CZ20012965A3 - Deriváty benzaldehydu vhodné jako protinádorové prostředky - Google Patents

Deriváty benzaldehydu vhodné jako protinádorové prostředky Download PDF

Info

Publication number
CZ20012965A3
CZ20012965A3 CZ20012965A CZ20012965A CZ20012965A3 CZ 20012965 A3 CZ20012965 A3 CZ 20012965A3 CZ 20012965 A CZ20012965 A CZ 20012965A CZ 20012965 A CZ20012965 A CZ 20012965A CZ 20012965 A3 CZ20012965 A3 CZ 20012965A3
Authority
CZ
Czechia
Prior art keywords
compound
cells
tumor
cell
liver
Prior art date
Application number
CZ20012965A
Other languages
Czech (cs)
English (en)
Inventor
Bernt Borretzen
Vidar Moen
Rolf Olaf Larsen
Erik Olai Pettersen
Camilla Bruno Dunsaed
Geir Sagvolden
Original Assignee
Norsk Hydro Asa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Norsk Hydro Asa filed Critical Norsk Hydro Asa
Publication of CZ20012965A3 publication Critical patent/CZ20012965A3/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H9/00—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
    • C07H9/02—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical the hetero ring containing only oxygen as ring hetero atoms
    • C07H9/04—Cyclic acetals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/18—Acyclic radicals, substituted by carbocyclic rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CZ20012965A 1999-02-19 2000-02-18 Deriváty benzaldehydu vhodné jako protinádorové prostředky CZ20012965A3 (cs)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NO990814A NO309305B1 (no) 1999-02-19 1999-02-19 Anvendelse av benzaldehydderivater ved fremstilling av farmasöytiske preparater for forebygging og/eller behandling av kreft, samt visse nye benzaldehydderivater

Publications (1)

Publication Number Publication Date
CZ20012965A3 true CZ20012965A3 (cs) 2002-03-13

Family

ID=19902986

Family Applications (2)

Application Number Title Priority Date Filing Date
CZ20012966A CZ20012966A3 (cs) 1999-02-19 2000-02-18 Deriváty benzaldehydu vhodné jako protinádorové prostředky
CZ20012965A CZ20012965A3 (cs) 1999-02-19 2000-02-18 Deriváty benzaldehydu vhodné jako protinádorové prostředky

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CZ20012966A CZ20012966A3 (cs) 1999-02-19 2000-02-18 Deriváty benzaldehydu vhodné jako protinádorové prostředky

Country Status (15)

Country Link
EP (2) EP1150690A1 (es)
JP (2) JP2002537263A (es)
CN (2) CN1347323A (es)
AU (2) AU2834200A (es)
BR (2) BR0008302A (es)
CA (2) CA2363670A1 (es)
CZ (2) CZ20012966A3 (es)
HU (2) HUP0105281A2 (es)
IL (2) IL144896A0 (es)
MX (2) MXPA01008347A (es)
NO (1) NO309305B1 (es)
PL (2) PL350519A1 (es)
RU (2) RU2001123124A (es)
SK (2) SK11612001A3 (es)
WO (2) WO2000048609A1 (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002096921A1 (fr) * 2001-05-30 2002-12-05 Nisshin Seifun Group Inc. Nouveau derive glucose induisant l'apoptose, procede de production et utilisation comme medicament
DE10261807A1 (de) * 2002-12-19 2004-07-01 Turicum Drug Development Ag Deuterierte Catecholaminderivate sowie diese Verbindungen enthaltende Arzneimittel
TWI394750B (zh) * 2005-07-26 2013-05-01 Takeda Gmbh 同位素取代之質子泵抑制劑
AR054583A1 (es) * 2005-07-26 2007-06-27 Altana Pharma Ag Pantoprazol isotopicamente sustituido
CA2624179A1 (en) * 2005-10-06 2007-04-12 Auspex Pharmaceuticals, Inc. Deuterated inhibitors of gastric h+, k+-atpase with enhanced therapeutic properties
CN101157711B (zh) * 2007-09-28 2010-12-08 西安交通大学 一种具有抗肿瘤活性的化合物及其用途
CN102046180A (zh) * 2008-04-03 2011-05-04 同源3公司 用于免疫治疗的组合物和方法
CN101735284B (zh) * 2008-11-24 2012-05-23 上海医药工业研究院 一种4,6-o-苄叉-d-吡喃葡萄糖的制备方法
IL305990A (en) 2013-12-03 2023-11-01 Intra Cellular Therapies Inc Compressed gamma-carboline heterocyclic compounds are modified for use in the treatment of type I and/or type II bipolar disorders
ES2961843T3 (es) * 2014-04-04 2024-03-14 Intra Cellular Therapies Inc Gamma-carbolinas condensadas con heterociclo deuteradas como antagonistas de los receptores de 5-HT2A
JP6898072B2 (ja) * 2015-08-27 2021-07-07 秀行 佐谷 １４−３−３タンパク質活性調節剤
AU2017238842B2 (en) 2016-03-25 2019-06-20 Intra-Cellular Therapies, Inc. Organic compounds
WO2018071233A1 (en) 2016-10-12 2018-04-19 Intra-Cellular Therapies, Inc. Amorphous solid dispersions
IL268970B2 (en) 2017-03-24 2023-12-01 Intra Cellular Therapies Inc Oral preparations of heterocyclic gamma carboline derivatives fused for absorption through mucous membranes
KR20210052472A (ko) 2018-08-31 2021-05-10 인트라-셀룰라 써래피스, 인코퍼레이티드. 신규한 방법
CN112584837A (zh) 2018-08-31 2021-03-30 细胞内治疗公司 新方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB811510A (en) * 1954-12-20 1959-04-08 Gyogyszeripari Ki New nitrogen-containing derivatives of polyhydroxy compounds and process for the preparation thereof
JPS6112623A (ja) * 1984-06-28 1986-01-21 Kaken Pharmaceut Co Ltd エンケフアリナ−ゼ阻害剤
JPS6256423A (ja) * 1985-09-06 1987-03-12 Kaken Pharmaceut Co Ltd 悪液質治療改善剤
GB8705780D0 (en) * 1987-03-11 1987-04-15 Norsk Hydro As Anticancer compounds
JPH07145191A (ja) * 1993-11-24 1995-06-06 Japan Tobacco Inc ガラクトシルホスフォネート誘導体

Also Published As

Publication number Publication date
NO990814L (no) 2000-08-21
MXPA01008347A (es) 2004-03-10
BR0008302A (pt) 2002-08-27
NO309305B1 (no) 2001-01-15
EP1150689A1 (en) 2001-11-07
RU2001123124A (ru) 2004-02-20
SK11602001A3 (sk) 2002-02-05
AU2834200A (en) 2000-09-04
CA2362306A1 (en) 2000-08-24
CN1347323A (zh) 2002-05-01
HUP0105281A2 (hu) 2002-05-29
JP2002537263A (ja) 2002-11-05
NO990814D0 (no) 1999-02-19
HUP0105280A2 (hu) 2002-04-29
EP1150690A1 (en) 2001-11-07
BR0008297A (pt) 2002-05-28
JP2002537264A (ja) 2002-11-05
CA2363670A1 (en) 2000-08-24
IL144895A0 (en) 2002-06-30
AU2834100A (en) 2000-09-04
WO2000048610A1 (en) 2000-08-24
CN1347322A (zh) 2002-05-01
PL350519A1 (en) 2002-12-16
RU2001123035A (ru) 2004-03-20
SK11612001A3 (sk) 2002-04-04
IL144896A0 (en) 2002-06-30
WO2000048609A1 (en) 2000-08-24
PL350520A1 (en) 2002-12-16
CZ20012966A3 (cs) 2002-03-13
MXPA01008346A (es) 2003-06-06

Similar Documents

Publication Publication Date Title
CZ20012965A3 (cs) Deriváty benzaldehydu vhodné jako protinádorové prostředky
JP5726171B2 (ja) Ｅ−セレクチンおよびｃｘｃｒ４ケモカイン受容体のヘテロ二官能性阻害剤
JP4187072B2 (ja) アミロイド症の治療法
JP2002510639A (ja) 新生物疾患又は感染性疾患の処置のための新規の配合製剤
CN111973570B (zh) 唾液酸衍生物修饰的依鲁替尼纳米复合物及其制备方法
JPH03500166A (ja) チトカラシンの精製方法および組成物
KR20180117681A (ko) 글리코알칼로이드 조합 및 그의 다양한 용도
EP2825198B1 (en) Glut-1 targeted and curcumin loaded micelles
FR3022458A1 (fr) Utilisation du mannosylglycerate et ses derives comme agent immunostimulant
CN111655254A (zh) 包含新型白杨素衍生物化合物作为活性成分的用于预防或治疗糖尿病并发症的药物组合物
CN108743956B (zh) 一种白蛋白结合型蒽环类抗肿瘤抗生素制剂及其制备方法
AU739033B2 (en) 13-deoxyanthracycline derivatives and processes for preparing them
US20180055949A1 (en) Cancer therapeutics
KR100673565B1 (ko) 인터페론-감마의 항암작용 개선제 및 상기 항암작용 개선제와 인터페론-감마를 유효성분으로 함유하는 항암제용 조성물
KR20010113695A (ko) 화합물
WO1998055493A1 (fr) Substances naturelles antitumorales ou antivirales et leur utilisation
RU2804771C1 (ru) Комплексное антиангиогенное и гипоксия-ориентированное противоопухолевое средство
CN116421590B (zh) 二乙酸氯己定在制备预防或/和治疗肝癌的药物中的用途
TW200405814A (en) Method of treating multiple sclerosis
WO2020158863A1 (ja) アントラサイクリン系化合物を含むミセル剤と免疫賦活剤との組み合わせ医薬
NO312226B1 (no) Anvendelse av 4,6-<Omikron>-(benzyliden-d1)-D-glukopyranose og den tilsvarende 1-isomer ved profylakse og behandling av kreft
JP3660230B2 (ja) 天然型抗腫瘍性又は抗ウイルス性物質およびその用途
NO309815B1 (no) Derivater av 5-nitrofurfural
KR20030091386A (ko) 항종양활성 증진용 조성물