PL1937721T3 - Przeciwciała anty-IL23 - Google Patents

Przeciwciała anty-IL23

Info

Publication number
PL1937721T3
PL1937721T3 PL06802075T PL06802075T PL1937721T3 PL 1937721 T3 PL1937721 T3 PL 1937721T3 PL 06802075 T PL06802075 T PL 06802075T PL 06802075 T PL06802075 T PL 06802075T PL 1937721 T3 PL1937721 T3 PL 1937721T3
Authority
PL
Poland
Prior art keywords
antibodies
antigen
binding portions
subunit
treatment
Prior art date
Application number
PL06802075T
Other languages
English (en)
Inventor
Catherine Brautigam Beidler
Stuart Willis Bright
Craig Duane Dickinson
Kristine Kay Kikly
David Matthew Marquis
Alain Philippe Vasserot
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of PL1937721T3 publication Critical patent/PL1937721T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
PL06802075T 2005-08-25 2006-08-23 Przeciwciała anty-IL23 PL1937721T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US71133605P 2005-08-25 2005-08-25
US77235506P 2006-02-10 2006-02-10
PCT/US2006/032752 WO2007024846A2 (en) 2005-08-25 2006-08-23 Anit-il-23 antibiodies
EP06802075A EP1937721B1 (en) 2005-08-25 2006-08-23 Anti-il-23 antibodies

Publications (1)

Publication Number Publication Date
PL1937721T3 true PL1937721T3 (pl) 2010-12-31

Family

ID=37616511

Family Applications (1)

Application Number Title Priority Date Filing Date
PL06802075T PL1937721T3 (pl) 2005-08-25 2006-08-23 Przeciwciała anty-IL23

Country Status (21)

Country Link
US (1) US7872102B2 (pl)
EP (1) EP1937721B1 (pl)
JP (1) JP5022367B2 (pl)
KR (1) KR101028200B1 (pl)
AT (1) ATE475672T1 (pl)
AU (1) AU2006283194B9 (pl)
BR (1) BRPI0615018A2 (pl)
CA (1) CA2619052A1 (pl)
CY (1) CY1110792T1 (pl)
DE (1) DE602006015830D1 (pl)
DK (1) DK1937721T3 (pl)
EA (1) EA013506B1 (pl)
ES (1) ES2347690T3 (pl)
HK (1) HK1119712A1 (pl)
IL (1) IL188312A0 (pl)
MX (1) MX2008002179A (pl)
NO (1) NO20081465L (pl)
PL (1) PL1937721T3 (pl)
PT (1) PT1937721E (pl)
SI (1) SI1937721T1 (pl)
WO (1) WO2007024846A2 (pl)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TR201902033T4 (tr) 2005-06-30 2019-03-21 Janssen Biotech Inc Anti-IL-23 antikorları, bileşimleri, yöntemleri ve kullanımları.
US7807160B2 (en) * 2005-08-31 2010-10-05 Schering Corporation Engineered anti-IL-23 antibodies
MX2008008621A (es) 2005-12-29 2008-11-27 Centocor Inc Anticuerpos anti-il-23 humanos, composiciones, metodos y usos.
US7790862B2 (en) 2006-06-13 2010-09-07 Zymogenetics, Inc. IL-17 and IL-23 antagonists and methods of using the same
US7910703B2 (en) 2006-03-10 2011-03-22 Zymogenetics, Inc. Antagonists to IL-17A, IL-17F, and IL-23P19 and methods of use
TWI426918B (zh) 2007-02-12 2014-02-21 Merck Sharp & Dohme Ｉｌ-２３拮抗劑於治療感染之用途
EP2064242A1 (en) * 2007-02-23 2009-06-03 Schering Corporation Engineered anti-il-23p19 antibodies
HUE042172T2 (hu) * 2007-02-23 2019-06-28 Merck Sharp & Dohme Genetikailag elõállított anti-il-23P19 antitestek
NZ579297A (en) 2007-02-28 2012-03-30 Schering Corp Combination therapy comprising an il-23 antagonist and a cytokine antagonist for treatment of immune disorders
PT2187964E (pt) * 2007-08-10 2015-01-14 Regeneron Pharma Anticorpos humanos de elevada afinidade para o factor de crescimento neural humano
US8309088B2 (en) 2007-08-10 2012-11-13 Regeneron Pharmaceuticals, Inc. Method of treating osteoarthritis with an antibody to NGF
AR068723A1 (es) * 2007-10-05 2009-12-02 Glaxo Group Ltd Proteina que se une a antigenos que se une a il-23 humana y sus usos
WO2009068630A1 (en) 2007-11-27 2009-06-04 Ablynx N.V. Immunoglobulin constructs
WO2009082624A2 (en) * 2007-12-10 2009-07-02 Zymogenetics, Inc. Antagonists of il-17a, il-17f, and il-23 and methods of using the same
WO2010027766A1 (en) 2008-08-27 2010-03-11 Schering Corporation Lyophilized formulatons of engineered anti-il-23p19 antibodies
CN102369285B (zh) * 2008-11-12 2014-06-18 默沙东公司 用于增强的抗-IGF1R表达的βGl-IgG内含子
US20110250644A1 (en) 2008-12-19 2011-10-13 Schering Corporation Feed supplement for mammalian cell culture and methods of use
JP2012522749A (ja) 2009-04-01 2012-09-27 グラクソ グループ リミテッド 抗ｉｌ−２３免疫グロブリン
EP2435480A1 (en) * 2009-05-27 2012-04-04 Ablynx N.V. Biparatopic protein constructs directed against il-23
US20120269765A1 (en) * 2009-07-24 2012-10-25 Garcia K Christopher Cytokine compositions and methods of use thereof
WO2011017294A1 (en) 2009-08-07 2011-02-10 Schering Corporation Human anti-rankl antibodies
JO3244B1 (ar) 2009-10-26 2018-03-08 Amgen Inc بروتينات ربط مستضادات il – 23 البشرية
WO2011079004A1 (en) 2009-12-23 2011-06-30 Schering Corporation Cell line 3m
US20110311527A1 (en) 2010-06-16 2011-12-22 Allergan, Inc. IL23p19 ANTIBODY INHIBITOR FOR TREATING OCULAR AND OTHER CONDITIONS
CA3017116A1 (en) 2010-11-04 2012-05-10 Boehringer Ingelheim International Gmbh Anti-il-23 antibodies
EP2583979B1 (en) 2011-10-19 2015-12-16 Effimune Methods to prepare antibodies directed against p19 subunit of human IL-23
ES2908474T3 (es) 2012-05-03 2022-04-29 Boehringer Ingelheim Int Anticuerpos anti-IL-23p19
US9708401B2 (en) 2012-05-22 2017-07-18 Bristol-Myers Squibb Company IL-17A/F cross-reactive monoclonal antibodies and methods of using the same
ES2729603T3 (es) 2012-06-27 2019-11-05 Merck Sharp & Dohme Anticuerpos IL-23 antihumanos cristalinos
UA117466C2 (uk) 2012-12-13 2018-08-10 Мерк Шарп Енд Доме Корп. СТАБІЛЬНИЙ СКЛАД У ВИГЛЯДІ РОЗЧИНУ АНТИТІЛА ДО IL-23p19
TWI636063B (zh) 2013-03-08 2018-09-21 美國禮來大藥廠 結合ｉｌ－２３之抗體
EA201591579A1 (ru) 2013-03-15 2016-01-29 Амген Инк. Способы лечения болезни крона при помощи анти-il-23 антитела
AU2014238148A1 (en) 2013-03-15 2015-10-08 Amgen Inc. Methods for treating psoriasis using an anti-IL-23 antibody
EP3708679A1 (en) 2014-07-24 2020-09-16 Boehringer Ingelheim International GmbH Biomarkers useful in the treatment of il-23a related diseases
TWI711629B (zh) 2014-09-03 2020-12-01 德商包林格因蓋爾漢國際股份有限公司 靶向IL-23A與TNF-α之化合物及其用途
AR102417A1 (es) 2014-11-05 2017-03-01 Lilly Co Eli Anticuerpos biespecíficos anti-tnf- / anti-il-23
EA201791734A1 (ru) 2015-02-04 2018-01-31 Бёрингер Ингельхайм Интернациональ Гмбх Способ лечения воспалительных заболеваний
MX2017013156A (es) 2015-04-14 2018-02-21 Boehringer Ingelheim Int Metodos para tratar enfermedades.
JP6909208B2 (ja) 2015-09-17 2021-07-28 アムジェン インコーポレイテッド Ｉｌ２３経路バイオマーカーを使用するｉｌ２３アンタゴニストに対する臨床応答の予測
TWI811716B (zh) * 2015-09-18 2023-08-11 德商百靈佳殷格翰國際股份有限公司 治療發炎性疾病之方法
CN108472367A (zh) 2015-12-22 2018-08-31 美国安进公司 作为对il23拮抗剂的临床应答的预测因子的ccl20
MX2018012410A (es) 2016-04-15 2019-02-21 Boehringer Ingelheim Int Metodos para tratar enfermedades inflamatorias.
EP3848390A1 (en) 2016-10-14 2021-07-14 Boehringer Ingelheim International GmbH Methods of treating diseases
US11845798B2 (en) 2017-05-02 2023-12-19 Merck Sharp & Dohme Llc Formulations of anti-LAG3 antibodies and co-formulations of anti-LAG3 antibodies and anti-PD-1 antibodies
JOP20190260A1 (ar) 2017-05-02 2019-10-31 Merck Sharp & Dohme صيغ ثابتة لأجسام مضادة لمستقبل الموت المبرمج 1 (pd-1) وطرق استخدامها
AR112341A1 (es) 2017-08-02 2019-10-16 Lilly Co Eli ANTICUERPOS BIESPECÍFICOS ANTI-TNF- / ANTI-IL-23 DE IgG
KR20210032441A (ko) 2018-07-13 2021-03-24 아스트라제네카 콜라보레이션 벤처스, 엘엘씨 브라지쿠맙을 이용한 궤양성 대장염의 치료
MA55149A (fr) 2018-11-20 2021-09-29 Janssen Biotech Inc Procédé sûr et efficace de traitement du psoriasis avec un anticorps spécifique anti-il-23
US11780911B2 (en) 2019-05-23 2023-10-10 Janssen Biotech, Inc. Method of treating inflammatory bowel disease with a combination therapy of antibodies to IL-23 and TNF alpha
CN112807428A (zh) * 2020-06-12 2021-05-18 江苏荃信生物医药有限公司 包含抗人白介素23单克隆抗体的药物组合物
CN114773466B (zh) * 2020-11-26 2023-08-29 江苏荃信生物医药股份有限公司 一种抗人白介素23及包含其的试剂盒及其检测方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3045480B2 (ja) * 1996-12-20 2000-05-29 大同メタル工業株式会社 ボーリング盤
US6060284A (en) * 1997-07-25 2000-05-09 Schering Corporation DNA encoding interleukin-B30
ATE474849T1 (de) * 1998-04-14 2010-08-15 Chugai Pharmaceutical Co Ltd Neues cytokinartiges protein
JP4505166B2 (ja) * 1999-09-09 2010-07-21 シェーリング コーポレイション 哺乳動物インターロイキン−１２ｐ４０およびインターロイキンｂ３０、その組成物、抗体、薬学的組成物における使用
WO2004071517A2 (en) * 2003-02-06 2004-08-26 Schering Corporation Uses of il-23 related reagents
DK1601694T3 (da) * 2003-03-10 2009-12-14 Schering Corp Anvendelser af IL23-antagonister, relaterede reagenser
BRPI0507794A (pt) * 2004-02-17 2007-07-17 Schering Corp métodos de modular a atividade de il-23, reagentes relacionados
MX2008008621A (es) * 2005-12-29 2008-11-27 Centocor Inc Anticuerpos anti-il-23 humanos, composiciones, metodos y usos.
JP5286287B2 (ja) * 2007-02-22 2013-09-11 ヒルズ・ペット・ニュートリシャン・インコーポレーテッド 骨発達を促進するための組成物及び方法

Also Published As

Publication number Publication date
US20090240036A1 (en) 2009-09-24
EP1937721A2 (en) 2008-07-02
DE602006015830D1 (de) 2010-09-09
ES2347690T3 (es) 2010-11-03
AU2006283194A1 (en) 2007-03-01
CA2619052A1 (en) 2007-03-01
BRPI0615018A2 (pt) 2011-04-26
ATE475672T1 (de) 2010-08-15
KR101028200B1 (ko) 2011-04-11
JP5022367B2 (ja) 2012-09-12
CY1110792T1 (el) 2015-06-10
SI1937721T1 (sl) 2010-11-30
AU2006283194B9 (en) 2011-02-03
EA013506B1 (ru) 2010-06-30
AU2006283194B8 (en) 2010-10-28
EA200800417A1 (ru) 2008-06-30
DK1937721T3 (da) 2010-10-18
WO2007024846A2 (en) 2007-03-01
AU2006283194B2 (en) 2010-10-21
NO20081465L (no) 2008-05-15
HK1119712A1 (en) 2009-03-13
PT1937721E (pt) 2010-09-17
IL188312A0 (en) 2008-04-13
KR20080031450A (ko) 2008-04-08
WO2007024846A3 (en) 2007-06-07
EP1937721B1 (en) 2010-07-28
JP2009506041A (ja) 2009-02-12
US7872102B2 (en) 2011-01-18
MX2008002179A (es) 2008-04-22

Similar Documents

Publication Publication Date Title
IL188312A0 (en) Anti-il-23 antibodies
TW200714290A (en) Anti-M-CSF antibody compositions having reduced levels of endotoxin
PH12021550337A1 (en) Anti-gdf15 antibodies, compositions and methods of use
EA200870050A1 (ru) Анти-il-17-антитела
MX2009001110A (es) Anticuerpos monoclonales anti-il-6 y usos de los mismos.
UA92505C2 (ru) Композиции на основе антитела против cd3
TW200740844A (en) Novel MAdCAM antibodies
MX2009006891A (es) Anticuerpos cd44.
TW200626171A (en) Fixed dosing of HER antibodies
WO2010017103A3 (en) Fully human anti-human nkg2d monoclonal antibodies
NZ592432A (en) Antibodies that specifically block the biological activity of a tumor antigen Kidney associated antigen 1 (KAAG1)
WO2014114651A9 (en) Tnf-alpha antigen-binding proteins
MX2010010387A (es) Anticuerpos especificos para el complejo de bcr y metodos para el uso de los mismos.
MX2009004532A (es) Composiciones y metodos para unir esfingosina-1-fosfato.
NO20084878L (no) Humanisert C-kit antistoff
MY156315A (en) Anti-vegf antibodies
EA200970874A1 (ru) Антитела против склеростина
WO2009026117A3 (en) Novel compounds
WO2013011076A3 (en) Tnf -alpha antigen- binding proteins with increased fcrn binding
WO2009112245A9 (en) Antibody against the csf-1 r
MX2009006471A (es) Anticuerpo anti especifico de linfopoyetina estromal timica de diseño.
MX2009008608A (es) Anticuerpos monoclonales anti-cxcl13.
MX2010005871A (es) Anticuerpos al antigeno de pcrv de pseudomonas aeruginosa.
WO2011004028A3 (en) Tlr3 binding agents
EA201101241A1 (ru) Лечение лейкозов и хронических миелопролиферативных болезней антителами к ерна3