FR18C1012I1 - Derives de staurosporine inhibiteurs de l'activite tyrosine kinase du recepteur flt3 - Google Patents

Derives de staurosporine inhibiteurs de l'activite tyrosine kinase du recepteur flt3

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Publication number
FR18C1012I1
FR18C1012I1 FR18C1012C FR18C1012I1 FR 18C1012 I1 FR18C1012 I1 FR 18C1012I1 FR 18C1012 C FR18C1012 C FR 18C1012C FR 18C1012 I1 FR18C1012 I1 FR 18C1012I1
Authority
FR
France
Prior art keywords
tyrosine kinase
kinase activity
receptor tyrosine
flt3 receptor
staurosporine derivatives
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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English (en)
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Novartis AG
Dana Farber Cancer Institute Inc
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Novartis AG
Dana Farber Cancer Institute Inc
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26991080&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FR18C1012(I1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis AG, Dana Farber Cancer Institute Inc filed Critical Novartis AG
Publication of FR18C1012I1 publication Critical patent/FR18C1012I1/fr
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Publication of FR18C1012I2 publication Critical patent/FR18C1012I2/fr
Active legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/553—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
FR18C1012C 2001-10-30 2018-03-19 Derives de staurosporine inhibiteurs de l'activite tyrosine kinase du recepteur flt3 Active FR18C1012I2 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US33903101P 2001-10-30 2001-10-30
US33818501P 2001-12-07 2001-12-07
PCT/EP2002/012076 WO2003037347A1 (fr) 2001-10-30 2002-10-29 Derives de staurosporine inhibiteurs de l'activite tyrosine kinase du recepteur flt3

Publications (2)

Publication Number Publication Date
FR18C1012I1 true FR18C1012I1 (fr) 2018-04-27
FR18C1012I2 FR18C1012I2 (fr) 2021-06-11

Family

ID=26991080

Family Applications (1)

Application Number Title Priority Date Filing Date
FR18C1012C Active FR18C1012I2 (fr) 2001-10-30 2018-03-19 Derives de staurosporine inhibiteurs de l'activite tyrosine kinase du recepteur flt3

Country Status (26)

Country Link
US (3) US7973031B2 (fr)
EP (1) EP1441737B1 (fr)
JP (1) JP4959918B2 (fr)
KR (2) KR100926194B1 (fr)
CN (2) CN101703509A (fr)
AT (1) ATE335490T1 (fr)
AU (1) AU2006249245B2 (fr)
BR (1) BRPI0213739B8 (fr)
CA (1) CA2462657C (fr)
CY (1) CY1106199T1 (fr)
DE (1) DE60213842T2 (fr)
DK (1) DK1441737T3 (fr)
ES (1) ES2269793T3 (fr)
FR (1) FR18C1012I2 (fr)
HK (1) HK1068262A1 (fr)
HU (1) HU230798B1 (fr)
IL (2) IL161156A0 (fr)
MX (1) MXPA04004137A (fr)
NO (1) NO335685B1 (fr)
NZ (1) NZ532136A (fr)
PL (1) PL211461B1 (fr)
PT (1) PT1441737E (fr)
RU (1) RU2337692C3 (fr)
TW (1) TWI302836B (fr)
WO (1) WO2003037347A1 (fr)
ZA (1) ZA200402498B (fr)

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