MA27549A1 - N-sulfonyl-4-methylene-amino-3-hydroxy-2-pyridones - Google Patents

N-sulfonyl-4-methylene-amino-3-hydroxy-2-pyridones

Info

Publication number
MA27549A1
MA27549A1 MA28270A MA28270A MA27549A1 MA 27549 A1 MA27549 A1 MA 27549A1 MA 28270 A MA28270 A MA 28270A MA 28270 A MA28270 A MA 28270A MA 27549 A1 MA27549 A1 MA 27549A1
Authority
MA
Morocco
Prior art keywords
pyridone
sulfonyl
methylene
hydroxy
amino
Prior art date
Application number
MA28270A
Other languages
English (en)
Inventor
Namal Chithranga Warshakoon
Rodney Dean Bush
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Publication of MA27549A1 publication Critical patent/MA27549A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

La présente invention concerne des composés de formule (I) efficaces pour traiter une infection microbienne.
MA28270A 2002-11-09 2005-05-09 N-sulfonyl-4-methylene-amino-3-hydroxy-2-pyridones MA27549A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US42507102P 2002-11-09 2002-11-09

Publications (1)

Publication Number Publication Date
MA27549A1 true MA27549A1 (fr) 2005-10-03

Family

ID=32312927

Family Applications (1)

Application Number Title Priority Date Filing Date
MA28270A MA27549A1 (fr) 2002-11-09 2005-05-09 N-sulfonyl-4-methylene-amino-3-hydroxy-2-pyridones

Country Status (25)

Country Link
US (3) US6946479B2 (fr)
EP (1) EP1558580B1 (fr)
JP (1) JP4327730B2 (fr)
KR (2) KR100894237B1 (fr)
CN (1) CN1708482A (fr)
AT (1) ATE372986T1 (fr)
AU (1) AU2003296045B2 (fr)
BR (1) BR0316086A (fr)
CA (1) CA2502416C (fr)
CO (1) CO5570702A2 (fr)
CY (1) CY1106957T1 (fr)
DE (1) DE60316339T2 (fr)
DK (1) DK1558580T3 (fr)
ES (1) ES2293059T3 (fr)
HR (1) HRP20050517B1 (fr)
IL (1) IL168118A (fr)
MA (1) MA27549A1 (fr)
MX (1) MXPA05004897A (fr)
NO (1) NO331012B1 (fr)
NZ (1) NZ539385A (fr)
PL (1) PL377176A1 (fr)
PT (1) PT1558580E (fr)
RU (1) RU2321584C2 (fr)
WO (1) WO2004043928A2 (fr)
ZA (1) ZA200503682B (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6946479B2 (en) * 2002-11-09 2005-09-20 The Procter & Gamble Company N-sulfonyl-4-methyleneamino-3-hydroxy-2-pyridones
US6930117B2 (en) * 2002-11-09 2005-08-16 The Procter & Gamble Company N-alkyl-4-methyleneamino-3-hydroxy-2-pyridones
US20070275944A1 (en) * 2006-04-05 2007-11-29 The Board Of Trustees Operating Michigan State University Antioxidants and methods of their use
US7622593B2 (en) 2006-06-27 2009-11-24 The Procter & Gamble Company Human protein tyrosine phosphatase inhibitors and methods of use
MX2011007420A (es) 2009-07-06 2011-12-14 Akebia Therapeutics Inc Compuestos, composiciones y metodos para prevenir la metastasis de las celulas cancerigenas.
US8536181B2 (en) 2009-11-06 2013-09-17 Aerpio Therapeutics Inc. Prolyl hydroxylase inhibitors
EP2804604A1 (fr) 2011-10-31 2014-11-26 The Methodist Hospital Research Institute Composé comprenant un fragment de ciblage/recherche de mao pour le traitement de gliomes humains
CN103360308A (zh) * 2012-03-28 2013-10-23 孙伟新 1,4-二羟基-6-甲基-2-吡啶酮类化合物及其制备方法和用途
US20150050277A1 (en) 2013-03-15 2015-02-19 Aerpio Therapeutics Inc. Compositions and methods for treating ocular diseases
JP6572201B2 (ja) 2013-03-15 2019-09-04 エアーピオ セラピューティクス インコーポレイテッド 眼疾患を処置するための組成物、製剤、および方法
US9388135B2 (en) 2014-02-19 2016-07-12 Aerpio Therapeutics, Inc. Process for preparing N-benzyl-3-hydroxy-4-substituted-pyridin-2-(1H)-ones
CN106456614A (zh) 2014-03-14 2017-02-22 爱尔皮奥治疗有限公司 HPTP‑β抑制剂
US9539245B2 (en) 2014-08-07 2017-01-10 Aerpio Therapeutics, Inc. Combination of immunotherapies with activators of Tie-2

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3853900A (en) 1973-09-14 1974-12-10 Searle & Co 4-benzyloxy-2 (1h)-pyridones
US5358949A (en) 1986-03-05 1994-10-25 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivatives and salts thereof and anti-arrhythmic agents containing the carbostyril derivatives
DE4316077A1 (de) 1993-05-13 1994-11-17 Bayer Ag Substituierte Mono- und Bihydridylmethylpyridone
US5789426A (en) 1995-01-20 1998-08-04 Cornell Research Foundation, Inc. Method for the treatment of fibroproliferative disorders by application of inhibitors of protein hydroxylation
US6046219A (en) 1995-01-20 2000-04-04 Cornell Research Foundation, Inc. Method for the treatment of conditions mediated by collagen formation together with cell proliferation by application of inhibitors of protein hydroxylation
US5849587A (en) 1995-06-09 1998-12-15 Cornell Research Foundation, Inc. Method of inhibiting viral replication in eukaryotic cells and of inducing apoptosis of virally-infected cells
US6946479B2 (en) * 2002-11-09 2005-09-20 The Procter & Gamble Company N-sulfonyl-4-methyleneamino-3-hydroxy-2-pyridones

Also Published As

Publication number Publication date
KR100894237B1 (ko) 2009-04-20
US20050256126A1 (en) 2005-11-17
CY1106957T1 (el) 2012-09-26
RU2005114490A (ru) 2006-01-20
JP2006513164A (ja) 2006-04-20
WO2004043928A2 (fr) 2004-05-27
US20070238722A1 (en) 2007-10-11
JP4327730B2 (ja) 2009-09-09
AU2003296045B2 (en) 2008-04-03
WO2004043928A8 (fr) 2005-05-06
ZA200503682B (en) 2006-11-29
NZ539385A (en) 2008-02-29
HRP20050517B1 (hr) 2014-03-14
ES2293059T3 (es) 2008-03-16
EP1558580A2 (fr) 2005-08-03
AU2003296045A1 (en) 2004-06-03
PT1558580E (pt) 2007-12-06
US6946479B2 (en) 2005-09-20
CA2502416A1 (fr) 2004-05-27
US20040097559A1 (en) 2004-05-20
CN1708482A (zh) 2005-12-14
DE60316339D1 (de) 2007-10-25
HRP20050517A2 (en) 2005-12-31
DE60316339T2 (de) 2008-06-05
IL168118A (en) 2011-07-31
CA2502416C (fr) 2010-07-20
ATE372986T1 (de) 2007-09-15
PL377176A1 (pl) 2006-01-23
NO331012B1 (no) 2011-09-05
EP1558580B1 (fr) 2007-09-12
KR20050055793A (ko) 2005-06-13
RU2321584C2 (ru) 2008-04-10
US7247632B2 (en) 2007-07-24
NO20052788L (no) 2005-06-09
WO2004043928A3 (fr) 2004-07-01
DK1558580T3 (da) 2008-01-14
MXPA05004897A (es) 2005-11-17
CO5570702A2 (es) 2005-10-31
KR20070030334A (ko) 2007-03-15
BR0316086A (pt) 2005-09-27

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