DE60336415D1 - Verfahren zur gewinnung einer rekombinanten säuger- myeloma zelllinie adaptiert an wachstum in serum- und proteinfreien medien - Google Patents

Verfahren zur gewinnung einer rekombinanten säuger- myeloma zelllinie adaptiert an wachstum in serum- und proteinfreien medien

Info

Publication number: DE60336415D1
Authority: DE; Germany
Prior art keywords: madomy; serum; protein; growth; cell line
Prior art date: 2002-10-23
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

DE60336415T

Other languages

English (en)

Inventor

Rodriguez Rolando Perez

Vitlloch Adolfo Castillo

Sarazola Svieta Vitores

Ayo Tammy Boggiano

Del Calvo Luis Rojas

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Centro de Immunologia Molecular

Original Assignee

Centro de Immunologia Molecular

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-10-23

Filing date

2003-10-22

Publication date

2011-04-28

2003-10-22 Application filed by Centro de Immunologia Molecular filed Critical Centro de Immunologia Molecular

2011-04-28 Application granted granted Critical

2011-04-28 Publication of DE60336415D1 publication Critical patent/DE60336415D1/de

2023-10-23 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Links

239000004017 serum-free culture medium Substances 0.000 title 2
206010035226 Plasma cell myeloma Diseases 0.000 title 1
201000000050 myeloid neoplasm Diseases 0.000 title 1
210000002966 serum Anatomy 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2809—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0693—Tumour cells; Cancer cells
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0693—Tumour cells; Cancer cells
- C12N5/0694—Cells of blood, e.g. leukemia cells, myeloma cells
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/90—Serum-free medium, which may still contain naturally-sourced components
- C12N2500/95—Protein-free medium and culture conditions
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
- C12N2510/02—Cells for production

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Genetics & Genomics (AREA)
Immunology (AREA)
Biomedical Technology (AREA)
Zoology (AREA)
General Health & Medical Sciences (AREA)
Biochemistry (AREA)
Wood Science & Technology (AREA)
Biotechnology (AREA)
Bioinformatics & Cheminformatics (AREA)
Molecular Biology (AREA)
Oncology (AREA)
Biophysics (AREA)
Medicinal Chemistry (AREA)
Microbiology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
General Engineering & Computer Science (AREA)
Cell Biology (AREA)
Hematology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Peptides Or Proteins (AREA)

DE60336415T 2002-10-23 2003-10-22 Verfahren zur gewinnung einer rekombinanten säuger- myeloma zelllinie adaptiert an wachstum in serum- und proteinfreien medien Expired - Lifetime DE60336415D1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
CU20020239A CU23097A1 (es)	2002-10-23	2002-10-23	Método para la obtención de líneas celulares en medio libre de proteína y líneas celulares obtenidas por este método
PCT/CU2003/000012 WO2004038010A1 (es)	2002-10-23	2003-10-22	Método para la obtención de líneas celulares en medio libre de proteína y líneas celulares obtenidas por este método

Publications (1)

Publication Number	Publication Date
DE60336415D1 true DE60336415D1 (de)	2011-04-28

Family

ID=40134843

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE60336415T Expired - Lifetime DE60336415D1 (de)	2002-10-23	2003-10-22	Verfahren zur gewinnung einer rekombinanten säuger- myeloma zelllinie adaptiert an wachstum in serum- und proteinfreien medien

Country Status (27)

Country	Link
US (2)	US20060036082A1 (de)
EP (2)	EP1564285B1 (de)
JP (1)	JP4674087B2 (de)
KR (1)	KR101186048B1 (de)
CN (1)	CN1714147B (de)
AR (1)	AR041645A1 (de)
AT (1)	ATE502103T1 (de)
AU (1)	AU2003273727B2 (de)
CA (1)	CA2503315C (de)
CU (1)	CU23097A1 (de)
DE (1)	DE60336415D1 (de)
DK (1)	DK1564285T3 (de)
EA (1)	EA007465B1 (de)
EC (1)	ECSP055740A (de)
ES (2)	ES2624279T3 (de)
GE (1)	GEP20084444B (de)
HK (1)	HK1084414A1 (de)
HR (1)	HRP20050760A2 (de)
LT (1)	LT5354B (de)
LV (1)	LV13361B (de)
MY (1)	MY144088A (de)
NZ (1)	NZ540171A (de)
PE (1)	PE20040552A1 (de)
PT (1)	PT1564285E (de)
TN (1)	TNSN05116A1 (de)
UY (1)	UY28037A1 (de)
WO (1)	WO2004038010A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN104673754B (zh) *	2015-02-14	2018-03-02	百泰生物药业有限公司	重组骨髓瘤细胞克隆的筛选方法及由此获得的抗体分子
CN104651314B (zh) *	2015-02-14	2018-06-19	百泰生物药业有限公司	获得高产稳定表达细胞克隆的方法及由此获得的抗体分子

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* Cited by examiner, † Cited by third party
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US3694263A (en) *	1970-10-23	1972-09-26	Joseph J Korn Sr	Swimming pool cleaning methods and apparatus therefor
CU22545A1 (es) *	1994-11-18	1999-03-31	Centro Inmunologia Molecular	Obtención de un anticuerpo quimérico y humanizado contra el receptor del factor de crecimiento epidérmico para uso diagnóstico y terapéutico
US3886616A (en) *	1972-12-06	1975-06-03	Fay A Hayes	Hand propelled swimming pool cleaner
US4275474A (en) *	1979-04-30	1981-06-30	Woodard Randle C	Vacuum head for swimming pool cleaning system
US4240174A (en) *	1979-07-30	1980-12-23	Scott Jeffrey L	Self-contained mobile pool cleaning apparatus
US4430214A (en) *	1982-09-15	1984-02-07	Baker Marvin E	Strainer mill for swimming pool pump intake
AU2986484A (en) *	1983-06-27	1985-01-03	Monash University	Leptospira strains grown in protein free medium
US4558479A (en) *	1984-01-26	1985-12-17	Alopex Industries, Inc.	Pool cleaner
US4683599A (en) *	1984-03-30	1987-08-04	Fahet Nv	Automatic pool cleaner fitting
US4581075A (en) *	1985-03-15	1986-04-08	Maxi-Sweep, Inc.	Self-propelled water borne pool cleaner
AU6291090A (en)	1989-09-29	1991-04-28	Atomic Energy Of Canada Limited	Infrared-based gas detector
JP2696001B2 (ja)	1991-04-15	1998-01-14	財団法人化学及血清療法研究所	組換え蛋白質産生用培地
EP0531562A1 (de)	1991-09-11	1993-03-17	Doerr, Hans-Wilhelm, Prof. Dr. med.	Kultivierung von Säugetierzellen
EP0784684B8 (de) *	1994-09-16	2008-03-26	Cancer Research Institute of Contra Costa	Rekombinantpeptide hergeleitet vom mc3 antikörper gegen ba46, verfahren zu deren verwendung und verfahren zur humanisierung von antikörperpeptiden
WO1996015231A2 (en)	1994-11-10	1996-05-23	Immuno Aktiengesellschaft	Method for producing biologicals in protein-free culture
DE69608668T2 (de)	1995-02-23	2001-02-01	Quest Int	Peptide für gewebe- und zellkulturmedien
AUPN442295A0 (en)	1995-07-26	1995-08-17	Commonwealth Scientific And Industrial Research Organisation	Regulated autocrine growth of mammalian cells
CU22584A1 (es) *	1995-11-17	1999-11-03	Centro Inmunologia Molecular	Composiciones farmacéuticas que contienen un anticuerpo monoclonal que reconoce el antígeno de diferenciación leucocitario humano cd6 y sus usos para el diagnóstico y tratamiento de la psoriasis
AT407255B (de) *	1997-06-20	2001-02-26	Immuno Ag	Rekombinanter zellklon mit erhöhter stabilität in serum- und proteinfreiem medium und verfahren zur gewinnung des stabilen zellklons

2002
- 2002-10-23 CU CU20020239A patent/CU23097A1/es unknown
2003
- 2003-10-10 PE PE2003001035A patent/PE20040552A1/es not_active Application Discontinuation
- 2003-10-16 AR ARP030103776A patent/AR041645A1/es active IP Right Grant
- 2003-10-17 MY MYPI20033959A patent/MY144088A/en unknown
- 2003-10-22 DE DE60336415T patent/DE60336415D1/de not_active Expired - Lifetime
- 2003-10-22 NZ NZ540171A patent/NZ540171A/en not_active IP Right Cessation
- 2003-10-22 DK DK03757654.3T patent/DK1564285T3/da active
- 2003-10-22 EA EA200500695A patent/EA007465B1/ru not_active IP Right Cessation
- 2003-10-22 WO PCT/CU2003/000012 patent/WO2004038010A1/es active IP Right Grant
- 2003-10-22 US US10/532,269 patent/US20060036082A1/en not_active Abandoned
- 2003-10-22 CN CN2003801036918A patent/CN1714147B/zh not_active Expired - Lifetime
- 2003-10-22 ES ES11155076.0T patent/ES2624279T3/es not_active Expired - Lifetime
- 2003-10-22 EP EP03757654A patent/EP1564285B1/de not_active Expired - Lifetime
- 2003-10-22 GE GEAP20038815A patent/GEP20084444B/en unknown
- 2003-10-22 KR KR1020057006995A patent/KR101186048B1/ko active IP Right Grant
- 2003-10-22 ES ES03757654T patent/ES2360049T3/es not_active Expired - Lifetime
- 2003-10-22 EP EP11155076.0A patent/EP2363418B1/de not_active Expired - Lifetime
- 2003-10-22 JP JP2004545689A patent/JP4674087B2/ja not_active Expired - Lifetime
- 2003-10-22 CA CA2503315A patent/CA2503315C/en not_active Expired - Lifetime
- 2003-10-22 AT AT03757654T patent/ATE502103T1/de active
- 2003-10-22 PT PT03757654T patent/PT1564285E/pt unknown
- 2003-10-22 AU AU2003273727A patent/AU2003273727B2/en not_active Expired
- 2003-10-23 UY UY28037A patent/UY28037A1/es not_active Application Discontinuation
2005
- 2005-04-22 TN TNP2005000116A patent/TNSN05116A1/en unknown
- 2005-04-22 EC EC2005005740A patent/ECSP055740A/es unknown
- 2005-05-19 LT LT2005053A patent/LT5354B/lt not_active IP Right Cessation
- 2005-05-23 LV LVP-05-61A patent/LV13361B/en unknown
- 2005-09-02 HR HR20050760A patent/HRP20050760A2/xx not_active Application Discontinuation
2006
- 2006-04-13 HK HK06104515.2A patent/HK1084414A1/xx not_active IP Right Cessation
2010
- 2010-04-13 US US12/759,208 patent/US20100197011A1/en not_active Abandoned

Also Published As

Publication number	Publication date
EP2363418A2 (de)	2011-09-07
BR0315565B1 (pt)	2022-01-25
AR041645A1 (es)	2005-05-26
EP1564285B1 (de)	2011-03-16
PT1564285E (pt)	2011-04-20
ES2360049T3 (es)	2011-05-31
KR101186048B1 (ko)	2012-09-25
ECSP055740A (es)	2005-09-20
HRP20050760A2 (en)	2006-08-31
HK1084414A1 (en)	2006-07-28
AU2003273727A1 (en)	2004-05-13
LV13361B (en)	2006-02-20
BR0315565A (pt)	2005-08-23
LT5354B (lt)	2006-07-25
CN1714147A (zh)	2005-12-28
AU2003273727B2 (en)	2008-04-03
US20060036082A1 (en)	2006-02-16
CN1714147B (zh)	2011-01-12
EP2363418A3 (de)	2011-11-16
ES2624279T3 (es)	2017-07-13
CU23097A1 (es)	2005-11-18
EA007465B1 (ru)	2006-10-27
JP4674087B2 (ja)	2011-04-20
DK1564285T3 (da)	2011-05-16
EP2363418B1 (de)	2017-02-08
EP1564285A1 (de)	2005-08-17
UY28037A1 (es)	2004-04-30
ATE502103T1 (de)	2011-04-15
CA2503315C (en)	2014-02-18
TNSN05116A1 (en)	2007-05-14
KR20050088403A (ko)	2005-09-06
PE20040552A1 (es)	2004-10-26
WO2004038010A1 (es)	2004-05-06
NZ540171A (en)	2008-04-30
MY144088A (en)	2011-08-15
US20100197011A1 (en)	2010-08-05
GEP20084444B (en)	2008-08-10
CA2503315A1 (en)	2004-05-06
JP2006503879A (ja)	2006-02-02
EA200500695A1 (ru)	2005-10-27
LT2005053A (en)	2006-04-25

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