MA51552A - Anticorps anti-ox40 et procédés d'utilisation - Google Patents
Anticorps anti-ox40 et procédés d'utilisationInfo
- Publication number
- MA51552A MA51552A MA051552A MA51552A MA51552A MA 51552 A MA51552 A MA 51552A MA 051552 A MA051552 A MA 051552A MA 51552 A MA51552 A MA 51552A MA 51552 A MA51552 A MA 51552A
- Authority
- MA
- Morocco
- Prior art keywords
- antibodies
- methods
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/75—Agonist effect on antigen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201461973193P | 2014-03-31 | 2014-03-31 | |
US201461989448P | 2014-05-06 | 2014-05-06 | |
US201462073873P | 2014-10-31 | 2014-10-31 | |
US201462080171P | 2014-11-14 | 2014-11-14 |
Publications (1)
Publication Number | Publication Date |
---|---|
MA51552A true MA51552A (fr) | 2021-03-24 |
Family
ID=52829446
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA051552A MA51552A (fr) | 2014-03-31 | 2015-03-30 | Anticorps anti-ox40 et procédés d'utilisation |
MA40682A MA40682B1 (fr) | 2014-03-31 | 2015-03-30 | Anticorps anti-ox40 et procédés d'utilisation correspondants |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA40682A MA40682B1 (fr) | 2014-03-31 | 2015-03-30 | Anticorps anti-ox40 et procédés d'utilisation correspondants |
Country Status (29)
Country | Link |
---|---|
EP (2) | EP3632934A1 (fr) |
JP (2) | JP6637439B2 (fr) |
KR (1) | KR20160145624A (fr) |
CN (1) | CN106103486B (fr) |
AU (1) | AU2015241037B2 (fr) |
BR (1) | BR112016022658A2 (fr) |
CA (1) | CA2943262A1 (fr) |
CL (1) | CL2016002462A1 (fr) |
CR (1) | CR20160500A (fr) |
DK (1) | DK3126394T3 (fr) |
EA (1) | EA201691974A1 (fr) |
ES (1) | ES2763898T3 (fr) |
HR (1) | HRP20192285T1 (fr) |
HU (1) | HUE046767T2 (fr) |
IL (1) | IL247898A0 (fr) |
LT (1) | LT3126394T (fr) |
MA (2) | MA51552A (fr) |
MX (1) | MX2016012781A (fr) |
PE (2) | PE20161571A1 (fr) |
PH (1) | PH12016501894A1 (fr) |
PL (1) | PL3126394T3 (fr) |
PT (1) | PT3126394T (fr) |
RS (1) | RS59738B1 (fr) |
SG (1) | SG11201607969XA (fr) |
SI (1) | SI3126394T1 (fr) |
TW (1) | TWI680985B (fr) |
UA (1) | UA121112C2 (fr) |
WO (1) | WO2015153513A1 (fr) |
ZA (1) | ZA201606630B (fr) |
Families Citing this family (82)
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JP5401001B2 (ja) | 2002-09-11 | 2014-01-29 | ジェネンテック, インコーポレイテッド | 免疫関連疾患の治療のための新規組成物と方法 |
SG10201402815VA (en) | 2008-04-09 | 2014-09-26 | Genentech Inc | Novel compositions and methods for the treatment of immune related diseases |
RS57840B1 (sr) | 2013-03-18 | 2018-12-31 | Biocerox Prod Bv | Humanizovana anti-cd 134 (ox40) antitela i njihove upotrebe |
KR20160030936A (ko) | 2013-07-16 | 2016-03-21 | 제넨테크, 인크. | Pd-1 축 결합 길항제 및 tigit 억제제를 사용한 암을 치료하는 방법 |
WO2015153514A1 (fr) | 2014-03-31 | 2015-10-08 | Genentech, Inc. | Thérapie combinatoires comprenant des agents anti-angiogenèse et des agonistes se liant à ox40 |
CN114381521A (zh) | 2014-11-03 | 2022-04-22 | 豪夫迈·罗氏有限公司 | 用于ox40激动剂治疗的功效预测和评估的方法和生物标志物 |
CA2966523A1 (fr) | 2014-11-03 | 2016-05-12 | Genentech, Inc. | Tests de detection de sous-ensembles immunitaires de cellules t et leurs procedes d'utilisation |
RU2017119428A (ru) * | 2014-11-06 | 2018-12-06 | Дженентек, Инк. | Комбинированная терапия, включающая применение агонистов, связывающихся с ох40, и ингибиторов tigit |
SG11201708804WA (en) | 2015-05-07 | 2017-11-29 | Agenus Inc | Anti-ox40 antibodies and methods of use thereof |
CA2987410A1 (fr) | 2015-05-29 | 2016-12-08 | Bristol-Myers Squibb Company | Anticorps anti-ox40 et leurs utilisations |
EP3303399A1 (fr) * | 2015-06-08 | 2018-04-11 | H. Hoffnabb-La Roche Ag | Méthodes de traitement du cancer au moyen d'anticorps anti-ox40 |
CR20220186A (es) | 2015-09-25 | 2022-07-07 | Genentech Inc | ANTICUERPOS ANTI-TIGIT Y MÉTODOS DE USO (divisional 2018-0225) |
BR112018002570A2 (pt) | 2015-10-02 | 2018-10-16 | Hoffmann La Roche | molécula de ligação ao antígeno biespecífica, anticorpo biespecífico, polinucleotídeos, anticorpo que se liga especificamente ao ox40, composição farmacêutica e método para inibir o crescimento de células tumorais em um indivíduo |
CN108137684B (zh) * | 2015-10-15 | 2022-03-08 | 苏州丁孚靶点生物技术有限公司 | 抗ox40抗体及其应用 |
MA45488A (fr) | 2015-10-22 | 2018-08-29 | Juno Therapeutics Gmbh | Procédés, kits et appareil de culture de cellules |
CN108883173B (zh) * | 2015-12-02 | 2022-09-06 | 阿吉纳斯公司 | 抗体和其使用方法 |
AU2016364891A1 (en) * | 2015-12-03 | 2018-06-07 | Agenus Inc. | Anti-OX40 antibodies and methods of use thereof |
DE102016105069A1 (de) * | 2016-03-18 | 2017-09-21 | Eberhard Karls Universität Tübingen Medizinische Fakultät | Antivirale Immuntherapie durch Membranrezeptorligation |
KR20190005966A (ko) | 2016-05-10 | 2019-01-16 | 제넨테크, 인크. | 폴리펩타이드의 재조합 생산 동안 트리설파이드 결합을 감소시키기 위한 방법 |
TWI784957B (zh) | 2016-06-20 | 2022-12-01 | 英商克馬伯有限公司 | 免疫細胞介素 |
EP3494139B1 (fr) | 2016-08-05 | 2022-01-12 | F. Hoffmann-La Roche AG | Anticorps multivalents et multiépitopiques ayant une activité agoniste et procédés d'utilisation |
WO2018031490A2 (fr) * | 2016-08-08 | 2018-02-15 | Sorrento Therapeutics, Inc. | Protéines de liaison anti-ox40 |
CN107815465B (zh) | 2016-08-31 | 2021-03-16 | 百奥赛图(北京)医药科技股份有限公司 | 人源化基因改造动物模型的制备方法及应用 |
WO2018041119A1 (fr) | 2016-08-31 | 2018-03-08 | Beijing Biocytogen Co., Ltd | Animal non humain génétiquement modifié à ox40 humain ou chimérique |
CA3041340A1 (fr) | 2016-11-09 | 2018-05-17 | Agenus Inc. | Anticorps anti-ox40, anticorps anti-gitr, et leurs procedes d'utilisation |
US20200347143A1 (en) | 2016-12-19 | 2020-11-05 | Glenmark Pharmaceuticals S.A. | Novel tnfr agonists and uses thereof |
WO2018150326A1 (fr) | 2017-02-15 | 2018-08-23 | Glaxosmithkline Intellectual Property Development Limited | Polythérapie pour le traitement du cancer |
CN108623686A (zh) | 2017-03-25 | 2018-10-09 | 信达生物制药(苏州)有限公司 | 抗ox40抗体及其用途 |
WO2019089921A1 (fr) | 2017-11-01 | 2019-05-09 | Bristol-Myers Squibb Company | Anticorps agonistes immunostimulateurs destinés à être utilisés dans le traitement du cancer |
WO2019106605A1 (fr) | 2017-12-01 | 2019-06-06 | Board Of Regents, The University Of Texas System | Polythérapie pour le traitement du cancer |
US11142579B2 (en) | 2017-12-06 | 2021-10-12 | Sorrento Therapeutics, Inc. | Variant antibodies that bind OX40 |
WO2019129137A1 (fr) | 2017-12-27 | 2019-07-04 | 信达生物制药(苏州)有限公司 | Anticorps anti-lag-3 et utilisations associées |
CN109970856B (zh) | 2017-12-27 | 2022-08-23 | 信达生物制药(苏州)有限公司 | 抗lag-3抗体及其用途 |
WO2019129136A1 (fr) | 2017-12-27 | 2019-07-04 | 信达生物制药(苏州)有限公司 | Anticorps anti-pd-l1 et ses applications |
CN115925943A (zh) | 2017-12-27 | 2023-04-07 | 信达生物制药(苏州)有限公司 | 抗pd-l1抗体及其用途 |
EP4268848A3 (fr) * | 2017-12-29 | 2024-01-10 | AP Biosciences, Inc. | Protéines monospécifiques et bispécifiques à rôle de régulation de points de contrôle immunitaire destinées au traitement du cancer |
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TW202003555A (zh) | 2018-03-07 | 2020-01-16 | 英商葛蘭素史克智慧財產發展有限公司 | 用於純化重組多肽之方法 |
TW202003565A (zh) | 2018-03-23 | 2020-01-16 | 美商必治妥美雅史谷比公司 | 抗mica及/或micb抗體及其用途 |
WO2019191133A1 (fr) | 2018-03-27 | 2019-10-03 | Bristol-Myers Squibb Company | Surveillance en temps réel de la concentration de protéines à l'aide d'un signal ultraviolet |
AU2019245243A1 (en) | 2018-03-29 | 2020-09-03 | Genentech, Inc | Modulating lactogenic activity in mammalian cells |
CN110467674B (zh) | 2018-05-11 | 2022-05-31 | 同润澳门一人有限公司 | 抗ox40的全人抗体及其制备方法和用途 |
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SG11202100746WA (en) | 2018-07-25 | 2021-03-30 | Innovent Biologics Suzhou Co Ltd | Anti-tigit antibody and use thereof |
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EP3889180A4 (fr) * | 2018-11-26 | 2023-01-04 | Nanjing GenScript Biotech Co., Ltd. | Anticorps monoclonal humanisé anti-ox40, son procédé de préparation et son utilisation |
JP7346576B2 (ja) * | 2018-12-25 | 2023-09-19 | ハンクス バイオファーマシューティクス,インコーポレイテッド | 抗ox40モノクローナル抗体とその応用 |
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WO2020172658A1 (fr) | 2019-02-24 | 2020-08-27 | Bristol-Myers Squibb Company | Procédés d'isolement d'une protéine |
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KR20230056766A (ko) | 2020-08-28 | 2023-04-27 | 제넨테크, 인크. | 숙주 세포 단백질의 CRISPR/Cas9 다중 녹아웃 |
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EP4314068A1 (fr) | 2021-04-02 | 2024-02-07 | The Regents Of The University Of California | Anticorps dirigés contre un cdcp1 clivé et leurs utilisations |
TW202305122A (zh) | 2021-04-19 | 2023-02-01 | 美商建南德克公司 | 經修飾之哺乳動物細胞 |
KR20240010469A (ko) | 2021-05-21 | 2024-01-23 | 제넨테크, 인크. | 관심 재조합 생성물의 생성을 위한 변형된 세포 |
CN115403670A (zh) | 2021-05-26 | 2022-11-29 | 安徽瀚海博兴生物技术有限公司 | 抗cd40抗体及其用途 |
CN115611983A (zh) | 2021-07-14 | 2023-01-17 | 三优生物医药(上海)有限公司 | Cldn18.2结合分子及其用途 |
TW202323280A (zh) * | 2021-10-15 | 2023-06-16 | 新加坡商創響私人有限公司 | 包含抗-ox40單株抗體的藥物製劑 |
WO2023173011A1 (fr) | 2022-03-09 | 2023-09-14 | Bristol-Myers Squibb Company | Expression transitoire de protéines thérapeutiques |
WO2023178329A1 (fr) | 2022-03-18 | 2023-09-21 | Bristol-Myers Squibb Company | Procédés d'isolement de polypeptides |
WO2023235847A1 (fr) | 2022-06-02 | 2023-12-07 | Bristol-Myers Squibb Company | Compositions d'anticorps et leurs procédés d'utilisation |
WO2024054992A1 (fr) | 2022-09-09 | 2024-03-14 | Bristol-Myers Squibb Company | Procédés de séparation d'agent chélateur |
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