UA117466C2 - СТАБІЛЬНИЙ СКЛАД У ВИГЛЯДІ РОЗЧИНУ АНТИТІЛА ДО IL-23p19 - Google Patents

СТАБІЛЬНИЙ СКЛАД У ВИГЛЯДІ РОЗЧИНУ АНТИТІЛА ДО IL-23p19

Info

Publication number
UA117466C2
UA117466C2 UAA201506824A UAA201506824A UA117466C2 UA 117466 C2 UA117466 C2 UA 117466C2 UA A201506824 A UAA201506824 A UA A201506824A UA A201506824 A UAA201506824 A UA A201506824A UA 117466 C2 UA117466 C2 UA 117466C2
Authority
UA
Ukraine
Prior art keywords
antibodies
solution formulations
engineered anti
solution
relates
Prior art date
Application number
UAA201506824A
Other languages
English (en)
Inventor
Рамеш С. Каші
Анікет Бадкар
Original Assignee
Мерк Шарп Енд Доме Корп.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=50934859&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UA117466(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Мерк Шарп Енд Доме Корп. filed Critical Мерк Шарп Енд Доме Корп.
Publication of UA117466C2 publication Critical patent/UA117466C2/uk

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39591—Stabilisation, fragmentation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/51—Complete heavy chain or Fd fragment, i.e. VH + CH1
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/515—Complete light chain, i.e. VL + CL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance

Abstract

Винахід стосується стабільного складу у вигляді розчину антитіла hum13B8-b до IL-23p19. Винахід також стосується способу лікування аутоімунного, запального або проліферативного захворювання, способу лікування псоріазу та застосування стабільного складу у вигляді розчину у виробництві лікарського препарату.
UAA201506824A 2012-12-13 2013-09-12 СТАБІЛЬНИЙ СКЛАД У ВИГЛЯДІ РОЗЧИНУ АНТИТІЛА ДО IL-23p19 UA117466C2 (uk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261737035P 2012-12-13 2012-12-13
PCT/US2013/073825 WO2014093203A1 (en) 2012-12-13 2013-12-09 SOLUTION FORMULATIONS OF ENGINEERED ANTI-IL-23p19 ANTIBODIES

Publications (1)

Publication Number Publication Date
UA117466C2 true UA117466C2 (uk) 2018-08-10

Family

ID=50934859

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA201506824A UA117466C2 (uk) 2012-12-13 2013-09-12 СТАБІЛЬНИЙ СКЛАД У ВИГЛЯДІ РОЗЧИНУ АНТИТІЛА ДО IL-23p19

Country Status (31)

Country Link
US (2) US20150329632A1 (uk)
EP (1) EP2931313B1 (uk)
JP (1) JP6266012B2 (uk)
KR (1) KR102004585B1 (uk)
CN (1) CN104870016B (uk)
AU (1) AU2013359767B2 (uk)
BR (1) BR112015013540B1 (uk)
CA (1) CA2894869C (uk)
CL (1) CL2015001608A1 (uk)
CY (1) CY1121895T1 (uk)
DK (1) DK2931313T3 (uk)
EA (1) EA034616B1 (uk)
ES (1) ES2732861T3 (uk)
HK (1) HK1215194A1 (uk)
HR (1) HRP20191137T1 (uk)
HU (1) HUE045668T2 (uk)
IL (3) IL278295B2 (uk)
LT (1) LT2931313T (uk)
MX (1) MX357936B (uk)
MY (1) MY187921A (uk)
NZ (1) NZ708443A (uk)
PE (1) PE20151524A1 (uk)
PH (1) PH12015501296B1 (uk)
PL (1) PL2931313T3 (uk)
PT (1) PT2931313T (uk)
RS (1) RS59057B1 (uk)
SI (1) SI2931313T1 (uk)
TR (1) TR201909584T4 (uk)
UA (1) UA117466C2 (uk)
WO (1) WO2014093203A1 (uk)
ZA (1) ZA201504408B (uk)

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JP7179717B2 (ja) * 2017-03-31 2022-11-29 Ｍｅｉｊｉ Ｓｅｉｋａファルマ株式会社 水性製剤及び注射器入り水性製剤、並びに、抗体タンパク脱凝集剤及び抗体タンパク脱凝集方法
JP2021515770A (ja) * 2018-03-05 2021-06-24 ヤンセン バイオテツク，インコーポレーテツド 抗ｉｌ−２３特異的抗体を用いたクローン病の治療方法
KR20210093976A (ko) * 2018-11-21 2021-07-28 리제너론 파아마슈티컬스, 인크. 고농도 단백질 제형
MA55033A (fr) 2019-02-18 2021-12-29 Lilly Co Eli Formulation d'anticorps thérapeutique
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JP2022534020A (ja) 2019-05-23 2022-07-27 ヤンセン バイオテツク，インコーポレーテツド Ｉｌ－２３及びｔｎｆアルファに対する抗体の併用療法による炎症性腸疾患の治療方法
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CN115605231A (zh) * 2020-05-13 2023-01-13 信达生物制药（苏州）有限公司（Cn） 包含抗IL-23p19抗体的制剂、其制备方法和用途

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Also Published As

Publication number Publication date
EP2931313A1 (en) 2015-10-21
KR102004585B1 (ko) 2019-07-26
PH12015501296A1 (en) 2015-08-24
TR201909584T4 (tr) 2019-07-22
PE20151524A1 (es) 2015-11-06
AU2013359767B2 (en) 2018-04-05
AU2013359767A1 (en) 2015-07-23
EP2931313A4 (en) 2016-08-03
NZ708443A (en) 2018-05-25
CY1121895T1 (el) 2020-10-14
CL2015001608A1 (es) 2015-10-30
JP6266012B2 (ja) 2018-01-24
IL239150B (en) 2020-11-30
HUE045668T2 (hu) 2020-01-28
LT2931313T (lt) 2019-09-25
IL307581A (en) 2023-12-01
MY187921A (en) 2021-10-28
SI2931313T1 (sl) 2019-09-30
CN104870016B (zh) 2018-05-08
CA2894869C (en) 2021-06-15
CN104870016A (zh) 2015-08-26
IL278295B2 (en) 2024-03-01
IL239150A0 (en) 2015-07-30
EA034616B1 (ru) 2020-02-27
BR112015013540B1 (pt) 2021-04-27
ES2732861T3 (es) 2019-11-26
EA201591133A1 (ru) 2015-10-30
DK2931313T3 (da) 2019-07-15
PL2931313T3 (pl) 2019-10-31
MX2015007213A (es) 2016-08-03
CA2894869A1 (en) 2014-06-19
KR20150092763A (ko) 2015-08-13
HK1215194A1 (zh) 2016-08-19
PH12015501296B1 (en) 2015-08-24
JP2016505572A (ja) 2016-02-25
US20210188964A1 (en) 2021-06-24
ZA201504408B (en) 2017-09-27
IL278295B1 (en) 2023-11-01
MX357936B (es) 2018-07-31
RS59057B1 (sr) 2019-08-30
PT2931313T (pt) 2019-07-10
WO2014093203A1 (en) 2014-06-19
HRP20191137T1 (hr) 2019-09-20
BR112015013540A2 (pt) 2017-11-14
EP2931313B1 (en) 2019-05-08
BR112015013540A8 (pt) 2018-04-17
IL278295A (uk) 2020-12-31
US20150329632A1 (en) 2015-11-19

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