SI2430022T1 - 1,2,3-triazolo(4,3-a)piridin derivati in njihova uporaba za zdravljenje ali prepreäśevanje nevroloĺ kih in psihiatriäśnih nepravilnosti - Google Patents

1,2,3-triazolo(4,3-a)piridin derivati in njihova uporaba za zdravljenje ali prepreäśevanje nevroloĺ kih in psihiatriäśnih nepravilnosti

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Publication number
SI2430022T1
SI2430022T1 SI201030449T SI201030449T SI2430022T1 SI 2430022 T1 SI2430022 T1 SI 2430022T1 SI 201030449 T SI201030449 T SI 201030449T SI 201030449 T SI201030449 T SI 201030449T SI 2430022 T1 SI2430022 T1 SI 2430022T1
Authority
SI
Slovenia
Prior art keywords
aćpyridine
neurological
prevention
derivatives
treatment
Prior art date
Application number
SI201030449T
Other languages
English (en)
Inventor
Jose Maria Cid-Nunez
Daniel Oehlrlch
Andres Avelino Trabanco-Suarez
Gary John Tresadern
Ramiro Juan Antonio Vega
Gregor James Macdonald
Original Assignee
Janssen Pharmaceuticals, Inc.
Addex Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceuticals, Inc., Addex Pharma Sa filed Critical Janssen Pharmaceuticals, Inc.
Publication of SI2430022T1 publication Critical patent/SI2430022T1/sl

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/438—The ring being spiro-condensed with carbocyclic or heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pyridine Compounds (AREA)
SI201030449T 2009-05-12 2010-05-11 1,2,3-triazolo(4,3-a)piridin derivati in njihova uporaba za zdravljenje ali prepreäśevanje nevroloĺ kih in psihiatriäśnih nepravilnosti SI2430022T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP09160059 2009-05-12
EP10721696.2A EP2430022B1 (en) 2009-05-12 2010-05-11 1,2,4-Triazolo[4,3-a]pyridine derivatives and their use for the treatment or prevention of neurological and psychiatric disorders
PCT/EP2010/002910 WO2010130424A1 (en) 2009-05-12 2010-05-11 1,2,3-triazolo [4,3-a] pyridine derivatives and their use for the treatment or prevention of neurological and psychiatric disorders

Publications (1)

Publication Number Publication Date
SI2430022T1 true SI2430022T1 (sl) 2014-04-30

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SI201030449T SI2430022T1 (sl) 2009-05-12 2010-05-11 1,2,3-triazolo(4,3-a)piridin derivati in njihova uporaba za zdravljenje ali prepreäśevanje nevroloĺ kih in psihiatriäśnih nepravilnosti

Country Status (32)

Country Link
US (4) US8937060B2 (sl)
EP (1) EP2430022B1 (sl)
JP (1) JP5634506B2 (sl)
KR (1) KR101753826B1 (sl)
CN (1) CN102439008B (sl)
AR (1) AR076861A1 (sl)
AU (1) AU2010246609B2 (sl)
BR (1) BRPI1012870B8 (sl)
CA (1) CA2760741C (sl)
CL (1) CL2011002838A1 (sl)
CY (1) CY1114718T1 (sl)
DK (1) DK2430022T3 (sl)
EA (1) EA020672B1 (sl)
ES (1) ES2440001T3 (sl)
HK (1) HK1169405A1 (sl)
HR (1) HRP20131122T1 (sl)
IL (1) IL215912A (sl)
JO (1) JO2907B1 (sl)
ME (1) ME01573B (sl)
MX (1) MX2011011964A (sl)
MY (1) MY161325A (sl)
NZ (1) NZ596078A (sl)
PL (1) PL2430022T3 (sl)
PT (1) PT2430022E (sl)
RS (1) RS53075B (sl)
SG (2) SG10201402250TA (sl)
SI (1) SI2430022T1 (sl)
SM (1) SMT201400003B (sl)
TW (1) TWI468406B (sl)
UA (1) UA108070C2 (sl)
WO (1) WO2010130424A1 (sl)
ZA (1) ZA201107834B (sl)

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BRPI0816767B8 (pt) 2007-09-14 2021-05-25 Addex Pharmaceuticals Sa composto 4-fenil-3,4,5,6-tetra-hidro-2h,1'h-[1,4']bipiridi¬nil-2'-onas 1',3'-dissubstituídas, composição farmacêutica e uso dos mesmos
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WO2010060589A1 (en) 2008-11-28 2010-06-03 Ortho-Mcneil-Janssen Pharmaceuticals, Inc. Indole and benzoxazine derivatives as modulators of metabotropic glutamate receptors
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JOP20150179B1 (ar) 2014-08-01 2021-08-17 Janssen Pharmaceutica Nv مركبات 6 ، 7 ثاني هيدرو بيرازولو [ 1، 5 الفا ] بيرازين – 4 (5 يد) – اون واستخدامها كمنظمات الوسترية سلبية لمستقبلات ملجور 2
CN107001373B (zh) 2014-08-01 2020-01-07 詹森药业有限公司 6,7-二氢吡唑并[1,5-a]吡嗪-4(5H)-酮化合物及其作为MGLUR2受体的负向别构调节剂的用途
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EP2430022B1 (en) 2013-11-20
US9226930B2 (en) 2016-01-05
US20120184525A1 (en) 2012-07-19
MX2011011964A (es) 2012-02-23
KR101753826B1 (ko) 2017-07-04
SG176021A1 (en) 2011-12-29
US9737533B2 (en) 2017-08-22
AR076861A1 (es) 2011-07-13
CL2011002838A1 (es) 2012-04-09
MY161325A (en) 2017-04-14
WO2010130424A9 (en) 2011-01-27
US20160067245A1 (en) 2016-03-10
PT2430022E (pt) 2013-12-26
ES2440001T3 (es) 2014-01-27
US8937060B2 (en) 2015-01-20
NZ596078A (en) 2013-06-28
UA108070C2 (uk) 2015-03-25
TW201100416A (en) 2011-01-01
AU2010246609A1 (en) 2011-11-17
BRPI1012870B8 (pt) 2021-05-25
US20150141403A1 (en) 2015-05-21

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