SE8600017D0 - New compound - Google Patents
New compoundInfo
- Publication number
- SE8600017D0 SE8600017D0 SE8600017A SE8600017A SE8600017D0 SE 8600017 D0 SE8600017 D0 SE 8600017D0 SE 8600017 A SE8600017 A SE 8600017A SE 8600017 A SE8600017 A SE 8600017A SE 8600017 D0 SE8600017 D0 SE 8600017D0
- Authority
- SE
- Sweden
- Prior art keywords
- new compound
- chem
- propyl
- preparation
- structural formula
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 1
- DKAGJZJALZXOOV-UHFFFAOYSA-N hydrate;hydrochloride Chemical compound O.Cl DKAGJZJALZXOOV-UHFFFAOYSA-N 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 238000002690 local anesthesia Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Priority Applications (30)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE8600017A SE451840B (sv) | 1986-01-03 | 1986-01-03 | Optiskt rent monohydrat av s-(-)-1-propyl-2',6'-pipekoloxylididhydroklorid, sett att framstella denna och farmaceutiska beredningar for lokalbedovning |
ZA868600A ZA868600B (en) | 1986-01-03 | 1986-11-12 | An optically pure compound and a process for its preparation |
US06/934,114 US4870086A (en) | 1986-01-03 | 1986-11-24 | Optically pure compound and a process for its preparation |
EG747/86A EG17867A (en) | 1986-01-03 | 1986-12-02 | Process for the preparation of optically pure compound |
NO864858A NO170330C (no) | 1986-01-03 | 1986-12-03 | Fremgangsmaate for fremstilling av vesentlig optisk rent monohydrat av s-(-)-propyl-2',6'-pipekoloksylididhydroklorid |
AU66449/86A AU592392B2 (en) | 1986-01-03 | 1986-12-12 | S-(-)-1-propyl-2', 6' pipecoloxylidide hydrochloride monohydrate and a method for its preparation |
NZ218615A NZ218615A (en) | 1986-01-03 | 1986-12-12 | S-(-)-1-propyl-2',6'-pipecoloxylidide hydrochloride monohydrate and local anesthesia compositions |
EP86850440A EP0239710B1 (en) | 1986-01-03 | 1986-12-15 | (s)-(-)-1-propyl-2',6'-pipecoloxylidide hydrochloride monohydrate, process for its preparation and pharmaceutical preparation containing it |
ES198686850440T ES2036179T3 (es) | 1986-01-03 | 1986-12-15 | Procedimiento para preparar monohidrato de hidrocloruro de (s)-(-)-1-propil-2',6'-pipecoloxilidida. |
DE8686850440T DE3674582D1 (de) | 1986-01-03 | 1986-12-15 | (s)-(-)-1-propyl-2',6'-pipecoloxylidid-hydrochloridmonohydrat, verfahren zu seiner herstellung und es enthaltendes pharmazeutisches praeparat. |
PH34593A PH22924A (en) | 1986-01-03 | 1986-12-15 | Optically pure monohydrate of s-(-)-1-propyl-2',6' pipecoloxylidide hydrochloride and a process for its preparation |
AT86850440T ATE56956T1 (de) | 1986-01-03 | 1986-12-15 | (s)-(-)-1-propyl-2',6'-pipecoloxylididhydrochloridmonohydrat, verfahren zu seiner herstellung und es enthaltendes pharmazeutisches praeparat. |
JP61308983A JPH07598B2 (ja) | 1986-01-03 | 1986-12-26 | 光学的に純粋な化合物およびその製造方法 |
MYPI86000260A MY101132A (en) | 1986-01-03 | 1986-12-30 | An optically pure pipecoloxylidide hydrochloride and a process for its preparation |
CA000526453A CA1276154C (en) | 1986-01-03 | 1986-12-30 | Optically pure s-(-)-1-propyl-2,6-pipecoloxylidide hydrochloride monohydrate and a process for its preparation |
PT84041A PT84041B (pt) | 1986-01-03 | 1986-12-31 | Processo para a preparacao do cloridrato de s-(-)-1-propil-2',6'-pipecoloxilidido monohidratado opticamente puro e de composicoes farmaceuticas que o contem |
KR1019860011720A KR940008302B1 (ko) | 1986-01-03 | 1986-12-31 | 광학적으로 순수한 s-(-)-1-프로필-2',6'-피페콜옥실리디드 염산염의 제조방법 |
FI870003A FI83075C (sv) | 1986-01-03 | 1987-01-02 | Förfarande för framställning av farmaceutiskt aktivt, optiskt rent mon ohydrat av (S)-(-)-1-propyl-2',6'-pipekoloxylididhydroklorid |
DK000287A DK171378B1 (da) | 1986-01-03 | 1987-01-02 | S-(-)-1-propyl-2',6'-pipecoloxylididhydrochlorid-monohydrat, fremgangsmåde til fremstilling af samme og farmaceutiske præparater indeholdende forbindelsen |
IE487A IE59061B1 (en) | 1986-01-03 | 1987-01-02 | An optically pure compound and a process for its preparation |
AR88306211A AR242561A1 (es) | 1986-01-03 | 1988-12-17 | Procedimiento para la preparacion de clorhidrato de s-(-)-1-propil-2',6'-pipecoloxilidida opticamente sustancialmente puro y procedimiento |
GR90400889T GR3002516T3 (en) | 1986-01-03 | 1990-11-08 | (s)-(-)-1-propyl-2',6'-pipecoloxylidide hydrochloride monohydrate, process for its preparation and pharmaceutical preparation containing it |
SG1172/92A SG117292G (en) | 1986-01-03 | 1992-11-06 | (s)-(-)-1-propyl-2',6'-pipecoloxylidide hydrochloride monohydrate,process for its preparation and pharmaceutical preparation containing it |
HK54/93A HK5493A (en) | 1986-01-03 | 1993-01-21 | (s)-(-)-1-propyl-2',6'-pipecoloxylidide hydrochloride monohydrate,process for its preparation and pharmaceutical preparation containing it |
CY1680A CY1680A (en) | 1986-01-03 | 1993-10-10 | (s)-(-)-1-propyl-2',6'-pipecoloxylidide hydrochloride monohydrate,process for its preparation and pharmaceutical preparation containing it |
BG98494A BG62066B2 (bg) | 1986-01-03 | 1994-02-18 | (s)-(-)-1-пропил-2',6'-пипеколоксилидидов хидрохлорид монохидрат, метод за получаването му и фармацевтичен препарат, който го съдържа |
NL960005C NL960005I2 (nl) | 1986-01-03 | 1996-03-26 | Optisch zuivere verbinding, en werkwijze voor de bereiding daarvan. |
LV960261A LV5765B4 (lv) | 1986-01-03 | 1996-07-17 | (S)-(-)-1-propil-2',6'-pipekoloksilidida hidrohlorida monohidrats ta iegusanas metode un to satuross farmaceitisks preparats |
LU88843C LU88843I2 (fr) | 1986-01-03 | 1996-11-27 | Ropivacaine et ses dérivés pharmaceutiquement acceptables (Naropine R) |
NO1997009C NO1997009I1 (no) | 1986-01-03 | 1997-07-31 | Ropivacain |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE8600017A SE451840B (sv) | 1986-01-03 | 1986-01-03 | Optiskt rent monohydrat av s-(-)-1-propyl-2',6'-pipekoloxylididhydroklorid, sett att framstella denna och farmaceutiska beredningar for lokalbedovning |
Publications (3)
Publication Number | Publication Date |
---|---|
SE8600017D0 true SE8600017D0 (sv) | 1986-01-03 |
SE8600017L SE8600017L (sv) | 1987-07-04 |
SE451840B SE451840B (sv) | 1987-11-02 |
Family
ID=20363001
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE8600017A SE451840B (sv) | 1986-01-03 | 1986-01-03 | Optiskt rent monohydrat av s-(-)-1-propyl-2',6'-pipekoloxylididhydroklorid, sett att framstella denna och farmaceutiska beredningar for lokalbedovning |
Country Status (29)
Country | Link |
---|---|
US (1) | US4870086A (sv) |
EP (1) | EP0239710B1 (sv) |
JP (1) | JPH07598B2 (sv) |
KR (1) | KR940008302B1 (sv) |
AR (1) | AR242561A1 (sv) |
AT (1) | ATE56956T1 (sv) |
AU (1) | AU592392B2 (sv) |
BG (1) | BG62066B2 (sv) |
CA (1) | CA1276154C (sv) |
CY (1) | CY1680A (sv) |
DE (1) | DE3674582D1 (sv) |
DK (1) | DK171378B1 (sv) |
EG (1) | EG17867A (sv) |
ES (1) | ES2036179T3 (sv) |
FI (1) | FI83075C (sv) |
GR (1) | GR3002516T3 (sv) |
HK (1) | HK5493A (sv) |
IE (1) | IE59061B1 (sv) |
LU (1) | LU88843I2 (sv) |
LV (1) | LV5765B4 (sv) |
MY (1) | MY101132A (sv) |
NL (1) | NL960005I2 (sv) |
NO (2) | NO170330C (sv) |
NZ (1) | NZ218615A (sv) |
PH (1) | PH22924A (sv) |
PT (1) | PT84041B (sv) |
SE (1) | SE451840B (sv) |
SG (1) | SG117292G (sv) |
ZA (1) | ZA868600B (sv) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SI21560B (sl) * | 1990-06-07 | 2005-04-30 | Astrazeneca Ab | 3,5-disubstituirani indolni derivati kot "5-HT1-podobni" receptorski agonisti |
ES2082703B1 (es) * | 1993-11-04 | 1996-12-16 | Inst Investigacion Desarrollo | Nuevos derivados de ciclopropilo, procedimientos para su preparacion y aplicaciones. |
US5834490A (en) * | 1993-11-04 | 1998-11-10 | Instituto De Investigacion Y Desarrolo Quimico Biologico, S.A. | Cyclopropyl derivatives, preparation method there-of and applications |
AU695479B2 (en) * | 1994-09-23 | 1998-08-13 | Darwin Discovery Limited | Racemisation and asymmetric transformation processes used in the manufacture of levobupivacaine and analogues thereof |
SE9501808D0 (sv) * | 1995-05-16 | 1995-05-16 | Astra Ab | New process |
US7799337B2 (en) | 1997-07-21 | 2010-09-21 | Levin Bruce H | Method for directed intranasal administration of a composition |
SE9800139D0 (sv) | 1998-01-21 | 1998-01-21 | Astra Ab | New use |
BRPI0104491B8 (pt) * | 2001-10-10 | 2021-05-25 | Cristalia Produtos Quim Farmaceuticos Ltda | n-(2,6-dimetilfenil)-1-propil-2-piperidinocarboxamida; processo de obtenção dos enantiômeros; mistura não racêmica dos anantiômeros e seu processo de obtenção e composição farmacêutica. |
US20060270708A1 (en) * | 2005-05-25 | 2006-11-30 | Navinta Llc | Novel process for preparation of isotonic aqueous injection of ropivacaine |
US7683175B2 (en) * | 2005-06-06 | 2010-03-23 | Navinta, Llc | Process of making optically pure L-pipecolic acid and process of making anesthetics and intermediates therefrom |
WO2007123405A1 (en) * | 2006-04-25 | 2007-11-01 | Dishman Pharmaceuticals And Chemicals Ltd. | Ropivacaine hydrochloride anhydrate and the preparation thereof |
DK2234974T3 (da) * | 2008-01-15 | 2012-06-25 | Pharmathen Sa | Fremgangsmåde til fremstilling af (S)-1-alkyl-2',6'-pipecoloxylidid-forbindelse |
US8473062B2 (en) | 2008-05-01 | 2013-06-25 | Autonomic Technologies, Inc. | Method and device for the treatment of headache |
US8412336B2 (en) | 2008-12-29 | 2013-04-02 | Autonomic Technologies, Inc. | Integrated delivery and visualization tool for a neuromodulation system |
US9320908B2 (en) | 2009-01-15 | 2016-04-26 | Autonomic Technologies, Inc. | Approval per use implanted neurostimulator |
US8494641B2 (en) | 2009-04-22 | 2013-07-23 | Autonomic Technologies, Inc. | Implantable neurostimulator with integral hermetic electronic enclosure, circuit substrate, monolithic feed-through, lead assembly and anchoring mechanism |
CN102093284B (zh) * | 2010-12-29 | 2013-05-08 | 宜昌人福药业有限责任公司 | 富集哌啶-2-甲酰苯胺类旋光化合物的方法 |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2248018A (en) * | 1939-03-30 | 1941-07-01 | Winthrop Chem Co Inc | 4-aryl-piperidine-ketones and a process of preparing them |
GB775749A (en) * | 1955-04-06 | 1957-05-29 | Bofors Ab | Method of preparing amides of n-alkyl piperidine monocarboxylic acid and n-alkyl pyrrolidine -a-monocarboxylic acid |
US2799679A (en) * | 1955-04-28 | 1957-07-16 | Bofors Ab | Process of preparing amides of heterocyclic carboxylic acids |
GB775750A (en) * | 1955-04-28 | 1957-05-29 | Bofors Ab | Method of preparing amides of n-alkyl piperidine mono-carboxylic acid and n-alkyl pyrrolidine -a-monocarboxylic acid |
GB800565A (en) * | 1956-01-23 | 1958-08-27 | Bofors Ab | Method of producing n-alkyl-piperidine-ª‡-monocarboxylic acid amides and n-alkyl-pyrrolidine-ª‡-monocarboxylic acid amides |
GB824542A (en) * | 1957-05-15 | 1959-12-02 | Bofors Ab | Method of producing n-alkyl-piperidine-alpha-monocarboxylic acid amides |
GB869978A (en) * | 1958-03-13 | 1961-06-07 | Bofors Ab | Method of producing n-alkyl-and-cycloalkyl-piperidine carboxylic acid amides |
GB949729A (en) * | 1960-11-15 | 1964-02-19 | Bofors Ab | Substituted-piperidine carboxylic acid amide salts and their preparation |
SE341404B (sv) * | 1967-05-18 | 1971-12-27 | Sterling Drug Inc | |
CH491915A (de) * | 1967-06-28 | 1970-06-15 | Geigy Ag J R | Verfahren zur Herstellung von neuen Piperidinderivaten |
US3879382A (en) * | 1971-08-27 | 1975-04-22 | Teijin Ltd | Process for the recovery of D- or L-{60 -amino-{68 -caprolactam hydrochloride of enhanced optical purity from mixtures of D- and L-{60 -amino-{68 -caprolactam hydrochloride |
SE7607114L (sv) * | 1976-06-22 | 1977-12-23 | Bofors Ab | Sett att framstella hydrokloriden av n-metylpiperidin-2-karbonsyra-2,6-xyllidid |
SE431092B (sv) * | 1979-07-10 | 1984-01-16 | Thuresson Af Ekenstam Bo | Terapeutiskt aktiva, substituerade piperidinkarboxianilider |
WO1985000599A1 (en) * | 1983-08-01 | 1985-02-14 | A/S Apothekernes Laboratorium For Specialpraeparat | L-N-n-PROPYLPIPECOLIC ACID-2,6-XYLIDIDE AND METHOD FOR PREPARING THE SAME |
-
1986
- 1986-01-03 SE SE8600017A patent/SE451840B/sv not_active IP Right Cessation
- 1986-11-12 ZA ZA868600A patent/ZA868600B/xx unknown
- 1986-11-24 US US06/934,114 patent/US4870086A/en not_active Expired - Lifetime
- 1986-12-02 EG EG747/86A patent/EG17867A/xx active
- 1986-12-03 NO NO864858A patent/NO170330C/no not_active IP Right Cessation
- 1986-12-12 AU AU66449/86A patent/AU592392B2/en not_active Expired
- 1986-12-12 NZ NZ218615A patent/NZ218615A/xx unknown
- 1986-12-15 DE DE8686850440T patent/DE3674582D1/de not_active Expired - Lifetime
- 1986-12-15 PH PH34593A patent/PH22924A/en unknown
- 1986-12-15 AT AT86850440T patent/ATE56956T1/de active
- 1986-12-15 EP EP86850440A patent/EP0239710B1/en not_active Expired - Lifetime
- 1986-12-15 ES ES198686850440T patent/ES2036179T3/es not_active Expired - Lifetime
- 1986-12-26 JP JP61308983A patent/JPH07598B2/ja not_active Expired - Lifetime
- 1986-12-30 MY MYPI86000260A patent/MY101132A/en unknown
- 1986-12-30 CA CA000526453A patent/CA1276154C/en not_active Expired - Lifetime
- 1986-12-31 PT PT84041A patent/PT84041B/pt unknown
- 1986-12-31 KR KR1019860011720A patent/KR940008302B1/ko not_active IP Right Cessation
-
1987
- 1987-01-02 IE IE487A patent/IE59061B1/en not_active IP Right Cessation
- 1987-01-02 DK DK000287A patent/DK171378B1/da not_active IP Right Cessation
- 1987-01-02 FI FI870003A patent/FI83075C/sv not_active IP Right Cessation
-
1988
- 1988-12-17 AR AR88306211A patent/AR242561A1/es active
-
1990
- 1990-11-08 GR GR90400889T patent/GR3002516T3/el unknown
-
1992
- 1992-11-06 SG SG1172/92A patent/SG117292G/en unknown
-
1993
- 1993-01-21 HK HK54/93A patent/HK5493A/xx not_active IP Right Cessation
- 1993-10-10 CY CY1680A patent/CY1680A/xx unknown
-
1994
- 1994-02-18 BG BG98494A patent/BG62066B2/bg unknown
-
1996
- 1996-03-26 NL NL960005C patent/NL960005I2/nl unknown
- 1996-07-17 LV LV960261A patent/LV5765B4/xx unknown
- 1996-11-27 LU LU88843C patent/LU88843I2/fr unknown
-
1997
- 1997-07-31 NO NO1997009C patent/NO1997009I1/no unknown
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Legal Events
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NAL | Patent in force |
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