UY27742A1 - Derivados de quinazolina - Google Patents
Derivados de quinazolinaInfo
- Publication number
- UY27742A1 UY27742A1 UY27742A UY27742A UY27742A1 UY 27742 A1 UY27742 A1 UY 27742A1 UY 27742 A UY27742 A UY 27742A UY 27742 A UY27742 A UY 27742A UY 27742 A1 UY27742 A1 UY 27742A1
- Authority
- UY
- Uruguay
- Prior art keywords
- quinazoline derivatives
- tumors
- medicament
- inhibition
- prevention
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Abstract
La invención se refiere a un derivado de quinazolinas de fórmula I en donde cada uno de Q1, Z, R1, y Q2, tienen cualquiera de los sentidos definidos en la descripción; procesos para su preparación, composiciones farmacéuticas que los contienen y su uso en la fabricación de un medicamento para uso como agente antiproliferativo en la prevención o tratamiento de tumores que son sensibles a la inhibición de las tirosinquinasas receptoras erbB.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0207323A GB0207323D0 (en) | 2002-03-28 | 2002-03-28 | Compounds |
GB0230086A GB0230086D0 (en) | 2002-12-24 | 2002-12-24 | Compounds |
GB0301916A GB0301916D0 (en) | 2003-01-28 | 2003-01-28 | Compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
UY27742A1 true UY27742A1 (es) | 2003-10-31 |
Family
ID=28678580
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UY27742A UY27742A1 (es) | 2002-03-28 | 2003-03-28 | Derivados de quinazolina |
Country Status (29)
Country | Link |
---|---|
US (4) | US20050215574A1 (es) |
EP (1) | EP1487806B1 (es) |
JP (2) | JP3891493B2 (es) |
KR (1) | KR101006947B1 (es) |
CN (1) | CN100439344C (es) |
AR (1) | AR039203A1 (es) |
AT (1) | ATE473215T1 (es) |
AU (1) | AU2003214443B8 (es) |
BR (1) | BR0308670A (es) |
CA (1) | CA2479642C (es) |
CY (1) | CY1111039T1 (es) |
DE (1) | DE60333262D1 (es) |
DK (1) | DK1487806T3 (es) |
ES (1) | ES2346135T3 (es) |
HK (2) | HK1070888A1 (es) |
IL (2) | IL164135A0 (es) |
IS (1) | IS2855B (es) |
MX (1) | MXPA04009486A (es) |
MY (1) | MY158054A (es) |
NO (1) | NO329542B1 (es) |
NZ (1) | NZ535014A (es) |
PL (1) | PL214880B1 (es) |
PT (1) | PT1487806E (es) |
SA (1) | SA03240080B1 (es) |
SI (1) | SI1487806T1 (es) |
TW (2) | TW200813014A (es) |
UA (1) | UA78302C2 (es) |
UY (1) | UY27742A1 (es) |
WO (1) | WO2003082831A1 (es) |
Families Citing this family (69)
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US20030235890A1 (en) * | 2001-11-19 | 2003-12-25 | David Wyllie | Functional polymorphisms of the interleukin-1 locus affecting transcription and susceptibility to inflammatory and infectious diseases |
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US7019012B2 (en) * | 2000-12-20 | 2006-03-28 | Boehringer Ingelheim International Pharma Gmbh & Co. Kg | Quinazoline derivatives and pharmaceutical compositions containing them |
PL369938A1 (en) * | 2001-11-03 | 2005-05-02 | Astrazeneca Ab | Quinazoline derivatives as antitumor agents |
GB0126433D0 (en) * | 2001-11-03 | 2002-01-02 | Astrazeneca Ab | Compounds |
TW200813014A (en) * | 2002-03-28 | 2008-03-16 | Astrazeneca Ab | Quinazoline derivatives |
CN1642552B (zh) * | 2002-03-30 | 2010-05-12 | 贝林格尔英格海姆法玛两合公司 | 作为酪氨酸激酶抑制剂的4-(n-苯氨基)-喹唑啉/喹啉 |
DE10214412A1 (de) * | 2002-03-30 | 2003-10-09 | Boehringer Ingelheim Pharma | Bicyclische Heterocyclen, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Verfahren zu ihrer Herstellung |
US6924285B2 (en) * | 2002-03-30 | 2005-08-02 | Boehringer Ingelheim Pharma Gmbh & Co. | Bicyclic heterocyclic compounds, pharmaceutical compositions containing these compounds, their use and process for preparing them |
DE10221018A1 (de) * | 2002-05-11 | 2003-11-27 | Boehringer Ingelheim Pharma | Verwendung von Hemmern der EGFR-vermittelten Signaltransduktion zur Behandlung von gutartiger Prostatahyperplasie (BPH)/Prostatahypertrophie |
US7576074B2 (en) | 2002-07-15 | 2009-08-18 | Rice Kenneth D | Receptor-type kinase modulators and methods of use |
GB0309009D0 (en) * | 2003-04-22 | 2003-05-28 | Astrazeneca Ab | Quinazoline derivatives |
GB0309850D0 (en) * | 2003-04-30 | 2003-06-04 | Astrazeneca Ab | Quinazoline derivatives |
GB0317665D0 (en) * | 2003-07-29 | 2003-09-03 | Astrazeneca Ab | Qinazoline derivatives |
KR20060054388A (ko) * | 2003-07-29 | 2006-05-22 | 아스트라제네카 아베 | 티로신 키나아제 억제제로서의 피페리딜-퀴나졸린 유도체 |
JP2007505873A (ja) * | 2003-09-16 | 2007-03-15 | アストラゼネカ アクチボラグ | チロシンキナーゼ阻害剤としてのキナゾリン誘導体 |
EP1667996B1 (en) * | 2003-09-16 | 2009-07-22 | Astrazeneca AB | Quinazoline derivatives |
RU2378268C2 (ru) * | 2003-09-16 | 2010-01-10 | Астразенека Аб | Производные хиназолина в качестве ингибиторов тирозинкиназы |
GB0321648D0 (en) * | 2003-09-16 | 2003-10-15 | Astrazeneca Ab | Quinazoline derivatives |
WO2005026156A1 (en) * | 2003-09-16 | 2005-03-24 | Astrazeneca Ab | Quinazoline derivatives |
PL1667992T3 (pl) * | 2003-09-19 | 2007-05-31 | Astrazeneca Ab | Pochodne chinazoliny |
DE602004004811T2 (de) * | 2003-09-19 | 2007-11-22 | Astrazeneca Ab | Chinazolinderivate |
GB0322409D0 (en) * | 2003-09-25 | 2003-10-29 | Astrazeneca Ab | Quinazoline derivatives |
WO2005030757A1 (en) * | 2003-09-25 | 2005-04-07 | Astrazeneca Ab | Quinazoline derivatives |
MXPA06005024A (es) * | 2003-11-06 | 2006-07-06 | Pfizer Prod Inc | Combinaciones de inhibidor de erbb2 selectivo/anticuerpos anti-erbb en el tratamiento del cancer. |
GB0326459D0 (en) * | 2003-11-13 | 2003-12-17 | Astrazeneca Ab | Quinazoline derivatives |
EP1713781B1 (en) * | 2004-02-03 | 2008-11-05 | AstraZeneca AB | Quinazoline derivatives |
KR100885835B1 (ko) | 2004-05-06 | 2009-02-26 | 워너-램버트 캄파니 엘엘씨 | 4-페닐아미노-퀴나졸린-6-일-아미드 |
JP2008501675A (ja) * | 2004-06-04 | 2008-01-24 | アストラゼネカ アクチボラグ | Erbb受容体型チロシンキナーゼとしてのキナゾリン誘導体 |
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GB0504474D0 (en) * | 2005-03-04 | 2005-04-13 | Astrazeneca Ab | Chemical compounds |
GB0508717D0 (en) * | 2005-04-29 | 2005-06-08 | Astrazeneca Ab | Chemical compounds |
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