
(en)
|
1985-05-15 |
1987-05-19 |
University Of California |
Polypeptide marker for Alzheimer's disease and its use for diagnosis
|
|
DE3521994A1
(de)
|
1985-06-20 |
1987-01-02 |
Bayer Ag |
N-(2-aminoacylamido-2-desoxy-hexosyl)-amide-, -carbamate und -harnstoffe, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln
|
|
US5618920A
(en)
|
1985-11-01 |
1997-04-08 |
Xoma Corporation |
Modular assembly of antibody genes, antibodies prepared thereby and use
|
|
WO1987002671A1
(en)
|
1985-11-01 |
1987-05-07 |
International Genetic Engineering, Inc. |
Modular assembly of antibody genes, antibodies prepared thereby and use
|
|
US4713366A
(en)
|
1985-12-04 |
1987-12-15 |
The Ohio State University Research Foundation |
Antigenic modification of polypeptides
|
|
US5096706A
(en)
|
1986-03-25 |
1992-03-17 |
National Research Development Corporation |
Antigen-based treatment for adiposity
|
|
US6548640B1
(en)
|
1986-03-27 |
2003-04-15 |
Btg International Limited |
Altered antibodies
|
|
US5225539A
(en)
|
1986-03-27 |
1993-07-06 |
Medical Research Council |
Recombinant altered antibodies and methods of making altered antibodies
|
|
JPS62267297A
(ja)
|
1986-05-15 |
1987-11-19 |
Tokyo Met Gov Seishin Igaku Sogo Kenkyusho |
老人斑反応性モノクロ−ナル抗体、それを産生する細胞株及び該モノクロ−ナル抗体の製造方法
|
|
US5278049A
(en)
|
1986-06-03 |
1994-01-11 |
Incyte Pharmaceuticals, Inc. |
Recombinant molecule encoding human protease nexin
|
|
US5231170A
(en)
|
1986-08-27 |
1993-07-27 |
Paul Averback |
Antibodies to dense microspheres
|
|
US5187153A
(en)
|
1986-11-17 |
1993-02-16 |
Scios Nova Inc. |
Methods of treatment using Alzheimer's amyloid polypeptide derivatives
|
|
US5223482A
(en)
|
1986-11-17 |
1993-06-29 |
Scios Nova Inc. |
Recombinant Alzheimer's protease inhibitory amyloid protein and method of use
|
|
US5220013A
(en)
|
1986-11-17 |
1993-06-15 |
Scios Nova Inc. |
DNA sequence useful for the detection of Alzheimer's disease
|
|
US4879213A
(en)
|
1986-12-05 |
1989-11-07 |
Scripps Clinic And Research Foundation |
Synthetic polypeptides and antibodies related to Epstein-Barr virus early antigen-diffuse
|
|
DE3702789A1
(de)
|
1987-01-30 |
1988-08-18 |
Bayer Ag |
Vorlaeuferprotein des apc-polypeptids, dafuer codierende dna und diagnostische verwendung der dna und des proteins
|
|
US4912206A
(en)
|
1987-02-26 |
1990-03-27 |
The United States Of America As Represented By The Department Of Health And Human Services |
CDNA clone encoding brain amyloid of alzheimer's disease
|
|
WO1988007089A1
(en)
|
1987-03-18 |
1988-09-22 |
Medical Research Council |
Altered antibodies
|
|
JPS63245689A
(ja)
|
1987-03-31 |
1988-10-12 |
Suntory Ltd |
ヒトアミロイド関連蛋白モノクロ−ナル抗体
|
|
US4883666A
(en)
|
1987-04-29 |
1989-11-28 |
Massachusetts Institute Of Technology |
Controlled drug delivery system for treatment of neural disorders
|
|
US5258498A
(en)
|
1987-05-21 |
1993-11-02 |
Creative Biomolecules, Inc. |
Polypeptide linkers for production of biosynthetic proteins
|
|
US5057540A
(en)
|
1987-05-29 |
1991-10-15 |
Cambridge Biotech Corporation |
Saponin adjuvant
|
|
US5583112A
(en)
|
1987-05-29 |
1996-12-10 |
Cambridge Biotech Corporation |
Saponin-antigen conjugates and the use thereof
|
|
US5245015A
(en)
|
1991-04-26 |
1993-09-14 |
Tanox Biosystems, Inc. |
Monoclonal antibodies which neutralize HIV-1 through reaction with a conformational epitope in vitro
|
|
US5571500A
(en)
|
1987-06-24 |
1996-11-05 |
Autoimmune, Inc. |
Treatment of autoimmune diseases through administration by inhalation of autoantigens
|
|
US5641474A
(en)
|
1987-06-24 |
1997-06-24 |
Autoimmune, Inc. |
Prevention of autoimmune diseases by aerosol administration of autoantigens
|
|
US5645820A
(en)
|
1987-06-24 |
1997-07-08 |
Autoimmune, Inc. |
Treatment of autoimmune diseases by aerosol administration of autoantigens
|
|
AU632991B2
(en)
|
1987-06-24 |
1993-01-21 |
Autoimmune, Inc. |
Treatment of autoimmune diseases by oral administration of autoantigens
|
|
US5571499A
(en)
|
1987-06-24 |
1996-11-05 |
Autoimmune, Inc. |
Treatment of autoimmune diseases by aerosol administration of autoantigens
|
|
US5869054A
(en)
|
1987-06-24 |
1999-02-09 |
Autoimmune Inc. |
Treatment of multiple sclerosis by oral administration of autoantigens
|
|
US5849298A
(en)
|
1987-06-24 |
1998-12-15 |
Autoimmune Inc. |
Treatment of multiple sclerosis by oral administration of bovine myelin
|
|
US5004697A
(en)
|
1987-08-17 |
1991-04-02 |
Univ. Of Ca |
Cationized antibodies for delivery through the blood-brain barrier
|
|
US4966753A
(en)
|
1987-08-18 |
1990-10-30 |
Molecular Rx, Inc. |
Immunotherapeutic methods and compositions employing antigens characteristic of malignant neoplasms
|
|
US5677425A
(en)
|
1987-09-04 |
1997-10-14 |
Celltech Therapeutics Limited |
Recombinant antibody
|
|
US5336603A
(en)
|
1987-10-02 |
1994-08-09 |
Genentech, Inc. |
CD4 adheson variants
|
|
CA1339014C
(en)
|
1987-10-08 |
1997-03-25 |
Ronald E. Majocha |
Antibodies to a4 amyloid peptide
|
|
US5231000A
(en)
|
1987-10-08 |
1993-07-27 |
The Mclean Hospital |
Antibodies to A4 amyloid peptide
|
|
EP0382781B1
(en)
|
1987-10-23 |
1993-09-29 |
Genetics Institute, Inc. |
Composition for treating cancers characterized by over-expression of the c-fms proto-oncogene
|
|
US5089603A
(en)
|
1989-06-21 |
1992-02-18 |
Tanox Biosystems, Inc. |
Antigenic epitopes present on membrane-bound but not secreted iga
|
|
AU3056289A
(en)
|
1988-01-13 |
1989-08-11 |
Mclean Hospital Corporation, The |
Genetic constructs containing the alzheimer brain amyloid gene
|
|
US4912094B1
(en)
|
1988-06-29 |
1994-02-15 |
Ribi Immunochem Research Inc. |
Modified lipopolysaccharides and process of preparation
|
|
US5576184A
(en)
|
1988-09-06 |
1996-11-19 |
Xoma Corporation |
Production of chimeric mouse-human antibodies with specificity to human tumor antigens
|
|
KR900005995A
(ko)
|
1988-10-31 |
1990-05-07 |
우메모또 요시마사 |
변형 인터류킨-2 및 그의 제조방법
|
|
EP0442926A1
(en)
|
1988-11-10 |
1991-08-28 |
Imperial Cancer Research Technology Limited |
Polypeptides
|
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
|
IL162181A
(en)
|
1988-12-28 |
2006-04-10 |
Pdl Biopharma Inc |
A method of producing humanized immunoglubulin, and polynucleotides encoding the same
|
|
US5227159A
(en)
|
1989-01-31 |
1993-07-13 |
Miller Richard A |
Anti-idiotype antibodies reactive with shared idiotopes expressed by B cell lymphomas and autoantibodies
|
|
US5262332A
(en)
|
1989-04-05 |
1993-11-16 |
Brigham And Women's Hospital |
Diagnostic method for Alzheimer's disease: examination of non-neural tissue
|
|
AU5525090A
(en)
|
1989-04-14 |
1990-11-16 |
Research Foundation For Mental Hygiene, Inc. |
Monoclonal antibody to amyloid peptide
|
|
AU5439790A
(en)
|
1989-04-14 |
1990-11-16 |
Research Foundation For Mental Hygiene, Inc. |
Cerebrovascular amyloid protein-specific monoclonal antibody sv17-6e10
|
|
EP0394827A1
(en)
|
1989-04-26 |
1990-10-31 |
F. Hoffmann-La Roche Ag |
Chimaeric CD4-immunoglobulin polypeptides
|
|
CA2017507C
(en)
|
1989-05-25 |
1996-11-12 |
Gary Van Nest |
Adjuvant formulation comprising a submicron oil droplet emulsion
|
|
JPH0319929A
(ja)
|
1989-06-14 |
1991-01-29 |
Asahi Chem Ind Co Ltd |
オープンエンド紡績の糸
|
|
US5112946A
(en)
|
1989-07-06 |
1992-05-12 |
Repligen Corporation |
Modified pf4 compositions and methods of use
|
|
ATE190496T1
(de)
|
1989-12-20 |
2000-04-15 |
Autoimmune Inc |
Behandlung von autoimmunkrankheiten durch verabreichung von autoantigenen in form von aerosol
|
|
GB8928874D0
(en)
|
1989-12-21 |
1990-02-28 |
Celltech Ltd |
Humanised antibodies
|
|
US5859205A
(en)
|
1989-12-21 |
1999-01-12 |
Celltech Limited |
Humanised antibodies
|
|
EP1690935A3
(en)
|
1990-01-12 |
2008-07-30 |
Abgenix, Inc. |
Generation of xenogeneic antibodies
|
|
EP0782859A1
(en)
|
1990-03-02 |
1997-07-09 |
Autoimmune, Inc. |
Enhancement of the down-regulation of autoimmune diseases by oral administration of autoantigens
|
|
EP0451700A1
(en)
|
1990-04-10 |
1991-10-16 |
Miles Inc. |
Recombinant APP minigenes for expression in transgenic mice as models for Alzheimers's disease
|
|
EP0527823A1
(en)
|
1990-04-24 |
1993-02-24 |
The Regents Of The University Of California |
Purification, detection and methods of use of protease nexin-2
|
|
JP2703096B2
(ja)
|
1990-04-26 |
1998-01-26 |
三菱重工業株式会社 |
コンベア付きロボットシステムの教示方法
|
|
US5753624A
(en)
|
1990-04-27 |
1998-05-19 |
Milkhaus Laboratory, Inc. |
Materials and methods for treatment of plaquing disease
|
|
GB9009548D0
(en)
|
1990-04-27 |
1990-06-20 |
Celltech Ltd |
Chimeric antibody and method
|
|
EP0526511B1
(en)
|
1990-04-27 |
1997-05-28 |
MCMICHAEL, John |
Method and composition for treatment of central nervous systems disease states associated with abnormal amyloid beta protein
|
|
US5427908A
(en)
|
1990-05-01 |
1995-06-27 |
Affymax Technologies N.V. |
Recombinant library screening methods
|
|
JPH0415492A
(ja)
|
1990-05-10 |
1992-01-20 |
Mitsubishi Electric Corp |
磁石発電機の冷却ファンおよびその製造方法
|
|
US5349053A
(en)
|
1990-06-01 |
1994-09-20 |
Protein Design Labs, Inc. |
Chimeric ligand/immunoglobulin molecules and their uses
|
|
ATE260974T1
(de)
|
1990-06-15 |
2004-03-15 |
Scios Inc |
Transgenes, nicht-menschliches säugetier das die amyloidbildende pathologie der alzheimerschen krankheit zeigt
|
|
WO1991019795A1
(en)
|
1990-06-19 |
1991-12-26 |
Immuvax |
Nonpathogenic variant virus
|
|
GB9014932D0
(en)
|
1990-07-05 |
1990-08-22 |
Celltech Ltd |
Recombinant dna product and method
|
|
GB9015198D0
(en)
|
1990-07-10 |
1990-08-29 |
Brien Caroline J O |
Binding substance
|
|
US5780587A
(en)
|
1990-08-24 |
1998-07-14 |
President And Fellows Of Harvard College |
Compounds and methods for inhibiting β-protein filament formation and neurotoxicity
|
|
US5814318A
(en)
|
1990-08-29 |
1998-09-29 |
Genpharm International Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
|
US5633425A
(en)
|
1990-08-29 |
1997-05-27 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US5877397A
(en)
|
1990-08-29 |
1999-03-02 |
Genpharm International Inc. |
Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
|
|
US5545806A
(en)
|
1990-08-29 |
1996-08-13 |
Genpharm International, Inc. |
Ransgenic non-human animals for producing heterologous antibodies
|
|
US5789650A
(en)
|
1990-08-29 |
1998-08-04 |
Genpharm International, Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
|
KR100272077B1
(ko)
|
1990-08-29 |
2000-11-15 |
젠팜인터내셔날,인코포레이티드 |
이종 항체를 생산할 수 있는 전이유전자를 가진 인간이외의 동물
|
|
WO1993012227A1
(en)
|
1991-12-17 |
1993-06-24 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US5770429A
(en)
|
1990-08-29 |
1998-06-23 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US5625126A
(en)
|
1990-08-29 |
1997-04-29 |
Genpharm International, Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
|
US5874299A
(en)
|
1990-08-29 |
1999-02-23 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US5661016A
(en)
|
1990-08-29 |
1997-08-26 |
Genpharm International Inc. |
Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
|
|
NZ239643A
(en)
|
1990-09-17 |
1996-05-28 |
North American Vaccine Inc |
Vaccine containing bacterial polysaccharide protein conjugate and adjuvant (c-nd-che-a-co-b-r) with a long chain alkyl group.
|
|
US5702906A
(en)
|
1990-09-25 |
1997-12-30 |
Genentech, Inc. |
Antibodies to neurotrophic factor-4 (NT-4)
|
|
WO1992006187A1
(en)
|
1990-09-28 |
1992-04-16 |
The Upjohn Company |
Transgenic animals with alzheimer's amyloid precursor gene
|
|
DK0553244T4
(da)
|
1990-10-05 |
2005-08-01 |
Celldex Therapeutics Inc |
Målrettet immunostimulering med bispecifikke reagenser
|
|
KR0140841B1
(ko)
|
1990-10-15 |
1998-06-01 |
조앤 월리스 |
자기항원의 경구 투여에 의한 자기면역 질병의 치료
|
|
GB9023352D0
(en)
|
1990-10-26 |
1990-12-05 |
Lynxvale Ltd |
Vaccinia vectors,vaccinia genes and expression products thereof
|
|
WO1992010591A1
(en)
|
1990-12-14 |
1992-06-25 |
Cell Genesys, Inc. |
Chimeric chains for receptor-associated signal transduction pathways
|
|
EP0971033B1
(en)
|
1991-01-21 |
2009-10-28 |
Elan Pharmaceuticals, Inc. |
Test and model for Alzheimer's disease
|
|
ATE194625T1
(de)
|
1991-03-01 |
2000-07-15 |
Merial Sas |
Verfahren zur immunoneutralisierung von nichtkastrierten männlichen haustieren gegen lmrh und peptide dafür
|
|
US5192753A
(en)
|
1991-04-23 |
1993-03-09 |
Mcgeer Patrick L |
Anti-rheumatoid arthritic drugs in the treatment of dementia
|
|
ATE182791T1
(de)
|
1991-05-08 |
1999-08-15 |
Schweiz Serum & Impfinst |
Wiederhergestellte influenza-virosomen mit immunostimulierenden und immunoverstärkenden eigenschaften und diese enthaltende impfstoffe
|
|
WO1994004679A1
(en)
|
1991-06-14 |
1994-03-03 |
Genentech, Inc. |
Method for making humanized antibodies
|
|
ATE255131T1
(de)
|
1991-06-14 |
2003-12-15 |
Genentech Inc |
Humanisierter heregulin antikörper
|
|
US5844095A
(en)
|
1991-06-27 |
1998-12-01 |
Bristol-Myers Squibb Company |
CTLA4 Ig fusion proteins
|
|
US5672805A
(en)
|
1991-07-18 |
1997-09-30 |
The Regents Of The University Of California |
Transgenic mice expressing the neurotoxic C-terminus of β-amyloid precursor protein
|
|
JP2966592B2
(ja)
|
1991-07-20 |
1999-10-25 |
萩原 義秀 |
安定化されたヒトモノクローナル抗体製剤
|
|
US5434050A
(en)
|
1991-08-13 |
1995-07-18 |
Regents Of The University Of Minnesota |
Labelled β-amyloid peptide and methods of screening for Alzheimer's disease
|
|
US5837268A
(en)
|
1991-10-16 |
1998-11-17 |
University Of Saskatchewan |
GnRH-leukotoxin chimeras
|
|
EP0620849B1
(en)
|
1992-01-07 |
2003-06-25 |
Elan Pharmaceuticals, Inc. |
Transgenic animal models for alzheimer's disease
|
|
US5622929A
(en)
|
1992-01-23 |
1997-04-22 |
Bristol-Myers Squibb Company |
Thioether conjugates
|
|
US5679348A
(en)
|
1992-02-03 |
1997-10-21 |
Cedars-Sinai Medical Center |
Immunotherapy for recurrent HSV infections
|
|
EP0911036A3
(en)
|
1992-02-11 |
2001-05-09 |
Henry M. Jackson Foundation For The Advancement Of Military Medicine |
Dual carrier immunogenic construct
|
|
ATE228373T1
(de)
|
1992-02-28 |
2002-12-15 |
Autoimmune Inc |
Unterdrückung von autoimmunkrankheiten durch antigene in wartestellung
|
|
US5714350A
(en)
|
1992-03-09 |
1998-02-03 |
Protein Design Labs, Inc. |
Increasing antibody affinity by altering glycosylation in the immunoglobulin variable region
|
|
EP0561087B1
(en)
|
1992-03-20 |
1999-08-04 |
N.V. Innogenetics S.A. |
Mutated form of the beta-amyloid precursor protein gene
|
|
US5447851B1
(en)
|
1992-04-02 |
1999-07-06 |
Univ Texas System Board Of |
Dna encoding a chimeric polypeptide comprising the extracellular domain of tnf receptor fused to igg vectors and host cells
|
|
US5441870A
(en)
|
1992-04-15 |
1995-08-15 |
Athena Neurosciences, Inc. |
Methods for monitoring cellular processing of β-amyloid precursor protein
|
|
US5604102A
(en)
|
1992-04-15 |
1997-02-18 |
Athena Neurosciences, Inc. |
Methods of screening for β-amyloid peptide production inhibitors
|
|
US5851787A
(en)
|
1992-04-20 |
1998-12-22 |
The General Hospital Corporation |
Nucleic acid encoding amyloid precursor-like protein and uses thereof
|
|
WO1993022332A2
(en)
|
1992-04-24 |
1993-11-11 |
Board Of Regents, The University Of Texas System |
Recombinant production of immunoglobulin-like domains in prokaryotic cells
|
|
GB9209118D0
(en)
|
1992-04-28 |
1992-06-10 |
Sb 120 Amsterdam Bv |
Vaccine compositions
|
|
PT652758E
(pt)
|
1992-06-18 |
2000-04-28 |
Harvard College |
Vacinas de toxina da difteria
|
|
SG90042A1
(en)
|
1992-06-25 |
2002-07-23 |
Smithkline Beecham Biolog |
Vaccine composition containing adjuvants
|
|
US6610493B1
(en)
|
1993-06-17 |
2003-08-26 |
Brigham And Women's Hospital |
Screening compounds for the ability to alter the production of amyloid-β peptide
|
|
US5766846A
(en)
|
1992-07-10 |
1998-06-16 |
Athena Neurosciences |
Methods of screening for compounds which inhibit soluble β-amyloid peptide production
|
|
US5837672A
(en)
|
1992-07-10 |
1998-11-17 |
Athena Neurosciences, Inc. |
Methods and compositions for the detection of soluble β-amyloid peptide
|
|
WO1994001772A1
(en)
|
1992-07-13 |
1994-01-20 |
The Children's Medical Center Corporation |
SCREEN FOR ALZHEIMER'S DISEASE THERAPEUTICS BASED ON β-AMYLOID PRODUCTION
|
|
IL102687A
(en)
|
1992-07-30 |
1997-06-10 |
Yeda Res & Dev |
Conjugates of poorly immunogenic antigens and synthetic pepide carriers and vaccines comprising them
|
|
WO1994003615A1
(en)
|
1992-07-31 |
1994-02-17 |
Medeva Holdings B.V. |
Expression of recombinant fusion proteins in attenuated bacteria
|
|
EP0667786B1
(en)
|
1992-08-27 |
2004-01-21 |
Deakin Research Limited |
Retro-, inverso-, and retro-inverso synthetic peptide analogues
|
|
US5958883A
(en)
|
1992-09-23 |
1999-09-28 |
Board Of Regents Of The University Of Washington Office Of Technology |
Animal models of human amyloidoses
|
|
WO1994009364A1
(en)
|
1992-10-13 |
1994-04-28 |
Duke University |
Method of inhibiting binding of amyloid precursor protein to beta-amyloid protein
|
|
JP3553592B2
(ja)
|
1992-10-26 |
2004-08-11 |
ビー． シェンク，デイル |
可溶性β−アミロイド・ペプチドの検出のための方法及び組成物
|
|
US5605811A
(en)
|
1992-10-26 |
1997-02-25 |
Athena Neurosciences, Inc. |
Methods and compositions for monitoring cellular processing of beta-amyloid precursor protein
|
|
US5972336A
(en)
|
1992-11-03 |
1999-10-26 |
Oravax Merieux Co. |
Urease-based vaccine against helicobacter infection
|
|
US6210671B1
(en)
|
1992-12-01 |
2001-04-03 |
Protein Design Labs, Inc. |
Humanized antibodies reactive with L-selectin
|
|
KR100307289B1
(ko)
|
1993-01-22 |
2001-12-28 |
제임스 에스. 쿼크 |
Qs-21을 함유하는 강글리오사이드-klh 접합체 백신
|
|
US5955317A
(en)
|
1993-01-25 |
1999-09-21 |
Takeda Chemical Industries, Ltd. |
Antibodies to β-amyloids or their derivatives and use thereof
|
|
EP1308461A3
(en)
|
1993-01-25 |
2004-02-11 |
Takeda Chemical Industries, Ltd. |
Antibodies to beta-amyloids or their derivatives and use thereof
|
|
US5358708A
(en)
|
1993-01-29 |
1994-10-25 |
Schering Corporation |
Stabilization of protein formulations
|
|
US5472693A
(en)
|
1993-02-16 |
1995-12-05 |
The Dow Chemical Company |
Family of anti-carcinoembryonic antigen chimeric antibodies
|
|
CA2115811A1
(en)
|
1993-02-17 |
1994-08-18 |
Claus Krebber |
A method for in vivo selection of ligand-binding proteins
|
|
CA2115900A1
(en)
|
1993-02-22 |
1994-08-23 |
Gerald W. Becker |
Pharmaceutical screens and antibodies
|
|
WO1994021680A1
(en)
|
1993-03-17 |
1994-09-29 |
The Government Of The United States Of America As |
Immunogenic chimeras comprising nucleic acid sequences encoding endoplasmic reticulum signal sequence peptides and at least one other peptide, and their uses in vaccines and disease treatments
|
|
AU6414994A
(en)
|
1993-03-18 |
1994-10-11 |
Cytimmune Sciences, Inc. |
Composition and method for reducing toxicity of biologically-active factors
|
|
WO1994021292A1
(en)
|
1993-03-23 |
1994-09-29 |
Smithkline Beecham Biologicals (S.A.) |
Vaccine compositions containing 3-o deacylated monophosphoryl lipid a
|
|
NO940913L
(no)
|
1993-03-26 |
1994-09-27 |
Bristol Myers Squibb Co |
Preparater for kontrollert frigivelse av biologisk aktiv TGF-
|
|
DK0698097T3
(da)
|
1993-04-29 |
2001-10-08 |
Unilever Nv |
Produktion af antistoffer eller (funktionaliserede) fragmenter deraf afledt af Camelidae-immunoglobuliner med tung kæde
|
|
IT1270939B
(it)
|
1993-05-11 |
1997-05-26 |
Angeletti P Ist Richerche Bio |
Procedimento per la preparazione di immunogeni e reagenti diagnostici,e immunogeni e reagenti diagnostici cosi' ottenibili.
|
|
WO1994027636A1
(en)
|
1993-05-25 |
1994-12-08 |
American Cyanamid Company |
Adjuvants for vaccines against respiratory syncytial virus
|
|
AU7043894A
(en)
|
1993-05-28 |
1994-12-20 |
Miriam Hospital, The |
Composition and method for (in vivo) imaging of amyloid deposits
|
|
EP0700445B1
(en)
|
1993-06-04 |
2002-01-23 |
Whitehead Institute For Biomedical Research |
Stress proteins and uses therefor
|
|
GR1001607B
(el)
|
1993-06-10 |
1994-06-30 |
Lucet Beatrice Yvette Michele |
Πλωτό σύστημα υποστήριξης φραγμάτων με απορροφητικά υλικά για την αντιρρυπαντική προστασία κλειστών ή ημίκλειστων υδάτινων συστημάτων από επιπλέοντες υδρογονάν?ρακες.
|
|
US5464823A
(en)
|
1993-07-20 |
1995-11-07 |
The Regents Of The University Of California |
Mammalian antibiotic peptides
|
|
DE69430246T2
(de)
|
1993-07-30 |
2002-12-12 |
Medeva Holdings Bv |
Rekombinante tetc-fusionsprotein enthaltene impfstoffzusammensetzungen
|
|
EP0664814A1
(en)
|
1993-08-18 |
1995-08-02 |
MorphoSys AG |
Lipopolysaccharide-binding and neutralizing peptides
|
|
US6538624B1
(en)
*
|
1993-08-20 |
2003-03-25 |
Seiko Epson Corporation |
Head-mounted image display apparatus
|
|
JPH09501936A
(ja)
|
1993-08-26 |
1997-02-25 |
ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア |
生物活性ペプチドをコードする裸のポリヌクレオチドを投与するための方法、組成物および装置
|
|
DK96493D0
(da)
|
1993-08-26 |
1993-08-26 |
Mouritsen Og Elsner Aps |
Fremgangsmaade til at inducere antistofresponser mod selvproteiner og autovaccine fremstillet ved fremgangsmaaden
|
|
WO1995006407A1
(en)
|
1993-08-30 |
1995-03-09 |
The Regents Of The University Of California |
Novel component of amyloid in alzheimer's disease and methods for use of same
|
|
ATE286510T1
(de)
|
1993-09-07 |
2005-01-15 |
Smithkline Beecham Corp |
In der behandlung von il4 auslösenden krankheiten nützliche rekombinante il4 antikörper
|
|
US5652334A
(en)
|
1993-09-08 |
1997-07-29 |
City Of Hope |
Method for design of substances that enhance memory and improve the quality of life
|
|
US5385887A
(en)
|
1993-09-10 |
1995-01-31 |
Genetics Institute, Inc. |
Formulations for delivery of osteogenic proteins
|
|
PT735893E
(pt)
|
1993-09-14 |
2009-03-06 |
Pharmexa Inc |
Péptidos que se ligam aos alelos pan dr para aumentar a resposta imunitária
|
|
US5470951A
(en)
|
1993-09-29 |
1995-11-28 |
City Of Hope |
Peptides for antagonizing the effects of amyloid βprotein
|
|
US5858981A
(en)
|
1993-09-30 |
1999-01-12 |
University Of Pennsylvania |
Method of inhibiting phagocytosis
|
|
ES2173130T3
(es)
|
1993-10-20 |
2002-10-16 |
Univ Duke |
Metodo de fijacion de material al peptido beta-amiloide.
|
|
AU7979094A
(en)
|
1993-10-22 |
1995-05-08 |
Genentech Inc. |
Methods and compositions for microencapsulation of adjuvants
|
|
JP3504963B2
(ja)
|
1993-10-22 |
2004-03-08 |
智靖 羅 |
抗ヒト高親和性ＩｇＥ受容体モノクローナル抗体に係るアミノ酸配列をコードするＤＮＡ断片
|
|
US5744368A
(en)
|
1993-11-04 |
1998-04-28 |
Research Foundation Of State University Of New York |
Methods for the detection of soluble amyloid β-protein (βAP) or soluble transthyretin (TTR)
|
|
JPH07132033A
(ja)
|
1993-11-12 |
1995-05-23 |
Hoechst Japan Ltd |
アルツハイマー病モデルトランスジェニック動物
|
|
US5827690A
(en)
|
1993-12-20 |
1998-10-27 |
Genzyme Transgenics Corporatiion |
Transgenic production of antibodies in milk
|
|
US5434170A
(en)
|
1993-12-23 |
1995-07-18 |
Andrulis Pharmaceuticals Corp. |
Method for treating neurocognitive disorders
|
|
GB9326253D0
(en)
|
1993-12-23 |
1994-02-23 |
Smithkline Beecham Biolog |
Vaccines
|
|
ATE278023T1
(de)
|
1994-01-27 |
2004-10-15 |
Univ Minnesota |
Nicht humane, transgenische säugetiere mit sich entwickelnder neurologischer krankheit
|
|
US5877399A
(en)
|
1994-01-27 |
1999-03-02 |
Johns Hopkins University |
Transgenic mice expressing APP-Swedish mutation develop progressive neurologic disease
|
|
US5935927A
(en)
|
1994-02-03 |
1999-08-10 |
The Picower Institute For Medical Research |
Compositions and methods for stimulating amyloid removal in amyloidogenic diseases using advanced glycosylation endproducts
|
|
AUPM411994A0
(en)
|
1994-02-25 |
1994-03-24 |
Deakin Research Limited |
Epitopes
|
|
US5795954A
(en)
|
1994-03-04 |
1998-08-18 |
Genentech, Inc. |
Factor VIIa inhibitors from Kunitz domain proteins
|
|
US6270757B1
(en)
|
1994-04-21 |
2001-08-07 |
Genetics Institute, Inc. |
Formulations for IL-11
|
|
US6372716B1
(en)
|
1994-04-26 |
2002-04-16 |
Genetics Institute, Inc. |
Formulations for factor IX
|
|
EP0760676B1
(en)
|
1994-05-25 |
2001-07-11 |
McMICHAEL, John |
Materials and methods for treatment of plaquing diseases
|
|
US5622701A
(en)
|
1994-06-14 |
1997-04-22 |
Protein Design Labs, Inc. |
Cross-reacting monoclonal antibodies specific for E- and P-selectin
|
|
US5798100A
(en)
|
1994-07-06 |
1998-08-25 |
Immunomedics, Inc. |
Multi-stage cascade boosting vaccine
|
|
US6417178B1
(en)
|
1994-07-19 |
2002-07-09 |
University Of Pittsburgh |
Amyloid binding nitrogen-linked compounds for the antemortem diagnosis of alzheimer's disease, in vivo imaging and prevention of amyloid deposits
|
|
WO1996003144A1
(en)
|
1994-07-27 |
1996-02-08 |
The Council Of The Queensland Institute Of Medical Research |
Polyepitope vaccines
|
|
GB9415379D0
(en)
|
1994-07-29 |
1994-09-21 |
Smithkline Beecham Plc |
Novel compounds
|
|
ATE370235T1
(de)
|
1994-09-16 |
2007-09-15 |
Cancer Res Fund Of Contra Cost |
Rekombinantpeptide hergeleitet vom mc3 antikörper gegen ba46, verfahren zu deren verwendung und verfahren zur humanisierung von antikörperpeptiden
|
|
US5872005A
(en)
|
1994-11-03 |
1999-02-16 |
Cell Genesys Inc. |
Packaging cell lines for adeno-associated viral vectors
|
|
US6114133A
(en)
|
1994-11-14 |
2000-09-05 |
Elan Pharmaceuticals, Inc. |
Methods for aiding in the diagnosis of Alzheimer's disease by measuring amyloid-β peptide (x-≧41)
|
|
US5589154A
(en)
|
1994-11-22 |
1996-12-31 |
Rutgers, The State University Of New Jersey |
Methods for the prevention or treatment of vascular hemorrhaging and Alzheimer's disease
|
|
US5688651A
(en)
|
1994-12-16 |
1997-11-18 |
Ramot University Authority For Applied Research And Development Ltd. |
Prevention of protein aggregation
|
|
US5612030A
(en)
|
1995-01-17 |
1997-03-18 |
University Of Kentucky Research Foundation |
Anti-idiotype monoclonal antibody 1A7 and use for the treatment of melanoma and small cell carcinoma
|
|
JP2000510813A
(ja)
|
1995-02-06 |
2000-08-22 |
ジェネテイックス・インスティテュート・インコーポレイテッド |
Ｉｌ−１２用処方
|
|
US5786180A
(en)
|
1995-02-14 |
1998-07-28 |
Bayer Corporation |
Monoclonal antibody 369.2B specific for β A4 peptide
|
|
US5624937A
(en)
|
1995-03-02 |
1997-04-29 |
Eli Lilly And Company |
Chemical compounds as inhibitors of amyloid beta protein production
|
|
US6303567B1
(en)
|
1995-03-14 |
2001-10-16 |
Praecis Pharmaceuticals, Inc . |
Modulators of β-amyloid peptide aggregation comprising D-amino acids
|
|
ATE218583T1
(de)
|
1995-03-14 |
2002-06-15 |
Praecis Pharm Inc |
Verbindungen mit aggregations-modulierenden wirkung auf das amyloid protein
|
|
US5854215A
(en)
|
1995-03-14 |
1998-12-29 |
Praecis Pharmaceuticals Incorporated |
Modulators of β-amyloid peptide aggregation
|
|
US5817626A
(en)
|
1995-03-14 |
1998-10-06 |
Praecis Pharmaceuticals Incorporated |
Modulators of beta-amyloid peptide aggregation
|
|
WO1996029421A1
(en)
|
1995-03-23 |
1996-09-26 |
Cantab Pharmaceuticals Research Limited |
Vectors for gene delivery
|
|
US6121022A
(en)
|
1995-04-14 |
2000-09-19 |
Genentech, Inc. |
Altered polypeptides with increased half-life
|
|
US5869046A
(en)
|
1995-04-14 |
1999-02-09 |
Genentech, Inc. |
Altered polypeptides with increased half-life
|
|
UA56132C2
(ru)
|
1995-04-25 |
2003-05-15 |
Смітклайн Бічем Байолоджікалс С.А. |
Композиция вакцины (варианты), способ стабилизации qs21 по отношению к гидролизу (варианты), способ приготовления вакцины
|
|
ATE274064T1
(de)
|
1995-05-23 |
2004-09-15 |
Morphosys Ag |
Multimere proteine
|
|
AU6113896A
(en)
|
1995-06-05 |
1996-12-24 |
Brigham And Women's Hospital |
Use of oral tolerance to suppress both th1 and th2 immune re sponses and to suppress antibody production
|
|
CA2221986A1
(en)
|
1995-06-07 |
1996-12-19 |
Athena Neurosciences, Inc. |
Method for identifying alzheimer's disease therapeutics using transgenic animal models
|
|
US5948763A
(en)
|
1995-06-07 |
1999-09-07 |
New York University |
Peptides and pharmaceutical compositions thereof for treatment of disorders or diseases associated with abnormal protein folding into amyloid or amyloid-like deposits
|
|
US5910427A
(en)
|
1995-06-22 |
1999-06-08 |
La Jolla Institute For Allergy And Immunology |
Antigen non-specific glycosylation inhibiting factor derivatives
|
|
ES2174027T3
(es)
|
1995-06-30 |
2002-11-01 |
American Cyanamid Co |
Composiciones estables que contienen macrolidos y macrolidos combinados con unas vacunas.
|
|
CA2226255A1
(en)
|
1995-07-07 |
1997-01-30 |
Darwin Molecular Corporation |
Chromosome 1 gene and gene products related to alzheimer's disease
|
|
US6267958B1
(en)
|
1995-07-27 |
2001-07-31 |
Genentech, Inc. |
Protein formulation
|
|
US6685940B2
(en)
|
1995-07-27 |
2004-02-03 |
Genentech, Inc. |
Protein formulation
|
|
AUPN443995A0
(en)
|
1995-07-27 |
1995-08-17 |
Csl Limited |
Papillomavirus polyprotein
|
|
PT859841E
(pt)
|
1995-08-18 |
2002-11-29 |
Morphosys Ag |
Bibliotecas de proteinas/ (poli) peptidos
|
|
AU6898996A
(en)
|
1995-08-21 |
1997-03-12 |
Cytrx Corporation |
Compositions and methods for growth promotion
|
|
EP0852011B1
(en)
|
1995-09-14 |
2004-03-31 |
The Regents of the University of California |
ANTIBODIES SPECIFIC FOR NATIVE PrP?Sc
|
|
US5731284A
(en)
|
1995-09-28 |
1998-03-24 |
Amgen Inc. |
Method for treating Alzheimer's disease using glial line-derived neurotrophic factor (GDNF) protein product
|
|
EP0854919A1
(en)
|
1995-10-10 |
1998-07-29 |
Novartis AG |
Melanoma-associated protein
|
|
US5985242A
(en)
|
1995-10-27 |
1999-11-16 |
Praecis Pharmaceuticals, Inc. |
Modulators of β-amyloid peptide aggregation comprising D-amino acids
|
|
US5750361A
(en)
|
1995-11-02 |
1998-05-12 |
The Regents Of The University Of California |
Formation and use of prion protein (PRP) complexes
|
|
EP0859959B1
(en)
|
1995-11-10 |
2003-08-06 |
ELAN CORPORATION, Plc |
Peptides which enhance transport across tissues and methods of identifying and using the same
|
|
WO1997018855A1
(en)
|
1995-11-21 |
1997-05-29 |
Eduard Naumovich Lerner |
Device for enhanced delivery of biologically active substances and compounds in an organism
|
|
EP0866805A1
(en)
|
1995-12-12 |
1998-09-30 |
Karolinska Innovations AB |
PEPTIDE BINDING THE KLVFF-SEQUENCE OF AMYLOID $g(b)
|
|
JPH09178743A
(ja)
|
1995-12-27 |
1997-07-11 |
Oriental Yeast Co Ltd |
可溶性ａｐｐの定量法
|
|
US5723125A
(en)
|
1995-12-28 |
1998-03-03 |
Tanox Biosystems, Inc. |
Hybrid with interferon-alpha and an immunoglobulin Fc linked through a non-immunogenic peptide
|
|
US6015662A
(en)
|
1996-01-23 |
2000-01-18 |
Abbott Laboratories |
Reagents for use as calibrators and controls
|
|
ZA97452B
(en)
|
1996-01-25 |
1997-08-15 |
Trinity College Dublin |
Streptococcus equi vaccine.
|
|
US5770700A
(en)
|
1996-01-25 |
1998-06-23 |
Genetics Institute, Inc. |
Liquid factor IX formulations
|
|
JPH09208485A
(ja)
|
1996-01-31 |
1997-08-12 |
Teijin Ltd |
ペプチド・蛋白質性薬物の水難溶性組成物
|
|
US6096313A
(en)
|
1996-02-09 |
2000-08-01 |
Ludwig Institute For Cancer Research |
Compositions containing immunogenic molecules and granulocyte-macrophage colony stimulating factor, as an adjuvant
|
|
WO1997032017A1
(en)
|
1996-02-26 |
1997-09-04 |
Morphosys Gesellschaft Für Proteinoptimierung Mbh |
Novel method for the identification of nucleic acid sequences encoding two or more interacting (poly)peptides
|
|
US6150091A
(en)
|
1996-03-06 |
2000-11-21 |
Baylor College Of Medicine |
Direct molecular diagnosis of Friedreich ataxia
|
|
KR100266924B1
(ko)
|
1996-03-23 |
2000-09-15 |
무따이 마사히꼬 |
파상풍독소의 기능적 단편 항원 및 파상풍 백신
|
|
HUP9902438A3
(en)
|
1996-03-29 |
2000-03-28 |
Bayer Ag |
Parapoxvirus vectors
|
|
US5837829A
(en)
|
1996-04-02 |
1998-11-17 |
Abbott Laboratories |
9-oximesilyl erythromycin a derivatives
|
|
EP0954324A4
(en)
|
1996-04-03 |
2000-11-02 |
Anergen Inc |
CYCLIC PEPTID VACCINES FOR DIABETES TREATMENT AND PREVENTION
|
|
AU735733B2
(en)
|
1996-04-19 |
2001-07-12 |
Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The |
Antigenically reactive regions of the hepatitis A virus polyprotein
|
|
US6284533B1
(en)
|
1996-05-01 |
2001-09-04 |
Avant Immunotherapeutics, Inc. |
Plasmid-based vaccine for treating atherosclerosis
|
|
JP2000516452A
(ja)
|
1996-07-16 |
2000-12-12 |
プリュックテュン，アンドレアス |
可溶性が増大した免疫グロブリンスーパーファミリードメインおよびフラグメント
|
|
WO1998004720A1
(en)
|
1996-07-26 |
1998-02-05 |
Sloan-Kettering Institute For Cancer Research |
Method and reagents for genetic immunization
|
|
US7147851B1
(en)
|
1996-08-15 |
2006-12-12 |
Millennium Pharmaceuticals, Inc. |
Humanized immunoglobulin reactive with α4β7 integrin
|
|
CA2183901A1
(en)
|
1996-08-22 |
1998-02-23 |
Johanna E. Bergmann |
Targets for therapy and diagnosis of alzheimer's disease and down syndrome in humans
|
|
GB9617616D0
(en)
|
1996-08-22 |
1996-10-02 |
Osteometer Biotech As |
Assaying protein fragments in body fluids
|
|
AU741199B2
(en)
|
1996-08-27 |
2001-11-22 |
Praecis Pharmaceuticals Incorporated |
Modulators of beta-amyloid peptide aggregation comprising D-amino acids
|
|
US6057367A
(en)
|
1996-08-30 |
2000-05-02 |
Duke University |
Manipulating nitrosative stress to kill pathologic microbes, pathologic helminths and pathologically proliferating cells or to upregulate nitrosative stress defenses
|
|
US6797495B2
(en)
|
1996-11-05 |
2004-09-28 |
The Regents Of The University Of California |
Somatic cells with ablated PrP gene and methods of use
|
|
US6022859A
(en)
|
1996-11-15 |
2000-02-08 |
Wisconsin Alumni Research Foundation |
Inhibitors of β-amyloid toxicity
|
|
WO1998022120A1
(en)
|
1996-11-19 |
1998-05-28 |
The Wistar Institute Of Anatomy & Biology |
Diagnostic and therapeutic reagents for alzheimer's disease
|
|
AUPO390396A0
(en)
|
1996-11-29 |
1996-12-19 |
Csl Limited |
Novel promiscuous T helper cell epitopes
|
|
US6962984B2
(en)
|
1996-12-05 |
2005-11-08 |
Nihon University |
IgA nephropathy-related DNA
|
|
US6218506B1
(en)
|
1997-02-05 |
2001-04-17 |
Northwestern University |
Amyloid β protein (globular assembly and uses thereof)
|
|
US20030068316A1
(en)
|
1997-02-05 |
2003-04-10 |
Klein William L. |
Anti-ADDL antibodies and uses thereof
|
|
WO1998039303A1
(en)
|
1997-03-03 |
1998-09-11 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Small molecules useful in the treatment of inflammatory disease
|
|
US6277375B1
(en)
|
1997-03-03 |
2001-08-21 |
Board Of Regents, The University Of Texas System |
Immunoglobulin-like domains with increased half-lives
|
|
US5798102A
(en)
|
1997-03-04 |
1998-08-25 |
Milkhaus Laboratory, Inc. |
Treatment of cardiomyopathy
|
|
DK1005368T3
(da)
|
1997-03-10 |
2010-01-04 |
Ottawa Hospital Res Inst |
Anvendelse af nukleinsyrer, der indeholder ikke-metyleret CpG dinukleotid i kombination med alun som hjælpestoffer
|
|
US6057098A
(en)
|
1997-04-04 |
2000-05-02 |
Biosite Diagnostics, Inc. |
Polyvalent display libraries
|
|
US8173127B2
(en)
|
1997-04-09 |
2012-05-08 |
Intellect Neurosciences, Inc. |
Specific antibodies to amyloid beta peptide, pharmaceutical compositions and methods of use thereof
|
|
US20020086847A1
(en)
|
1997-04-09 |
2002-07-04 |
Mindset Biopharmaceuticals (Usa) |
Recombinant antibodies specific for beta-amyloid ends, DNA encoding and methods of use thereof
|
|
EP2006303A1
(en)
|
1997-04-09 |
2008-12-24 |
Intellect Neurosciences, Inc. |
Recombinant antibodies specific for Beta-Amyloid ends, DNA encoding and methods of use thereof
|
|
US7118750B1
(en)
|
1997-04-15 |
2006-10-10 |
Pharmexa A/S |
Modified TNF-alpha molecules, DNA encoding such and vaccines comprising such modified TNF-alpha and DNA
|
|
US6787319B2
(en)
|
1997-04-16 |
2004-09-07 |
American Home Products Corp. |
β-amyloid peptide-binding proteins and polynucleotides encoding the same
|
|
US6339068B1
(en)
|
1997-05-20 |
2002-01-15 |
University Of Iowa Research Foundation |
Vectors and methods for immunization or therapeutic protocols
|
|
CA2292730C
(en)
|
1997-06-13 |
2008-09-16 |
Genentech, Inc. |
Stabilized antibody formulation
|
|
AU8269898A
(en)
|
1997-06-27 |
1999-01-19 |
Regents Of The University Of California, The |
Drug targeting of a peptide radiopharmaceutical through the primate blood-brain barrier in vivo with a monoclonal antibody to the human insulin receptor
|
|
IT1293511B1
(it)
|
1997-07-30 |
1999-03-01 |
Gentili Ist Spa |
Anticorpi monoclonali catalitici ad attivita' proteasica per la lisi selettiva della componente proteica di placche e aggregati correlati
|
|
IT1293510B1
(it)
|
1997-07-30 |
1999-03-01 |
Gentili Ist Spa |
Anticorpi monoclonali catalitici per la trasformazione in vivo di profarmaci di corticosteroidi
|
|
ATE491721T1
(de)
|
1997-08-01 |
2011-01-15 |
Max Planck Gesellschaft |
Zusammensetzung und verfahren zum nachweis von krankheiten in zusammenhang mit der bildung von amyloid-ähnlichen fibrillen oder protein- aggregaten
|
|
WO1999006587A2
(en)
|
1997-08-01 |
1999-02-11 |
Morphosys Ag |
Novel method and phage for the identification of nucleic acid sequences encoding members of a multimeric (poly)peptide complex
|
|
ATE435661T1
(de)
|
1997-08-29 |
2009-07-15 |
Antigenics Inc |
Adjuvant qs-21 enthaltende zusammensetzungen mit polysorbate oder cyclodextrin als hilfsmittel
|
|
US6175057B1
(en)
|
1997-10-08 |
2001-01-16 |
The Regents Of The University Of California |
Transgenic mouse model of alzheimer's disease and cerebral amyloid angiopathy
|
|
US6118044A
(en)
|
1997-11-14 |
2000-09-12 |
Sankyo Company, Limited |
Transgenic animal allergy models and methods for their use
|
|
US6923964B1
(en)
|
1997-12-02 |
2005-08-02 |
Neuralab Limited |
Active immunization of AScr for prion disorders
|
|
TWI239847B
(en)
|
1997-12-02 |
2005-09-21 |
Elan Pharm Inc |
N-terminal fragment of Abeta peptide and an adjuvant for preventing and treating amyloidogenic disease
|
|
US6710226B1
(en)
|
1997-12-02 |
2004-03-23 |
Neuralab Limited |
Transgenic mouse assay to determine the effect of Aβ antibodies and Aβ Fragments on alzheimer's disease characteristics
|
|
US7588766B1
(en)
*
|
2000-05-26 |
2009-09-15 |
Elan Pharma International Limited |
Treatment of amyloidogenic disease
|
|
US7964192B1
(en)
|
1997-12-02 |
2011-06-21 |
Janssen Alzheimer Immunotherapy |
Prevention and treatment of amyloidgenic disease
|
|
US6913745B1
(en)
*
|
1997-12-02 |
2005-07-05 |
Neuralab Limited |
Passive immunization of Alzheimer's disease
|
|
US7179892B2
(en)
|
2000-12-06 |
2007-02-20 |
Neuralab Limited |
Humanized antibodies that recognize beta amyloid peptide
|
|
US6905686B1
(en)
|
1997-12-02 |
2005-06-14 |
Neuralab Limited |
Active immunization for treatment of alzheimer's disease
|
|
US6761888B1
(en)
*
|
2000-05-26 |
2004-07-13 |
Neuralab Limited |
Passive immunization treatment of Alzheimer's disease
|
|
US7790856B2
(en)
|
1998-04-07 |
2010-09-07 |
Janssen Alzheimer Immunotherapy |
Humanized antibodies that recognize beta amyloid peptide
|
|
US20080050367A1
(en)
*
|
1998-04-07 |
2008-02-28 |
Guriq Basi |
Humanized antibodies that recognize beta amyloid peptide
|
|
US6787523B1
(en)
*
|
1997-12-02 |
2004-09-07 |
Neuralab Limited |
Prevention and treatment of amyloidogenic disease
|
|
US6750324B1
(en)
*
|
1997-12-02 |
2004-06-15 |
Neuralab Limited |
Humanized and chimeric N-terminal amyloid beta-antibodies
|
|
IL136251A0
(en)
|
1997-12-03 |
2001-05-20 |
Fujisawa Pharmaceutical Co |
Soft pellet drug composition and methods for the preparation thereof
|
|
DE69831971T2
(de)
|
1997-12-03 |
2006-07-06 |
Neuralab Ltd., Flatts |
Unterdrückung von veränderungen in zusammenhang mit beta-amyloid bei alzheimer
|
|
FR2777015B3
(fr)
|
1998-02-23 |
2000-09-15 |
Financ De Biotechnologie |
Procede et moyens pour l'obtention de modeles cellulaires et animaux de maladies neurodegeneratives
|
|
US6528624B1
(en)
|
1998-04-02 |
2003-03-04 |
Genentech, Inc. |
Polypeptide variants
|
|
US6194551B1
(en)
|
1998-04-02 |
2001-02-27 |
Genentech, Inc. |
Polypeptide variants
|
|
US20050059802A1
(en)
|
1998-04-07 |
2005-03-17 |
Neuralab Ltd |
Prevention and treatment of amyloidogenic disease
|
|
US20050059591A1
(en)
|
1998-04-07 |
2005-03-17 |
Neuralab Limited |
Prevention and treatment of amyloidogenic disease
|
|
ES2230848T3
(es)
|
1998-04-28 |
2005-05-01 |
Smithkline Beecham Corporation |
Anticuerpos monoclonales con inmunogenicidad reducida.
|
|
NO314086B1
(no)
|
1998-05-08 |
2003-01-27 |
Gemvax As |
Peptider og farmasöytiske sammensetninger inneholdende disse, nukleinsyresekvenser som koder for slike peptider, plasmider og virusvektoreromfattende slike DNA-sekvenser samt anvendelse av disse for fremstilling avfarmasöytiske preparater til
|
|
GB9809951D0
(en)
|
1998-05-08 |
1998-07-08 |
Univ Cambridge Tech |
Binding molecules
|
|
CA2328612A1
(en)
|
1998-05-19 |
1999-11-25 |
Yeda Research And Development Co., Ltd. |
Activated t cells, nervous system-specific antigens and their uses
|
|
WO1999060024A1
(en)
|
1998-05-21 |
1999-11-25 |
The University Of Tennessee Research Corporation |
Methods for amyloid removal using anti-amyloid antibodies
|
|
US20030147882A1
(en)
|
1998-05-21 |
2003-08-07 |
Alan Solomon |
Methods for amyloid removal using anti-amyloid antibodies
|
|
US6432710B1
(en)
|
1998-05-22 |
2002-08-13 |
Isolagen Technologies, Inc. |
Compositions for regenerating tissue that has deteriorated, and methods for using such compositions
|
|
US6727349B1
(en)
|
1998-07-23 |
2004-04-27 |
Millennium Pharmaceuticals, Inc. |
Recombinant anti-CCR2 antibodies and methods of use therefor
|
|
WO2000020027A2
(en)
|
1998-10-05 |
2000-04-13 |
M & E Biotech A/S |
Methods for therapeutic vaccination
|
|
CA2354862A1
(en)
|
1998-10-19 |
2000-04-27 |
Yeda Research And Development Co. Ltd. |
Treatment of systemic lupus erythematosus by down-regulating the autoimmune response to autoantigens
|
|
US7112661B1
(en)
|
1998-10-30 |
2006-09-26 |
The Research Foundation Of State University Of New York |
Variable heavy chain and variable light chain regions of antibodies to human platelet glycoprotein Ib alpha
|
|
GB2348203B
(en)
|
1998-11-04 |
2002-06-19 |
Imp College Innovations Ltd |
Solube beta-forms of prion proteins, methods of preparation and use
|
|
CA2355894C
(en)
|
1999-01-19 |
2006-10-10 |
Pharmacia & Upjohn Company |
Gamma-irradiation sterilized polyethylene packaging
|
|
EP1146898A1
(en)
|
1999-01-22 |
2001-10-24 |
Matthew John During |
Vaccine-mediated treatment of neurological disorders
|
|
KR100452064B1
(ko)
|
1999-02-05 |
2004-10-08 |
삼성전자주식회사 |
디지털 영상 처리 장치
|
|
US7629311B2
(en)
*
|
1999-02-24 |
2009-12-08 |
Edward Lewis Tobinick |
Methods to facilitate transmission of large molecules across the blood-brain, blood-eye, and blood-nerve barriers
|
|
US20040038317A1
(en)
|
1999-03-15 |
2004-02-26 |
Kalobios, Inc. |
Breakpoint fusion fragment complementation system
|
|
US7282570B2
(en)
|
1999-04-20 |
2007-10-16 |
Genentech, Inc. |
Compositions and methods for the treatment of immune related diseases
|
|
CA2388092A1
(en)
|
1999-05-05 |
2000-11-16 |
Neurochem, Inc. |
Stereoselective antifibrillogenic peptides and peptidomimetics thereof
|
|
US6787637B1
(en)
|
1999-05-28 |
2004-09-07 |
Neuralab Limited |
N-Terminal amyloid-β antibodies
|
|
UA81216C2
(en)
|
1999-06-01 |
2007-12-25 |
|
Prevention and treatment of amyloid disease
|
|
PE20010212A1
(es)
|
1999-06-01 |
2001-02-22 |
Neuralab Ltd |
Composiciones del peptido a-beta y procesos para producir las mismas
|
|
US7510824B2
(en)
*
|
1999-06-02 |
2009-03-31 |
Nono Inc. |
Method of screening peptides useful in treating traumatic injury to the brain or spinal cord
|
|
AU780474B2
(en)
|
1999-06-16 |
2005-03-24 |
Boston Biomedical Research Institute Incorporated |
Immunological control of beta-amyloid levels in vivo
|
|
EP1192462A1
(en)
|
1999-07-01 |
2002-04-03 |
Scios Inc. |
Prevention and treatment of amyloid-associated disorders
|
|
MXPA02000525A
(es)
|
1999-07-15 |
2005-07-01 |
Inst Genetics Llc |
Formulaciones de il-11.
|
|
AU6524500A
(en)
|
1999-08-04 |
2001-03-05 |
Northwestern University |
Amyloid beta protein (globular assembly and uses thereof)
|
|
WO2001018169A2
(en)
|
1999-09-03 |
2001-03-15 |
Ramot University Authority For Applied Research & Industrial Development Ltd. |
Agents and compositions and methods for diagnostic and/or treating or preventing plaque forming diseases
|
|
US6294171B2
(en)
|
1999-09-14 |
2001-09-25 |
Milkhaus Laboratory, Inc. |
Methods for treating disease states comprising administration of low levels of antibodies
|
|
US6824780B1
(en)
|
1999-10-29 |
2004-11-30 |
Genentech, Inc. |
Anti-tumor antibody compositions and methods of use
|
|
NZ540564A
(en)
|
1999-11-29 |
2007-04-27 |
Neurochem Int Ltd |
Vaccine for the prevention and treatment of Alzheimer's and amyloid related diseases
|
|
US20020094335A1
(en)
|
1999-11-29 |
2002-07-18 |
Robert Chalifour |
Vaccine for the prevention and treatment of alzheimer's and amyloid related diseases
|
|
ES2275570T3
(es)
|
1999-12-08 |
2007-06-16 |
Intellect Neurosciences, Inc. |
Peptidos amiloides beta quimericos.
|
|
US6399314B1
(en)
|
1999-12-29 |
2002-06-04 |
American Cyanamid Company |
Methods of detection of amyloidogenic proteins
|
|
WO2001062284A2
(en)
|
2000-02-21 |
2001-08-30 |
Pharmexa A/S |
Novel method for down-regulation of amyloid
|
|
MXPA02007796A
(es)
|
2000-02-21 |
2003-12-08 |
Pharmexa As |
Metodo novedoso para la disminucion de cuerpos amiloides.
|
|
PL210157B1
(pl)
|
2000-02-24 |
2011-12-30 |
Lilly Co Eli |
Humanizowane przeciwciało lub jego fragment, kwas polinukleinowy, wektor ekspresyjny do ekspresji przeciwciała lub jego fragmentu, komórka transfekowana wektorem ekspresyjnym, kompozycja farmaceutyczna i zastosowanie humanizowanego przeciwciała lub jego fragmentu do leczenia choroby Alzheimera
|
|
US7485616B2
(en)
|
2000-04-05 |
2009-02-03 |
University Of Tennessee Research Foundation |
Methods of investigating, diagnosing, and treating amyloidosis
|
|
WO2001078777A2
(en)
|
2000-04-13 |
2001-10-25 |
Mossman, Sally |
Immunostimulant compositions comprising an aminoalkyl glucosaminide phosphate and qs-21
|
|
AU7487301A
(en)
|
2000-05-22 |
2001-12-03 |
Univ New York |
Synthetic immunogenic but non-amyloidogenic peptides homologous to amyloid beta for induction of an immune response to amyloid beta and amyloid deposits
|
|
AU6882801A
(en)
|
2000-06-28 |
2002-01-08 |
Prana Biotechnology Ltd |
Neurotoxic oligomers
|
|
CA2414772C
(en)
|
2000-07-07 |
2011-06-28 |
Jan Naslund |
Prevention and treatment of alzheimer's disease
|
|
EP1172378A1
(en)
|
2000-07-12 |
2002-01-16 |
Richard Dr. Dodel |
Human beta-amyloid antibody and use thereof for treatment of alzheimer's disease
|
|
US20020009445A1
(en)
|
2000-07-12 |
2002-01-24 |
Yansheng Du |
Human beta-amyloid antibody and use thereof for treatment of alzheimer's disease
|
|
DE10038237A1
(de)
|
2000-08-04 |
2002-02-14 |
Aventis Res & Tech Gmbh & Co |
Verfahren zum Nachweis von Mutationen in Nucleotidsequenzen
|
|
US20030092145A1
(en)
|
2000-08-24 |
2003-05-15 |
Vic Jira |
Viral vaccine composition, process, and methods of use
|
|
EP1317479B1
(en)
|
2000-09-06 |
2009-09-02 |
Aventis Pharma S.A. |
Methods and compositions for diseases associated with amyloidosis
|
|
IT1319277B1
(it)
|
2000-10-24 |
2003-09-26 |
Chiesi Farma Spa |
Proteine di fusione utili per il trattamento di immunizzazione dellamalattia di alzheimer.
|
|
IL139308A0
(en)
|
2000-10-26 |
2001-11-25 |
Marikovsky Moshe |
Peptides from amyloid precursor protein which inhibit tumor growth and metastasis
|
|
US7668586B2
(en)
|
2000-11-02 |
2010-02-23 |
Cornell Research Foundation, Inc. |
In vivo multiphoton diagnostic detection and imaging of a neurodegenerative disease
|
|
DK1346041T3
(da)
|
2000-11-27 |
2007-07-02 |
Praecis Pharm Inc |
Terapeutiske midler og fremgangsmåder til anvendelse deraf til behandling af en amyloidogen sygdom
|
|
PE20020574A1
(es)
*
|
2000-12-06 |
2002-07-02 |
Wyeth Corp |
Anticuerpos humanizados que reconocen el peptido amiloideo beta
|
|
US7700751B2
(en)
|
2000-12-06 |
2010-04-20 |
Janssen Alzheimer Immunotherapy |
Humanized antibodies that recognize β-amyloid peptide
|
|
US6900036B2
(en)
|
2000-12-27 |
2005-05-31 |
University Of Texas Health Science Center Houston |
Prion isomers, methods of making, methods of using, and compositions and products comprising prion isomers
|
|
WO2002059621A2
(en)
|
2001-01-24 |
2002-08-01 |
Bayer Corporation |
Regulation of transthyretin to treat obesity
|
|
EP1251138B1
(en)
|
2001-04-19 |
2006-07-26 |
Hermann Dr. Schätzl |
Prion protein dimers useful for vaccination
|
|
ATE420114T1
(de)
|
2001-04-30 |
2009-01-15 |
Lilly Co Eli |
Humanisierte antikörper die das beta-amyloid peptid erkennen& x9;
|
|
AU2002257162A1
(en)
|
2001-04-30 |
2002-11-11 |
Eli Lilly And Company |
Humanized antibodies
|
|
US6906169B2
(en)
|
2001-05-25 |
2005-06-14 |
United Biomedical, Inc. |
Immunogenic peptide composition comprising measles virus Fprotein Thelper cell epitope (MUFThl-16) and N-terminus of β-amyloid peptide
|
|
GB0113179D0
(en)
|
2001-05-31 |
2001-07-25 |
Novartis Ag |
Organic compounds
|
|
US20020197258A1
(en)
|
2001-06-22 |
2002-12-26 |
Ghanbari Hossein A. |
Compositions and methods for preventing protein aggregation in neurodegenerative diseases
|
|
JP4317010B2
(ja)
|
2001-07-25 |
2009-08-19 |
ピーディーエル バイオファーマ，インコーポレイティド |
ＩｇＧ抗体の安定な凍結乾燥医薬製剤
|
|
US20030135035A1
(en)
|
2001-08-09 |
2003-07-17 |
Mark Shannon |
Human ZZAP1 protein
|
|
CA2451998A1
(en)
|
2001-08-17 |
2003-02-27 |
Eli Lilly And Company |
Anti-a.beta. antibodies
|
|
US20040241164A1
(en)
|
2001-08-17 |
2004-12-02 |
Bales Kelly Renee |
Use of antibodies having high affinity for soluble ab to treat conditions and diseases related to ass
|
|
AU2002324468A1
(en)
|
2001-08-17 |
2003-03-03 |
Eli Lilly And Company |
Rapid improvement of cognition in conditions related to abeta
|
|
US20030082191A1
(en)
|
2001-08-29 |
2003-05-01 |
Poduslo Joseph F. |
Treatment for central nervous system disorders
|
|
EP1435774B1
(en)
*
|
2001-09-10 |
2010-08-25 |
AntiCancer, Inc. |
Enhanced resolution of tumor metastasis
|
|
US6907297B2
(en)
|
2001-09-28 |
2005-06-14 |
Ethicon, Inc. |
Expandable intracardiac return electrode and method of use
|
|
US7781413B2
(en)
|
2001-10-31 |
2010-08-24 |
Board Of Regents, The University Of Texas System |
SEMA3B inhibits tumor growth and induces apoptosis in cancer cells
|
|
AU2002363339B2
(en)
|
2001-11-08 |
2008-02-07 |
Abbvie Biotechnology Ltd |
Stable liquid pharmaceutical formulation of IGG antibodies
|
|
CA2466841A1
(en)
|
2001-11-21 |
2003-06-05 |
New York University |
Synthetic immunogenic but non-deposit-forming polypeptides and peptides homologous to amyloid .beta., prion protein, amylin, .alpha.-synuclein, or polyglutamine repeats for induction of an immune response thereto
|
|
AU2002366355A1
(en)
|
2001-12-17 |
2003-06-30 |
New York State Office Of Mental Health |
SEQUESTRATION OF ABeta IN THE PERIPHERY IN THE ABSENCE OF IMMUNOMODULATING AGENT AS A THERAPEUTIC APPROACH FOR THE TREATMENT OR PREVENTION OF BETA-AMYLOID RELATED DISEASES
|
|
US7335478B2
(en)
|
2002-04-18 |
2008-02-26 |
Kalobios Pharmaceuticals, Inc. |
Reactivation-based molecular interaction sensors
|
|
US7432063B2
(en)
|
2002-02-14 |
2008-10-07 |
Kalobios Pharmaceuticals, Inc. |
Methods for affinity maturation
|
|
US20030157579A1
(en)
|
2002-02-14 |
2003-08-21 |
Kalobios, Inc. |
Molecular sensors activated by disinhibition
|
|
AR038568A1
(es)
|
2002-02-20 |
2005-01-19 |
Hoffmann La Roche |
Anticuerpos anti-a beta y su uso
|
|
US20040001828A1
(en)
|
2002-02-21 |
2004-01-01 |
Joseph Tuscano |
Treatment methods using anti-CD22 antibodies
|
|
MY139983A
(en)
*
|
2002-03-12 |
2009-11-30 |
Janssen Alzheimer Immunotherap |
Humanized antibodies that recognize beta amyloid peptide
|
|
US20040038304A1
(en)
|
2002-03-28 |
2004-02-26 |
Gala Design, Inc. |
Antibody libraries
|
|
US7132100B2
(en)
|
2002-06-14 |
2006-11-07 |
Medimmune, Inc. |
Stabilized liquid anti-RSV antibody formulations
|
|
JP4644488B2
(ja)
|
2002-07-19 |
2011-03-02 |
サイトス・バイオテクノロジー・アクチェンゲゼルシャフト |
アミロイドベータ１−６抗原アレイを含むワクチン組成物
|
|
EP1523499A2
(en)
|
2002-07-24 |
2005-04-20 |
Innogenetics N.V. |
Fragments of beta-amyloid as targets for vaccination against alzheimer disease
|
|
US6827524B2
(en)
*
|
2002-07-26 |
2004-12-07 |
Ingersoll-Rand Company |
Controller for a compacting vehicle wetting system
|
|
BR0313588A
(pt)
*
|
2002-08-07 |
2005-07-12 |
Novartis Ag |
Métodos para o tratamento da demência com base em apo e genótipo
|
|
US6802134B2
(en)
|
2002-08-09 |
2004-10-12 |
Patrick J. Allen |
Tapered sliding dovetail tool and kit including such tool
|
|
WO2004029629A1
(en)
|
2002-09-27 |
2004-04-08 |
Janssen Pharmaceutica N.V. |
N-11 truncated amyloid-beta nomoclonal antibodies, compositions, methods and uses
|
|
JP2006508072A
(ja)
|
2002-10-01 |
2006-03-09 |
ノースウエスタン ユニバーシティ |
アミロイドベータ由来拡散性リガンド（ＡＤＤＬｓ）、ＡＤＤＬ代替物、ＡＤＤＬ結合性分子、およびそれらの使用
|
|
PL377769A1
(pl)
|
2002-10-09 |
2006-02-20 |
Rinat Neuroscience Corp. |
Sposób leczenia choroby Alzheimera z zastosowaniem przeciwciał skierowanych przeciw peptydowi beta amyloidu i ich kompozycje
|
|
US7365168B2
(en)
|
2002-10-15 |
2008-04-29 |
Pdl Biopharma, Inc. |
Alteration of FcRn binding affinities or serum half-lives of antibodies by mutagenesis
|
|
US20060019850A1
(en)
*
|
2002-10-31 |
2006-01-26 |
Korzenski Michael B |
Removal of particle contamination on a patterned silicon/silicon dioxide using dense fluid/chemical formulations
|
|
FR2846667B1
(fr)
|
2002-11-06 |
2004-12-31 |
Pasteur Institut |
Fragments variables d'anticorps de camelides a chaine unique diriges contre le peptide beta-amyloide 1-42 et leurs applications pour le diagnostic et le traitement des maladies neuroagregatives
|
|
AU2003293543A1
(en)
|
2002-12-13 |
2004-07-09 |
Abgenix, Inc. |
System and method for stabilizing antibodies with histidine
|
|
US6787129B1
(en)
|
2003-01-13 |
2004-09-07 |
Zenitech Llc |
Castor polyester as gloss agents in anionic systems
|
|
CA2513722A1
(en)
|
2003-02-01 |
2004-08-19 |
Neuralab Limited |
Active immunization to generate antibodies to soluble a-beta
|
|
ATE468886T1
(de)
|
2003-02-10 |
2010-06-15 |
Applied Molecular Evolution |
Abeta-bindende moleküle
|
|
US20050008625A1
(en)
|
2003-02-13 |
2005-01-13 |
Kalobios, Inc. |
Antibody affinity engineering by serial epitope-guided complementarity replacement
|
|
US8663650B2
(en)
|
2003-02-21 |
2014-03-04 |
Ac Immune Sa |
Methods and compositions comprising supramolecular constructs
|
|
US20040242845A1
(en)
|
2003-02-21 |
2004-12-02 |
Nicolau Yves Claude |
Methods and compositions comprising supramolecular antigenic constructs and antibodies elicited against them
|
|
US20050129695A1
(en)
|
2003-03-28 |
2005-06-16 |
Marc Mercken |
Anti-amyloid antibodies, compositions, methods and uses
|
|
KR101208291B1
(ko)
|
2003-04-04 |
2012-12-05 |
노파르티스 아게 |
고농도 항체 및 단백질 제형
|
|
EP1480041A1
(en)
|
2003-05-22 |
2004-11-24 |
Innogenetics N.V. |
Method for the prediction, diagnosis and differential diagnosis of Alzheimer's disease
|
|
TWI306458B
(en)
*
|
2003-05-30 |
2009-02-21 |
Elan Pharma Int Ltd |
Humanized antibodies that recognize beta amyloid peptide
|
|
CA2527694C
(en)
|
2003-05-30 |
2015-07-14 |
Hendricus Renerus Jacobus Mattheus Hoogenboom |
Fab library for the preparation of anti vegf and anti rabies virus fabs
|
|
US20060182321A1
(en)
|
2003-07-07 |
2006-08-17 |
Agency For Science, Technology And Research |
Method and apparatus for extracting third ventricle information
|
|
WO2005014041A2
(en)
|
2003-07-24 |
2005-02-17 |
Novartis Ag |
Use of an amyloid beta dna vaccine for the treatment and/or prevention of amyloid diseases
|
|
US20050123553A1
(en)
|
2003-07-30 |
2005-06-09 |
Alon Monsonego |
Amyloid beta-peptide and methods of use
|
|
WO2005026211A2
(en)
|
2003-09-05 |
2005-03-24 |
Eli Lilly And Company |
Anti-ghrelin antibodies
|
|
CA2445743A1
(en)
|
2003-10-08 |
2005-04-08 |
The University Of British Columbia |
Methods for modulating neuronal responses
|
|
WO2005035753A1
(ja)
|
2003-10-10 |
2005-04-21 |
Chugai Seiyaku Kabushiki Kaisha |
機能蛋白質を代替する二重特異性抗体
|
|
CA2549552A1
(en)
|
2003-12-17 |
2005-06-30 |
Elan Pharmaceuticals, Inc. |
A.beta. immunogenic peptide carrier conjugates and methods of producing same
|
|
EP1701968B1
(en)
|
2003-12-17 |
2015-06-03 |
Wyeth LLC |
Immunogenic peptide carrier conjugates and methods of producing same
|
|
ATE546531T1
(de)
|
2003-12-31 |
2012-03-15 |
Kalobios Inc |
Transaktivierungssystem für säugerzellen
|
|
AU2005207003C1
(en)
|
2004-01-20 |
2013-06-13 |
Humanigen, Inc. |
Antibody specificity transfer using minimal essential binding determinants
|
|
US20050214222A1
(en)
|
2004-02-13 |
2005-09-29 |
Mckinnon Stuart J |
In vivo imaging of amyloid plaques in glaucoma using intravenous injectable dyes
|
|
US7807157B2
(en)
|
2004-02-20 |
2010-10-05 |
Intellect Neurosciences Inc. |
Monoclonal antibodies and use thereof
|
|
PL2653465T3
(pl)
|
2004-03-15 |
2017-01-31 |
Janssen Pharmaceutica Nv |
Modulatory receptora opioidowego
|
|
FR2871633A1
(fr)
|
2004-06-10 |
2005-12-16 |
France Telecom |
Procede de reduction du bruit de phase lors de la reception d'un signal ofdm, recepteur, programme et support
|
|
SE0401601D0
(sv)
|
2004-06-21 |
2004-06-21 |
Bioarctic Neuroscience Ab |
Protofibril specific antibodies and uses thereof
|
|
ES2427963T3
(es)
|
2004-07-02 |
2013-11-05 |
University Of Pittsburgh - Of The Commonwealth System Of Higher Education |
Uso de derivados de tioflavina radiomarcados en formación de imágenes de amiloide para evaluación de las terapias antiamiloide
|
|
EP1788415A4
(en)
|
2004-07-13 |
2008-11-26 |
Fujikura Ltd |
HOLES-ASSISTED TYPE FIBER AND MULTIMODE FIXED TROUGH FIBER WITH LOW TORSION LOSS
|
|
AT413946B
(de)
|
2004-07-13 |
2006-07-15 |
Mattner Frank Dr |
Impfstoff gegen die alzheimer-krankheit
|
|
KR101068289B1
(ko)
|
2004-07-30 |
2011-09-28 |
리나트 뉴로사이언스 코퍼레이션 |
아밀로이드-베타 펩티드에 대해 지시된 항체 및 이의 사용 방법
|
|
WO2006031653A2
(en)
*
|
2004-09-10 |
2006-03-23 |
Wyeth |
Humanized anti-5t4 antibodies and anti-5t4 antibody / calicheamicin conjugates
|
|
US20090247931A1
(en)
|
2004-09-23 |
2009-10-01 |
Novo Nordisk A/S |
Device for self-care support
|
|
CN1276024C
(zh)
|
2004-09-30 |
2006-09-20 |
北京科技大学 |
含缺陷管道修复补强的碳纤维复合材料和方法
|
|
WO2006042158A2
(en)
*
|
2004-10-05 |
2006-04-20 |
Wyeth |
Methods and compositions for improving recombinant protein production
|
|
WO2006047670A2
(en)
*
|
2004-10-26 |
2006-05-04 |
Wyeth |
Methods for assessing antibodies to neurodegenerative disease-associated antigens
|
|
PT3540062T
(pt)
|
2004-11-16 |
2021-07-06 |
Humanigen Inc |
Permuta de cassete de região variável de imunoglobulina
|
|
WO2006066118A2
(en)
|
2004-12-15 |
2006-06-22 |
Neuralab Limited |
Contextual fear test for predicting efficacy of alzheimer immunotherapeutic treatment
|
|
TW200635608A
(en)
|
2004-12-15 |
2006-10-16 |
Neuralab Ltd |
Aβ antibodies for use in improving cognition
|
|
WO2006066233A1
(en)
|
2004-12-15 |
2006-06-22 |
Neuralab Limited |
An immunoprecipitation-based assay for predicting in vivo efficacy of beta-amyloid antibodies
|
|
AR051528A1
(es)
|
2004-12-15 |
2007-01-17 |
Neuralab Ltd |
Anticuerpos humanizados que reconocen el peptido beta amiloideo
|
|
AR052051A1
(es)
|
2004-12-15 |
2007-02-28 |
Neuralab Ltd |
Anticuerpos ab humanizados usados en mejorar la cognicion
|
|
CA2589860A1
(en)
|
2005-01-24 |
2006-08-03 |
Amgen Inc. |
Humanized anti-amyloid antibody
|
|
KR20070107079A
(ko)
*
|
2005-01-28 |
2007-11-06 |
와이어쓰 |
안정화된 액체 폴리펩타이드 제형
|
|
GT200600031A
(es)
*
|
2005-01-28 |
2006-08-29 |
|
Formulacion anticuerpo anti a beta
|
|
US7731962B2
(en)
|
2005-02-14 |
2010-06-08 |
Merck & Co., Inc. |
Anti-ADDL monoclonal antibody and use thereof
|
|
UY29504A1
(es)
|
2005-04-29 |
2006-10-31 |
Rinat Neuroscience Corp |
Anticuerpos dirigidos contra el péptido amiloide beta y métodos que utilizan los mismos.
|
|
EP1879613B1
(en)
|
2005-05-05 |
2011-11-30 |
Merck Sharp & Dohme Corp. |
Peptide conjugate compositions and methods for the prevention and treatment of alzheimer's disease
|
|
WO2006138553A2
(en)
*
|
2005-06-17 |
2006-12-28 |
Wyeth |
Methods of purifying fc region containing proteins
|
|
WO2007011810A1
(en)
|
2005-07-18 |
2007-01-25 |
Merck & Co., Inc. |
Spiropiperidine beta-secretase inhibitors for the treatment of alzheimer's disease
|
|
US8211648B2
(en)
|
2005-07-22 |
2012-07-03 |
Kalobios Pharmaceuticals, Inc. |
Secretion of antibodies without signal peptides from bacteria
|
|
AU2006297173A1
(en)
|
2005-09-29 |
2007-04-12 |
Viral Logic Systems Technology Corp. |
Immunomodulatory compositions and uses therefor
|
|
EP3211946B1
(en)
|
2005-10-04 |
2018-09-19 |
Huawei Technologies Co., Ltd. |
A method and system for determining the group number used by mobile terminals having a same frequency band position for receiving signals in idle mode
|
|
JP2009516654A
(ja)
|
2005-11-10 |
2009-04-23 |
ロスキャンプ リサーチ， エルエルシー |
Ａ−ベータペプチドによる血管新生の調節
|
|
EP1951892A4
(en)
|
2005-11-22 |
2009-01-14 |
Univ Pennsylvania |
ANTIBODY TREATMENT OF MORBUS ALZHEIMER AND RELATED DISEASES
|
|
RS53291B
(en)
|
2005-12-12 |
2014-08-29 |
Ac Immune S.A. |
BETA 1-42 SPECIFIC MONOCLONIC ANTIBODIES WITH THERAPEUTIC PROPERTIES
|
|
KR101263294B1
(ko)
*
|
2006-03-30 |
2013-06-04 |
글락소 그룹 리미티드 |
아밀로이드베타 펩티드에 대한 항체
|
|
WO2010044803A1
(en)
|
2008-10-17 |
2010-04-22 |
Elan Pharma International Limited |
Treatment of amyloidogenic diseases
|
|
US8784810B2
(en)
|
2006-04-18 |
2014-07-22 |
Janssen Alzheimer Immunotherapy |
Treatment of amyloidogenic diseases
|
|
TWI305843B
(en)
*
|
2006-04-24 |
2009-02-01 |
Young Optics Inc |
Dlp projection apparatus
|
|
CL2007002070A1
(es)
|
2006-07-14 |
2008-02-08 |
Ac Immune S A Genentech Inc |
Anticuerpo quimerico o humanizado, o fragmentos de ellos, que se adhieren especificamente a por lo menos un epitopo en la proteina beta-amiloide; molecula de acido nucleico que lo codifica; composicion que lo comprende; su uso para tratar enfermedade
|
|
CA2680762A1
(en)
|
2007-03-12 |
2008-09-25 |
National Institute Of Radiological Sciences |
Pet visualization of amyloid-associated neuroinflammation in the brain
|
|
US8003097B2
(en)
*
|
2007-04-18 |
2011-08-23 |
Janssen Alzheimer Immunotherapy |
Treatment of cerebral amyloid angiopathy
|
|
KR20100016661A
(ko)
*
|
2007-04-18 |
2010-02-12 |
얀센 알츠하이머 이뮤노테라피 |
대뇌 아밀로이드 혈관병증의 예방 및 치료
|
|
PL2182983T3
(pl)
|
2007-07-27 |
2014-10-31 |
Janssen Alzheimer Immunotherap |
Leczenie chorób amyloidowych z wykorzystaniem humanizowanych przeciwciał specyficznych względem Abeta
|
|
JO3076B1
(ar)
|
2007-10-17 |
2017-03-15 |
Janssen Alzheimer Immunotherap |
نظم العلاج المناعي المعتمد على حالة apoe
|
|
US9272030B2
(en)
|
2007-10-17 |
2016-03-01 |
Janssen Sciences Ireland Uc |
Use of tau to monitor immunotherapy
|
|
DK2237803T3
(en)
|
2007-12-28 |
2015-10-05 |
Prothena Biosciences Ltd |
Treatment and prophylaxis of amyloidosis
|
|
DK2323696T3
(en)
|
2008-09-18 |
2018-11-26 |
Cedars Sinai Medical Center |
OPTICAL PROCEDURE FOR DETECTING ALZHEIMER'S DISEASE
|
|
US20130084245A1
(en)
|
2010-02-25 |
2013-04-04 |
Wyeth Llc |
Pet monitoring of a-beta-directed immunotherapy
|
|
US8689528B1
(en)
|
2011-11-08 |
2014-04-08 |
Seda Gaspari |
Method of packaging a plurality of tissues for dispensing
|