HK1125823A1 - 吡啶並吡嗪衍生物及其作為信號轉導途徑調節劑的應用 - Google Patents
吡啶並吡嗪衍生物及其作為信號轉導途徑調節劑的應用Info
- Publication number
- HK1125823A1 HK1125823A1 HK09102357.4A HK09102357A HK1125823A1 HK 1125823 A1 HK1125823 A1 HK 1125823A1 HK 09102357 A HK09102357 A HK 09102357A HK 1125823 A1 HK1125823 A1 HK 1125823A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- modulators
- signal transduction
- transduction paths
- pyridopyrazine derivatives
- pyridopyrazine
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
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- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US73570705P | 2005-11-11 | 2005-11-11 | |
EP05024692A EP1790342A1 (de) | 2005-11-11 | 2005-11-11 | Pyridopyrazin-Derivate und deren Verwendung als Modulatoren der Signaltransduktionswege |
PCT/EP2006/068323 WO2007079999A2 (de) | 2005-11-11 | 2006-11-10 | Pyridopyrazin-derivate und deren verwendung als modulatoren der signaltransduktionswege |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1125823A1 true HK1125823A1 (zh) | 2009-08-21 |
Family
ID=36424666
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK09102357.4A HK1125823A1 (zh) | 2005-11-11 | 2009-03-12 | 吡啶並吡嗪衍生物及其作為信號轉導途徑調節劑的應用 |
Country Status (21)
Country | Link |
---|---|
US (1) | US8937068B2 (zh) |
EP (2) | EP1790342A1 (zh) |
JP (1) | JP5448450B2 (zh) |
KR (1) | KR101473662B1 (zh) |
CN (1) | CN101330918B (zh) |
AR (1) | AR056216A1 (zh) |
AU (1) | AU2006334721B2 (zh) |
BR (1) | BRPI0618451A2 (zh) |
CA (1) | CA2628186A1 (zh) |
ES (1) | ES2543962T3 (zh) |
HK (1) | HK1125823A1 (zh) |
IL (1) | IL191160A (zh) |
NO (1) | NO20082509L (zh) |
NZ (1) | NZ595879A (zh) |
PL (1) | PL1962854T3 (zh) |
RU (1) | RU2487713C2 (zh) |
SG (1) | SG10201401061XA (zh) |
TW (1) | TWI423973B (zh) |
UA (1) | UA95464C2 (zh) |
WO (1) | WO2007079999A2 (zh) |
ZA (1) | ZA200803867B (zh) |
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CN101932609B (zh) * | 2007-12-04 | 2016-03-23 | 罗格斯新泽西州立大学 | 用以调节细胞膜重封的组合物和方法 |
US8399483B2 (en) | 2007-12-21 | 2013-03-19 | Ucb Pharma S.A. | Quinoxaline and quinoline derivatives as kinase inhibitors |
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WO2010052448A2 (en) * | 2008-11-05 | 2010-05-14 | Ucb Pharma S.A. | Fused pyrazine derivatives as kinase inhibitors |
GB201007286D0 (en) | 2010-04-30 | 2010-06-16 | Astex Therapeutics Ltd | New compounds |
US20130123340A1 (en) * | 2010-05-11 | 2013-05-16 | Peking University, Office Of Technology Transfer | Compositions and methods for the treatment and prevention of cardiac ischemic injury |
KR101496794B1 (ko) | 2010-11-05 | 2015-02-27 | 유니버시티 오브 메디신 앤드 덴티스트리 오브 뉴 저지 | 조직 손상에 대한 진단 마커로서의 혈청 mg53 |
GB201020179D0 (en) | 2010-11-29 | 2011-01-12 | Astex Therapeutics Ltd | New compounds |
EP2508184A1 (en) * | 2011-04-06 | 2012-10-10 | Æterna Zentaris GmbH | Pyridopyrazine derivatives and their use |
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GB201118654D0 (en) | 2011-10-28 | 2011-12-07 | Astex Therapeutics Ltd | New compounds |
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WO2014109414A1 (ja) * | 2013-01-11 | 2014-07-17 | 富士フイルム株式会社 | 含窒素複素環化合物またはその塩 |
GB201307577D0 (en) | 2013-04-26 | 2013-06-12 | Astex Therapeutics Ltd | New compounds |
HUE053654T2 (hu) | 2014-03-26 | 2021-07-28 | Astex Therapeutics Ltd | FGFR- és CMET-inhibitorok kombinációi a rák kezelésére |
JO3512B1 (ar) | 2014-03-26 | 2020-07-05 | Astex Therapeutics Ltd | مشتقات كينوكسالين مفيدة كمعدلات لإنزيم fgfr كيناز |
RU2715893C2 (ru) | 2014-03-26 | 2020-03-04 | Астекс Терапьютикс Лтд | Комбинации ингибитора fgfr и ингибитора igf1r |
JOP20200201A1 (ar) | 2015-02-10 | 2017-06-16 | Astex Therapeutics Ltd | تركيبات صيدلانية تشتمل على n-(3.5- ثنائي ميثوكسي فينيل)-n'-(1-ميثيل إيثيل)-n-[3-(ميثيل-1h-بيرازول-4-يل) كينوكسالين-6-يل]إيثان-1.2-ثنائي الأمين |
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EP3353164B1 (en) | 2015-09-23 | 2021-11-03 | Janssen Pharmaceutica, N.V. | Bi-heteroaryl substituted 1,4-benzodiazepines and uses thereof for the treatment of cancer |
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2005
- 2005-11-11 EP EP05024692A patent/EP1790342A1/de not_active Withdrawn
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2006
- 2006-10-11 UA UAA200807895A patent/UA95464C2/ru unknown
- 2006-11-10 AU AU2006334721A patent/AU2006334721B2/en not_active Ceased
- 2006-11-10 US US11/558,493 patent/US8937068B2/en not_active Expired - Fee Related
- 2006-11-10 TW TW095141709A patent/TWI423973B/zh not_active IP Right Cessation
- 2006-11-10 EP EP06849272.7A patent/EP1962854B1/de active Active
- 2006-11-10 CA CA002628186A patent/CA2628186A1/en not_active Abandoned
- 2006-11-10 ES ES06849272.7T patent/ES2543962T3/es active Active
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- 2006-11-10 WO PCT/EP2006/068323 patent/WO2007079999A2/de active Application Filing
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Also Published As
Publication number | Publication date |
---|---|
CA2628186A1 (en) | 2007-07-19 |
WO2007079999A2 (de) | 2007-07-19 |
JP2009515854A (ja) | 2009-04-16 |
US20070123494A1 (en) | 2007-05-31 |
IL191160A0 (en) | 2008-12-29 |
EP1962854A2 (de) | 2008-09-03 |
IL191160A (en) | 2016-03-31 |
KR20080068116A (ko) | 2008-07-22 |
EP1790342A1 (de) | 2007-05-30 |
TW200736253A (en) | 2007-10-01 |
CN101330918B (zh) | 2015-09-02 |
JP5448450B2 (ja) | 2014-03-19 |
EP1962854B1 (de) | 2015-05-06 |
KR101473662B1 (ko) | 2014-12-17 |
ZA200803867B (en) | 2009-05-27 |
AR056216A1 (es) | 2007-09-26 |
NZ595879A (en) | 2013-07-26 |
PL1962854T3 (pl) | 2015-10-30 |
TWI423973B (zh) | 2014-01-21 |
ES2543962T3 (es) | 2015-08-26 |
AU2006334721B2 (en) | 2011-08-11 |
UA95464C2 (en) | 2011-08-10 |
BRPI0618451A2 (pt) | 2011-08-30 |
WO2007079999A3 (de) | 2007-10-04 |
RU2008123219A (ru) | 2009-12-20 |
SG10201401061XA (en) | 2014-07-30 |
US8937068B2 (en) | 2015-01-20 |
RU2487713C2 (ru) | 2013-07-20 |
NO20082509L (no) | 2008-07-23 |
CN101330918A (zh) | 2008-12-24 |
AU2006334721A1 (en) | 2007-07-19 |
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