FI870003A - Optiskt ren foerening och foerfarande foer framstaellning daerav. - Google Patents

Optiskt ren foerening och foerfarande foer framstaellning daerav. Download PDF

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Publication number
FI870003A
FI870003A FI870003A FI870003A FI870003A FI 870003 A FI870003 A FI 870003A FI 870003 A FI870003 A FI 870003A FI 870003 A FI870003 A FI 870003A FI 870003 A FI870003 A FI 870003A
Authority
FI
Finland
Prior art keywords
foerening
optical ring
foerfarande foer
foer framstaellning
och foerfarande
Prior art date
Application number
FI870003A
Other languages
English (en)
Other versions
FI83075B (fi
FI870003A0 (fi
FI83075C (fi
Inventor
Rune Verner Sandberg
Original Assignee
Astra Laekemedel Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=20363001&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FI870003(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astra Laekemedel Ab filed Critical Astra Laekemedel Ab
Publication of FI870003A0 publication Critical patent/FI870003A0/fi
Publication of FI870003A publication Critical patent/FI870003A/fi
Publication of FI83075B publication Critical patent/FI83075B/fi
Application granted granted Critical
Publication of FI83075C publication Critical patent/FI83075C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
FI870003A 1986-01-03 1987-01-02 Foerfarande foer framstaellning av farmaceutiskt aktivt, optiskt rent monohydrat av (s)-(-)-1-propyl-2',6' -pipekoloxylididhydroklorid. FI83075C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE8600017 1986-01-03
SE8600017A SE451840B (sv) 1986-01-03 1986-01-03 Optiskt rent monohydrat av s-(-)-1-propyl-2',6'-pipekoloxylididhydroklorid, sett att framstella denna och farmaceutiska beredningar for lokalbedovning

Publications (4)

Publication Number Publication Date
FI870003A0 FI870003A0 (fi) 1987-01-02
FI870003A true FI870003A (fi) 1987-07-04
FI83075B FI83075B (fi) 1991-02-15
FI83075C FI83075C (fi) 1991-05-27

Family

ID=20363001

Family Applications (1)

Application Number Title Priority Date Filing Date
FI870003A FI83075C (fi) 1986-01-03 1987-01-02 Foerfarande foer framstaellning av farmaceutiskt aktivt, optiskt rent monohydrat av (s)-(-)-1-propyl-2',6' -pipekoloxylididhydroklorid.

Country Status (29)

Country Link
US (1) US4870086A (fi)
EP (1) EP0239710B1 (fi)
JP (1) JPH07598B2 (fi)
KR (1) KR940008302B1 (fi)
AR (1) AR242561A1 (fi)
AT (1) ATE56956T1 (fi)
AU (1) AU592392B2 (fi)
BG (1) BG62066B2 (fi)
CA (1) CA1276154C (fi)
CY (1) CY1680A (fi)
DE (1) DE3674582D1 (fi)
DK (1) DK171378B1 (fi)
EG (1) EG17867A (fi)
ES (1) ES2036179T3 (fi)
FI (1) FI83075C (fi)
GR (1) GR3002516T3 (fi)
HK (1) HK5493A (fi)
IE (1) IE59061B1 (fi)
LU (1) LU88843I2 (fi)
LV (1) LV5765B4 (fi)
MY (1) MY101132A (fi)
NL (1) NL960005I2 (fi)
NO (2) NO170330C (fi)
NZ (1) NZ218615A (fi)
PH (1) PH22924A (fi)
PT (1) PT84041B (fi)
SE (1) SE451840B (fi)
SG (1) SG117292G (fi)
ZA (1) ZA868600B (fi)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI21560B (sl) * 1990-06-07 2005-04-30 Astrazeneca Ab 3,5-disubstituirani indolni derivati kot "5-HT1-podobni" receptorski agonisti
ES2082703B1 (es) * 1993-11-04 1996-12-16 Inst Investigacion Desarrollo Nuevos derivados de ciclopropilo, procedimientos para su preparacion y aplicaciones.
US5834490A (en) * 1993-11-04 1998-11-10 Instituto De Investigacion Y Desarrolo Quimico Biologico, S.A. Cyclopropyl derivatives, preparation method there-of and applications
AU695479B2 (en) * 1994-09-23 1998-08-13 Darwin Discovery Limited Racemisation and asymmetric transformation processes used in the manufacture of levobupivacaine and analogues thereof
SE9501808D0 (sv) * 1995-05-16 1995-05-16 Astra Ab New process
US7799337B2 (en) 1997-07-21 2010-09-21 Levin Bruce H Method for directed intranasal administration of a composition
SE9800139D0 (sv) 1998-01-21 1998-01-21 Astra Ab New use
BRPI0104491B8 (pt) * 2001-10-10 2021-05-25 Cristalia Produtos Quim Farmaceuticos Ltda n-(2,6-dimetilfenil)-1-propil-2-piperidinocarboxamida; processo de obtenção dos enantiômeros; mistura não racêmica dos anantiômeros e seu processo de obtenção e composição farmacêutica.
US20060270708A1 (en) * 2005-05-25 2006-11-30 Navinta Llc Novel process for preparation of isotonic aqueous injection of ropivacaine
US7683175B2 (en) * 2005-06-06 2010-03-23 Navinta, Llc Process of making optically pure L-pipecolic acid and process of making anesthetics and intermediates therefrom
WO2007123405A1 (en) * 2006-04-25 2007-11-01 Dishman Pharmaceuticals And Chemicals Ltd. Ropivacaine hydrochloride anhydrate and the preparation thereof
DK2234974T3 (da) * 2008-01-15 2012-06-25 Pharmathen Sa Fremgangsmåde til fremstilling af (S)-1-alkyl-2',6'-pipecoloxylidid-forbindelse
US8473062B2 (en) 2008-05-01 2013-06-25 Autonomic Technologies, Inc. Method and device for the treatment of headache
US8412336B2 (en) 2008-12-29 2013-04-02 Autonomic Technologies, Inc. Integrated delivery and visualization tool for a neuromodulation system
US9320908B2 (en) 2009-01-15 2016-04-26 Autonomic Technologies, Inc. Approval per use implanted neurostimulator
US8494641B2 (en) 2009-04-22 2013-07-23 Autonomic Technologies, Inc. Implantable neurostimulator with integral hermetic electronic enclosure, circuit substrate, monolithic feed-through, lead assembly and anchoring mechanism
CN102093284B (zh) * 2010-12-29 2013-05-08 宜昌人福药业有限责任公司 富集哌啶-2-甲酰苯胺类旋光化合物的方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2248018A (en) * 1939-03-30 1941-07-01 Winthrop Chem Co Inc 4-aryl-piperidine-ketones and a process of preparing them
GB775749A (en) * 1955-04-06 1957-05-29 Bofors Ab Method of preparing amides of n-alkyl piperidine monocarboxylic acid and n-alkyl pyrrolidine -a-monocarboxylic acid
US2799679A (en) * 1955-04-28 1957-07-16 Bofors Ab Process of preparing amides of heterocyclic carboxylic acids
GB775750A (en) * 1955-04-28 1957-05-29 Bofors Ab Method of preparing amides of n-alkyl piperidine mono-carboxylic acid and n-alkyl pyrrolidine -a-monocarboxylic acid
GB800565A (en) * 1956-01-23 1958-08-27 Bofors Ab Method of producing n-alkyl-piperidine-ª‡-monocarboxylic acid amides and n-alkyl-pyrrolidine-ª‡-monocarboxylic acid amides
GB824542A (en) * 1957-05-15 1959-12-02 Bofors Ab Method of producing n-alkyl-piperidine-alpha-monocarboxylic acid amides
GB869978A (en) * 1958-03-13 1961-06-07 Bofors Ab Method of producing n-alkyl-and-cycloalkyl-piperidine carboxylic acid amides
GB949729A (en) * 1960-11-15 1964-02-19 Bofors Ab Substituted-piperidine carboxylic acid amide salts and their preparation
SE341404B (fi) * 1967-05-18 1971-12-27 Sterling Drug Inc
CH491915A (de) * 1967-06-28 1970-06-15 Geigy Ag J R Verfahren zur Herstellung von neuen Piperidinderivaten
US3879382A (en) * 1971-08-27 1975-04-22 Teijin Ltd Process for the recovery of D- or L-{60 -amino-{68 -caprolactam hydrochloride of enhanced optical purity from mixtures of D- and L-{60 -amino-{68 -caprolactam hydrochloride
SE7607114L (sv) * 1976-06-22 1977-12-23 Bofors Ab Sett att framstella hydrokloriden av n-metylpiperidin-2-karbonsyra-2,6-xyllidid
SE431092B (sv) * 1979-07-10 1984-01-16 Thuresson Af Ekenstam Bo Terapeutiskt aktiva, substituerade piperidinkarboxianilider
WO1985000599A1 (en) * 1983-08-01 1985-02-14 A/S Apothekernes Laboratorium For Specialpraeparat L-N-n-PROPYLPIPECOLIC ACID-2,6-XYLIDIDE AND METHOD FOR PREPARING THE SAME

Also Published As

Publication number Publication date
NO1997009I1 (no) 1997-08-18
MY101132A (en) 1991-07-31
AR242561A1 (es) 1993-04-30
IE870004L (en) 1987-07-03
ES2036179T3 (es) 1993-05-16
SE8600017L (sv) 1987-07-04
FI83075B (fi) 1991-02-15
EP0239710B1 (en) 1990-09-26
LV5765A4 (lv) 1996-12-20
NO170330B (no) 1992-06-29
KR940008302B1 (ko) 1994-09-12
ZA868600B (en) 1987-08-26
SE8600017D0 (sv) 1986-01-03
KR870007118A (ko) 1987-08-14
LU88843I2 (fr) 1997-03-14
JPS62158251A (ja) 1987-07-14
PH22924A (en) 1989-01-24
NZ218615A (en) 1989-07-27
BG62066B2 (bg) 1999-01-29
CA1276154C (en) 1990-11-13
ATE56956T1 (de) 1990-10-15
LV5765B4 (lv) 1997-06-20
AU592392B2 (en) 1990-01-11
SG117292G (en) 1993-01-29
GR3002516T3 (en) 1993-01-25
CY1680A (en) 1993-10-10
JPH07598B2 (ja) 1995-01-11
DK287A (da) 1987-07-04
PT84041B (pt) 1989-09-14
DK171378B1 (da) 1996-10-07
NO864858L (no) 1987-07-06
FI870003A0 (fi) 1987-01-02
DE3674582D1 (de) 1990-10-31
AU6644986A (en) 1987-07-09
SE451840B (sv) 1987-11-02
EP0239710A1 (en) 1987-10-07
NL960005I2 (nl) 1997-10-01
IE59061B1 (en) 1993-12-15
HK5493A (en) 1993-01-29
NL960005I1 (nl) 1996-09-02
US4870086A (en) 1989-09-26
DK287D0 (da) 1987-01-02
EG17867A (en) 1991-03-30
PT84041A (en) 1987-01-01
FI83075C (fi) 1991-05-27
NO170330C (no) 1992-10-07
NO864858D0 (no) 1986-12-03

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Legal Events

Date Code Title Description
ND Supplementary protection certificate (spc) granted
SPCG Supplementary protection certificate granted

Spc suppl protection certif: L85

Extension date: 20100915

FG Patent granted

Owner name: ASTRA LAEKEMEDEL AKTIEBOLAG

MA Patent expired