BR0205509A - Composição compreendendo partìculas finas de liberação prolongada para comprimidos de rápida desintegração na cavidade bucal e método de fabricação da mesma - Google Patents

Composição compreendendo partìculas finas de liberação prolongada para comprimidos de rápida desintegração na cavidade bucal e método de fabricação da mesma

Info

Publication number
BR0205509A
BR0205509A BR0205509-0A BR0205509A BR0205509A BR 0205509 A BR0205509 A BR 0205509A BR 0205509 A BR0205509 A BR 0205509A BR 0205509 A BR0205509 A BR 0205509A
Authority
BR
Brazil
Prior art keywords
fine particles
composition
rapidly disintegrating
oral cavity
release fine
Prior art date
Application number
BR0205509-0A
Other languages
English (en)
Inventor
Tatsuki Shinoda
Atsushi Maeda
Naoki Itou
Takao Mizumoto
Shigeru Yamazaki
Yuuki Takaishi
Original Assignee
Yamanouchi Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yamanouchi Pharma Co Ltd filed Critical Yamanouchi Pharma Co Ltd
Publication of BR0205509A publication Critical patent/BR0205509A/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/18Sulfonamides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/08Drugs for disorders of the urinary system of the prostate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5026Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)

Abstract

"COMPOSIçãO COMPREENDENDO PARTìCULAS FINAS DE LIBERAçãO PROLONGADA PARA COMPRIMIDOS DE RáPIDA DESINTEGRAçãO NA CAVIDADE BUCAL E MéTODO DE FABRICAçãO DA MESMA". A presente invenção refere-se a uma composição compreendendo partículas finas de liberação prolongada, caracterizada por conter partículas finas de liberação prolongada podendo ser usadas nos comprimidos de rápida desintegração na cavidade bucal, uma ou mais cargas selecionadas do grupo que consiste de açúcares ou álcoois de açúcar e um ou mais aglutinantes para comprimidos de rápida desintegração na cavidade bucal selecionados do grupo que consiste de açúcares de alta moldabilidade e substâncias poliméricas hidrossolúveis, e em que as partículas finas de liberação prolongada são granuladas com carga e aglutinante para comprimidos de rápida desintegração na cavidade bucal, e um método de fabricação da composição.
BR0205509-0A 2001-07-27 2002-07-25 Composição compreendendo partìculas finas de liberação prolongada para comprimidos de rápida desintegração na cavidade bucal e método de fabricação da mesma BR0205509A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US30830301P 2001-07-27 2001-07-27
PCT/JP2002/007550 WO2003009831A1 (en) 2001-07-27 2002-07-25 Compositions containing sustained-release fine grains for tablets quickly disintegrable in the oral cavity and process for producing the same

Publications (1)

Publication Number Publication Date
BR0205509A true BR0205509A (pt) 2003-06-24

Family

ID=23193419

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0205509-0A BR0205509A (pt) 2001-07-27 2002-07-25 Composição compreendendo partìculas finas de liberação prolongada para comprimidos de rápida desintegração na cavidade bucal e método de fabricação da mesma

Country Status (18)

Country Link
US (2) US7255876B2 (pt)
EP (1) EP1413294B1 (pt)
JP (3) JP4019374B2 (pt)
KR (1) KR100530546B1 (pt)
CN (1) CN1473035B (pt)
AT (1) ATE482692T1 (pt)
AU (1) AU2002355222B2 (pt)
BR (1) BR0205509A (pt)
CA (1) CA2419089A1 (pt)
CZ (1) CZ14921U1 (pt)
DE (2) DE60237826D1 (pt)
ES (1) ES2351249T3 (pt)
HU (1) HUP0302351A3 (pt)
MX (1) MXPA03000985A (pt)
PL (1) PL361452A1 (pt)
RU (1) RU2245136C2 (pt)
WO (1) WO2003009831A1 (pt)
ZA (1) ZA200300647B (pt)

Families Citing this family (91)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7815937B2 (en) * 1998-10-27 2010-10-19 Biovail Laboratories International Srl Quick dissolve compositions and tablets based thereon
AU1323400A (en) * 1998-10-27 2000-05-15 Fuisz Technologies Ltd. Microparticles containing peg and/or peg glyceryl esters
JP4019374B2 (ja) * 2001-07-27 2007-12-12 アステラス製薬株式会社 口腔内速崩壊錠用徐放性微粒子含有組成物およびその製造法
NZ532589A (en) * 2001-11-07 2005-02-25 Synthon Bv Tamsulosin tablets
JP4173670B2 (ja) * 2002-03-08 2008-10-29 旭化成ファーマ株式会社 口腔内崩壊製剤
DE10232113A1 (de) 2002-07-16 2004-01-29 Bayer Ag Vardenafil Hydrochlorid Trihydrat enthaltende Arzneimittel
DE10244504A1 (de) * 2002-09-25 2004-04-08 Capsulution Nanoscience Ag Schnellfreisetzende Darreichungsform mit schwerlöslichem Wirkstoff
JP4523265B2 (ja) * 2002-11-13 2010-08-11 旭化成ファーマ株式会社 排尿障害治療用口腔内崩壊製剤
CA2515585A1 (en) * 2003-01-27 2004-08-12 Yoji Tanijiri Enteric sustained-release fine particles for tamsulosin or its salt and manufacturing method thereof
ZA200409537B (en) 2003-01-31 2006-10-25 Yamanouchi Pharma Co Ltd Stable solid medicinal composition for oral administration
DE60300414T2 (de) * 2003-04-30 2006-05-11 Ferring B.V. Feste Dosierungsform mit Desmopressin
DE60308828T2 (de) * 2003-05-20 2007-05-24 Ethypharm Orale pharmazeutische Zusammensetzung mit verzögerter Freisetzung
US7314638B2 (en) * 2003-08-12 2008-01-01 Kyungdong Pharm. Co., Ltd. Preparing method for controlled released type tablet tamsulosin HCL and the tablet thereof
US20070122480A1 (en) * 2003-09-29 2007-05-31 Cj Corporation Sustained release formulations
CN100438914C (zh) * 2003-10-15 2008-12-03 富士化学工业株式会社 用于口腔内快速崩解的片剂的组合物
KR101159617B1 (ko) 2003-10-15 2012-06-27 후지카가쿠고교가부시키가이샤 구강내 속붕해성 정제
DE10350322A1 (de) * 2003-10-23 2005-06-09 Coty B.V. Klimabeständiger kosmetischer Komplex
JPWO2005039542A1 (ja) * 2003-10-27 2007-02-15 アステラス製薬株式会社 口腔内崩壊錠用の薬物含有被覆微粒子
US8197846B2 (en) 2003-11-10 2012-06-12 Astellas Pharma Inc. Sustained release pharmaceutical composition
US8128958B2 (en) 2003-11-10 2012-03-06 Astellas Pharma Inc. Sustained release pharmaceutical composition
WO2005053659A1 (en) * 2003-12-03 2005-06-16 Natco Pharma Limited An improved pharmaceutical formulation containing tamsulosin salt and a process for its preparation
SI21637A (sl) * 2003-12-23 2005-06-30 LEK farmacevtska dru�ba d.d. Farmacevtska oblika z nadzorovanim sproščanjem
KR100582350B1 (ko) * 2004-02-17 2006-05-22 한미약품 주식회사 탐수로신 염산염의 경구투여용 조성물 및 이의 서방성과립 제제
CN1988884B (zh) * 2004-06-10 2013-01-02 格拉特气体技术公司 控制释放基质的药物剂型组成
DE102004028940A1 (de) * 2004-06-15 2006-01-12 Krka Tovarna Zdravil, D.D. Oral zerfallende pharmazeutische Zusammensetzung, die Risperidon enthält
ES2287613T3 (es) * 2004-07-14 2007-12-16 Siegfried Generics International Ag Granulado para la liberacion controlada de tamsulosina, que contiene alginato.
PL204079B1 (pl) * 2004-08-12 2009-12-31 Inst Farmaceutyczny Stały doustny preparat chlorowodorku tamsulozyny o przedłużonym uwalnianiu i sposób jego wytwarzania
US8871273B2 (en) 2005-02-25 2014-10-28 Takeda Pharmaceutical Company Limited Method for producing granules
DE102005009241A1 (de) * 2005-03-01 2006-09-07 Bayer Healthcare Ag Arzneiformen mit kontrollierter Bioverfügbarkeit
DE102005009240A1 (de) 2005-03-01 2006-09-07 Bayer Healthcare Ag Arzneiformen mit verbesserten pharmakokinetischen Eigenschaften
ITBO20050123A1 (it) * 2005-03-07 2005-06-06 Alfa Wassermann Spa Formulazioni farmaceutiche gastroresistenti contenenti rifaximina
WO2006115285A1 (ja) * 2005-04-21 2006-11-02 Takeda Pharmaceutical Company Limited 医薬組成物
CA2604617C (en) * 2005-04-28 2014-06-17 Eisai R&D Management Co., Ltd. Composition containing anti-dementia drug
US20070048369A1 (en) * 2005-08-26 2007-03-01 National Starch And Chemical Investment Holding Corporation Mucosal delivery tablet
CA2620738C (en) * 2005-08-31 2010-10-12 Ezaki Glico Co., Ltd. Tablet for removing tongue coating
US7811604B1 (en) 2005-11-14 2010-10-12 Barr Laboratories, Inc. Non-effervescent, orally disintegrating solid pharmaceutical dosage forms comprising clozapine and methods of making and using the same
JP5365777B2 (ja) 2006-09-15 2013-12-11 アステラス製薬株式会社 光に対して安定なラモセトロンの固形医薬組成物
CN101854920B (zh) 2007-10-19 2013-05-01 大塚制药株式会社 基质型药物固体制剂
AU2009214307A1 (en) * 2008-02-13 2009-08-20 Bayer Intellectual Property Gmbh Drug delivery system with stabilising effect
BRPI0908477A2 (pt) * 2008-02-13 2018-03-27 Bayer Schering Pharma Ag sistema de distribuição de medicamento contendo estradiol
JP5572321B2 (ja) * 2008-03-07 2014-08-13 沢井製薬株式会社 被覆微粒子含有口腔内崩壊錠
ES2332168B1 (es) * 2008-04-30 2010-10-27 Consejo Superior De Investigaciones Cientificas (Csic) (75%) Forma pseudopolimorfica de hidrocloruro de nicardipina, procedimiento para su preparacion y formulacion que la contiene.
EP2308483A4 (en) * 2008-07-01 2014-09-10 Sawai Seiyaku Kk PROCESS FOR PRODUCING SPHERICAL MICROPARTICLES COMPRISING TAMSULOSINE CHLORHYDRATE
CN101639340B (zh) * 2008-08-01 2011-01-12 广东省计量科学研究院 读数显微镜检定装置
MX2011003047A (es) 2008-09-24 2011-04-14 Evonik Roehm Gmbh Composicion farmaceutica de opioide de liberacion controlada ph dependiente con resistencia contra la influencia de etanol.
EP2177215A1 (en) 2008-10-17 2010-04-21 Laboratorios Del. Dr. Esteve, S.A. Co-crystals of tramadol and NSAIDs
US9284307B2 (en) 2009-08-05 2016-03-15 Idenix Pharmaceuticals Llc Macrocyclic serine protease inhibitors
UY32836A (es) 2009-08-12 2011-03-31 Bayer Schering Pharma Ag Partículas estabilizadas que comprenden 5-metil-(6s)-tetrahidrofolato
CA2771358A1 (en) 2009-08-19 2011-02-24 Sascha General Drug delivery systems (wafer) for pediatric use
TWI491395B (zh) 2009-09-30 2015-07-11 Ct Lab Inc 一種內含用以治療神經退化性疾病之立即釋出與長效釋出藥物的口服劑量配方
WO2011056764A1 (en) 2009-11-05 2011-05-12 Ambit Biosciences Corp. Isotopically enriched or fluorinated imidazo[2,1-b][1,3]benzothiazoles
MY159958A (en) 2009-12-18 2017-02-15 Idenix Pharmaceuticals Inc 5,5-fused arylene or heteroarylene hepatitis c virus inhibitors
WO2011094890A1 (en) 2010-02-02 2011-08-11 Argusina Inc. Phenylalanine derivatives and their use as non-peptide glp-1 receptor modulators
SG10201504529WA (en) * 2010-03-09 2015-07-30 Alkermes Pharma Ireland Ltd Alcohol Resistant Enteric Pharmaceutical Compositions
WO2011112689A2 (en) 2010-03-11 2011-09-15 Ambit Biosciences Corp. Saltz of an indazolylpyrrolotriazine
JP5648303B2 (ja) * 2010-03-19 2015-01-07 味の素株式会社 耐吸湿固結性を有する粉体造粒物の製造方法および粉体造粒物
KR101423237B1 (ko) * 2010-05-04 2014-07-30 주식회사 삼양바이오팜 탐스로신 또는 이의 약학적으로 허용 가능한 염을 포함하는 방출 제어용 약학 조성물, 및 이를 포함하는 경구용 제제
MX2013002383A (es) 2010-09-01 2013-07-05 Ambit Biosciences Corp Sales bromhidrato de una pirazolilaminoquinazolina.
ES2581840T3 (es) 2010-09-01 2016-09-07 Ambit Biosciences Corporation Pirazolilaminoquinazolina ópticamente activa y composiciones farmacéuticas y métodos de uso de la misma
BR112013014021A8 (pt) 2010-12-06 2017-10-03 Follica Inc Métodos para tratamento de calvície e promoção de crescimento de cabelos
WO2012080050A1 (en) 2010-12-14 2012-06-21 F. Hoffmann-La Roche Ag Solid forms of a phenoxybenzenesulfonyl compound
KR101111534B1 (ko) * 2010-12-24 2012-02-15 (주)비씨월드제약 구강 속붕해성 조성물 및 이의 제조방법
CA2825152A1 (en) 2011-01-31 2012-08-09 Celgene Corporation Pharmaceutical compositions of cytidine analogs and methods of use thereof
US9353100B2 (en) 2011-02-10 2016-05-31 Idenix Pharmaceuticals Llc Macrocyclic serine protease inhibitors, pharmaceutical compositions thereof, and their use for treating HCV infections
US20120252721A1 (en) 2011-03-31 2012-10-04 Idenix Pharmaceuticals, Inc. Methods for treating drug-resistant hepatitis c virus infection with a 5,5-fused arylene or heteroarylene hepatitis c virus inhibitor
WO2013019056A1 (en) * 2011-08-01 2013-02-07 Sam-A Pharm. Co., Ltd. Novel granule formulation containing sildenafil or pharmaceutically acceptable salts thereof as an active ingredient
ES2763579T3 (es) 2012-01-27 2020-05-29 Univ California Estabilización de biomoléculas con polímeros de azúcar
WO2013138613A1 (en) 2012-03-16 2013-09-19 Axikin Pharmaceuticals, Inc. 3,5-diaminopyrazole kinase inhibitors
KR101778050B1 (ko) * 2012-10-12 2017-09-13 이에이 파마 가부시키가이샤 칼슘 길항약/안지오텐신 ii 수용체 길항약 함유 의약 제제의 제조 방법
KR102237799B1 (ko) 2012-11-14 2021-04-08 더블유.알. 그레이스 앤드 캄파니-콘. 생물학적 활성 물질 및 비-정렬된 무기 산화물을 함유하는 조성물
CN103230379A (zh) * 2013-04-02 2013-08-07 万特制药(海南)有限公司 一种含有盐酸坦索罗辛的口崩缓释制剂及其制备方法
NZ631142A (en) 2013-09-18 2016-03-31 Axikin Pharmaceuticals Inc Pharmaceutically acceptable salts of 3,5-diaminopyrazole kinase inhibitors
EP3046924A1 (en) 2013-09-20 2016-07-27 IDENIX Pharmaceuticals, Inc. Hepatitis c virus inhibitors
WO2015134560A1 (en) 2014-03-05 2015-09-11 Idenix Pharmaceuticals, Inc. Solid forms of a flaviviridae virus inhibitor compound and salts thereof
KR20240064750A (ko) 2014-03-20 2024-05-13 카펠라 테라퓨틱스, 인크. 암 치료용의 erbb 티로신 키나제 억제제로서의 벤즈이미다졸 유도체
WO2015143161A1 (en) 2014-03-20 2015-09-24 Capella Therapeutics, Inc. Benzimidazole derivatives as erbb tyrosine kinase inhibitors for the treatment of cancer
US10335374B2 (en) * 2014-12-04 2019-07-02 University System of Georgia, Valdosta State University Tablet composition for anti-tuberculosis antibiotics
ES2805528T3 (es) 2014-12-23 2021-02-12 Sma Therapeutics Inc Inhibidores de 3,5-diaminopirazol quinasa
CZ2015225A3 (cs) * 2015-03-30 2016-10-12 Zentiva, K.S. Nový krok ve způsobu potahování pelet obsahujících Tamsulosin.HCI
JP2016193894A (ja) * 2015-04-01 2016-11-17 京都薬品工業株式会社 生菌含有製剤
JP6618736B2 (ja) 2015-09-01 2019-12-11 沢井製薬株式会社 ミラベグロン含有錠剤、ミラベグロン含有製剤の製造方法及びミラベグロン含有造粒物の製造方法
MX2018011278A (es) 2016-03-17 2019-07-08 Thiogenesis Therapeutics Inc Composiciones para la liberacion controlada de cisteamina y el tratamiento sistemico de trastornos sensibles a la cisteamina.
CN108066347B (zh) * 2016-11-16 2021-02-02 深圳万和制药有限公司 包含坦索罗辛和度他雄胺的口腔崩解片药物组合物
CN108066305B (zh) * 2016-11-16 2022-09-16 深圳万和制药有限公司 改善口崩片硬度和崩解的方法和定位释放口腔崩解片
CN108066304B (zh) * 2016-11-16 2022-09-16 深圳万和制药有限公司 具有缓释性能的坦索罗辛口腔崩解片组合物
CN108066297B (zh) * 2016-11-16 2022-09-16 深圳万和制药有限公司 治疗老年痴呆症的定位释放美金刚口腔崩解片组合物
CN107616969B (zh) * 2016-11-16 2020-09-18 杭州朱养心药业有限公司 迅速崩解的吡仑帕奈片剂药物组合物
WO2019039420A1 (ja) 2017-08-21 2019-02-28 ニプロ株式会社 医薬組成物粒子とそれを含む口腔内崩壊製剤、医薬組成物粒子の製造方法
JP7336388B2 (ja) * 2018-02-02 2023-08-31 ニプロ株式会社 錠剤及びその製造方法
EP3768240A4 (en) * 2018-03-19 2021-12-22 Cage Bio Inc. IONIC LIQUID COMPOSITIONS FOR THE TREATMENT OF ROSACEA
GB202001237D0 (en) * 2020-01-29 2020-03-11 Sisteks D O O Granular pharmaceutical product for oral administration from a pre-filled straw and method of manufacturing such pharmaceutical product

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4772475A (en) * 1985-03-08 1988-09-20 Yamanouchi Pharmaceutical Co., Ltd. Controlled-release multiple units pharmaceutical formulation
JPH0780754B2 (ja) 1986-08-06 1995-08-30 エーザイ株式会社 多顆粒型持続性錠剤
JPH01135451A (ja) * 1987-11-20 1989-05-29 Mitsubishi Electric Corp 搬送ロボット
EP0489096B1 (en) * 1989-08-25 1995-11-15 BIOGLAN IRELAND (R & D) LIMITED Pharmaceutical compositions and a device for administering the same
DE69122280T2 (de) 1990-03-01 1997-04-24 Hewlett Packard Co Minimierung von Eluatbandbreiten in der Flüssigchromatographie
EP0447168A3 (en) * 1990-03-16 1993-01-07 Yamanouchi Pharmaceutical Co. Ltd. Long acting granular pharmaceutical composition
HU219349B (en) * 1991-12-24 2001-03-28 Yamanouchi Pharma Co Ltd Intrabuccally disintegrating preparation and production thereof
US5576014A (en) 1994-01-31 1996-11-19 Yamanouchi Pharmaceutical Co., Ltd Intrabuccally dissolving compressed moldings and production process thereof
PL187160B1 (pl) 1994-01-31 2004-05-31 Yamanouchi Pharma Co Ltd Sposób wytwarzania rozpuszczalnej wewnątrzustnie formowanej tłocznie wypraski
JPH1135451A (ja) * 1994-07-27 1999-02-09 Yamanouchi Pharmaceut Co Ltd 口腔内溶解型錠剤およびその製造方法
US5824339A (en) * 1995-09-08 1998-10-20 Takeda Chemical Industries, Ltd Effervescent composition and its production
EP0922464B1 (en) 1996-07-12 2005-03-30 Daiichi Pharmaceutical Co., Ltd. Quickly disintegrable compression-molded materials and process for producing the same
JPH10182436A (ja) 1996-10-31 1998-07-07 Takeda Chem Ind Ltd 固形医薬製剤
PT1001748E (pt) 1997-07-25 2006-08-31 Alpex Pharma Sa Um processo para a preparacao de um granulado adequado para a preparacao de comprimidos rapidamente desintegraveis na boca
US6475510B1 (en) * 1997-12-19 2002-11-05 Smithkline Beecham Corporation Process for manufacturing bite-dispersion tablets
HUP0101282A3 (en) 1998-03-16 2005-03-29 Yamanouchi Pharma Tech Inc Tablets quickly disintegrating in the oral cavity and process for producing the same
US6465009B1 (en) 1998-03-18 2002-10-15 Yamanouchi Pharmaceutical Co., Ltd. Water soluble polymer-based rapidly dissolving tablets and production processes thereof
JP2000128774A (ja) * 1998-10-26 2000-05-09 Tanabe Seiyaku Co Ltd 薬物を含有する球形微粒子の製法
US6495177B1 (en) * 1999-08-13 2002-12-17 Warner Chilcott Laboratories Ireland Limited Orally dissolvable nutritional supplement
EP1269995A1 (en) 2000-03-27 2003-01-02 Kyowa Hakko Kogyo Co., Ltd. Easy-to-take granule
US6872405B2 (en) * 2001-05-10 2005-03-29 Yamanouchi Pharmaceutical Co., Ltd. Quick-disintegrating tablet in buccal cavity and manufacturing method thereof
JP4019374B2 (ja) * 2001-07-27 2007-12-12 アステラス製薬株式会社 口腔内速崩壊錠用徐放性微粒子含有組成物およびその製造法

Also Published As

Publication number Publication date
JP2005206608A (ja) 2005-08-04
CN1473035A (zh) 2004-02-04
WO2003009831A1 (en) 2003-02-06
CZ14921U1 (cs) 2004-11-23
ZA200300647B (en) 2004-07-14
DE20220604U1 (de) 2004-02-26
KR100530546B1 (ko) 2005-11-23
US20030147948A1 (en) 2003-08-07
EP1413294A4 (en) 2006-06-07
CN1473035B (zh) 2012-07-18
DE60237826D1 (de) 2010-11-11
AU2002355222B2 (en) 2007-07-26
HUP0302351A2 (hu) 2003-10-28
PL361452A1 (en) 2004-10-04
RU2245136C2 (ru) 2005-01-27
KR20030036656A (ko) 2003-05-09
JPWO2003009831A1 (ja) 2004-11-11
ES2351249T3 (es) 2011-02-02
US20070202168A1 (en) 2007-08-30
JP2004196829A (ja) 2004-07-15
US7575762B2 (en) 2009-08-18
CA2419089A1 (en) 2003-03-05
US7255876B2 (en) 2007-08-14
MXPA03000985A (es) 2004-04-02
EP1413294B1 (en) 2010-09-29
JP4019374B2 (ja) 2007-12-12
ATE482692T1 (de) 2010-10-15
HUP0302351A3 (en) 2007-03-28
EP1413294A1 (en) 2004-04-28

Similar Documents

Publication Publication Date Title
BR0205509A (pt) Composição compreendendo partìculas finas de liberação prolongada para comprimidos de rápida desintegração na cavidade bucal e método de fabricação da mesma
Mozayeni et al. Cytotoxicity of calcium enriched mixture cement compared with mineral trioxide aggregate and intermediate restorative material
NZ600640A (en) Abuse-resistant formulations
WO2008052033A3 (en) Ibuprofen composition
BRPI0707044B8 (pt) comprimido matricial insolúvel em água e processo de fabricação de comprimidos matriciais
BR0209489A (pt) Composições farmacêuticas
BRPI0608853B8 (pt) composições farmacêuticas e processo para a fabricação de microgrânulos de rifaximina gastrorresistentes
WO2003086321A3 (en) Modified release minerals
PE20061449A1 (es) Composiciones farmaceuticas comprendiendo imatinib y un retardador de liberacion
BRPI0820308A8 (pt) composições farmacêuticas
BR9811987A (pt) Comprimidos de metil celulose de rápida desintegração
MX2009008952A (es) Microesferas que comprenden una matriz de sustancia activa resistente a jugo gastrico.
NZ601200A (en) Pharmaceutical dosage forms comprising poly(epsilon-caprolactone)
MX2008012731A (es) Tabletas de paracetamol de liberacion rapida.
ATE418327T1 (de) Pharmazeutische granulatzusammensetzungen mit sofortiger freisetzung und kontinuierliches verfahren zu ihrer herstellung
TW200621267A (en) Oral disintegrative N-acetylglucosamine tablet and manufacture thereof
WO2007134158A3 (en) Granules comprising calcium carbonate, a binder and a porosity increasing agent, processes of manufacturing, use in therapy
TW200501965A (en) Highly pure fondaparinux sodium composition,process for preparing said composition and pharmaceutical compositions containing it as active principle
ATE424814T1 (de) Schnell zerfallende im mund dispergierbare zusammensetzung mit nicht-filamentösen mitverarbeiteten polyol-teilchen und verkieselter mikrokristalliner cellulose
BR9911648A (pt) Composição farmacêutica de liberação controlada e processo de liberação de agente farmaceuticamente ativo
ATE486583T1 (de) Pharmazeutische zusammensetzung enthaltend anastrozol
WO2007051542A3 (de) Kompositmaterialien aus calciumverbindungen und spezieller gelatine
WO2003063824A3 (en) Pharmaceutical composition
HRP20080452T3 (en) Orally disintegrating pharmaceutical composition comprising risperidone
AR111434A2 (es) Material granular, cápsula resistente al agua, comprimido compactado de material granular, proceso para preparar el material granular y usos

Legal Events

Date Code Title Description
B25D Requested change of name of applicant approved

Owner name: ASTELLAS PHARMA INC. (JP)

Free format text: ALTERADO DE: YAMANOUCHI PHARMACEUTICAL CO., LTD.

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 9A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2156 DE 02/05/2012.