NO170330C - Fremgangsmaate for fremstilling av vesentlig optisk rent monohydrat av s-(-)-propyl-2',6'-pipekoloksylididhydroklorid - Google Patents
Fremgangsmaate for fremstilling av vesentlig optisk rent monohydrat av s-(-)-propyl-2',6'-pipekoloksylididhydrokloridInfo
- Publication number
- NO170330C NO170330C NO864858A NO864858A NO170330C NO 170330 C NO170330 C NO 170330C NO 864858 A NO864858 A NO 864858A NO 864858 A NO864858 A NO 864858A NO 170330 C NO170330 C NO 170330C
- Authority
- NO
- Norway
- Prior art keywords
- pipecoloxylide
- hydrochloride
- propyl
- procedure
- preparation
- Prior art date
Links
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 title 1
- 150000004682 monohydrates Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE8600017A SE451840B (sv) | 1986-01-03 | 1986-01-03 | Optiskt rent monohydrat av s-(-)-1-propyl-2',6'-pipekoloxylididhydroklorid, sett att framstella denna och farmaceutiska beredningar for lokalbedovning |
Publications (4)
Publication Number | Publication Date |
---|---|
NO864858D0 NO864858D0 (no) | 1986-12-03 |
NO864858L NO864858L (no) | 1987-07-06 |
NO170330B NO170330B (no) | 1992-06-29 |
NO170330C true NO170330C (no) | 1992-10-07 |
Family
ID=20363001
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO864858A NO170330C (no) | 1986-01-03 | 1986-12-03 | Fremgangsmaate for fremstilling av vesentlig optisk rent monohydrat av s-(-)-propyl-2',6'-pipekoloksylididhydroklorid |
NO1997009C NO1997009I1 (no) | 1986-01-03 | 1997-07-31 | Ropivacain |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO1997009C NO1997009I1 (no) | 1986-01-03 | 1997-07-31 | Ropivacain |
Country Status (29)
Country | Link |
---|---|
US (1) | US4870086A (es) |
EP (1) | EP0239710B1 (es) |
JP (1) | JPH07598B2 (es) |
KR (1) | KR940008302B1 (es) |
AR (1) | AR242561A1 (es) |
AT (1) | ATE56956T1 (es) |
AU (1) | AU592392B2 (es) |
BG (1) | BG62066B2 (es) |
CA (1) | CA1276154C (es) |
CY (1) | CY1680A (es) |
DE (1) | DE3674582D1 (es) |
DK (1) | DK171378B1 (es) |
EG (1) | EG17867A (es) |
ES (1) | ES2036179T3 (es) |
FI (1) | FI83075C (es) |
GR (1) | GR3002516T3 (es) |
HK (1) | HK5493A (es) |
IE (1) | IE59061B1 (es) |
LU (1) | LU88843I2 (es) |
LV (1) | LV5765B4 (es) |
MY (1) | MY101132A (es) |
NL (1) | NL960005I2 (es) |
NO (2) | NO170330C (es) |
NZ (1) | NZ218615A (es) |
PH (1) | PH22924A (es) |
PT (1) | PT84041B (es) |
SE (1) | SE451840B (es) |
SG (1) | SG117292G (es) |
ZA (1) | ZA868600B (es) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2160736C2 (ru) * | 1990-06-07 | 2000-12-20 | Зенека Лимитед | Производные индола и их физиологически приемлемые соли и сольваты, способы их получения, лекарственное средство для лечения или профилактики клинических состояний, для которых показан прием агониста "5-нт1-подобного" рецептора, и способ его получения |
ES2082703B1 (es) * | 1993-11-04 | 1996-12-16 | Inst Investigacion Desarrollo | Nuevos derivados de ciclopropilo, procedimientos para su preparacion y aplicaciones. |
US5834490A (en) * | 1993-11-04 | 1998-11-10 | Instituto De Investigacion Y Desarrolo Quimico Biologico, S.A. | Cyclopropyl derivatives, preparation method there-of and applications |
US5786484A (en) * | 1994-09-23 | 1998-07-28 | Chiroscience Limited | Racemization and asymmetric transformation processes used in the manufacture of levobupivacaine and analogues thereof |
SE9501808D0 (sv) * | 1995-05-16 | 1995-05-16 | Astra Ab | New process |
US7799337B2 (en) | 1997-07-21 | 2010-09-21 | Levin Bruce H | Method for directed intranasal administration of a composition |
SE9800139D0 (sv) | 1998-01-21 | 1998-01-21 | Astra Ab | New use |
BRPI0104491B8 (pt) * | 2001-10-10 | 2021-05-25 | Cristalia Produtos Quim Farmaceuticos Ltda | n-(2,6-dimetilfenil)-1-propil-2-piperidinocarboxamida; processo de obtenção dos enantiômeros; mistura não racêmica dos anantiômeros e seu processo de obtenção e composição farmacêutica. |
US20060270708A1 (en) * | 2005-05-25 | 2006-11-30 | Navinta Llc | Novel process for preparation of isotonic aqueous injection of ropivacaine |
US7683175B2 (en) * | 2005-06-06 | 2010-03-23 | Navinta, Llc | Process of making optically pure L-pipecolic acid and process of making anesthetics and intermediates therefrom |
JP2009535327A (ja) * | 2006-04-25 | 2009-10-01 | ディシュマン・ファーマシューティカルズ・アンド・ケミカルズ・リミテッド | ロピバカイン塩酸塩無水物およびその調製 |
ES2383714T3 (es) * | 2008-01-15 | 2012-06-25 | Pharmathen S.A. | Proceso para preparar un compuesto (S)-1-alquil-2',6'-pipecoloxilidídico |
US8473062B2 (en) | 2008-05-01 | 2013-06-25 | Autonomic Technologies, Inc. | Method and device for the treatment of headache |
US8412336B2 (en) | 2008-12-29 | 2013-04-02 | Autonomic Technologies, Inc. | Integrated delivery and visualization tool for a neuromodulation system |
US9320908B2 (en) | 2009-01-15 | 2016-04-26 | Autonomic Technologies, Inc. | Approval per use implanted neurostimulator |
US8494641B2 (en) | 2009-04-22 | 2013-07-23 | Autonomic Technologies, Inc. | Implantable neurostimulator with integral hermetic electronic enclosure, circuit substrate, monolithic feed-through, lead assembly and anchoring mechanism |
CN102093284B (zh) * | 2010-12-29 | 2013-05-08 | 宜昌人福药业有限责任公司 | 富集哌啶-2-甲酰苯胺类旋光化合物的方法 |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2248018A (en) * | 1939-03-30 | 1941-07-01 | Winthrop Chem Co Inc | 4-aryl-piperidine-ketones and a process of preparing them |
GB775749A (en) * | 1955-04-06 | 1957-05-29 | Bofors Ab | Method of preparing amides of n-alkyl piperidine monocarboxylic acid and n-alkyl pyrrolidine -a-monocarboxylic acid |
GB775750A (en) * | 1955-04-28 | 1957-05-29 | Bofors Ab | Method of preparing amides of n-alkyl piperidine mono-carboxylic acid and n-alkyl pyrrolidine -a-monocarboxylic acid |
US2799679A (en) * | 1955-04-28 | 1957-07-16 | Bofors Ab | Process of preparing amides of heterocyclic carboxylic acids |
GB800565A (en) * | 1956-01-23 | 1958-08-27 | Bofors Ab | Method of producing n-alkyl-piperidine-ª‡-monocarboxylic acid amides and n-alkyl-pyrrolidine-ª‡-monocarboxylic acid amides |
GB824542A (en) * | 1957-05-15 | 1959-12-02 | Bofors Ab | Method of producing n-alkyl-piperidine-alpha-monocarboxylic acid amides |
GB869978A (en) * | 1958-03-13 | 1961-06-07 | Bofors Ab | Method of producing n-alkyl-and-cycloalkyl-piperidine carboxylic acid amides |
GB949729A (en) * | 1960-11-15 | 1964-02-19 | Bofors Ab | Substituted-piperidine carboxylic acid amide salts and their preparation |
SE341404B (es) * | 1967-05-18 | 1971-12-27 | Sterling Drug Inc | |
CH491915A (de) * | 1967-06-28 | 1970-06-15 | Geigy Ag J R | Verfahren zur Herstellung von neuen Piperidinderivaten |
US3879382A (en) * | 1971-08-27 | 1975-04-22 | Teijin Ltd | Process for the recovery of D- or L-{60 -amino-{68 -caprolactam hydrochloride of enhanced optical purity from mixtures of D- and L-{60 -amino-{68 -caprolactam hydrochloride |
SE7607114L (sv) * | 1976-06-22 | 1977-12-23 | Bofors Ab | Sett att framstella hydrokloriden av n-metylpiperidin-2-karbonsyra-2,6-xyllidid |
SE431092B (sv) * | 1979-07-10 | 1984-01-16 | Thuresson Af Ekenstam Bo | Terapeutiskt aktiva, substituerade piperidinkarboxianilider |
EP0151110B1 (en) * | 1983-08-01 | 1989-03-01 | Astra Läkemedel Aktiebolag | L-n-n-propylpipecolic acid-2,6-xylidide and method for preparing the same |
-
1986
- 1986-01-03 SE SE8600017A patent/SE451840B/sv not_active IP Right Cessation
- 1986-11-12 ZA ZA868600A patent/ZA868600B/xx unknown
- 1986-11-24 US US06/934,114 patent/US4870086A/en not_active Expired - Lifetime
- 1986-12-02 EG EG747/86A patent/EG17867A/xx active
- 1986-12-03 NO NO864858A patent/NO170330C/no not_active IP Right Cessation
- 1986-12-12 AU AU66449/86A patent/AU592392B2/en not_active Expired
- 1986-12-12 NZ NZ218615A patent/NZ218615A/xx unknown
- 1986-12-15 AT AT86850440T patent/ATE56956T1/de active
- 1986-12-15 PH PH34593A patent/PH22924A/en unknown
- 1986-12-15 ES ES198686850440T patent/ES2036179T3/es not_active Expired - Lifetime
- 1986-12-15 EP EP86850440A patent/EP0239710B1/en not_active Expired - Lifetime
- 1986-12-15 DE DE8686850440T patent/DE3674582D1/de not_active Expired - Lifetime
- 1986-12-26 JP JP61308983A patent/JPH07598B2/ja not_active Expired - Lifetime
- 1986-12-30 CA CA000526453A patent/CA1276154C/en not_active Expired - Lifetime
- 1986-12-30 MY MYPI86000260A patent/MY101132A/en unknown
- 1986-12-31 PT PT84041A patent/PT84041B/pt unknown
- 1986-12-31 KR KR1019860011720A patent/KR940008302B1/ko not_active IP Right Cessation
-
1987
- 1987-01-02 DK DK000287A patent/DK171378B1/da not_active IP Right Cessation
- 1987-01-02 FI FI870003A patent/FI83075C/fi not_active IP Right Cessation
- 1987-01-02 IE IE487A patent/IE59061B1/en not_active IP Right Cessation
-
1988
- 1988-12-17 AR AR88306211A patent/AR242561A1/es active
-
1990
- 1990-11-08 GR GR90400889T patent/GR3002516T3/el unknown
-
1992
- 1992-11-06 SG SG1172/92A patent/SG117292G/en unknown
-
1993
- 1993-01-21 HK HK54/93A patent/HK5493A/xx not_active IP Right Cessation
- 1993-10-10 CY CY1680A patent/CY1680A/xx unknown
-
1994
- 1994-02-18 BG BG98494A patent/BG62066B2/bg unknown
-
1996
- 1996-03-26 NL NL960005C patent/NL960005I2/nl unknown
- 1996-07-17 LV LV960261A patent/LV5765B4/xx unknown
- 1996-11-27 LU LU88843C patent/LU88843I2/fr unknown
-
1997
- 1997-07-31 NO NO1997009C patent/NO1997009I1/no unknown
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MK1K | Patent expired |