MX2013002383A - Sales bromhidrato de una pirazolilaminoquinazolina. - Google Patents

Sales bromhidrato de una pirazolilaminoquinazolina.

Info

Publication number
MX2013002383A
MX2013002383A MX2013002383A MX2013002383A MX2013002383A MX 2013002383 A MX2013002383 A MX 2013002383A MX 2013002383 A MX2013002383 A MX 2013002383A MX 2013002383 A MX2013002383 A MX 2013002383A MX 2013002383 A MX2013002383 A MX 2013002383A
Authority
MX
Mexico
Prior art keywords
pyrazolylaminoquinazoline
hydrobromide salts
hydrobromide
salts
ameliorating
Prior art date
Application number
MX2013002383A
Other languages
English (en)
Inventor
Patrick B O'donnell
Timothy David Gross
Original Assignee
Ambit Biosciences Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ambit Biosciences Corp filed Critical Ambit Biosciences Corp
Publication of MX2013002383A publication Critical patent/MX2013002383A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/99—Enzyme inactivation by chemical treatment

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

En la presente se proporcionan las sales bromhidrato e una pirazolilaminoquinazolina, y las composiciones farmacéuticas de éstas. También se proporcionan los métodos de uso para el tratamiento, prevención y mejoría de una enfermedad proliferativa.
MX2013002383A 2010-09-01 2011-08-31 Sales bromhidrato de una pirazolilaminoquinazolina. MX2013002383A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US37929110P 2010-09-01 2010-09-01
PCT/US2011/049838 WO2012030885A1 (en) 2010-09-01 2011-08-31 Hydrobromide salts of a pyrazolylaminoquinazoline

Publications (1)

Publication Number Publication Date
MX2013002383A true MX2013002383A (es) 2013-07-05

Family

ID=44645807

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2013002383A MX2013002383A (es) 2010-09-01 2011-08-31 Sales bromhidrato de una pirazolilaminoquinazolina.

Country Status (12)

Country Link
US (1) US8633209B2 (es)
EP (1) EP2611792B1 (es)
JP (1) JP5872558B2 (es)
KR (1) KR20130141469A (es)
CN (1) CN103270030B (es)
AR (1) AR082876A1 (es)
AU (1) AU2011296046B2 (es)
CA (1) CA2809983A1 (es)
ES (1) ES2619850T3 (es)
MX (1) MX2013002383A (es)
TW (1) TW201215597A (es)
WO (1) WO2012030885A1 (es)

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Also Published As

Publication number Publication date
AU2011296046A1 (en) 2013-03-28
EP2611792A1 (en) 2013-07-10
AU2011296046B2 (en) 2015-05-14
KR20130141469A (ko) 2013-12-26
CN103270030A (zh) 2013-08-28
ES2619850T3 (es) 2017-06-27
JP2013536850A (ja) 2013-09-26
US8633209B2 (en) 2014-01-21
JP5872558B2 (ja) 2016-03-01
EP2611792B1 (en) 2017-02-01
CA2809983A1 (en) 2012-03-08
US20120053195A1 (en) 2012-03-01
TW201215597A (en) 2012-04-16
CN103270030B (zh) 2016-01-20
WO2012030885A1 (en) 2012-03-08
AR082876A1 (es) 2013-01-16

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