SG114992G - 3-aryloxy-3-substituted propanamines - Google Patents

3-aryloxy-3-substituted propanamines

Info

Publication number
SG114992G
SG114992G SG1149/92A SG114992A SG114992G SG 114992 G SG114992 G SG 114992G SG 1149/92 A SG1149/92 A SG 1149/92A SG 114992 A SG114992 A SG 114992A SG 114992 G SG114992 G SG 114992G
Authority
SG
Singapore
Prior art keywords
aryloxy
substituted propanamines
propanamines
substituted
Prior art date
Application number
SG1149/92A
Other languages
English (en)
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of SG114992G publication Critical patent/SG114992G/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/28Radicals substituted by nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, ***e
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36Radicals substituted by singly-bound nitrogen atoms
    • C07D213/38Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/20Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/28Halogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Furan Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
SG1149/92A 1986-12-22 1992-11-04 3-aryloxy-3-substituted propanamines SG114992G (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US94512286A 1986-12-22 1986-12-22

Publications (1)

Publication Number Publication Date
SG114992G true SG114992G (en) 1993-01-29

Family

ID=25482649

Family Applications (1)

Application Number Title Priority Date Filing Date
SG1149/92A SG114992G (en) 1986-12-22 1992-11-04 3-aryloxy-3-substituted propanamines

Country Status (27)

Country Link
EP (1) EP0273658B1 (el)
JP (1) JP2549681B2 (el)
KR (2) KR880007433A (el)
CN (1) CN1019113B (el)
AR (1) AR243868A1 (el)
AT (1) ATE57924T1 (el)
AU (1) AU591007B2 (el)
CA (1) CA1302421C (el)
CY (2) CY1682A (el)
DE (3) DE122005000002I1 (el)
DK (1) DK174599B1 (el)
EG (1) EG18230A (el)
ES (1) ES2019949B3 (el)
GR (1) GR3001207T3 (el)
HK (1) HK69693A (el)
HU (1) HU206309B (el)
IE (1) IE873449L (el)
IL (1) IL84863A (el)
LU (1) LU91131I2 (el)
MX (1) MX9845A (el)
NL (1) NL300171I2 (el)
NZ (1) NZ222980A (el)
PH (1) PH26556A (el)
PT (1) PT86389B (el)
SG (1) SG114992G (el)
SU (1) SU1598865A3 (el)
ZA (1) ZA879472B (el)

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US5362886A (en) * 1993-10-12 1994-11-08 Eli Lilly And Company Asymmetric synthesis
TW344661B (en) * 1993-11-24 1998-11-11 Lilly Co Eli Pharmaceutical composition for treatment of incontinence
GB0004152D0 (en) 2000-02-23 2000-04-12 Astrazeneca Uk Ltd Novel compounds
GB0004149D0 (en) 2000-02-23 2000-04-12 Astrazeneca Uk Ltd Novel compounds
GB0004153D0 (en) * 2000-02-23 2000-04-12 Astrazeneca Uk Ltd Novel use
GB0004151D0 (en) * 2000-02-23 2000-04-12 Astrazeneca Uk Ltd Novel use
SE0102640D0 (sv) 2001-07-31 2001-07-31 Astrazeneca Ab Novel compounds
EP1411912A1 (en) * 2001-07-31 2004-04-28 PHARMACIA & UPJOHN COMPANY Treatment of chronic pain with 3-aryloxy-3-phenylpropanamines
JP4625637B2 (ja) 2002-02-22 2011-02-02 シャイア エルエルシー 活性物質送達系及び活性物質を保護し投与する方法
US7659409B2 (en) 2002-03-19 2010-02-09 Mitsubishi Chemical Corporation 3-Hydroxy-3-(2-thienyl) propionamides and production method thereof, and production method of 3-amino-1-(2-thienyl)-1-propanols using the same
AU2003221028A1 (en) * 2002-03-19 2003-09-29 Mitsubishi Chemical Corporation 3-hydroxy-3-(2-thienyl)propionamide compound, process for producing the same, and process for producing 3-amino-1-(2-thienyl)-1-propanol compound therefrom
EP1506965A4 (en) * 2002-05-20 2010-11-03 Mitsubishi Rayon Co PROPANOLAMINE DERIVATIVES, PROCESS FOR THE PREPARATION OF 3-N-METHYLAMINO-1- (2-THIENYL) -1-PROPANOLS AND PROCESS FOR THE PREPARATION OF PROPANOLAMINE DERIVATIVES
DE10235206A1 (de) * 2002-08-01 2004-02-19 Basf Ag Verfahren zur Herstellung von (S)-3-Methylmino-1-(thien-2-yl)propan-1-ol
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DE102004004719A1 (de) 2004-01-29 2005-08-18 Basf Ag Verfahren zur Herstellung von enantiomerenreinen Aminoalkoholen
EA200601513A1 (ru) * 2004-02-19 2007-02-27 Лонца Аг Способ получения энантиомерно чистых 1-замещённых 3-аминоспиртов
DE102004022686A1 (de) 2004-05-05 2005-11-24 Basf Ag Verfahren zur Herstellung optisch aktiver Alkohole
GB0410470D0 (en) * 2004-05-11 2004-06-16 Cipla Ltd Pharmaceutical compound and polymorphs thereof
PE20060437A1 (es) 2004-06-18 2006-06-08 Novartis Ag COMPUESTOS AZA-BICICLONONANOS COMO LIGANDOS COLINERGICOS DE nAChR
GB0415746D0 (en) 2004-07-14 2004-08-18 Novartis Ag Organic compounds
JP2008510775A (ja) 2004-08-26 2008-04-10 ノイロサーチ アクティーゼルスカブ モノアミン神経伝達物質再取込み阻害剤としての新規な置換アリールオキシアルキルアミン及びそれらの使用
US20060194869A1 (en) * 2004-12-23 2006-08-31 Santiago Ini Process for preparing pharmaceutically acceptable salts of duloxetine and intermediates thereof
WO2006099433A1 (en) 2005-03-14 2006-09-21 Teva Pharmaceutical Industries Ltd. Pure duloxetine hydrochloride
GB0507298D0 (en) 2005-04-11 2005-05-18 Novartis Ag Organic compounds
JP5258561B2 (ja) 2005-07-15 2013-08-07 アルバニー モレキュラー リサーチ, インコーポレイテッド アリール置換およびヘテロアリール置換テトラヒドロベンズアゼピンならびにノルエピネフリン、ドーパミンおよびセロトニンの再取り込みを遮断するためのその使用
DE102005044736A1 (de) 2005-09-19 2007-03-22 Basf Ag Neue Dehydrogenasen, deren Derivate und ein Verfahren zur Herstellung von optisch aktiven Alkanolen
WO2007038253A2 (en) * 2005-09-22 2007-04-05 Teva Pharmaceutical Industries Ltd. Dnt-maleate and methods of preparation thereof
ITMI20051970A1 (it) 2005-10-18 2007-04-19 Solmag S P A Processo per la preparazione di eteri misti derivanti dall'inaftolo e intermedi di forme cristalline definite di + e - duloxetina
EP1957488B1 (en) * 2005-11-30 2009-09-09 F.Hoffmann-La Roche Ag 3-amino-2-arylpropyl azaindoles and uses thereof
WO2007067581A1 (en) 2005-12-05 2007-06-14 Teva Pharmaceutical Industries Ltd. 2-(n-methyl-propanamine)-3-(2-naphthol) thiophene, an impurity of duloxetine hydrochloride
GB0525672D0 (en) 2005-12-16 2006-01-25 Novartis Ag Organic compounds
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DE102005062662A1 (de) 2005-12-23 2007-06-28 Basf Ag Verfahren zur Herstellung optisch aktiver Alkohole
DE102005062661A1 (de) 2005-12-23 2007-08-16 Basf Ag Verfahren zur Herstellung von optisch aktivem (1S)-3-Chlor-(-thien-2-yl)-propan-1-ol
CZ299270B6 (cs) 2006-01-04 2008-06-04 Zentiva, A. S. Zpusob výroby hydrochloridu (S)-N-methyl-3-(1-naftyloxy)-3-(2-thienyl)propylaminu
US8362279B2 (en) 2006-01-06 2013-01-29 Msn Laboratories Limited Process for pure duloxetine hydrochloride
ATE552250T1 (de) 2006-12-22 2012-04-15 Synthon Bv Verfahren zur herstellung von duloxetin und verwandten verbindungen
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HU230480B1 (hu) * 2008-07-25 2016-07-28 Egis Gyógyszergyár Nyilvánosan Működő Részvénytársaság Eljárás N-metil-ariloxi-propánamin származékok előállítására
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CN106349211B (zh) * 2016-08-26 2020-10-16 江苏恩华药业股份有限公司 2-甲基-3-芳氧基-3-杂芳基丙胺类化合物及应用
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Also Published As

Publication number Publication date
KR880007433A (ko) 1988-08-27
IL84863A0 (en) 1988-06-30
CN1019113B (zh) 1992-11-18
DK174599B1 (da) 2003-07-14
HUT47561A (en) 1989-03-28
PT86389A (en) 1988-01-01
HU206309B (en) 1992-10-28
LU91131I2 (fr) 2005-03-29
JPS63185946A (ja) 1988-08-01
NZ222980A (en) 1989-11-28
GR3001207T3 (en) 1992-07-30
CY1682A (en) 1993-10-10
IE873449L (en) 1988-06-22
HK69693A (en) 1993-07-30
MX9845A (es) 1993-12-01
DK664887A (da) 1988-06-23
KR960003808B1 (ko) 1996-03-22
DE122005000002I2 (de) 2006-08-24
CY2005001I1 (el) 2009-11-04
DK664887D0 (da) 1987-12-17
DE122005000002I1 (de) 2005-05-12
SU1598865A3 (ru) 1990-10-07
AU591007B2 (en) 1989-11-23
NL300171I1 (nl) 2005-04-01
DE3765919D1 (de) 1990-12-06
IL84863A (en) 1992-03-29
ZA879472B (en) 1989-08-30
ATE57924T1 (de) 1990-11-15
PT86389B (pt) 1990-11-20
ES2019949B3 (es) 1991-07-16
PH26556A (en) 1992-08-19
EP0273658B1 (en) 1990-10-31
EP0273658A1 (en) 1988-07-06
EG18230A (en) 1992-10-30
CY2005001I2 (el) 2009-11-04
JP2549681B2 (ja) 1996-10-30
AU8266087A (en) 1988-06-23
AR243868A1 (es) 1993-09-30
CA1302421C (en) 1992-06-02
CN87108175A (zh) 1988-07-06
NL300171I2 (nl) 2005-06-01

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