NL194717B - Blokkeermiddelen van EDRF-effect of -vorming ter behandeling van shock. - Google Patents

Blokkeermiddelen van EDRF-effect of -vorming ter behandeling van shock.

Info

Publication number
NL194717B
NL194717B NL9002720A NL9002720A NL194717B NL 194717 B NL194717 B NL 194717B NL 9002720 A NL9002720 A NL 9002720A NL 9002720 A NL9002720 A NL 9002720A NL 194717 B NL194717 B NL 194717B
Authority
NL
Netherlands
Prior art keywords
edrf
blockers
formation
effect
treat shock
Prior art date
Application number
NL9002720A
Other languages
English (en)
Other versions
NL194717C (nl
NL9002720A (nl
Original Assignee
Sociutu De Conseils De Rech S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sociutu De Conseils De Rech S filed Critical Sociutu De Conseils De Rech S
Publication of NL9002720A publication Critical patent/NL9002720A/nl
Publication of NL194717B publication Critical patent/NL194717B/nl
Application granted granted Critical
Publication of NL194717C publication Critical patent/NL194717C/nl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/02Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Toxicology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polyurethanes Or Polyureas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NL9002720A 1989-12-22 1990-12-11 Blokkeermiddelen van EDRF-effect of -vorming ter behandeling van shock. NL194717C (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8929076 1989-12-22
GB898929076A GB8929076D0 (en) 1989-12-22 1989-12-22 Treatment of shock by blocking agents of edrf effect or formation

Publications (3)

Publication Number Publication Date
NL9002720A NL9002720A (nl) 1991-07-16
NL194717B true NL194717B (nl) 2002-09-02
NL194717C NL194717C (nl) 2003-01-07

Family

ID=10668428

Family Applications (1)

Application Number Title Priority Date Filing Date
NL9002720A NL194717C (nl) 1989-12-22 1990-12-11 Blokkeermiddelen van EDRF-effect of -vorming ter behandeling van shock.

Country Status (21)

Country Link
US (1) US5081148A (nl)
JP (1) JP2706578B2 (nl)
KR (1) KR950005866B1 (nl)
AT (1) AT403122B (nl)
AU (1) AU629777B2 (nl)
BE (1) BE1005531A5 (nl)
CA (1) CA2032904C (nl)
CH (1) CH681692A5 (nl)
DE (1) DE4041283C2 (nl)
DK (1) DK176168B1 (nl)
FR (1) FR2656220B1 (nl)
GB (2) GB8929076D0 (nl)
HK (1) HK134693A (nl)
IE (1) IE64403B1 (nl)
IT (1) IT1246511B (nl)
LU (1) LU87867A1 (nl)
MY (1) MY105328A (nl)
NL (1) NL194717C (nl)
OA (1) OA09337A (nl)
SE (1) SE504922C2 (nl)
ZA (1) ZA9010004B (nl)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE468881B (sv) * 1991-01-09 1993-04-05 Kabi Pharmacia Ab Anvaendning av vissa foereningar foer framstaellning av laekemedel foer behandling av endotoxininducerade effekter samt saett att avlaegsna endotoxiner ur diverse loesningar
GB9127376D0 (en) * 1991-12-24 1992-02-19 Wellcome Found Amidino derivatives
GB9200114D0 (en) * 1992-01-04 1992-02-26 Scras Dual inhibitors of no synthase and cyclooxygenase
US5385940A (en) * 1992-11-05 1995-01-31 The General Hospital Corporation Treatment of stroke with nitric-oxide releasing compounds
US5585402A (en) * 1992-12-23 1996-12-17 Glaxo Wellcome Inc. Nitric oxide synthase inhibitors
US5436270A (en) * 1993-04-07 1995-07-25 National Science Council Method for protecting against endotoxin-induced shock
GB9312204D0 (en) * 1993-06-14 1993-07-28 Zeneca Ltd Therapeutic composition
GB9312761D0 (en) * 1993-06-21 1993-08-04 Wellcome Found Amino acid derivatives
US6297276B1 (en) 1993-10-04 2001-10-02 Glaxosmithkline Substituted urea and isothiourea derivatives as no synthase inhibitors
US6090846A (en) * 1994-06-01 2000-07-18 Glaxo Wellcome Inc. Substituted urea and isothiourea derivatives as no synthase inhibitors
US6225305B1 (en) 1993-10-04 2001-05-01 Glaxo Wellcome Inc. Substituted urea and isothiorea derivatives as no synthase inhibitors
EP0724435B1 (en) * 1993-10-21 2002-08-14 G.D. Searle & Co. Amidino derivatives useful as nitric oxide synthase inhibitors
ATE177078T1 (de) * 1993-10-21 1999-03-15 Searle & Co Amidino-derivate als no-synthetase inhibitoren
GB9404400D0 (en) * 1994-03-07 1994-04-20 Wood Pauline J Potentiation of bioreductive agents
ES2151055T3 (es) * 1994-03-10 2000-12-16 Searle & Co Derivados de l-n6-(1-iminoetil)lisina utiles como inhibidores de oxido nitrico sintasa.
US5684008A (en) 1994-11-09 1997-11-04 G. D. Searle & Co. Aminotetrazole derivatives useful as nitric oxide synthase inhibitors
FR2727111B1 (fr) * 1994-11-21 1997-01-17 Hoechst Lab Nouveaux analogues soufres d'aminoacides, leur procede de preparation et leurs applications comme medicaments
JPH10510540A (ja) * 1994-12-12 1998-10-13 オメロス メディカル システムズ,インコーポレーテッド 灌注用溶液並びに疼痛、炎症及びけいれんの抑制法
RU2180852C2 (ru) * 1994-12-12 2002-03-27 Омерос Медикл Системс, Инк. Ингибирующий раствор и способ подавления боли, воспаления или спазма
KR100517210B1 (ko) * 1994-12-12 2006-06-07 오메로스 코포레이션 통증,염증및경련억제용관주용액
FR2730930B1 (fr) 1995-02-27 1997-04-04 Oreal Utilisation d'inhibiteurs de no-synthase pour diminuer l'effet irritant cutane de produits utilises dans le domaine cosmetique ou pharmaceutique
GB9504350D0 (en) * 1995-03-04 1995-04-26 Sod Conseils Rech Applic Arginine derivatives
ATE246678T1 (de) * 1995-04-20 2003-08-15 Searle & Co Zyclische amidino mittel als stickstoffoxid- synthase inhibitoren
US5830917A (en) * 1995-09-11 1998-11-03 G. D. Searle & Co. L-N6 -(1-iminoethyl) lysine derivatives useful as nitric oxide synthase inhibitors
US5981511A (en) * 1996-03-06 1999-11-09 G.D. Searle & Co. Hydroxyamidino derivatives useful as nitric oxide synthase inhibitors
US5945408A (en) * 1996-03-06 1999-08-31 G.D. Searle & Co. Hydroxyanidino derivatives useful as nitric oxide synthase inhibitors
US6369272B1 (en) 1997-01-13 2002-04-09 Glaxosmithkline Nitric oxide synthase inhibitors
US6620848B2 (en) 1997-01-13 2003-09-16 Smithkline Beecham Corporation Nitric oxide synthase inhibitors
US5981556A (en) * 1997-07-22 1999-11-09 G.D. Searle & Co. 1,3-diazolino and 1,3-diazolidino heterocycles as useful nitric oxide synthase inhibitors
GB9811599D0 (en) 1998-05-30 1998-07-29 Glaxo Group Ltd Nitric oxide synthase inhibitors
JP2002517502A (ja) 1998-06-10 2002-06-18 ジー・ディー・サール・アンド・カンパニー 複素二環状及び三環状一酸化窒素シンターゼ阻害剤
US6344473B1 (en) 2000-08-07 2002-02-05 G.D. Searle & Co. Imidazoles useful as nitric oxide synthase inhibitors
CA2552195C (en) 2003-12-30 2012-01-24 Vasopharm Biotech Gmbh 4-amino-7,8-dihydropteridines, pharmaceutical compositions containing them and their use for the treatment of diseases which are caused by an increased nitric oxide level

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB931921A (en) * 1960-12-22 1963-07-24 Lab Roques Therapeutic compositions intended for the treatment of any hepatic malfunctionings
DE1767212B1 (de) * 1967-04-13 1971-05-06 Sumitomo Chemical Co Verfahren zur Herstellung injizierbarer Arzneimittel
FR2115060A1 (en) * 1970-11-26 1972-07-07 Metabio Freeze-dried acetylsalicylates of lysine and arginine - easily prepd derivs of aspirin
CA1029660A (en) * 1973-06-01 1978-04-18 Kyowa Hakko Kogyo Co. Prevention of gastric lesions
FR2320759A1 (fr) * 1975-08-11 1977-03-11 Union Pharma Scient Appl Solution d'acide acetylsalicylique extemporanee injectable
IT1127322B (it) * 1979-12-28 1986-05-21 Italfarmaco Spa Composizioni farmaceutiche con esaltazione dell'attivita' terapeutica di cortisonici
IT1127321B (it) * 1979-12-28 1986-05-21 Italfarmaco Spa Composizione farmaceutiche aventi specifiche proprieta' terapeutiche nei confronti dell'edema polmonare acuto,di alcuni stati di shock e dell'iperfibrinolisi
JPS5781409A (en) * 1980-11-10 1982-05-21 Toko Yakuhin Kogyo Kk External plaster
JPS57197211A (en) * 1981-05-28 1982-12-03 Sumitomo Chem Co Ltd Useful eye drop composition
JPS57200361A (en) * 1981-06-03 1982-12-08 Sumitomo Chem Co Ltd "indomethacin(r)" pharmaceutical with low irritant action
JPS6239524A (ja) * 1985-08-13 1987-02-20 Toko Yakuhin Kogyo Kk 消炎鎮痛軟膏剤
JPH0236570B2 (ja) * 1985-05-30 1990-08-17 Toko Yakuhin Kogyo Kk Shoenchintsunankozai
IT1201511B (it) * 1985-12-23 1989-02-02 Italfarmaco Spa Derivati citoprotettivi in patologie a base ischemica,loro preparazione e composizioni che li cntengono
AU1489688A (en) * 1987-02-20 1988-09-14 Shriners Hospitals For Crippled Children Omega-3 fatty acids in traumatic injury treatment

Also Published As

Publication number Publication date
ZA9010004B (en) 1991-10-30
OA09337A (fr) 1992-09-15
AT403122B (de) 1997-11-25
FR2656220A1 (fr) 1991-06-28
SE9003974L (sv) 1991-06-23
GB8929076D0 (en) 1990-02-28
KR950005866B1 (ko) 1995-06-02
GB2240041A (en) 1991-07-24
DE4041283A1 (de) 1991-06-27
JPH04364124A (ja) 1992-12-16
SE504922C2 (sv) 1997-05-26
JP2706578B2 (ja) 1998-01-28
KR910011253A (ko) 1991-08-07
CA2032904C (en) 1996-01-02
AU6837690A (en) 1991-06-27
MY105328A (en) 1994-09-30
SE9003974D0 (sv) 1990-12-12
US5081148A (en) 1992-01-14
NL194717C (nl) 2003-01-07
IE64403B1 (en) 1995-08-09
GB9028013D0 (en) 1991-02-13
DK304190D0 (da) 1990-12-21
DE4041283C2 (de) 2000-07-13
NL9002720A (nl) 1991-07-16
DK304190A (da) 1991-06-23
DK176168B1 (da) 2006-11-13
LU87867A1 (fr) 1991-05-07
HK134693A (en) 1993-12-17
GB2240041B (en) 1993-09-01
IT9022413A1 (it) 1991-06-23
IT1246511B (it) 1994-11-19
AU629777B2 (en) 1992-10-08
IT9022413A0 (it) 1990-12-18
FR2656220B1 (fr) 1995-01-13
BE1005531A5 (fr) 1993-09-28
CH681692A5 (nl) 1993-05-14
ATA260690A (de) 1997-04-15
CA2032904A1 (en) 1991-06-23
IE904592A1 (en) 1991-07-03

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Legal Events

Date Code Title Description
BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
V1 Lapsed because of non-payment of the annual fee

Effective date: 20100701