BR9810369A - Processo de transferência de ácido nucleico para o interior de um ou mais músculos estriados, in vivo, composição, ácido mucleico e campo elétrico, e, produto de combinação - Google Patents
Processo de transferência de ácido nucleico para o interior de um ou mais músculos estriados, in vivo, composição, ácido mucleico e campo elétrico, e, produto de combinaçãoInfo
- Publication number
- BR9810369A BR9810369A BR9810369-5A BR9810369A BR9810369A BR 9810369 A BR9810369 A BR 9810369A BR 9810369 A BR9810369 A BR 9810369A BR 9810369 A BR9810369 A BR 9810369A
- Authority
- BR
- Brazil
- Prior art keywords
- nucleic acid
- vivo
- composition
- electric field
- acid
- Prior art date
Links
- 108020004707 nucleic acids Proteins 0.000 title abstract 6
- 150000007523 nucleic acids Chemical class 0.000 title abstract 6
- 102000039446 nucleic acids Human genes 0.000 title abstract 6
- 238000000034 method Methods 0.000 title abstract 3
- 210000003699 striated muscle Anatomy 0.000 title abstract 3
- 239000013066 combination product Substances 0.000 title abstract 2
- 229940127555 combination product Drugs 0.000 title abstract 2
- 230000005684 electric field Effects 0.000 title abstract 2
- 238000001727 in vivo Methods 0.000 title abstract 2
- 239000002253 acid Substances 0.000 title 1
- 238000001415 gene therapy Methods 0.000 abstract 1
- 239000000047 product Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0408—Use-related aspects
- A61N1/0412—Specially adapted for transcutaneous electroporation, e.g. including drug reservoirs
- A61N1/0416—Anode and cathode
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/325—Applying electric currents by contact electrodes alternating or intermittent currents for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Radiology & Medical Imaging (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
- Pyrrole Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
"PROCESSO DE TRANSFERêNCIA DE áCIDO NUCLEICO PARA O INTERIOR DE UM OU MAIS MúSCULOS ESTRIADOS, IN VIVO, COMPOSIçãO, áCIDO NUCLEICO E CAMPO ELéTRICO, E, PRODUTO DE COMBINAçãO". A presente invenção refere-se a um aperfeiçoamento da transferência in vivo, para o interior das células dos músculos estriados, de ácidos nucleicos ou de ácidos nucleicos associados a produtos que permitem aumentar o rendimento dessas transferências, e à combinação de um ácido nucleico e do processo de transferência de acordo com a invenção para sua utilização na terapia gênica.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9708233A FR2765242B1 (fr) | 1997-06-30 | 1997-06-30 | Amelioration du transfert d'acide nucleique dans le muscle strie et combinaison permettant la mise en oeuvre du procede |
US6748897P | 1997-12-01 | 1997-12-01 | |
PCT/FR1998/001400 WO1999001158A1 (fr) | 1997-06-30 | 1998-06-30 | Amelioration du transfert d'acide nucleique dans le muscle strie et combinaison permettant la mise en oeuvre du procede |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9810369A true BR9810369A (pt) | 2000-09-05 |
Family
ID=26233648
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9810369-5A BR9810369A (pt) | 1997-06-30 | 1998-06-30 | Processo de transferência de ácido nucleico para o interior de um ou mais músculos estriados, in vivo, composição, ácido mucleico e campo elétrico, e, produto de combinação |
Country Status (16)
Country | Link |
---|---|
US (1) | US6939862B2 (pt) |
EP (1) | EP0991426B2 (pt) |
JP (1) | JP2002507985A (pt) |
KR (1) | KR20010020571A (pt) |
CN (1) | CN1261807A (pt) |
AT (1) | ATE275423T1 (pt) |
AU (1) | AU8444798A (pt) |
BR (1) | BR9810369A (pt) |
CA (1) | CA2294793A1 (pt) |
CZ (1) | CZ299473B6 (pt) |
DE (1) | DE69826124T3 (pt) |
HU (1) | HUP0004589A3 (pt) |
IL (1) | IL133710A0 (pt) |
NO (1) | NO328102B1 (pt) |
PL (1) | PL337583A1 (pt) |
WO (1) | WO1999001158A1 (pt) |
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1998
- 1998-06-30 JP JP50653099A patent/JP2002507985A/ja active Pending
- 1998-06-30 WO PCT/FR1998/001400 patent/WO1999001158A1/fr active IP Right Grant
- 1998-06-30 CZ CZ0475599A patent/CZ299473B6/cs not_active IP Right Cessation
- 1998-06-30 DE DE69826124T patent/DE69826124T3/de not_active Expired - Lifetime
- 1998-06-30 CN CN98806671A patent/CN1261807A/zh active Pending
- 1998-06-30 IL IL13371098A patent/IL133710A0/xx unknown
- 1998-06-30 AU AU84447/98A patent/AU8444798A/en not_active Abandoned
- 1998-06-30 CA CA002294793A patent/CA2294793A1/fr not_active Abandoned
- 1998-06-30 KR KR1019997012481A patent/KR20010020571A/ko not_active Application Discontinuation
- 1998-06-30 BR BR9810369-5A patent/BR9810369A/pt not_active IP Right Cessation
- 1998-06-30 AT AT98935067T patent/ATE275423T1/de not_active IP Right Cessation
- 1998-06-30 EP EP98935067A patent/EP0991426B2/fr not_active Expired - Lifetime
- 1998-06-30 HU HU0004589A patent/HUP0004589A3/hu unknown
- 1998-06-30 PL PL98337583A patent/PL337583A1/xx not_active Application Discontinuation
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1999
- 1999-12-29 NO NO19996542A patent/NO328102B1/no not_active IP Right Cessation
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2001
- 2001-11-07 US US09/986,033 patent/US6939862B2/en not_active Expired - Lifetime
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AU8444798A (en) | 1999-01-25 |
EP0991426B1 (fr) | 2004-09-08 |
PL337583A1 (en) | 2000-08-28 |
DE69826124D1 (de) | 2004-10-14 |
IL133710A0 (en) | 2001-04-30 |
JP2002507985A (ja) | 2002-03-12 |
US6939862B2 (en) | 2005-09-06 |
HUP0004589A3 (en) | 2003-08-28 |
EP0991426B2 (fr) | 2007-03-28 |
CN1261807A (zh) | 2000-08-02 |
KR20010020571A (ko) | 2001-03-15 |
DE69826124T2 (de) | 2005-09-15 |
ATE275423T1 (de) | 2004-09-15 |
CA2294793A1 (fr) | 1999-01-14 |
NO996542D0 (no) | 1999-12-29 |
WO1999001158A1 (fr) | 1999-01-14 |
NO328102B1 (no) | 2009-12-07 |
NO996542L (no) | 2000-02-17 |
HUP0004589A1 (hu) | 2001-04-28 |
CZ475599A3 (cs) | 2000-07-12 |
DE69826124T3 (de) | 2007-10-11 |
CZ299473B6 (cs) | 2008-08-06 |
US20030073653A1 (en) | 2003-04-17 |
EP0991426A1 (fr) | 2000-04-12 |
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