MX339058B - Vacuna contra streptococcus pneumoniae. - Google Patents
Vacuna contra streptococcus pneumoniae.Info
- Publication number
- MX339058B MX339058B MX2013013444A MX2013013444A MX339058B MX 339058 B MX339058 B MX 339058B MX 2013013444 A MX2013013444 A MX 2013013444A MX 2013013444 A MX2013013444 A MX 2013013444A MX 339058 B MX339058 B MX 339058B
- Authority
- MX
- Mexico
- Prior art keywords
- streptococcus pneumoniae
- vaccine against
- against streptococcus
- relates
- immunogenic compositions
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
- A61K39/092—Streptococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55577—Saponins; Quil A; QS21; ISCOMS
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dispersion Chemistry (AREA)
- Organic Chemistry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Biochemistry (AREA)
- Dermatology (AREA)
- Molecular Biology (AREA)
- Pulmonology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
Abstract
La presente invención se refiere a composiciones inmunogénicas y vacunas mejoradas, a procedimientos para prepararlas y a su uso en medicina. En particular, la invención se refiere a composiciones inmunogénicas de proteínas de Streptococcus pneumoniae sin conjugar seleccionadas de: neumolisina y miembro(s) de la familia tríada de polihistidina (por ejemplo, PhtD) que comprenden adyuvantes que comprenden QS21 y lípido de monofosforilo A (MPL), y se presentan en forma de un liposoma.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB1108256.7A GB201108256D0 (en) | 2011-05-17 | 2011-05-17 | Vaccine |
GBGB1121647.0A GB201121647D0 (en) | 2011-12-16 | 2011-12-16 | Vaccine |
PCT/EP2012/058987 WO2012156391A1 (en) | 2011-05-17 | 2012-05-15 | Vaccine against streptococcus pneumoniae |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2013013444A MX2013013444A (es) | 2013-12-06 |
MX339058B true MX339058B (es) | 2016-05-09 |
Family
ID=46062296
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2013013444A MX339058B (es) | 2011-05-17 | 2012-05-15 | Vacuna contra streptococcus pneumoniae. |
Country Status (17)
Country | Link |
---|---|
US (1) | US20140072622A1 (es) |
EP (1) | EP2709658A1 (es) |
JP (1) | JP2014515035A (es) |
KR (1) | KR20140033127A (es) |
CN (1) | CN103533953A (es) |
AR (1) | AR086405A1 (es) |
AU (1) | AU2012257771C1 (es) |
BR (1) | BR112013029514A2 (es) |
CA (1) | CA2834834A1 (es) |
EA (1) | EA201391456A1 (es) |
IL (1) | IL229051A0 (es) |
MX (1) | MX339058B (es) |
SG (1) | SG194733A1 (es) |
TW (1) | TW201309327A (es) |
UY (1) | UY34073A (es) |
WO (1) | WO2012156391A1 (es) |
ZA (1) | ZA201308537B (es) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20150058571A (ko) * | 2012-10-17 | 2015-05-28 | 글락소스미스클라인 바이오로지칼즈 에스.에이. | 면역원성 조성물 |
GB201218660D0 (en) | 2012-10-17 | 2012-11-28 | Glaxosmithkline Biolog Sa | Immunogenic composition |
CA3003483C (en) | 2015-11-06 | 2022-09-13 | Adjuvance Technologies, Inc. | Triterpene saponin analogues |
WO2018124959A2 (en) * | 2016-12-28 | 2018-07-05 | Henriques Normark Birgitta | Microparticles from streptococcus pneumoniae as vaccine antigens |
WO2018217882A1 (en) * | 2017-05-23 | 2018-11-29 | EMULATE, Inc. | Advanced pulmonary models |
JP2020536946A (ja) * | 2017-10-16 | 2020-12-17 | アジュバンス・テクノロジーズ・インコーポレーテッド | トリテルペンサポニン類似物 |
EP4346896A1 (en) * | 2021-05-27 | 2024-04-10 | Revelation Biosciences, Inc. | Mpla compositions and methods of use |
CN116212012A (zh) * | 2021-12-02 | 2023-06-06 | 上海泽润生物科技有限公司 | 复合佐剂以及包含它的疫苗制剂 |
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GB0724357D0 (en) | 2007-12-14 | 2008-01-23 | Glaxosmithkline Biolog Sa | Method for preparing protein conjugates |
ES2331863B1 (es) | 2008-07-15 | 2010-10-27 | Consejo Superior De Investigaciones Cientificas (Csic) | Bacterias y productos derivados para fortalecer las defensas y reducir el riesgo de enfermedad. |
CN102712680B (zh) * | 2008-12-24 | 2016-06-22 | 荷兰王国卫生福利和运动部国家公共卫生和环境研究所 | 修饰的肺炎链球菌溶血素(ply)多肽 |
WO2010109325A2 (en) | 2009-03-24 | 2010-09-30 | Novartis Ag | Combinations including pneumococcal serotype 14 saccharide |
EP2437777B1 (en) | 2009-06-01 | 2014-09-17 | Novartis AG | COMBINATIONS OF PNEUMOCOCCAL RrgB CLADES |
AU2010335970B2 (en) | 2009-12-22 | 2016-11-03 | Sanofi Pasteur Limited | Immunogenic compositions |
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2012
- 2012-05-15 MX MX2013013444A patent/MX339058B/es active IP Right Grant
- 2012-05-15 KR KR1020137033256A patent/KR20140033127A/ko not_active Application Discontinuation
- 2012-05-15 AU AU2012257771A patent/AU2012257771C1/en not_active Ceased
- 2012-05-15 EA EA201391456A patent/EA201391456A1/ru unknown
- 2012-05-15 SG SG2013080973A patent/SG194733A1/en unknown
- 2012-05-15 AR ARP120101714A patent/AR086405A1/es unknown
- 2012-05-15 CA CA2834834A patent/CA2834834A1/en not_active Abandoned
- 2012-05-15 BR BR112013029514A patent/BR112013029514A2/pt not_active IP Right Cessation
- 2012-05-15 UY UY0001034073A patent/UY34073A/es not_active Application Discontinuation
- 2012-05-15 US US14/118,387 patent/US20140072622A1/en not_active Abandoned
- 2012-05-15 JP JP2014510771A patent/JP2014515035A/ja not_active Ceased
- 2012-05-15 WO PCT/EP2012/058987 patent/WO2012156391A1/en active Application Filing
- 2012-05-15 TW TW101117268A patent/TW201309327A/zh unknown
- 2012-05-15 CN CN201280023465.8A patent/CN103533953A/zh active Pending
- 2012-05-15 EP EP12720518.5A patent/EP2709658A1/en not_active Ceased
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2013
- 2013-10-24 IL IL229051A patent/IL229051A0/en unknown
- 2013-11-13 ZA ZA2013/08537A patent/ZA201308537B/en unknown
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TW201309327A (zh) | 2013-03-01 |
AU2012257771A1 (en) | 2013-04-04 |
CN103533953A (zh) | 2014-01-22 |
ZA201308537B (en) | 2015-08-26 |
SG194733A1 (en) | 2013-12-30 |
MX2013013444A (es) | 2013-12-06 |
AU2012257771C1 (en) | 2015-12-03 |
AU2012257771B2 (en) | 2015-01-15 |
BR112013029514A2 (pt) | 2019-09-24 |
CA2834834A1 (en) | 2012-11-22 |
EA201391456A1 (ru) | 2014-05-30 |
AR086405A1 (es) | 2013-12-11 |
US20140072622A1 (en) | 2014-03-13 |
JP2014515035A (ja) | 2014-06-26 |
EP2709658A1 (en) | 2014-03-26 |
KR20140033127A (ko) | 2014-03-17 |
UY34073A (es) | 2013-01-03 |
WO2012156391A1 (en) | 2012-11-22 |
IL229051A0 (en) | 2013-12-31 |
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