HUP0301092A2 - Vakcina - Google Patents
VakcinaInfo
- Publication number
- HUP0301092A2 HUP0301092A2 HU0301092A HUP0301092A HUP0301092A2 HU P0301092 A2 HUP0301092 A2 HU P0301092A2 HU 0301092 A HU0301092 A HU 0301092A HU P0301092 A HUP0301092 A HU P0301092A HU P0301092 A2 HUP0301092 A2 HU P0301092A2
- Authority
- HU
- Hungary
- Prior art keywords
- subject
- streptococcus pneumoniae
- pneumococcal
- immunogenic
- antigen
- Prior art date
Links
- 229960005486 vaccine Drugs 0.000 title 1
- 241000193998 Streptococcus pneumoniae Species 0.000 abstract 2
- 102000036639 antigens Human genes 0.000 abstract 2
- 108091007433 antigens Proteins 0.000 abstract 2
- 230000002163 immunogen Effects 0.000 abstract 2
- 238000002360 preparation method Methods 0.000 abstract 2
- 229940031000 streptococcus pneumoniae Drugs 0.000 abstract 2
- 101100453077 Botryococcus braunii HDR gene Proteins 0.000 abstract 1
- 206010033078 Otitis media Diseases 0.000 abstract 1
- 208000009362 Pneumococcal Pneumonia Diseases 0.000 abstract 1
- 206010035728 Pneumonia pneumococcal Diseases 0.000 abstract 1
- 230000029662 T-helper 1 type immune response Effects 0.000 abstract 1
- 239000002671 adjuvant Substances 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 150000004676 glycans Chemical class 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 229920001282 polysaccharide Polymers 0.000 abstract 1
- 239000005017 polysaccharide Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 208000022218 streptococcal pneumonia Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
- A61K39/092—Streptococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/0208—Specific bacteria not otherwise provided for
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/095—Neisseria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/102—Pasteurellales, e.g. Actinobacillus, Pasteurella; Haemophilus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/125—Picornaviridae, e.g. calicivirus
- A61K39/13—Poliovirus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/29—Hepatitis virus
- A61K39/292—Serum hepatitis virus, hepatitis B virus, e.g. Australia antigen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6068—Other bacterial proteins, e.g. OMP
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Virology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Pulmonology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
A találmány tárgya olyan immunogén készítményre vonatkozik, amelylegalább egy Streptococcus pneumoniae poliszacharid antigént és aPhtA, PhtD, PhtB, PhtE, SpsA, LytB, LytC, LytA, Sp125, Sp101, Sp128,Sp130 és Sp133 vagy ezek immunológiaialag funkcionális ekvivalenseközül választott legalább egy Streptococcus pneumoniae fehérjeantigént és adott esetben egy TH1- immunválaszt indukáló adjuvánsttartalmaz. A találmány tárgya továbbá az immunogén készítményekalkalmazása 55 év feletti idősekben pneumococcus okozta tüdőgyulladás,illetve csecsemőkben és kisgyerekekben pneumococcus okoztaközépfülgyulladás kezelésére vagy megelőzésére szolgáló gyógyszerelőállítására. Ó
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0022742.1A GB0022742D0 (en) | 2000-09-15 | 2000-09-15 | Vaccine |
PCT/EP2001/010568 WO2002022167A2 (en) | 2000-09-15 | 2001-09-12 | Vaccine against streptococcus penumoniae |
Publications (2)
Publication Number | Publication Date |
---|---|
HUP0301092A2 true HUP0301092A2 (hu) | 2003-09-29 |
HUP0301092A3 HUP0301092A3 (en) | 2011-03-28 |
Family
ID=9899575
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0301092A HUP0301092A3 (en) | 2000-09-15 | 2001-09-12 | Vaccine |
HU0301043A HUP0301043A3 (en) | 2000-09-15 | 2001-09-12 | Vaccine |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0301043A HUP0301043A3 (en) | 2000-09-15 | 2001-09-12 | Vaccine |
Country Status (25)
Country | Link |
---|---|
US (5) | US20040081662A1 (hu) |
EP (6) | EP1317280B1 (hu) |
JP (3) | JP4880184B2 (hu) |
KR (5) | KR101268790B1 (hu) |
CN (3) | CN101502648B (hu) |
AT (1) | ATE516815T1 (hu) |
AU (4) | AU3819302A (hu) |
BR (2) | BR0113821A (hu) |
CA (2) | CA2422002C (hu) |
CY (1) | CY1111915T1 (hu) |
CZ (2) | CZ305343B6 (hu) |
DK (1) | DK1317279T3 (hu) |
ES (4) | ES2545876T3 (hu) |
GB (1) | GB0022742D0 (hu) |
HK (1) | HK1057698A1 (hu) |
HU (2) | HUP0301092A3 (hu) |
IL (4) | IL154607A0 (hu) |
MX (2) | MXPA03002265A (hu) |
NO (2) | NO337730B1 (hu) |
NZ (2) | NZ524287A (hu) |
PL (2) | PL209247B1 (hu) |
PT (1) | PT1317279E (hu) |
SI (1) | SI1317279T1 (hu) |
WO (2) | WO2002022167A2 (hu) |
ZA (2) | ZA200301526B (hu) |
Families Citing this family (72)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7078042B2 (en) * | 1995-09-15 | 2006-07-18 | Uab Research Foundation | Pneumococcal surface protein C (PspC), epitopic regions and strain selection thereof, and uses therefor |
US7135560B1 (en) | 1997-07-02 | 2006-11-14 | Sanofi Pasteur Limited | Nucleic acid and amino acid sequences relating to Streptococcus pneumoniae for diagnostics and therapeutics |
US6800744B1 (en) | 1997-07-02 | 2004-10-05 | Genome Therapeutics Corporation | Nucleic acid and amino acid sequences relating to Streptococcus pneumoniae for diagnostics and therapeutics |
US7128918B1 (en) * | 1998-12-23 | 2006-10-31 | Id Biomedical Corporation | Streptococcus antigens |
TWI281403B (en) * | 1999-03-19 | 2007-05-21 | Smithkline Beecham Biolog | Vaccine |
US7074415B2 (en) * | 2000-06-20 | 2006-07-11 | Id Biomedical Corporation | Streptococcus antigens |
GB0115176D0 (en) | 2001-06-20 | 2001-08-15 | Chiron Spa | Capular polysaccharide solubilisation and combination vaccines |
EP1456231A2 (en) | 2001-12-20 | 2004-09-15 | Shire Biochem Inc. | Streptococcus antigens |
EP2275125A3 (en) * | 2002-04-02 | 2011-03-09 | Ben Gurion University Of The Negev Research And Development Authority | Protein-based streptococcus pneumoniae vaccines |
US8691243B2 (en) | 2002-04-02 | 2014-04-08 | Ben-Gurion University Of The Negev Research And Development Authority | Protein-based Streptococcus pneumoniae vaccine |
EP1549338B1 (en) | 2002-10-11 | 2010-12-22 | Novartis Vaccines and Diagnostics S.r.l. | Polypeptide-vaccines for broad protection against hypervirulent meningococcal lineages |
GB0227346D0 (en) | 2002-11-22 | 2002-12-31 | Chiron Spa | 741 |
US8229903B2 (en) * | 2002-12-19 | 2012-07-24 | International Business Machines Corporation | Suggesting data interpretations and patterns for updating policy documents |
ES2383175T3 (es) * | 2003-01-30 | 2012-06-18 | Novartis Ag | Vacunas inyectables contra múltiples serogrupos de meningococos |
NZ541969A (en) | 2003-03-13 | 2008-01-31 | Glaxosmithkline Biolog Sa | Purifying pneumolysin from Streptococcus pneumoniae in a single chromatographic step by binding it to a hydrophobic interaction column in the presence of detergent and high salt |
EP1477802A1 (en) * | 2003-05-16 | 2004-11-17 | Erasmus Universiteit Rotterdam | Method for selecting and producing vaccine components and vaccines based thereon |
CN103357002A (zh) | 2003-10-02 | 2013-10-23 | 诺华疫苗和诊断有限公司 | 多种脑膜炎球菌血清群的液体疫苗 |
GB0323103D0 (en) | 2003-10-02 | 2003-11-05 | Chiron Srl | De-acetylated saccharides |
WO2006034320A2 (en) * | 2004-09-21 | 2006-03-30 | Sanofi Pasteur, Inc. | Multivalent meningococcal derivatized polysaccharide-protein conjugates and vaccine |
AU2011253684B8 (en) * | 2005-04-08 | 2013-07-11 | Wyeth Llc | Multivalent pneumococcal polysaccharide-protein conjugate composition |
TWI445545B (zh) | 2005-04-08 | 2014-07-21 | Wyeth Corp | 多價肺炎球菌多醣-蛋白質共軛物組合物 |
GB0522765D0 (en) | 2005-11-08 | 2005-12-14 | Chiron Srl | Combination vaccine manufacture |
GB0524066D0 (en) | 2005-11-25 | 2006-01-04 | Chiron Srl | 741 ii |
TWI457133B (zh) | 2005-12-13 | 2014-10-21 | Glaxosmithkline Biolog Sa | 新穎組合物 |
CA2633772C (en) | 2005-12-22 | 2015-09-15 | Ralph Leon Biemans | Pneumococcal polysaccharide conjugate vaccine |
AU2006336520B2 (en) * | 2005-12-28 | 2011-09-15 | The Uab Research Foundation | Pneumococcal serotypes |
US8808707B1 (en) | 2006-05-08 | 2014-08-19 | Wyeth Llc | Pneumococcal dosing regimen |
BRPI0715975A2 (pt) * | 2006-08-17 | 2014-03-18 | Uab Res Foudation | Fragmento imunogênico de pcpa, composição,recipiente, métodos de gerar anticorpos específicos para pcpa em um indivíduo, de prevenir ou reduzir portador nasal pneumocócico em um indivíduo, e de reduzir o risco de uma infecção pneumocócica em um indivíduo, e, polipeptídeo isolado |
DK2148697T3 (da) * | 2007-05-24 | 2012-12-17 | Glaxosmithkline Biolog Sa | Lyofiliseret CPG indeholdende WT-1-sammensætning |
BRPI0813307C1 (pt) | 2007-06-26 | 2021-05-25 | Glaxosmithkline Biologicals Sa | composição imunogênica, vacina, e, processo para fabricar a vacina |
GB0713880D0 (en) | 2007-07-17 | 2007-08-29 | Novartis Ag | Conjugate purification |
US20160228500A9 (en) * | 2007-07-23 | 2016-08-11 | Martina Ochs | Immunogenic Polypeptides and Monoclonal Antibodies |
BRPI0814127A2 (pt) | 2007-07-23 | 2015-02-03 | Sanofi Pasteur Ltd | Polipeptídeos imunegênicos e anticorpos monoclonais |
GB0714963D0 (en) | 2007-08-01 | 2007-09-12 | Novartis Ag | Compositions comprising antigens |
CA2699225A1 (en) * | 2007-09-14 | 2009-03-19 | Katholieke Universiteit Leuven | Streptococcus pneumoniae vaccines |
EP2235531B1 (en) * | 2008-02-01 | 2015-01-14 | Sanofi Pasteur Limited | Assay for diagnosing streptococcus pneumoniae |
MX2010009738A (es) | 2008-03-03 | 2010-09-30 | Irm Llc | Compuestos y composiciones como moduladores de la actividad de tlr. |
CN102438649A (zh) | 2009-03-24 | 2012-05-02 | 诺华有限公司 | 脑膜炎球菌h因子结合蛋白和肺炎球菌结合糖的组合物 |
TR201802380T4 (tr) | 2009-06-10 | 2018-03-21 | Glaxosmithkline Biologicals Sa | Benzonaftiridin içeren aşılar. |
TWI445708B (zh) | 2009-09-02 | 2014-07-21 | Irm Llc | 作為tlr活性調節劑之化合物及組合物 |
US9950062B2 (en) | 2009-09-02 | 2018-04-24 | Glaxosmithkline Biologicals Sa | Compounds and compositions as TLR activity modulators |
CN102695523A (zh) | 2009-09-10 | 2012-09-26 | 诺华有限公司 | 针对呼吸道疾病的组合疫苗 |
CN101690810B (zh) * | 2009-10-21 | 2011-08-17 | 辽宁益康生物股份有限公司 | 一种鸡新城疫、传染性支气管炎、减蛋综合征、禽流感四联灭活疫苗佐剂及其制备方法 |
WO2011057148A1 (en) | 2009-11-05 | 2011-05-12 | Irm Llc | Compounds and compositions as tlr-7 activity modulators |
EP2512478B1 (en) | 2009-12-15 | 2017-04-19 | GlaxoSmithKline Biologicals SA | Homogeneous suspension of immunopotentiating compounds and uses thereof |
WO2011075822A1 (en) | 2009-12-22 | 2011-06-30 | Sanofi Pasteur Limited | Immunogenic compositions and related methods |
AU2010335970B2 (en) * | 2009-12-22 | 2016-11-03 | Sanofi Pasteur Limited | Immunogenic compositions |
GB201003922D0 (en) | 2010-03-09 | 2010-04-21 | Glaxosmithkline Biolog Sa | Conjugation process |
GB201003920D0 (en) | 2010-03-09 | 2010-04-21 | Glaxosmithkline Biolog Sa | Method of treatment |
JP5848748B2 (ja) | 2010-03-23 | 2016-01-27 | アイアールエム・リミテッド・ライアビリティ・カンパニーIrm,Llc | 感染症、炎症、呼吸器疾患などの処置に使用するtlr2アゴニストとしての化合物(システインベースのリポペプチド)および組成物 |
WO2012072769A1 (en) | 2010-12-01 | 2012-06-07 | Novartis Ag | Pneumococcal rrgb epitopes and clade combinations |
CA2819758A1 (en) * | 2010-12-03 | 2012-06-07 | Sanofi Pasteur Limited | Composition for immunization against streptococcus pneumoniae |
MX339058B (es) * | 2011-05-17 | 2016-05-09 | Glaxosmithkline Biolog Sa | Vacuna contra streptococcus pneumoniae. |
EP2822586A1 (en) | 2012-03-07 | 2015-01-14 | Novartis AG | Adjuvanted formulations of streptococcus pneumoniae antigens |
JP2014000016A (ja) * | 2012-06-15 | 2014-01-09 | National Agriculture & Food Research Organization | 豚丹毒菌の新規な抗原タンパク質、その遺伝子、及び組換えベクターとその利用 |
RU2510281C2 (ru) * | 2012-06-22 | 2014-03-27 | Общество с ограниченной ответственностью "Эпитоп" (ООО "Эпитоп") | ВАКЦИНА ПРОТИВ ПНЕВМОНИИ, ВЫЗЫВАЕМОЙ Streptococcus pneumoniae, НА ОСНОВЕ ГИБРИДНОГО БЕЛКА |
KR20150058571A (ko) * | 2012-10-17 | 2015-05-28 | 글락소스미스클라인 바이오로지칼즈 에스.에이. | 면역원성 조성물 |
GB201218660D0 (en) | 2012-10-17 | 2012-11-28 | Glaxosmithkline Biolog Sa | Immunogenic composition |
CN104870193B (zh) | 2013-01-01 | 2017-12-22 | 爱克发印艺公司 | (乙烯、乙烯醇缩醛)共聚物和它们在平版印刷版前体中的用途 |
EP2950819B1 (en) | 2013-02-01 | 2018-03-28 | GlaxoSmithKline Biologicals SA | Intradermal delivery of immunological compositions comprising toll-like receptor agonists |
US11160855B2 (en) | 2014-01-21 | 2021-11-02 | Pfizer Inc. | Immunogenic compositions comprising conjugated capsular saccharide antigens and uses thereof |
US20150344530A1 (en) * | 2014-05-29 | 2015-12-03 | Subhash V. Kapre | Synthetic Peptides as Carriers for Conjugation with Polysaccharides |
US9815886B2 (en) | 2014-10-28 | 2017-11-14 | Adma Biologics, Inc. | Compositions and methods for the treatment of immunodeficiency |
BR112018068753A2 (pt) | 2016-03-16 | 2019-01-22 | Agfa Nv | método para processar uma chapa de impressão litográfica |
WO2018124959A2 (en) * | 2016-12-28 | 2018-07-05 | Henriques Normark Birgitta | Microparticles from streptococcus pneumoniae as vaccine antigens |
US10259865B2 (en) | 2017-03-15 | 2019-04-16 | Adma Biologics, Inc. | Anti-pneumococcal hyperimmune globulin for the treatment and prevention of pneumococcal infection |
AU2018280272C1 (en) | 2017-06-10 | 2021-05-06 | Inventprise, Inc. | Multivalent conjugate vaccines with bivalent or multivalent conjugate polysaccharides that provide improved immunogenicity and avidity |
US10729763B2 (en) | 2017-06-10 | 2020-08-04 | Inventprise, Llc | Mixtures of polysaccharide-protein pegylated compounds |
JP7362667B2 (ja) | 2018-02-12 | 2023-10-17 | イニミューン・コーポレーション | Toll様受容体リガンド |
WO2020183420A1 (en) * | 2019-03-13 | 2020-09-17 | St. Jude Children's Research Hospital | Vaccine compositions and methods for reducing transmission of streptococcus pneumoniae |
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EP4240841A1 (en) | 2020-11-04 | 2023-09-13 | Eligo Bioscience | Phage-derived particles for in situ delivery of dna payload into c. acnes population |
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