ATE546531T1 - Transaktivierungssystem für säugerzellen - Google Patents
Transaktivierungssystem für säugerzellenInfo
- Publication number
- ATE546531T1 ATE546531T1 AT04815827T AT04815827T ATE546531T1 AT E546531 T1 ATE546531 T1 AT E546531T1 AT 04815827 T AT04815827 T AT 04815827T AT 04815827 T AT04815827 T AT 04815827T AT E546531 T1 ATE546531 T1 AT E546531T1
- Authority
- AT
- Austria
- Prior art keywords
- mammal cells
- methods
- host cell
- desired polypeptide
- transactivation system
- Prior art date
Links
- 241000124008 Mammalia Species 0.000 title 1
- 230000023603 positive regulation of transcription initiation, DNA-dependent Effects 0.000 title 1
- 229920001184 polypeptide Polymers 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 102000007056 Recombinant Fusion Proteins Human genes 0.000 abstract 1
- 108010008281 Recombinant Fusion Proteins Proteins 0.000 abstract 1
- 108091023040 Transcription factor Proteins 0.000 abstract 1
- 102000040945 Transcription factor Human genes 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 108091006106 transcriptional activators Proteins 0.000 abstract 1
- 239000013598 vector Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
Landscapes
- Genetics & Genomics (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US53391703P | 2003-12-31 | 2003-12-31 | |
| PCT/US2004/043830 WO2005065348A2 (en) | 2003-12-31 | 2004-12-30 | Transactivation system for mammalian cells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE546531T1 true ATE546531T1 (de) | 2012-03-15 |
Family
ID=34748979
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04815827T ATE546531T1 (de) | 2003-12-31 | 2004-12-30 | Transaktivierungssystem für säugerzellen |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US8354251B2 (de) |
| EP (1) | EP1702071B1 (de) |
| AT (1) | ATE546531T1 (de) |
| WO (1) | WO2005065348A2 (de) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7537930B2 (en) | 2004-07-23 | 2009-05-26 | Immunomedics, Inc. | Mammalian cell lines for increasing longevity and protein yield from a cell culture |
| KR100984602B1 (ko) * | 2004-11-18 | 2010-09-30 | 고쿠리츠다이가쿠호진 히로시마다이가쿠 | 유전자 증폭에 의해 형성된 반복서열로부터, 발현이 억제된단백질을 발현시키는 방법, 키트, 및 형질전환체 |
| ES2864039T3 (es) | 2005-05-20 | 2021-10-13 | Lonza Biologics Plc | Expresión de alto nivel de un anticuerpo recombinante en una célula huésped de mamífero |
| EP2035448A4 (de) | 2006-06-01 | 2010-11-03 | Elan Pharm Inc | Neuroaktive fragmente von app |
| EP2118270A2 (de) * | 2007-01-08 | 2009-11-18 | Millipore Corporation | Zellkulturverfahren für die produktion rekombinanter proteine bei verminderter konzentration von einem oder mehreren kontaminanten |
| JO3076B1 (ar) | 2007-10-17 | 2017-03-15 | Janssen Alzheimer Immunotherap | نظم العلاج المناعي المعتمد على حالة apoe |
| MY186219A (en) | 2009-08-11 | 2021-06-30 | Genentech Inc | Production of proteins in glutamine-free cell culture media |
| AU2011217848B8 (en) | 2010-02-18 | 2015-09-24 | The Regents Of The University Of California | Integrin aVB8 neutralizing antibody |
| AU2014236207B2 (en) | 2013-03-14 | 2019-05-23 | Salk Institute For Biological Studies | Oncolytic adenovirus compositions |
| CA2961748A1 (en) * | 2014-09-24 | 2016-03-31 | Salk Institute For Biological Studies | Oncolytic tumor viruses and methods of use |
| CN117384961A (zh) | 2016-02-23 | 2024-01-12 | 萨克生物研究学院 | 对病毒动力学影响最小的治疗性腺病毒中的外源基因表达 |
| CA3013637A1 (en) | 2016-02-23 | 2017-08-31 | Salk Institute For Biological Studies | High throughput assay for measuring adenovirus replication kinetics |
| WO2018111767A1 (en) | 2016-12-12 | 2018-06-21 | Salk Institute For Biological Studies | Tumor-targeting synthetic adenoviruses and uses thereof |
| US20220193266A1 (en) * | 2019-04-30 | 2022-06-23 | Chan Zuckerberg Biohub, Inc. | A novel chromatin-opening element for stable long term gene expression |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8900483D0 (en) | 1989-01-10 | 1989-03-08 | Celltech Ltd | Recombinant dna method |
| US6274341B1 (en) | 1997-10-09 | 2001-08-14 | James E. Bailey | Cytostatic process increases the productivity of cultured cells |
| CN100365127C (zh) * | 1998-07-21 | 2008-01-30 | 密理博公司 | 具有遍在染色质开放表达元件(ucoe)的聚核苷酸 |
| ATE539161T1 (de) | 1998-07-21 | 2012-01-15 | Millipore Corp | Ein ein allgegenwärtiges chromatin-öffnendes element (ucoe) enthaltendes polynucleotid |
| US6780639B1 (en) * | 1999-08-24 | 2004-08-24 | Universite Libre De Bruxelles | Antibiotic inducible/repressible genetic construct for gene therapy or gene immunization |
| AU2001259759A1 (en) * | 2000-05-12 | 2001-11-26 | Erik A. Whitehorn | Methods and compositions for amplifying intracellular signal transduction |
| CA2452005C (en) * | 2001-07-10 | 2011-03-15 | Idec Pharmaceutical Corporation | Inhibition of apoptosis process and improvement of cell performance |
-
2004
- 2004-12-30 WO PCT/US2004/043830 patent/WO2005065348A2/en not_active Application Discontinuation
- 2004-12-30 EP EP04815827A patent/EP1702071B1/de not_active Not-in-force
- 2004-12-30 AT AT04815827T patent/ATE546531T1/de active
- 2004-12-30 US US10/585,149 patent/US8354251B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO2005065348A2 (en) | 2005-07-21 |
| US8354251B2 (en) | 2013-01-15 |
| US20090111144A1 (en) | 2009-04-30 |
| EP1702071A2 (de) | 2006-09-20 |
| EP1702071A4 (de) | 2007-07-25 |
| EP1702071B1 (de) | 2012-02-22 |
| WO2005065348A3 (en) | 2005-10-27 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE546531T1 (de) | Transaktivierungssystem für säugerzellen | |
| ES2140542T3 (es) | Celulas madre embrionarias para la obtencion de ungulados quimericos y transgenicos. | |
| TW200732472A (en) | Method for the recombinant expression of a polypeptide | |
| EA199900483A1 (ru) | δ-ЭНДОТОКСИНЫ ШИРОКОГО СПЕКТРА ДЕЙСТВИЯ | |
| ATE272109T1 (de) | Rekombinante collagenase typ i aus clostridium histolyticum und ihre verwendung zur isolierung von zellen und zellverbänden | |
| AR018023A1 (es) | Procedimiento para la fabricacion de polipeptidos con glicosilacion apropiada | |
| ATE440949T1 (de) | Gesteuertes überlesen von stopcodons | |
| CA2672809A1 (en) | Vector for expressing recombinant protein and cho cells transfected with same | |
| CY1118782T1 (el) | Επιλογη κυτταρων που εκφραζουν ετερομερη πολυπεπτιδια | |
| DK1222298T3 (da) | Vektorer og fremgangsmåder til rekombinant proteinekspression | |
| AR020331A1 (es) | Construccion, y metodo para producir una proteina en una celula de planta | |
| DK1332222T3 (da) | Stofskifteændringer i fermenteringer der udtrykker rekombinante proteiner | |
| DE59807479D1 (de) | Fluoreszierende proteine als zelltypspezifische reporter | |
| ATE448312T1 (de) | Leitsequenzen zur verwendung bei der produktion von proteinen | |
| DK0547064T3 (da) | Proteaseresistent PDGF og anvendelsesfremgangsmåde | |
| AU2008232699A8 (en) | High expression clones of mammalian cells with fluorescent protein A or G | |
| ATE404673T1 (de) | Bakteriocin gegen listeria | |
| DE60026733D1 (de) | Histone-deacetylase-8 proteine, nukleinsäuren und methoden zur verwendung | |
| DE69735604D1 (de) | Hypophysentumor verursachende gene und verwandte produkte | |
| DK1626992T3 (da) | Produktion af rekombinant IgM i PER.C6-celler | |
| DK1009834T3 (da) | Regulering af proteinsekretion | |
| AR020208A1 (es) | Construcciones de adn | |
| ATE302282T1 (de) | Erhöhte herstellung von sekretierten proteinen durch rekombinante hefezellen | |
| ATE409746T1 (de) | Neuer spannungsabhängiger kaliumkanal und seine verwendung zur entwicklung von therapeutika | |
| EA200101093A1 (ru) | Экспрессия гепарин-связывающего протеина в рекомбинантных клетках млекопитающих |