FR2723371B1 - Oligonucleotide reconnaissant une sequence d'acide nucleique a structure non lineaire, application a des fins therapeutiques et procede de preparation - Google Patents
Oligonucleotide reconnaissant une sequence d'acide nucleique a structure non lineaire, application a des fins therapeutiques et procede de preparationInfo
- Publication number
- FR2723371B1 FR2723371B1 FR9409578A FR9409578A FR2723371B1 FR 2723371 B1 FR2723371 B1 FR 2723371B1 FR 9409578 A FR9409578 A FR 9409578A FR 9409578 A FR9409578 A FR 9409578A FR 2723371 B1 FR2723371 B1 FR 2723371B1
- Authority
- FR
- France
- Prior art keywords
- preparation
- nucleic acid
- acid sequence
- application
- therapeutic purposes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1131—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against viruses
- C12N15/1132—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against viruses against retroviridae, e.g. HIV
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6811—Selection methods for production or design of target specific oligonucleotides or binding molecules
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/11—Antisense
- C12N2310/111—Antisense spanning the whole gene, or a large part of it
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/15—Nucleic acids forming more than 2 strands, e.g. TFOs
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/50—Physical structure
- C12N2310/53—Physical structure partially self-complementary or closed
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Plant Pathology (AREA)
- Virology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- AIDS & HIV (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9409578A FR2723371B1 (fr) | 1994-08-02 | 1994-08-02 | Oligonucleotide reconnaissant une sequence d'acide nucleique a structure non lineaire, application a des fins therapeutiques et procede de preparation |
PCT/FR1995/001036 WO1996004374A1 (fr) | 1994-08-02 | 1995-08-01 | Oligonucleotide reconnaissant une sequence d'acide nucleique a structure non lineaire, application a des fins therapeutiques et procede de preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9409578A FR2723371B1 (fr) | 1994-08-02 | 1994-08-02 | Oligonucleotide reconnaissant une sequence d'acide nucleique a structure non lineaire, application a des fins therapeutiques et procede de preparation |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2723371A1 FR2723371A1 (fr) | 1996-02-09 |
FR2723371B1 true FR2723371B1 (fr) | 1996-10-31 |
Family
ID=9465993
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR9409578A Expired - Fee Related FR2723371B1 (fr) | 1994-08-02 | 1994-08-02 | Oligonucleotide reconnaissant une sequence d'acide nucleique a structure non lineaire, application a des fins therapeutiques et procede de preparation |
Country Status (2)
Country | Link |
---|---|
FR (1) | FR2723371B1 (fr) |
WO (1) | WO1996004374A1 (fr) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6194149B1 (en) | 1998-03-03 | 2001-02-27 | Third Wave Technologies, Inc. | Target-dependent reactions using structure-bridging oligonucleotides |
WO1998050403A1 (fr) | 1997-05-05 | 1998-11-12 | Third Wave Technologies,Inc. | Reactions dependantes des cibles, utilisant des oligonucleotides de pontage de structures |
US7101672B2 (en) | 1998-05-05 | 2006-09-05 | Third Wave Technologies, Inc. | Target-dependent reactions using structure-bridging oligonucleotides |
US6214545B1 (en) | 1997-05-05 | 2001-04-10 | Third Wave Technologies, Inc | Polymorphism analysis by nucleic acid structure probing |
US6210880B1 (en) | 1997-09-19 | 2001-04-03 | Third Wave Technologies, Inc. | Polymorphism analysis by nucleic acid structure probing with structure-bridging oligonucleotides |
US20040092465A1 (en) * | 2002-11-11 | 2004-05-13 | Isis Pharmaceuticals Inc. | Modulation of huntingtin interacting protein 1 expression |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1991017246A1 (fr) * | 1990-05-04 | 1991-11-14 | Isis Pharmaceuticals, Inc. | Procedes de modulation de l'expression des genes par l'interference dans la structure secondaire de l'arn |
WO1992001806A1 (fr) * | 1990-07-16 | 1992-02-06 | The Public Health Research Institute Of The City Of New York, Inc. | Selection de ribozymes assurant un clivage efficace d'arn cible |
-
1994
- 1994-08-02 FR FR9409578A patent/FR2723371B1/fr not_active Expired - Fee Related
-
1995
- 1995-08-01 WO PCT/FR1995/001036 patent/WO1996004374A1/fr active Application Filing
Also Published As
Publication number | Publication date |
---|---|
FR2723371A1 (fr) | 1996-02-09 |
WO1996004374A1 (fr) | 1996-02-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |