HK1061029A1 - Rho-kinase inhibitors - Google Patents
Rho-kinase inhibitorsInfo
- Publication number
- HK1061029A1 HK1061029A1 HK04104114A HK04104114A HK1061029A1 HK 1061029 A1 HK1061029 A1 HK 1061029A1 HK 04104114 A HK04104114 A HK 04104114A HK 04104114 A HK04104114 A HK 04104114A HK 1061029 A1 HK1061029 A1 HK 1061029A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- rho
- kinase inhibitors
- kinase
- inhibitors
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US27797401P | 2001-03-23 | 2001-03-23 | |
| US31533801P | 2001-08-29 | 2001-08-29 | |
| PCT/US2002/008660 WO2002076977A2 (en) | 2001-03-23 | 2002-03-22 | Rho-kinase inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1061029A1 true HK1061029A1 (en) | 2004-09-03 |
Family
ID=26958818
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK04104114A HK1061029A1 (en) | 2001-03-23 | 2004-06-09 | Rho-kinase inhibitors |
Country Status (19)
| Country | Link |
|---|---|
| US (3) | US20030087919A1 (xx) |
| EP (1) | EP1370552B1 (xx) |
| JP (1) | JP4320705B2 (xx) |
| AR (1) | AR035792A1 (xx) |
| AT (1) | ATE353889T1 (xx) |
| AU (1) | AU2002245709A1 (xx) |
| CA (1) | CA2441501C (xx) |
| CY (1) | CY1108041T1 (xx) |
| DE (1) | DE60218138T2 (xx) |
| DK (1) | DK1370552T3 (xx) |
| ES (1) | ES2280517T3 (xx) |
| HK (1) | HK1061029A1 (xx) |
| MX (1) | MXPA03008659A (xx) |
| MY (1) | MY142915A (xx) |
| PE (1) | PE20020958A1 (xx) |
| PT (1) | PT1370552E (xx) |
| TW (1) | TWI336328B (xx) |
| UY (1) | UY27225A1 (xx) |
| WO (1) | WO2002076977A2 (xx) |
Families Citing this family (81)
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| US8124630B2 (en) | 1999-01-13 | 2012-02-28 | Bayer Healthcare Llc | ω-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors |
| JP4636486B2 (ja) | 2002-02-11 | 2011-02-23 | バイエル、ファーマシューテイカルズ、コーポレイション | 脈管形成阻害活性を有するアリール尿素 |
| US7645878B2 (en) | 2002-03-22 | 2010-01-12 | Bayer Healthcare Llc | Process for preparing quinazoline Rho-kinase inhibitors and intermediates thereof |
| ES2382733T3 (es) | 2002-08-29 | 2012-06-13 | Santen Pharmaceutical Co., Ltd. | Remedio para el glaucoma que comprende un inhibidor de la Rho quinasa y prostaglandinas |
| GB0307333D0 (en) * | 2003-03-29 | 2003-05-07 | Astrazeneca Ab | Therapeutic agent |
| ES2370245T3 (es) * | 2003-04-18 | 2011-12-13 | Senju Pharmaceutical Co., Ltd. | 2-cloro-6,7-dimetoxi-n-[5-(1)h-indazolil]quinazolina-4-amina, dihidrocloruro de n-(1-bencil-4-piperidinil)-1h-indazol-5-amina, ácido 4-[2-(2,3,4,5,6-pentafluorofenil)acriloil]cinámico e hidrocloruro de fasudilo para uso en la recuperación de la percepción corneal. |
| ATE366108T1 (de) | 2003-05-20 | 2007-07-15 | Bayer Pharmaceuticals Corp | Diaryl-harnstoffe für durch pdgfr vermittelte krankheiten |
| PL1663978T3 (pl) | 2003-07-23 | 2008-04-30 | Bayer Healthcare Llc | Fluoropodstawiony omega-karboksyarylodifenylomocznik do leczenia i profilaktyki chorób i stanów |
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| WO2008054599A2 (en) * | 2006-09-27 | 2008-05-08 | Surface Logix, Inc. | Rho kinase inhibitors |
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| WO2022259721A1 (ja) | 2021-06-10 | 2022-12-15 | 味の素株式会社 | 間葉系幹細胞の製造方法 |
| WO2023017848A1 (ja) | 2021-08-11 | 2023-02-16 | 国立大学法人京都大学 | 腎間質前駆細胞の製造方法並びにエリスロポエチン産生細胞、およびレニン産生細胞の製造方法 |
| CA3231501A1 (en) | 2021-09-13 | 2023-03-16 | Steven Kattman | Methods for the production of committed cardiac progenitor cells |
| WO2024073776A1 (en) | 2022-09-30 | 2024-04-04 | FUJIFILM Cellular Dynamics, Inc. | Methods for the production of cardiac fibroblasts |
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2002
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- 2002-03-22 UY UY27225A patent/UY27225A1/es unknown
- 2002-03-22 US US10/103,565 patent/US20030087919A1/en not_active Abandoned
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- 2002-03-22 WO PCT/US2002/008660 patent/WO2002076977A2/en active IP Right Grant
- 2002-03-22 EP EP02713884A patent/EP1370552B1/en not_active Expired - Lifetime
- 2002-03-22 DE DE60218138T patent/DE60218138T2/de not_active Expired - Lifetime
- 2002-03-22 MY MYPI20021019A patent/MY142915A/en unknown
- 2002-03-22 TW TW091105577A patent/TWI336328B/zh not_active IP Right Cessation
- 2002-03-22 AU AU2002245709A patent/AU2002245709A1/en not_active Abandoned
- 2002-03-22 AT AT02713884T patent/ATE353889T1/de active
- 2002-03-22 PT PT02713884T patent/PT1370552E/pt unknown
- 2002-03-22 DK DK02713884T patent/DK1370552T3/da active
- 2002-03-22 ES ES02713884T patent/ES2280517T3/es not_active Expired - Lifetime
- 2002-03-22 PE PE2002000225A patent/PE20020958A1/es not_active Application Discontinuation
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- 2007-04-19 CY CY20071100536T patent/CY1108041T1/el unknown
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Also Published As
| Publication number | Publication date |
|---|---|
| ES2280517T3 (es) | 2007-09-16 |
| PE20020958A1 (es) | 2002-11-14 |
| WO2002076977A3 (en) | 2002-12-12 |
| MY142915A (en) | 2011-01-31 |
| DE60218138T2 (de) | 2007-09-20 |
| CA2441501A1 (en) | 2002-10-03 |
| EP1370552B1 (en) | 2007-02-14 |
| TWI336328B (en) | 2011-01-21 |
| CY1108041T1 (el) | 2013-09-04 |
| CA2441501C (en) | 2010-09-14 |
| DK1370552T3 (da) | 2007-05-07 |
| UY27225A1 (es) | 2002-10-31 |
| PT1370552E (pt) | 2007-04-30 |
| AU2002245709A1 (en) | 2002-10-08 |
| US20100249159A1 (en) | 2010-09-30 |
| EP1370552A2 (en) | 2003-12-17 |
| ATE353889T1 (de) | 2007-03-15 |
| DE60218138D1 (de) | 2007-03-29 |
| US20060142314A1 (en) | 2006-06-29 |
| AR035792A1 (es) | 2004-07-14 |
| WO2002076977A2 (en) | 2002-10-03 |
| JP2004528314A (ja) | 2004-09-16 |
| MXPA03008659A (es) | 2005-04-08 |
| JP4320705B2 (ja) | 2009-08-26 |
| US20030087919A1 (en) | 2003-05-08 |
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| Date | Code | Title | Description |
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| PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20130322 |