UY28211A1 - Compuestos de hidroximetilo - Google Patents

Compuestos de hidroximetilo

Info

Publication number
UY28211A1
UY28211A1 UY28211A UY28211A UY28211A1 UY 28211 A1 UY28211 A1 UY 28211A1 UY 28211 A UY28211 A UY 28211A UY 28211 A UY28211 A UY 28211A UY 28211 A1 UY28211 A1 UY 28211A1
Authority
UY
Uruguay
Prior art keywords
sub
hydrogen
compounds
ring
alkyl
Prior art date
Application number
UY28211A
Other languages
English (en)
Inventor
Michael Barry Gravestock
Daniel Robert Carcanague
Neil James Hales
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0304723A external-priority patent/GB0304723D0/en
Priority claimed from GB0318607A external-priority patent/GB0318607D0/en
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of UY28211A1 publication Critical patent/UY28211A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Se describen compuestos de la fórmula (i), o una sal farmacéuticamente aceptable, o un éster in-vivo hidrolizable del mismo.
UY28211A 2003-03-01 2004-02-27 Compuestos de hidroximetilo UY28211A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0304723A GB0304723D0 (en) 2003-03-01 2003-03-01 Chemical compounds
GB0318607A GB0318607D0 (en) 2003-08-08 2003-08-08 Chemical compounds

Publications (1)

Publication Number Publication Date
UY28211A1 true UY28211A1 (es) 2004-09-30

Family

ID=32964061

Family Applications (1)

Application Number Title Priority Date Filing Date
UY28211A UY28211A1 (es) 2003-03-01 2004-02-27 Compuestos de hidroximetilo

Country Status (17)

Country Link
US (1) US7192974B2 (es)
EP (1) EP1599471B1 (es)
JP (1) JP2006519247A (es)
KR (1) KR20050106064A (es)
AT (1) ATE396991T1 (es)
AU (1) AU2004218206A1 (es)
BR (1) BRPI0407835A (es)
CA (1) CA2517706A1 (es)
CL (1) CL2004000400A1 (es)
DE (1) DE602004014107D1 (es)
ES (1) ES2305732T3 (es)
HK (1) HK1083097A1 (es)
MX (1) MXPA05009205A (es)
NO (1) NO20054523L (es)
TW (1) TW200500360A (es)
UY (1) UY28211A1 (es)
WO (1) WO2004078753A1 (es)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005503435A (ja) * 2001-04-17 2005-02-03 メルク アンド カンパニー インコーポレーテッド ビシクロ［３．１．０］ヘキサン含有オキサゾリジノン抗生物質及びその誘導体
BR0308056A (pt) 2002-02-28 2004-12-07 Astrazeneca Ab Composto, pró-droga, método para a produção de um efeito antibacteriano em um animal de sangue quente, uso de um composto, composição farmacêutica, e, processo para a preparação de um composto
KR20040086465A (ko) 2002-02-28 2004-10-08 아스트라제네카 아베 화합물
US8324398B2 (en) 2003-06-03 2012-12-04 Rib-X Pharmaceuticals, Inc. Process for the synthesis of biaryl oxazolidinones
WO2005012271A2 (en) * 2003-07-29 2005-02-10 Rib-X Pharmaceuticals, Inc. Process for the synthesis of biaryl oxazolidinones
PL1656370T3 (pl) 2003-06-03 2013-03-29 Melinta Subsidiary Corp Biarylowe związki heterocykliczne oraz sposoby ich wytwarzania i stosowania
CA2529294A1 (en) * 2003-07-02 2005-01-20 Merck & Co., Inc. Oxazolidinone antibiotics and derivatives thereof
AU2004256084B2 (en) * 2003-07-02 2007-10-18 Kyorin Pharmaceutical Co., Ltd. Oxazolidinone antibiotics and derivatives thereof
JP4607107B2 (ja) * 2003-07-02 2011-01-05 メルク・シャープ・エンド・ドーム・コーポレイション シクロプロピル基置換されたオキサゾリジノン抗生物質およびこれらの誘導体
WO2005005420A1 (en) * 2003-07-02 2005-01-20 Merck & Co., Inc. Cyclopropyl group substituted oyazolidinone antibiotics and derivatives thereof
ES2536001T3 (es) * 2003-07-29 2015-05-19 Melinta Therapeutics, Inc. Procedimiento para la síntesis de biariloxazolidinonas
EP1669348A4 (en) * 2003-09-30 2009-03-11 Eisai R&D Man Co Ltd NEW ANTIPILIC AGENT CONTAINING A HETEROCYCLIC COMPOUND
TW200526649A (en) 2003-12-17 2005-08-16 Rib X Pharmaceuticals Inc Halogenated biaryl heterocyclic compounds and methods of making and using the same
KR100854211B1 (ko) * 2003-12-18 2008-08-26 동아제약주식회사 신규한 옥사졸리디논 유도체, 그의 제조방법 및 이를유효성분으로 하는 항생제용 약학 조성물
US20050241110A1 (en) * 2004-04-09 2005-11-03 Bruce Baker Ergonomic handles, especially for garden tools
US20080064689A1 (en) * 2004-05-25 2008-03-13 Astrazeneca Ab 3-[4-(6-Pyridin-3-Yl)-3-Phenyl] -5-(1H-1,2,3-Triazol-1-Ylmethyl)-1,3-Oxazolidin-2-Ones as Antibacterial Agents
GB0411596D0 (en) * 2004-05-25 2004-06-30 Astrazeneca Ab Chemical process
US20070208062A1 (en) * 2004-05-25 2007-09-06 Astrazeneca Ab 3-(4-(2-dihydroisoxazol-3-ylpyridin-5-yl)phenyl)-5-triazol-1-ylmethyloxazolidin-2-one derivatives as mao inhibitors for the treatment of bacterial infections
EP1799677A1 (en) * 2004-10-08 2007-06-27 Ranbaxy Laboratories Limited Oxazolidinone derivatives as antimicrobials
EP1864980A4 (en) 2005-03-30 2010-08-18 Eisai R&D Man Co Ltd A PYRIDINE DERIVATIVE ANTIPILIC AGENT
US8399660B2 (en) * 2005-06-08 2013-03-19 Rib-X Pharmaceuticals, Inc. Process for the synthesis of triazoles
TWI385169B (zh) 2005-10-31 2013-02-11 Eisai R&D Man Co Ltd 經雜環取代之吡啶衍生物及含有彼之抗真菌劑
WO2007052479A1 (ja) * 2005-11-04 2007-05-10 Ngk Insulators, Ltd. ハニカム構造体及びハニカム触媒体
US8119667B2 (en) * 2005-12-29 2012-02-21 Schering-Plough Animal Health Corporation Carbonates of fenicol antibiotics
EP2065377B1 (en) 2006-09-21 2011-11-23 Eisai R&D Management Co., Ltd. Pyridine derivative substituted by heteroaryl ring, and antifungal agent comprising the same
US8258394B2 (en) * 2007-02-08 2012-09-04 Bradford G Baruh Retractable solar panel system
US20080190341A1 (en) * 2007-02-08 2008-08-14 Baruh Bradford G System and method of adjusting the location and position of the foresail on a sailboat
US20100065104A1 (en) * 2007-08-31 2010-03-18 Baruh Bradford G Retractable solar panel system
KR100848232B1 (ko) * 2007-04-12 2008-07-24 일동제약주식회사 신규 헤테로 고리 또는 알콕시아미노메틸 옥사졸리디논 및그 제조방법
KR20100015897A (ko) * 2007-04-27 2010-02-12 에자이 알앤드디 매니지먼트 가부시키가이샤 헤테로환 치환 피리딘 유도체의 염 또는 그의 결정
TW200841879A (en) 2007-04-27 2008-11-01 Eisai R&D Man Co Ltd Pyridine derivatives substituted by heterocyclic ring and phosphonoamino group, and anti-fungal agent containing same
EP2166838B1 (en) * 2007-06-01 2018-10-24 CHX Technologies Inc. Topical dental solution of chlorhexidine in sumatra benzoin bp/ep and methods of manufacturing and evaluating same
US8513287B2 (en) 2007-12-27 2013-08-20 Eisai R&D Management Co., Ltd. Heterocyclic ring and phosphonoxymethyl group substituted pyridine derivatives and antifungal agent containing same
US20100048524A1 (en) 2008-03-14 2010-02-25 Angela Brodie Novel C-17-Heteroaryl Steroidal CYP17 Inhibitors/Antiandrogens;Synthesis In Vitro Biological Activities, Pharmacokinetics and Antitumor Activity
US20110118219A1 (en) * 2008-03-25 2011-05-19 University Of Maryland, Baltimore Novel prodrugs of c-17-heteroaryl steroidal cyp17 inhibitors/antiandrogens: synthesis, in vitro biological activities, pharmacokinetics and antitumor activity
NZ587096A (en) 2008-03-26 2011-11-25 Global Alliance For Tb Drug Dev Bicyclic nitroimidazoles covalently linked to substituted phenyl oxazolidinones
EP2757104B1 (en) 2008-10-10 2019-08-14 Merck Sharp & Dohme Corp. Compounds used in the synthesis of oxazolidinones
US8188119B2 (en) 2008-10-24 2012-05-29 Eisai R&D Management Co., Ltd Pyridine derivatives substituted with heterocyclic ring and γ-glutamylamino group, and antifungal agents containing same
EP2393808B1 (en) 2009-02-03 2019-05-08 Merck Sharp & Dohme Corp. Crystalline form of r)-3-(4-(2-(2-methyltetrazol-5-yl)pyridin-5-yl)-3-fluorophenyl)-5-hydroxymethyl oxazolidin-2-one dihydrogen phosphate
JP2012516900A (ja) 2009-02-05 2012-07-26 トーカイ ファーマシューティカルズ，インク． ステロイド性ｃｙｐ１７阻害剤／抗アンドロゲン剤の新しいプロドラッグ
CN102348696B (zh) * 2009-03-13 2015-06-17 太阳化学有限公司 可用于可能量固化的组合物中的环状氨基甲酸酯化合物
US8580767B2 (en) * 2009-05-28 2013-11-12 Trius Therapeutics, Inc. Oxazolidinone containing dimer compounds, compositions and methods to make and use
KR101653570B1 (ko) * 2011-03-30 2016-09-02 주식회사 레고켐 바이오사이언스 신규한 옥사졸리디논 유도체 및 이를 함유하는 의약 조성물
EP2626356A1 (en) * 2012-02-08 2013-08-14 Rheinische Friedrich-Wilhelms-Universität Bonn Thiamine analogues and their use as antibiotics
BR112015023098A2 (pt) 2013-03-14 2017-07-18 Univ Jefferson agentes de infrarregulação do receptor de andrógeno e usos dos mesmos
JP2016528252A (ja) 2013-08-12 2016-09-15 トーカイ ファーマシューティカルズ， インコーポレイテッド アンドロゲン標的治療を使用する新生物障害の処置のためのバイオマーカー
CN112707779B (zh) * 2020-12-26 2023-06-30 蚌埠中实化学技术有限公司 一种乙烯基环己烷的制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4948801A (en) * 1988-07-29 1990-08-14 E. I. Du Pont De Nemours And Company Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents
WO1993009103A1 (en) * 1991-11-01 1993-05-13 The Upjohn Company Substituted aryl- and heteroarylphenyloxazolidinones useful as antibacterial agents
JP2003535860A (ja) * 2000-06-05 2003-12-02 ドン・ア・ファーム・カンパニー・リミテッド 新規なオキサゾリジノン誘導体及びその製造方法
US20020115669A1 (en) * 2000-08-31 2002-08-22 Wiedeman Paul E. Oxazolidinone chemotherapeutic agents
CN1639136A (zh) * 2001-09-11 2005-07-13 阿斯特拉曾尼卡有限公司 作为抗菌剂的噁唑烷酮和/或异噁唑啉
GB0227701D0 (en) * 2002-11-28 2003-01-08 Astrazeneca Ab Chemical compounds
US20060116400A1 (en) * 2002-11-28 2006-06-01 Astrazeneca Ab Oxazolidinone and/or isoxazoline derivatives as antibacterial agents
GB0229526D0 (en) * 2002-12-19 2003-01-22 Astrazeneca Ab Chemical compounds

Also Published As

Publication number Publication date
HK1083097A1 (en) 2006-06-23
EP1599471A1 (en) 2005-11-30
ATE396991T1 (de) 2008-06-15
AU2004218206A1 (en) 2004-09-16
CA2517706A1 (en) 2004-09-16
KR20050106064A (ko) 2005-11-08
CL2004000400A1 (es) 2005-04-22
US20060270637A1 (en) 2006-11-30
WO2004078753A1 (en) 2004-09-16
NO20054523L (no) 2005-12-01
BRPI0407835A (pt) 2006-02-14
US7192974B2 (en) 2007-03-20
MXPA05009205A (es) 2005-10-18
NO20054523D0 (no) 2005-09-30
EP1599471B1 (en) 2008-05-28
DE602004014107D1 (de) 2008-07-10
TW200500360A (en) 2005-01-01
ES2305732T3 (es) 2008-11-01
JP2006519247A (ja) 2006-08-24

Similar Documents

Publication Publication Date Title
UY28211A1 (es) Compuestos de hidroximetilo
WO2007016392A3 (en) Benzothiazole and azabenzothiazole compounds useful as kinase inhibitors
GB0129476D0 (en) Organic compounds
NO20083207L (no) Inhibitorer av IAP
WO2005092858A3 (en) Alpha aryl or heteroaryl methyl beta piperidino propanamide compounds as orl1-receptor antagonist
UA83243C2 (ru) Соединения, которые ингибируют натриезависимый переносчик глюкозы
GB0123589D0 (en) Organic compounds
ATE369370T1 (de) Substituierte 2h-(1,2,4)triazolo(4,3-a)pyrazine als gsk-3-inhibitoren
MY132698A (en) Herbicidal composition
MXPA05009969A (es) Metodo para aislar la forma cristalina i de la 5-azacitidina.
EA200600225A1 (ru) Производные пиперазина для лечения вич инфекций
NO20024614L (no) N-heterosykliske derivater som NOS-hemmere
MXPA05012268A (es) N-arilsulfonilpiperidinas enlazadas como inhibidores de la gamma-secretasa.
MXPA05012837A (es) Inhibidores de caspasa y usos de los mismos.
MA27549A1 (fr) N-sulfonyl-4-methylene-amino-3-hydroxy-2-pyridones
WO2005003087A3 (en) Oxazole derivatives as antibacterial agents
RS97004A (en) Benzoxazine derivatives as 5-ht6 modulators and uses thereof
ATE304536T1 (de) Bicyclo(3,1,0)hexan als strukturelement enthaltende oxazolidinon-antibiotika und deren derivate
ATE453389T1 (de) Bestimmte pharmazeutisch wertvolle substituierte aminoalkyl-heterocyclen
GEP20074256B (en) Novel benzothiadiazine, process for their preparation and pharmaceutical compositions containing
WO2007014839A3 (en) Cathepsin k inhibitors
WO2003072576A3 (en) Oxazolidinone derivatives, processes for their preparation, and pharmaceutical compositions containing them
MXPA04008926A (es) Inhibidores de entrada a moleculas pequenas.
ATE449773T1 (de) Homomorpholinoxazolidinone als antibakterielle mittel
EA200501696A1 (ru) Новые соединения тиадиазина, способ их получения и фармацевтические композиции, которые их содержат

Legal Events

Date Code Title Description
109 Application deemed to be withdrawn

Effective date: 20140915