JP2002537264A - ベンズアルデヒド誘導体 - Google Patents

ベンズアルデヒド誘導体

Info

Publication number
JP2002537264A
JP2002537264A JP2000599401A JP2000599401A JP2002537264A JP 2002537264 A JP2002537264 A JP 2002537264A JP 2000599401 A JP2000599401 A JP 2000599401A JP 2000599401 A JP2000599401 A JP 2000599401A JP 2002537264 A JP2002537264 A JP 2002537264A
Authority
JP
Japan
Prior art keywords
compound
cells
cancer
cell
liver
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2000599401A
Other languages
English (en)
Japanese (ja)
Inventor
ベレツエン,ベルント
モエン,ヴイダル
ラルセン,ロルフ,オラフ
ペテルセン,エリク,オライ
サグヴオルデン,ギール
ダンセード,カミラ,ブルノ
Original Assignee
ノルスク ハイドロ アーエスアー
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ノルスク ハイドロ アーエスアー filed Critical ノルスク ハイドロ アーエスアー
Publication of JP2002537264A publication Critical patent/JP2002537264A/ja
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H9/00Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
    • C07H9/02Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical the hetero ring containing only oxygen as ring hetero atoms
    • C07H9/04Cyclic acetals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/18Acyclic radicals, substituted by carbocyclic rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Rheumatology (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP2000599401A 1999-02-19 2000-02-18 ベンズアルデヒド誘導体 Pending JP2002537264A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
NO990814A NO309305B1 (no) 1999-02-19 1999-02-19 Anvendelse av benzaldehydderivater ved fremstilling av farmasöytiske preparater for forebygging og/eller behandling av kreft, samt visse nye benzaldehydderivater
NO19990814 1999-02-19
PCT/NO2000/000060 WO2000048610A1 (en) 1999-02-19 2000-02-18 Chemical compounds

Publications (1)

Publication Number Publication Date
JP2002537264A true JP2002537264A (ja) 2002-11-05

Family

ID=19902986

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2000599400A Pending JP2002537263A (ja) 1999-02-19 2000-02-18 化学物質
JP2000599401A Pending JP2002537264A (ja) 1999-02-19 2000-02-18 ベンズアルデヒド誘導体

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2000599400A Pending JP2002537263A (ja) 1999-02-19 2000-02-18 化学物質

Country Status (15)

Country Link
EP (2) EP1150690A1 (pt)
JP (2) JP2002537263A (pt)
CN (2) CN1347323A (pt)
AU (2) AU2834200A (pt)
BR (2) BR0008302A (pt)
CA (2) CA2362306A1 (pt)
CZ (2) CZ20012965A3 (pt)
HU (2) HUP0105281A2 (pt)
IL (2) IL144895A0 (pt)
MX (2) MXPA01008346A (pt)
NO (1) NO309305B1 (pt)
PL (2) PL350519A1 (pt)
RU (2) RU2001123035A (pt)
SK (2) SK11602001A3 (pt)
WO (2) WO2000048609A1 (pt)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011516478A (ja) * 2008-04-03 2011-05-26 コグネイト 3,エルエルシー 免疫療法のための組成物および方法
JP2015178537A (ja) * 2002-12-19 2015-10-08 インファール・アクティエンゲゼルシャフト 重水素化カテコールアミン誘導体ならびにそれらの化合物を含有する医薬品
JP2017509686A (ja) * 2014-04-04 2017-04-06 イントラ−セルラー・セラピーズ・インコーポレイテッドIntra−Cellular Therapies, Inc. 有機化合物

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002096921A1 (fr) * 2001-05-30 2002-12-05 Nisshin Seifun Group Inc. Nouveau derive glucose induisant l'apoptose, procede de production et utilisation comme medicament
CN102134232B (zh) * 2005-07-26 2012-11-21 奈科明有限责任公司 同位素取代的质子泵抑制剂
AR054583A1 (es) * 2005-07-26 2007-06-27 Altana Pharma Ag Pantoprazol isotopicamente sustituido
WO2007041630A1 (en) * 2005-10-06 2007-04-12 Auspex Pharmaceuticals, Inc. Deuterated inhibitors of gastric h+, k+-atpase with enhanced therapeutic properties
CN101157711B (zh) * 2007-09-28 2010-12-08 西安交通大学 一种具有抗肿瘤活性的化合物及其用途
CN101735284B (zh) * 2008-11-24 2012-05-23 上海医药工业研究院 一种4,6-o-苄叉-d-吡喃葡萄糖的制备方法
CN114366741A (zh) 2013-12-03 2022-04-19 细胞内治疗公司 新方法
JP6898072B2 (ja) * 2015-08-27 2021-07-07 秀行 佐谷 14−3−3タンパク質活性調節剤
ES2879888T3 (es) 2016-03-25 2021-11-23 Intra Cellular Therapies Inc Compuestos orgánicos y su uso en el tratamiento o prevención de trastornos del sistema nervioso central
JP7013454B2 (ja) 2016-10-12 2022-02-15 イントラ-セルラー・セラピーズ・インコーポレイテッド アモルファス固体分散体
BR112019019875A2 (pt) 2017-03-24 2020-04-22 Intra Cellular Therapies Inc novas composições e métodos
BR112021003655A2 (pt) 2018-08-31 2021-05-18 Intra-Cellular Therapies, Inc. métodos novos
US10695345B2 (en) 2018-08-31 2020-06-30 Intra-Cellular Therapies, Inc. Pharmaceutical capsule compositions comprising lumateperone mono-tosylate

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB811510A (en) * 1954-12-20 1959-04-08 Gyogyszeripari Ki New nitrogen-containing derivatives of polyhydroxy compounds and process for the preparation thereof
JPS6112623A (ja) * 1984-06-28 1986-01-21 Kaken Pharmaceut Co Ltd エンケフアリナ−ゼ阻害剤
JPS6256423A (ja) * 1985-09-06 1987-03-12 Kaken Pharmaceut Co Ltd 悪液質治療改善剤
GB8705780D0 (en) * 1987-03-11 1987-04-15 Norsk Hydro As Anticancer compounds
JPH07145191A (ja) * 1993-11-24 1995-06-06 Japan Tobacco Inc ガラクトシルホスフォネート誘導体

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015178537A (ja) * 2002-12-19 2015-10-08 インファール・アクティエンゲゼルシャフト 重水素化カテコールアミン誘導体ならびにそれらの化合物を含有する医薬品
JP2011516478A (ja) * 2008-04-03 2011-05-26 コグネイト 3,エルエルシー 免疫療法のための組成物および方法
JP2017509686A (ja) * 2014-04-04 2017-04-06 イントラ−セルラー・セラピーズ・インコーポレイテッドIntra−Cellular Therapies, Inc. 有機化合物
JP2020079231A (ja) * 2014-04-04 2020-05-28 イントラ−セルラー・セラピーズ・インコーポレイテッドIntra−Cellular Therapies, Inc. 有機化合物

Also Published As

Publication number Publication date
HUP0105280A2 (hu) 2002-04-29
JP2002537263A (ja) 2002-11-05
NO990814D0 (no) 1999-02-19
NO309305B1 (no) 2001-01-15
IL144895A0 (en) 2002-06-30
MXPA01008346A (es) 2003-06-06
RU2001123124A (ru) 2004-02-20
CA2363670A1 (en) 2000-08-24
CN1347323A (zh) 2002-05-01
MXPA01008347A (es) 2004-03-10
PL350519A1 (en) 2002-12-16
IL144896A0 (en) 2002-06-30
WO2000048610A1 (en) 2000-08-24
CN1347322A (zh) 2002-05-01
CA2362306A1 (en) 2000-08-24
AU2834200A (en) 2000-09-04
WO2000048609A1 (en) 2000-08-24
HUP0105281A2 (hu) 2002-05-29
AU2834100A (en) 2000-09-04
RU2001123035A (ru) 2004-03-20
NO990814L (no) 2000-08-21
CZ20012965A3 (cs) 2002-03-13
PL350520A1 (en) 2002-12-16
BR0008302A (pt) 2002-08-27
SK11612001A3 (sk) 2002-04-04
CZ20012966A3 (cs) 2002-03-13
SK11602001A3 (sk) 2002-02-05
EP1150690A1 (en) 2001-11-07
BR0008297A (pt) 2002-05-28
EP1150689A1 (en) 2001-11-07

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