CY1120646T1 - Προγονικα κυτταρα μεσοδερμικης προελευσης - Google Patents
Προγονικα κυτταρα μεσοδερμικης προελευσηςInfo
- Publication number
- CY1120646T1 CY1120646T1 CY181100736T CY181100736T CY1120646T1 CY 1120646 T1 CY1120646 T1 CY 1120646T1 CY 181100736 T CY181100736 T CY 181100736T CY 181100736 T CY181100736 T CY 181100736T CY 1120646 T1 CY1120646 T1 CY 1120646T1
- Authority
- CY
- Cyprus
- Prior art keywords
- origin
- intermederal
- original cells
- cells
- original
- Prior art date
Links
- 210000000130 stem cell Anatomy 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0665—Blood-borne mesenchymal stem cells, e.g. from umbilical cord blood
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0645—Macrophages, e.g. Kuepfer cells in the liver; Monocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/15—Cells of the myeloid line, e.g. granulocytes, basophils, eosinophils, neutrophils, leucocytes, monocytes, macrophages or mast cells; Myeloid precursor cells; Antigen-presenting cells, e.g. dendritic cells
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/02—Atmosphere, e.g. low oxygen conditions
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/70—Undefined extracts
- C12N2500/80—Undefined extracts from animals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/11—Coculture with; Conditioned medium produced by blood or immune system cells
- C12N2502/115—Platelets, megakaryocytes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/11—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from blood or immune system cells
- C12N2506/115—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from blood or immune system cells from monocytes, from macrophages
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Developmental Biology & Embryology (AREA)
- Cell Biology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Gastroenterology & Hepatology (AREA)
- Ophthalmology & Optometry (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
Abstract
Η εφεύρεση αφορά προγονικά κύτταρα μεσοδερμικής προέλευσης και τη θεραπευτική χρήση τους.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB1111500.3A GB201111500D0 (en) | 2011-07-06 | 2011-07-06 | Wet age-related macular degeneration MSC subtype |
GBGB1111505.2A GB201111505D0 (en) | 2011-07-06 | 2011-07-06 | MI MSC subtype |
GBGB1111503.7A GB201111503D0 (en) | 2011-07-06 | 2011-07-06 | Heart failure (HF) MSC subtype |
GBGB1111509.4A GB201111509D0 (en) | 2011-07-06 | 2011-07-06 | Orthopedic MSC subtype |
PCT/GB2012/051600 WO2013005053A2 (en) | 2011-07-06 | 2012-07-06 | Progenitor cells of mesodermal lineage |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1120646T1 true CY1120646T1 (el) | 2019-12-11 |
Family
ID=46513785
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY181100736T CY1120646T1 (el) | 2011-07-06 | 2018-07-16 | Προγονικα κυτταρα μεσοδερμικης προελευσης |
Country Status (19)
Country | Link |
---|---|
US (3) | US10472609B2 (el) |
EP (1) | EP2729562B1 (el) |
JP (2) | JP6607675B2 (el) |
CN (2) | CN104508124B (el) |
AU (2) | AU2012279995C1 (el) |
CA (1) | CA2840307C (el) |
CY (1) | CY1120646T1 (el) |
DK (1) | DK2729562T3 (el) |
EA (1) | EA029577B1 (el) |
ES (1) | ES2675693T3 (el) |
HR (1) | HRP20181152T1 (el) |
HU (1) | HUE039236T2 (el) |
IL (2) | IL230071B (el) |
LT (1) | LT2729562T (el) |
MY (1) | MY185016A (el) |
PL (1) | PL2729562T3 (el) |
PT (1) | PT2729562T (el) |
SG (1) | SG10201605518XA (el) |
WO (1) | WO2013005053A2 (el) |
Families Citing this family (23)
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US20140335195A1 (en) | 2011-11-23 | 2014-11-13 | Cell Therapy Limited | Platelet lysate gel |
AU2014331523B2 (en) * | 2013-10-04 | 2020-10-01 | Cell Ideas Pty Ltd | Biomarkers for cell therapy |
GB201408712D0 (en) * | 2014-05-16 | 2014-07-02 | Univ Leuven Kath | Mesodermal progenitor cells |
GB201410504D0 (en) | 2014-06-12 | 2014-07-30 | Cell Therapy Ltd | Immuno-modulaltory progenitor (IMP) cell |
RU2017109584A (ru) * | 2014-08-29 | 2018-10-01 | Бектон, Дикинсон Энд Компани | Способы и композиции для получения оценки туберкулеза у субъекта |
WO2016131430A1 (en) * | 2015-02-20 | 2016-08-25 | Shih-Chieh Hung | Use of mesenchymal stem cells in treating osteoarthritis |
EP3091084A1 (en) * | 2015-05-08 | 2016-11-09 | Université Catholique De Louvain | Methods for assessing the purity of a mesenchymal stem cells preparation |
GB201513996D0 (en) * | 2015-08-07 | 2015-09-23 | Cell Therapy Ltd | Immuno-oncology mesodermal progenitor (IOMP) cell |
JP6830893B2 (ja) * | 2015-09-11 | 2021-02-17 | アステラス製薬株式会社 | 腎前駆細胞を製造する方法 |
GB201518263D0 (en) | 2015-10-15 | 2015-12-02 | Oxford Bioelectronics Ltd | Method |
CN105483206B (zh) * | 2016-01-06 | 2019-09-13 | 北京汉氏联合生物技术股份有限公司 | 一种用vcam-1检测msc促内皮细胞增殖能力的方法 |
KR20190039822A (ko) * | 2016-08-29 | 2019-04-15 | 해컨색 유니버시티 메디컬 센터 | 인간에서 혈소판-유사 세포를 함유하는 혈액의 혈소판 풍부 분획의 줄기세포능을 통해 성체 세포를 재프로그래밍하기 위한 조성물 및 방법 |
AU2017321300B2 (en) * | 2016-08-29 | 2022-11-17 | Hackensack University Medical Center | Compositions and methods for programming adult cells with platelet rich fraction of blood containing platelet-like cells |
JP7009977B2 (ja) * | 2017-12-25 | 2022-01-26 | 国立大学法人東海国立大学機構 | 被検体の血中vegf-aに関する測定値を用いた心疾患の重症度及び予後予測を行うための方法、装置及びコンピュータプログラム |
CN108715834B (zh) * | 2018-06-01 | 2021-09-14 | 天晴干细胞股份有限公司 | 一种富含cd41+、cd81+微囊的血小板裂解液制备方法 |
CN108715833B (zh) * | 2018-06-01 | 2021-09-14 | 天晴干细胞股份有限公司 | 一种负载血小板裂解液的微球制备方法 |
JP7416786B2 (ja) * | 2018-11-14 | 2024-01-17 | オンデルゾークス・エン オントビッケリングスフォンズ オーデ クラウス・フランデレン | 血小板放出物を調製するための方法 |
CN109329270A (zh) * | 2018-11-19 | 2019-02-15 | 成都清科生物科技有限公司 | 一种静脉回输用间充质干细胞保存液及其制备方法 |
GB201900554D0 (en) | 2019-01-15 | 2019-03-06 | Cell Therapy Ltd | Mesodermal killer (mk) cell |
AU2020209441A1 (en) * | 2019-01-15 | 2021-08-12 | Cell Therapy Limited | Mesodermal killer (MK) cell |
WO2020157660A1 (en) * | 2019-01-28 | 2020-08-06 | Mesoblast International Sárl | Method for treating or preventing gastrointestinal bleeding |
WO2020231968A1 (en) * | 2019-05-15 | 2020-11-19 | Stemcyte Inc. | High concentration cell packaging and shipping |
CN110237094B (zh) * | 2019-07-30 | 2023-10-03 | 天晴干细胞股份有限公司 | 一种底层血小板因子贴及sPL血小板因子凝胶贴膜的制备方法 |
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